検索結果 - 岡山大学学術成果リポジトリ

Surgical Treatment of Epiretinal Membrane

JaLCDOI	10.18926/AMO/62378
フルテキストURL	75_4_403.pdf
著者	Matoba, Ryo\| Morizane, Yuki\|
抄録	Epiretinal membrane (ERM) is a common retinal disease characterized by cellular proliferation and metaplasia that lead to the formation of a pathological fibrocellular membrane immediately superjacent to the inner retinal surface. The vast majority of ERMs are considered idiopathic. However, ERM formation can result from various primary intraocular diseases, including retinal breaks and detachment, retinal vascular diseases, and vitreoretinal inflammatory conditions. Although ERMs are generally asymptomatic or cause mild metamorphopsia and/or a modest decrease in visual acuity, some can cause severe macular distortion and macular edema, resulting in significantly impaired function. Surgical removal of ERM is the only treatment, and improvements in vitrectomy systems have enabled less invasive treatment. However, there are currently no standardized criteria for ERM surgery, and the indications for surgery are determined from the patient’s subjective symptoms. Another problem with ERM surgery is that not all patients show satisfactory postoperative recovery of visual function. Thus, further research is needed to determine the criteria for ERM surgery and methods to improve the postoperative prognosis.
キーワード	epiretinal membrane vitrectomy optical coherence tomography internal limiting membrane lamellar macular hole
Amo Type	Review
出版物タイトル	Acta Medica Okayama
発行日	2021-08
巻	75巻
号	4号
出版者	Okayama University Medical School
開始ページ	403
終了ページ	413
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34511606
Web of Science KeyUT	000697944600001
NAID	120007146059

New field‑in‑field with two reference points method for whole breast radiotherapy: Dosimetric analysis and radiation‑induced skin toxicities assessment

フルテキストURL	fulltext20210824-1.pdf
著者	Tekiki, Nouha\| Kuroda, Masahiro\| Ishizaka, Hinata\| Khasawneh, Abdullah\| Barham, Majd\| Hamada, Kentaro\| Konishi, Kohei\| Sugimoto, Kohei\| Katsui, Kuniaki\| Sugiyama, Soichi\| Watanabe, Kenta\| Yoshio, Kotaro\| Katayama, Norihisa\| Ogata, Takeshi\| Ihara, Hiroki\| Kanazawa, Susumu\| Asaumi, Junichi\|
キーワード	breast cancer field‑in‑field radiotherapy dose reference point acute skin toxicity dose distribution high‑dose area
備考	This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) License.\|
発行日	2021-7-21
出版物タイトル	Molecular and Clinical Oncology
巻	15巻
号	3号
出版者	Spandidos Publications
ISSN	2049-9450
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Tekiki et al.
論文のバージョン	publisher
PubMed ID	34349992
DOI	10.3892/mco.2021.2355
Web of Science KeyUT	000680476900001
関連URL	isVersionOf https://doi.org/10.3892/mco.2021.2355

Discovery and Validation of Nitroxoline as a Novel STAT3 Inhibitor in Drug-resistant Urothelial Bladder Cancer

フルテキストURL	fulltext.pdf
著者	Lin, Wenfeng\| Sun, Jingkai\| Sadahira, Takuya\| Xu, Naijin\| Wada, Koichiro\| Liu, Chunxiao\| Araki, Motoo\| Xu, Abai\| Watanabe, Masami\| Nasu, Yasutomo\| Huang, Peng\|
キーワード	Urothelial bladder cancer doxorubicin cisplatin chemoresistance nitroxoline STAT3
発行日	2021-07-25
出版物タイトル	International Journal of Biological Sciences
巻	17巻
号	12号
出版者	Ivyspring International Publisher
開始ページ	3255
終了ページ	3267
ISSN	1449-2288
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The author(s).
論文のバージョン	publisher
DOI	10.7150/ijbs.63125
Web of Science KeyUT	000682847000007
関連URL	isVersionOf https://doi.org/10.7150/ijbs.63125

Photocontrolled apoptosis induction using precursor miR-664a and an RNA carrier-conjugated with photosensitizer

フルテキストURL	fulltext.pdf
著者	Watanabe, Kazunori\| Nawachi, Tomoko\| Okutani, Ruriko\| Ohtsuki, Takashi\|
発行日	2021-07-22
出版物タイトル	scientific reports
巻	11巻
号	1号
出版者	Nature Portfolio
開始ページ	14936
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2021
論文のバージョン	publisher
PubMed ID	34294789
DOI	10.1038/s41598-021-94249-7
Web of Science KeyUT	000682800400009
関連URL	isVersionOf https://doi.org/10.1038/s41598-021-94249-7

Association of blood pressure and renal outcome in patients with chronic kidney disease; a post hoc analysis of FROM-J study

フルテキストURL	fulltext.pdf
著者	Tsuchida-Nishiwaki, Mariko\| Uchida, Haruhito A.\| Takeuchi, Hidemi\| Nishiwaki, Noriyuki\| Maeshima, Yohei\| Saito, Chie\| Sugiyama, Hitoshi\| Wada, Jun\| Narita, Ichiei\| Watanabe, Tsuyoshi\| Matsuo, Seiichi\| Makino, Hirofumi\| Hishida, Akira\| Yamagata, Kunihiro\|
発行日	2021-07-22
出版物タイトル	Scientific Reports
巻	11巻
号	1号
出版者	Nature Portfolio
開始ページ	14990
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2021
論文のバージョン	publisher
PubMed ID	34294784
DOI	10.1038/s41598-021-94467-z
Web of Science KeyUT	000682802200023
関連URL	isVersionOf https://doi.org/10.1038/s41598-021-94467-z

Triple therapy with osimertinib, bevacizumab and cetuximab in EGFR‑mutant lung cancer with HIF‑1α/TGF‑α expression

フルテキストURL	fulltext20210810-3.pdf
著者	Nishii, Kazuya\| Ohashi, Kadoaki\| Watanabe, Hiromi\| Makimoto, Go\| Nakasuka, Takamasa\| Higo, Hisao\| Ninomiya, Kiichiro\| Kato, Yuka\| Kubo, Toshio\| Rai, Kammei\| Ichihara, Eiki\| Hotta, Katsuyuki\| Tabata, Masahiro\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
キーワード	epidermal growth factor receptor osimertinib bevacizumab cetuximab hypoxia‑inducible factor‑1α transforming growth factor‑α
発行日	2021-7-7
出版物タイトル	Oncology Letters
巻	22巻
号	3号
出版者	Spandidos Publications
開始ページ	639
ISSN	1792-1074
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Nishii et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
論文のバージョン	publisher
DOI	10.3892/ol.2021.12900
Web of Science KeyUT	000678494600001
関連URL	isVersionOf https://doi.org/10.3892/ol.2021.12900

Serodiagnosis and Bacterial Genome of Helicobacter pylori Infection

フルテキストURL	fulltext.pdf
著者	Ichihara, Aina\| Ojima, Hinako\| Gotoh, Kazuyoshi\| Matsushita, Osamu\| Take, Susumu\| Okada, Hiroyuki\| Watanabe, Akari\| Yokota, Kenji\|
キーワード	antibody VacA CagA genome
発行日	2021-07-05
出版物タイトル	toxins
巻	13巻
号	7号
出版者	MDPI
開始ページ	467
ISSN	2072-6651
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 by the authors.
論文のバージョン	publisher
DOI	10.3390/toxins13070467
Web of Science KeyUT	000677052200001
関連URL	isVersionOf https://doi.org/10.3390/toxins13070467

ABO Blood Incompatibility Positively Affects Early Graft Function: Single-Center Retrospective Cohort Study

フルテキストURL	fulltext20210721-2.pdf figure20210721-2.pdf
著者	Watari, Shogo\| Araki, Motoo\| Wada, Koichiro\| Yoshinaga, Kasumi\| Maruyama, Yuki\| Mitsui, Yosuke\| Sadahira, Takuya\| Kubota, Risa\| Nishimura, Shingo\| Kobayashi, Yasuyuki\| Takeuchi, Hidemi\| Tanabe, Katsuyuki\| Kitagawa, Masashi\| Morinaga, Hiroshi\| Kitamura, Shinji\| Sugiyama, Hitoshi\| Wada, Jun\| Watanabe, Masami\| Watanabe, Toyohiko\| Nasu, Yasutomo\|
備考	© 2021 Published by Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.transproceed.2021.03.043] . \|
発行日	2021-4-28
出版物タイトル	Transplantation Proceedings
巻	53巻
号	5号
出版者	Elsevier BV
開始ページ	1494
終了ページ	1500
ISSN	0041-1345
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	33931247
DOI	10.1016/j.transproceed.2021.03.043
Web of Science KeyUT	000668604400017
関連URL	isVersionOf https://doi.org/10.1016/j.transproceed.2021.03.043

Anti-Inflammatory Effect on Colitis and Modulation of Microbiota by Fermented Plant Extract Supplementation

フルテキストURL	fulltext.pdf
著者	Sugimoto, Manabu\| Watanabe, Toshiro\| Takaoka, Motoko\| Suzuki, Kyoko\| Murakami, Tadatoshi\| Murakami, Nobutada\| Sumikawa, Shoichi\|
キーワード	fermented plant extract microbiota dextran sulfate sodium inflammatory Clostridiales
発行日	2021-04-06
出版物タイトル	Fermentation-Basel
巻	7巻
号	2号
出版者	MDPI
開始ページ	55
ISSN	2311-5637
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 by the authors.
論文のバージョン	publisher
DOI	10.3390/fermentation7020055
Web of Science KeyUT	000665199500001
関連URL	isVersionOf https://doi.org/10.3390/fermentation7020055

Osteopontin silencing attenuates bleomycin-induced murine pulmonary fibrosis by regulating epithelial-mesenchymal transition

フルテキストURL	fulltext.pdf
著者	Hatipoglu, Omer Faruk\| Uctepe, Eyyup\| Opoku, Gabriel\| Wake, Hidenori\| Ikemura, Kentaro\| Ohtsuki, Takashi\| Inagaki, Junko\| Gunduz, Mehmet\| Gunduz, Esra\| Watanabe, Shogo\| Nishinaka, Takashi\| Takahashi, Hideo\| Hirohata, Satoshi\|
キーワード	Pulmonary fibrosis Osteopontin Epithelial-mesenchymal transition
発行日	2021-07
出版物タイトル	Biomedicine & Pharmacotherapy
巻	139巻
出版者	Elsevier France-Editions Scientifiques Medicales e
開始ページ	111633
ISSN	0753-3322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 The Author(s).
論文のバージョン	publisher
DOI	10.1016/j.biopha.2021.111633
Web of Science KeyUT	000663683300007
関連URL	isVersionOf https://doi.org/10.1016/j.biopha.2021.111633

The effect of Humanitude care methodology on improving empathy: a six-year longitudinal study of medical students in Japan

フルテキストURL	fulltext.pdf
著者	Fukuyasu, Yusuke\| Kataoka, Hitomi U.\| Honda, Miwako\| Iwase, Toshihide\| Ogawa, Hiroko\| Sato, Masaru\| Watanabe, Mayu\| Fujii, Chikako\| Wada, Jun\| DeSantis, Jennifer\| Hojat, Mohammadreza\| Gonnella, Joseph S.\|
キーワード	Empathy Humanitude Medical education
発行日	2021-06-04
出版物タイトル	BMC Medical Education
巻	21巻
号	1号
出版者	BMC
開始ページ	316
ISSN	1472-6920
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s). 2021
論文のバージョン	publisher
PubMed ID	34088308
NAID	120007089818
DOI	10.1186/s12909-021-02773-x
Web of Science KeyUT	000660873600001
関連URL	isVersionOf https://doi.org/10.1186/s12909-021-02773-x

A Case of Metastatic Fumarate Hydratase-Deficient–like Renal Cell Carcinoma Successfully Managed by Ipilimumab plus Nivolumab

JaLCDOI	10.18926/AMO/62237
フルテキストURL	75_3_397.pdf
著者	Sekito, Takanori\| Takamoto, Atsushi\| Kobayashi, Yasuyuki\| Mitsui, Masao\| Watari, Shogo\| Kubota, Risa\| Sadahira, Takuya\| Iwata, Takehiro\| Nishimura, Shingo\| Edamura, Kohei\| Sako, Tomoko\| Araki, Motoo\| Watanabe, Masami\| Watanabe, Toyohiko\| Shibata, Rei\| Ennishi, Daisuke\| Nasu, Yasutomo\|
抄録	We report a 62-year-old male with metastatic fumarate hydratase-deficient renal cell carcinoma (FH-deficient RCC) without fumarate hydratase (FH) mutation (FH-deficient–like RCC). The International Metastatic RCC Database Consortium risk score was intermediate, and immunotherapy with nivolumab and ipilimumab (Ipi/ Nivo) was initiated. Four cycles of Ipi/Nivo and 5 cycles of nivolumab resulted in a complete response of the metastases. Hypophysitis occurred as an immune-related adverse event after four cycles of Ipi/Nivo. The prognosis of patients with FH-deficient RCC is generally poor. Few reports of FH-deficient RCC successfully treated with Ipi/Nivo have been published. Ipi/Nivo can be effective for treating FH-deficient RCC.
キーワード	fumarate hydratase fumarate hydratase-deficient renal cell carcinoma renal cell carcinoma ipilimumab nivolumab
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-06
巻	75巻
号	3号
出版者	Okayama University Medical School
開始ページ	397
終了ページ	402
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34176946
Web of Science KeyUT	000667147700017
NAID	120007089822

Texture Indices of 18F-FDG PET/CT for Differentiating Squamous Cell Carcinoma and Non-Hodgkin’s Lymphoma of the Oropharynx

JaLCDOI	10.18926/AMO/62230
フルテキストURL	75_3_351.pdf
著者	Mitamura, Katsuya\| Norikane, Takashi\| Yamamoto, Yuka\| Ihara-Nishishita, Ayumi\| Kobata, Takuya\| Fujimoto, Kengo\| Takami, Yasukage\| Kudomi, Nobuyuki\| Hoshikawa, Hiroshi\| Nishiyama, Yoshihiro\|
抄録	We assessed the role of 18F-FDG PET/CT texture indices for the differentiation of squamous cell carcinoma (SCC) and non-Hodgkin’s lymphoma (NHL) in the oropharynx. 18F-FDG PET/CT data for 27 patients with SCC and 25 patients with NHL in the oropharynx were investigated. The maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV), total lesion glycolysis (TLG), and six texture indices (homogeneity, entropy, short-run emphasis, long-run emphasis, low gray-level zone emphasis [LGZE], and high graylevel zone emphasis [HGZE]) were derived from PET images. PET/CT parameters of the SCC patients were compared with those of the NHL patients. The diagnostic accuracy of the indices for differentiating SCC from NHL was calculated by a receiver operating characteristic curve analysis. 18F-FDG uptake in the oropharynx was observed in all of the patients. The SUVmax, MTV, and TLG did not differ significantly between the SCC and NHL groups, but two of the six texture indices (LGZE [p=0.004] and HGZE [p=0.03]) showed significant differences between the groups. LGZE was the best discriminative index for the differentiation of SCC and NHL (55.6% sensitivity, 88.0% specificity). The LGZE and HGZE texture indices derived from 18F-FDG PET/CT images may be useful in differentiating SCC and NHL in the oropharynx.
キーワード	18F-FDG PET/CT oropharyngeal squamous cell carcinoma malignant lymphoma texture
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-06
巻	75巻
号	3号
出版者	Okayama University Medical School
開始ページ	351
終了ページ	356
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34176939
Web of Science KeyUT	000667147700010
NAID	120007089827

Predictors of Hypotension after Adrenalectomy for Pheochromocytoma

JaLCDOI	10.18926/AMO/62229
フルテキストURL	75_3_345.pdf
著者	Koyama, Kanae\| Miura, Noriyoshi\| Watanabe, Ryuta\| Sawada, Yuichiro\| Noda, Terutaka\| Nishimura, Kenichi\| Asai, Seiji\| Fukumoto, Tetsuya\| Yanagihara, Yutaka\| Miyauchi, Yuki\| Kikugawa, Tadahiko\| Saika, Takashi\|
抄録	The management of blood pressure is a significant concern for surgeons and anesthesiologists performing adrenalectomy for pheochromocytoma. We evaluated clinical factors in pheochromocytoma patients to identify the predictors of postoperative hypotension. The medical records of patients who underwent adrenalectomy for pheochromocytoma between 2001 and 2017 were retrospectively reviewed and clinical and biochemical data were evaluated. Of 29 patients, 13 patients needed catecholamine support in the perisurgical period while 16 patients did not. There were significant differences in median age, tumor size, and blood pressure drop (maxmin) between the 2 groups (68 vs 53 years old, p=0.045; 50 vs 32 mm diameter, p=0.022; 110 vs 71 mmHg, p=0.015 respectively). In univariate logistic analysis, age > 65.5 years, tumor size > 34.5 mm, urine metanephrine > 0.205 mg/day and urine normetanephrine > 0.665 mg/day were significant predictors of prolonged hypotension requiring postoperative catecholamine support. Tumor size and urine metanephrine and urine normetanephrine levels were correlated with postoperative hypotension. These predictors may help in the safe perioperative management of pheochromocytoma patients treated with adrenalectomy.
キーワード	urinary metanephrine urinary normetanephrine adrenalectomy pheochromocytoma
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-06
巻	75巻
号	3号
出版者	Okayama University Medical School
開始ページ	345
終了ページ	349
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34176938
Web of Science KeyUT	000667147700009
NAID	120007089826

Validity and Reliability of the Japanese Version of the 12-item Self-administered World Health Organization Disability Assessment Schedule (WHODAS) 2.0 in Patients with Schizophrenia

JaLCDOI	10.18926/AMO/62226
フルテキストURL	75_3_315.pdf
著者	Wada, Riho\| Fujiwara, Masaki\| Yamada, Yuto\| Nakaya, Naoki\| Fujimori, Maiko\| So, Ryuhei\| Kodama, Masafumi\| Higuchi, Yuji\| Kakeda, Kyoko\| Uchitomi, Yosuke\| Yamada, Norihito\| Inagaki, Masatoshi\|
抄録	It is necessary to assess functional impairment when treating schizophrenia. The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) has been adopted as a measure of functional disability in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. This study was a secondary analysis from a cross-sectional study of health-related behaviors among patients with schizophrenia. We examined the validity and reliability of the Japanese version of the 12-item WHODAS 2.0 when self-administered by such patients. Participants were 350 outpatients with schizophrenia from a psychiatric hospital. The standard six-factor structure of the WHODAS 2.0 showed a good fit for these participants. The Cronbach’s alpha coefficient was 0.858, showing good internal consistency. The WHODAS 2.0 showed moderate correlations with the modified Global Assessment of Functioning and Kessler 6 scales (r=−0.434 and 0.555, respectively). The results of this study show that the Japanese version of the 12-item self-administered WHODAS 2.0 has good internal consistency and convergent validity among patients with schizophrenia. Further exploration of the usefulness of WHODAS 2.0 in clinical settings is needed.
キーワード	disability schizophrenia validity reliability WHODAS 2.0
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-06
巻	75巻
号	3号
出版者	Okayama University Medical School
開始ページ	315
終了ページ	322
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34176935
NAID	120007089823

Investigation into the Effect of Breast Volume on Irradiation Dose Distribution in Asian Women with Breast Cancer

JaLCDOI	10.18926/AMO/62225
フルテキストURL	75_3_307.pdf
著者	Ishizaka, Hinata\| Kuroda, Masahiro\| Tekiki, Nouha\| Khasawneh, Abdullah\| Barham, Majd\| Hamada, Kentaro\| Konishi, Kohei\| Sugimoto, Kohei\| Katsui, Kuniaki\| Sugiyama, Soichi\| Watanabe, Kenta\| Yoshio, Kotaro \| Katayama, Norihisa\| Ogata, Takeshi\| Ihara, Hiroki\| Oita, Masataka\| Kanazawa, Susumu\| Asaumi, Junichi\|
抄録	Reports on irradiation dose distribution in breast cancer radiotherapy with sufficient sample size are limited in Asian patients. Elucidating dose distribution in Asian patients is particularly important as their breast volume differs compared to patients in Europe and North America. Here, we examined dose distribution in the irradiation field relative to breast volume for three irradiation methods historically used in our facility. We investigated the influence of breast volume on each irradiation method for Asian women. A total of 573 women with early-stage breast cancer were treated with breast-conserving surgery and adjuvant radiotherapy. Three methods were compared: wedge (W), field-in-field (FIF), and wedge-field-in-field (W-FIF). In patients with small breast volume, FIF decreased low- and high-dose areas within the planning target volume, and increased optimal dose area more than W. In patients with medium and large breast volumes, FIF decreased high-dose area more than W. The absolute values of correlation coefficients of breast volume to low-, optimal-, and high-dose areas and mean dose were significantly lower in FIF than in W. The correlation coefficients of V107% were 0.00 and 0.28 for FIF and W, respectively. FIF is an excellent irradiation method that is less affected by breast volume than W in Asian breast cancer patients.
キーワード	breast cancer radiotherapy dose distribution irradiation method breast volume
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-06
巻	75巻
号	3号
出版者	Okayama University Medical School
開始ページ	307
終了ページ	314
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34176934
Web of Science KeyUT	000667147700006
NAID	120007089838

Clinical Outcome of Palliative Concurrent Chemoradiotherapy with Cisplatin/Docetaxel for Stage III Non-small Cell Lung Cancer

JaLCDOI	10.18926/AMO/62218
フルテキストURL	75_3_269.pdf
著者	Katsui, Kuniaki\| Ogata, Takeshi\| Watanabe, Kenta\| Yoshio, Kotaro\| Kuroda, Masahiro\| Hiraki, Takao\| Kiura, Katsuyuki\| Maeda, Yoshinobu\| Toyooka, Shinichi\| Kanazawa, Susumu\|
抄録	Palliative concurrent chemoradiotherapy (CCRT) is often administered to patients with stage III non-small cell lung cancer (NSCLC). We investigated the clinical outcomes of patients receiving palliative CCRT for NSCLC. Data of patients with NSCLC who underwent palliative CCRT (n=16), preoperative CCRT plus surgery (n=97), or definitive CCRT (n=48) were evaluated. In all groups, the concurrent chemotherapy regimens consisted of cisplatin and docetaxel. Rates of local control (LC), distant metastasis-free survival (DMFS), progression-free survival (PFS), overall survival (OS), and prognosis were compared. The 2-year rates of LC, DMFS, PFS, and OS in 16 patients who underwent palliative CCRT were 44.4%, 12.5%, 12.5%, and 18.8%, respectively. Univariate analysis showed that palliative CCRT was associated with poor LC (p<0.001), DMFS (p<0.001), PFS (p<0.001), and OS (p<0.001) outcomes in patients who completed CCRT as a preoperative treatment and poor LC (p=0.01), DMFS (p=0.003), PFS (p=0.04), and OS (p=0.004) outcomes in patients who were considered for definitive CCRT. Although there were some long-term survivors, the clinical outcomes of palliative CCRT were significantly inferior to those of the ideal treatments. Therefore, careful determination of the appropriate treatment indications and further studies are warranted.
キーワード	palliative concurrent chemoradiotherapy cisplatin/docetaxel stage III non-small cell lung cancer
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-06
巻	75巻
号	3号
出版者	Okayama University Medical School
開始ページ	269
終了ページ	277
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34176930
Web of Science KeyUT	000667147700002
NAID	120007089833

Feasible kidney donation with living marginal donors, including diabetes mellitus

フルテキストURL	fulltext.pdf
著者	Yoshinaga, Kasumi\| Araki, Motoo\| Wada, Koichiro\| Sekito, Takanori\| Watari, Shogo\| Maruyama, Yuki\| Mitsui, Yosuke\| Sadahira, Takuya\| Kubota, Risa\| Nishimura, Shingo\| Edamura, Kohei\| Kobayashi, Yasuyuki\| Tanabe, Katsuyuki\| Takeuchi, Hidemi\| Kitagawa, Masashi\| Kitamura, Shinji\| Wada, Jun\| Watanabe, Masami\| Watanabe, Toyohiko\| Nasu, Yasutomo\|
キーワード	diabetes mellitus kidney function kidney transplantation marginal donor
発行日	2021-06-08
出版物タイトル	Immunity Inflammation and Disease
出版者	Wiley
ISSN	2050-4527
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 The Authors.
論文のバージョン	publisher
PubMed ID	34102025
NAID	120007053366
DOI	10.1002/iid3.470
Web of Science KeyUT	000658836600001
関連URL	isVersionOf https://doi.org/10.1002/iid3.470

Novel Urinary Glycan Biomarkers Predict Cardiovascular Events in Patients With Type 2 Diabetes: A Multicenter Prospective Study With 5-Year Follow Up (U-CARE Study 2)

フルテキストURL	fulltext.pdf
著者	Mise, Koki\| Imamura, Mariko\| Yamaguchi, Satoshi\| Watanabe, Mayu\| Higuchi, Chigusa\| Katayama, Akihiro\| Miyamoto, Satoshi\| Uchida, Haruhito A.\| Nakatsuka, Atsuko\| Eguchi, Jun\| Hida, Kazuyuki\| Nakato, Tatsuaki\| Tone, Atsuhito\| Teshigawara, Sanae\| Matsuoka, Takashi\| Kamei, Shinji\| Murakami, Kazutoshi\| Shimizu, Ikki\| Miyashita, Katsuhiro\| Ando, Shinichiro\| Nunoue, Tomokazu\| Yoshida, Michihiro\| Yamada, Masao\| Shikata, Kenichi\| Wada, Jun\|
キーワード	cardiovascular event diabetes lectins N-glycans urinary biomarkers
発行日	2021-05-24
出版物タイトル	Frontiers In Cardiovascular Medicine
巻	8巻
出版者	Frontiers Media SA
開始ページ	668059
ISSN	2297-055X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 by the authors.
論文のバージョン	publisher
PubMed ID	34109226
NAID	120007053373
DOI	10.3389/fcvm.2021.668059
Web of Science KeyUT	000658156400001
関連URL	isVersionOf https://doi.org/10.3389/fcvm.2021.668059

Efficacy and safety of short-term (3 days) enoxaparin in preventing venous thromboembolism after gastric cancer surgery: A single-center, prospective cohort study

フルテキストURL	fulltext20210608-1.pdf highlights20210608-1.pdf figure20210608-1.pdf table20210608-1.pdf supplement20210608-1.pdf
著者	Kuroda, Shinji\| Kikuchi, Satoru\| Kakiuchi, Yoshihiko\| Watanabe, Megumi\| Kuwada, Kazuya\| Tsumura, Tomoko\| Nishizaki, Masahiko\| Kagawa, Shunsuke\| Hinotsu, Shiro\| Fujiwara, Toshiyoshi\|
備考	This is an Accepted Manuscript of an article published by Elsevier BV. © 2021 IJS Publishing Group Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.ijsu.2021.105946] . \|
発行日	2021-5
出版物タイトル	International Journal of Surgery
巻	89巻
出版者	Elsevier BV
開始ページ	105946
ISSN	1743-9191
NCID	AA12063080
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 IJS Publishing Group Ltd.
論文のバージョン	author
PubMed ID	33892160
DOI	10.1016/j.ijsu.2021.105946
Web of Science KeyUT	000651625600016
関連URL	isVersionOf https://doi.org/10.1016/j.ijsu.2021.105946