検索結果 - 岡山大学学術成果リポジトリ

RUNX2 Phosphorylation by Tyrosine Kinase ABL Promotes Breast Cancer Invasion

フルテキストURL	fulltext.pdf
著者	He, Fang\| Matsumoto, Yoshinori\| Asano, Yosuke\| Yamamura, Yuriko\| Katsuyama, Takayuki\| La Rose, Jose\| Tomonobu, Nahoko\| Komalasari, Ni Luh Gede Yoni\| Sakaguchi, Masakiyo\| Rottapel, Robert\| Wada, Jun\|
キーワード	ABL Abelson murine leukemia viral oncogene homolog Runx2 (runt-related transcription factor 2) tyrosine phosphorylation invasion
備考	Erratum in https://ousar.lib.okayama-u.ac.jp/62331\|
発行日	2021-05-31
出版物タイトル	Frontiers In Oncology
巻	11巻
出版者	Frontiers Media S.A.
開始ページ	665273
ISSN	2234-943X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 He, Matsumoto, Asano, Yamamura, Katsuyama, La Rose, Tomonobu, Komalasari, Sakaguchi, Rottapel and Wada.
論文のバージョン	publisher
PubMed ID	34136397
DOI	10.3389/fonc.2021.665273
NAID	120007089841
Web of Science KeyUT	000661158800001
関連URL	isVersionOf https://doi.org/10.3389/fonc.2021.665273

Relationships of physical and breast cancer phenotypes with three single-nucleotide polymorphisms (rs2046210, rs3757318 and rs3803662) associated with breast cancer risk in jpnpanese women

フルテキストURL	K0006308_abstract_review　.pdf K0006308_fulltext.pdf K0006308_other1.pdf K0006308_other2.pdf
著者	河田健吾\|
発行日	2021-03-25
資料タイプ	学位論文
学位授与番号	甲第6308号
学位授与年月日	2021-03-25
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語

Successful Treatment of Acute Promyelocytic Leukemia Complicated with Endometrial Cancer by Arsenic Trioxide

JaLCDOI	10.18926/AMO/61904
フルテキストURL	75_2_219.pdf
著者	Sugiura, Hiroyuki\| Nishimori, Hisakazu\| Matsuoka, Hirofumi\| Nakamura, Keiichiro\| Fujii, Keiko\| Fujii, Nobuharu \| Matsuoka, Ken-ichi \| Maeda, Yoshinobu\|
抄録	Acute promyelocytic leukemia (APL) is a hematological emergency that requires urgent intervention because of the high incidence of early hemorrhagic death. When patients with APL experience a synchronous solid organ tumor, the tumor’s treatment must also be done properly. Differentiation-inducing therapy using arsenic trioxide (ATO) has less hematological toxicity compared to cytotoxic chemotherapy and might be preferable for untreated APL patients with a synchronous solid organ tumor. Here we describe the first successful case of untreated APL and synchronous endometrial cancer (in an adult Japanese woman) treated with ATO consolidation therapy and the subsequent surgery and chemotherapy for endometrial cancer.
キーワード	acute promyelocytic leukemia endometrial cancer arsenic trioxide synchronous multiple primary malignant tumor chemotherapy
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-04
巻	75巻
号	2号
出版者	Okayama University Medical School
開始ページ	219
終了ページ	224
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33953429
NAID	120007029883

Lactoferrin-like Immunoreactivity in Distinct Neuronal Populations in the Mouse Central Nervous System

JaLCDOI	10.18926/AMO/61894
フルテキストURL	75_2_153.pdf
著者	Shimaoka, Shigeyoshi\| Hamaoka, Hitomi\| Inoue, Junji\| Asanuma, Masato\| Tooyama, Ikuo\| Kondo, Yoichi\|
抄録	Lactoferrin (Lf) is an iron-binding glycoprotein mainly found in exocrine secretions and the secondary granules of neutrophils. In the central nervous system (CNS), expression of the Lf protein has been reported in the lesions of some neurodegenerative disorders such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis, as well as in the aged brain. Lf is primarily considered an iron chelator, protecting cells from potentially toxic iron or iron-requiring microorganisms. Other biological functions of Lf include immunomodulation and transcriptional regulation. However, the roles of Lf in the CNS have yet to be fully clarified. In this study, we raised an antiserum against mouse Lf and investigated the immunohistochemical localization of Lf-like immunoreactivity (Lf-LI) throughout the CNS of adult mice. Lf-LI was found in some neuronal populations throughout the CNS. Intense labeling was found in neurons in the olfactory systems, hypothalamic nuclei, entorhinal cortex, and a variety of brainstem nuclei. This study provides detailed information on the Lf-LI distribution in the CNS, and the findings should promote further understanding of both the physiological and pathological significance of Lf in the CNS.
キーワード	lactoferrin immunohistochemistry brain mapping
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-04
巻	75巻
号	2号
出版者	Okayama University Medical School
開始ページ	153
終了ページ	167
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33953422
NAID	120007029892

Evaluation of the Imaging Process for a Novel Subtraction Method Using Apparent Diffusion Coefficient Values

JaLCDOI	10.18926/AMO/61880
フルテキストURL	75_2_139.pdf
著者	Hamada, Kentaro\| Kuroda, Masahiro\| Yoshimura, Yuuki \| Khasawneh, Abdullah\| Barham, Majd\| Tekiki, Nouha\| Sugianto, Irfan\| Bamgbose, Babatunde O.\| Konishi, Kohei\| Sugimoto, Kohei\| Ishizaka, Hinata\| Kurozumi, Akira\| Matsushita, Toshi \| Ohno, Seiichiro\| Kanazawa, Susumu\| Asaumi, Junichi\|
抄録	Diffusion-weighted imaging may be used to obtain the apparent diffusion coefficient (ADC), which aids the diagnosis of cerebral infarction and tumors. An ADC reflects elements of free diffusion. Diffusion kurtosis imaging (DKI) has attracted attention as a restricted diffusion imaging technique. The ADC subtraction method (ASM) was developed to visualize restricted diffusion with high resolution by using two ADC maps taken with different diffusion times. We conducted the present study to provide a bridge between the reported basic ASM research and clinical research. We developed new imaging software for clinical use and evaluated its performance herein. This software performs the imaging process automatically and continuously at the pixel level, using ImageJ software. The new software uses a macro or a plugin which is compatible with various operating systems via a Java Virtual Machine. We tested the new imaging software’s performance by using a Jurkat cell bio-phantom, and the statistical evaluation of the performance clarified that the ASM values of 99.98% of the pixels in the bio-phantom and physiological saline were calculated accurately (p<0.001). The new software may serve as a useful tool for future clinical applications and restricted diffusion imaging research.
キーワード	apparent diffusion coefficient ADC subtraction method restricted diffusion ImageJ plugin
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-04
巻	75巻
号	2号
出版者	Okayama University Medical School
開始ページ	139
終了ページ	145
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33953420
NAID	120007029903

Efficacy and Safety of Ramucirumab/nab-paclitaxel for Previously Treated Advanced Gastric Cancer in Community Hospitals

JaLCDOI	10.18926/AMO/61879
フルテキストURL	75_2_133.pdf
著者	Hashida, Shinsuke\| Tanaka, Norimitsu\| Takahashi, Yuta\| Onoda, Yuji\| Colvin, Hugh Shunsuke\| Ohashi, Ryuichiro\| Okamoto, Kunio \|
抄録	As the nanoparticle albumin-bound paclitaxel (nab-PTX) is free of ethanol and premedication, the duration of administration is shorter and patients can drive themselves to and from the hospital. In the 2018 Japanese gastric cancer treatment guidelines, ramucirumab (RAM) plus weekly nab-PTX is conditionally recommended for previously treated patients with advanced gastric cancer. Here, we retrospectively analysed the efficacy and safety of RAM+nab-PTX for such patients in community hospitals. From January 2018 to December 2019, 43 patients with metastatic and recurrent gastric cancer received RAM+nab-PTX treatment. Six patients (13.9%) were older than 80 years and 9 patients (20.9%) showed ECOG-PS 2. Progression-free survival (PFS), overall survival (OS), overall response rate (ORR), disease control rate (DCR), and adverse events (AEs) were reviewed retrospectively. Median PFS was 114 days (95% confidence interval [CI]: 84-190) and median OS was 297 days (95% CI: 180-398). ORR and DCR were 32.4% and 72.2%, respectively. The incidence rates of ≥grade 3 neutropenia and febrile neutropenia were 53.5% and 2.3%, respectively. No treatment-related deaths occurred. RAM plus nab-PTX combination therapy demonstrated manageable toxicity even patients who were elderly or had an ECOG-PS 2. This treatment is useful in community hospital settings.
キーワード	gastric cancer ramucirumab nab-paclitaxel
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-04
巻	75巻
号	2号
出版者	Okayama University Medical School
開始ページ	133
終了ページ	138
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33953419
NAID	120007029904

RFX1‐mediated CCN3 induction that may support chondrocyte survival under starved conditions

フルテキストURL	fulltext20210407_3.pdf
著者	Mizukawa, Tomomi\| Nishida, Takashi\| Akashi, Sho\| Kawata, Kazumi\| Kikuchi, Sumire\| Kawaki, Harumi\| Takigawa, Masaharu\| Kamioka, Hiroshi\| Kubota, Satoshi\|
備考	This is an Accepted Manuscript of an article published by Wiley\| This fulltext is available in Mar 2022\|
発行日	2021-03-03
出版物タイトル	Journal of Cellular Physiology
出版者	Wiley
ISSN	0021-9541
NCID	AA00694856
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	33655492
DOI	10.1002/jcp.30348
Web of Science KeyUT	000624456400001
関連URL	isVersionOf https://doi.org/10.1002/jcp.30348

The HMGB1/RAGE axis induces bone pain associated with colonization of 4T1 mouse breast cancer in bone

フルテキストURL	fulltext20210506_2.pdf
著者	Okui, Tatsuo\| Hiasa, Masahiro\| Ryumon, Shoji\| Ono, Kisho\| Kunisada, Yuki\| Ibaragi, Soichiro\| Sasaki, Akira\| Roodman, G. David\| White, Fletcher A.\| Yoneda, Toshiyuki\|
キーワード	Breast cancer Bone pain Sensory neurons HMGB1 RAGE
発行日	2021-02-28
出版物タイトル	Journal of Bone Oncology
巻	26巻
出版者	Elsevier
開始ページ	100330
ISSN	22121374
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2020 The Authors.
論文のバージョン	publisher
PubMed ID	33204606
DOI	10.1016/j.jbo.2020.100330
Web of Science KeyUT	000625035900001
関連URL	isVersionOf https://doi.org/10.1016/j.jbo.2020.100330

Prospective cohort study of febrile neutropenia in breast cancer patients administered with neoadjuvant and adjuvant chemotherapies: CSPOR-BC FN study

フルテキストURL	fulltext20210527_4.pdf
著者	Ishikawa, Takashi\| Sakamaki, Kentaro\| Narui, Kazutaka\| Nishimura, Hideki\| Sangai, Takafumi\| Tamaki, Kentaro\| Hasegawa, Yoshie\| Watanabe, Ken-ichi\| Suganuma, Nobuyasu\| Michishita, Shintaro\| Sugae, Sadatoshi\| Aihara, Tomohiko\| Tsugawa, Koichiro\| Kaise, Hirose\| Taira, Naruto\| Mukai, Hirofumi\|
キーワード	Breast cancer Febrile neutropenia Adjuvant chemotherapy Risk factors Prospective study
発行日	2021-04-30
出版物タイトル	The Breast
巻	56巻
出版者	Elsevier
開始ページ	70
終了ページ	77
ISSN	09609776
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 The Author(s).
論文のバージョン	publisher
PubMed ID	33631458
DOI	10.1016/j.breast.2021.01.005
Web of Science KeyUT	000632058800010
関連URL	isVersionOf https://doi.org/10.1016/j.breast.2021.01.005

Covalent N-arylation by the pollutant 1,2-naphthoquinone activates the EGF receptor

フルテキストURL	fulltext20210530_3.pdf
著者	Nakahara, Kengo\| Hamada, Kyohei\| Tsuchida, Tomoki\| Takasugi, Nobumasa\| Abiko, Yumi\| Shien, Kazuhiko\| Toyooka, Shinichi\| Kumagai, Yoshito\| Uehara, Takashi\|
キーワード	epidermal growth factor receptor cell signaling chemical modification signal transduction apoptosis
発行日	2021-12-31
出版物タイトル	Journal of Biological Chemistry
巻	296巻
出版者	Elsevier
開始ページ	100524
ISSN	00219258
NCID	AA00251083
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 The Authors.
論文のバージョン	publisher
PubMed ID	33705793
DOI	10.1016/j.jbc.2021.100524
関連URL	isVersionOf https://doi.org/10.1016/j.jbc.2021.100524

Role of surgery in a novel multimodal therapeutic approach to complete cure of advanced lung cancer: current and future perspectives

フルテキストURL	fulltext.pdf
著者	Yamane, Masaomi\| Toyooka, Shinichi\|
キーワード	Lung cancer Perioperative therapy Surgery
備考	This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00595-021-02228-2.\|
発行日	2021-03-18
出版物タイトル	Surgery Today
出版者	Springer
ISSN	0941-1291
NCID	AA10824685
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	33738585
DOI	10.1007/s00595-021-02228-2
Web of Science KeyUT	000630247200002
関連URL	isVersionOf https://doi.org/10.1007/s00595-021-02228-2

Best practices for the extraction of genomic DNA from formalin‐fixed paraffin‐embedded tumor tissue for cancer genomic profiling tests

フルテキストURL	fulltext.pdf
著者	Inoue, Hirofumi\| Tomida, Shuta\| Horiguchi, Shigeru\| Kato, Hironari\| Matsuoka, Hiromi\| Sanehira, Etsuko\| Matsuoka, Masashi\| Yanai, Hiroyuki\| Hirasawa, Akira\| Toyooka, Shinichi\|
キーワード	cancer genomic profiling tests formalin‐fixed paraffin‐embedded (FFPE) tumor tissue genomic DNA extraction
備考	This is the peer reviewed version of the following article: Hirofumi Inoue et. al. Best practices for the extraction of genomic DNA from formalin‐fixed paraffin‐embedded tumor tissue for cancer genomic profiling tests. Pathology International (2021), which has been published in final form at https://doi.org/10.1111/pin.13086. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This fulltext is available in March 2022.\|
発行日	2021-03-03
出版物タイトル	Pathology International
巻	71巻
出版者	Wiley
開始ページ	360
終了ページ	364
ISSN	1320-5463
NCID	AA10984364
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	33657250
DOI	10.1111/pin.13086
Web of Science KeyUT	000624843200001
関連URL	isVersionOf https://doi.org/10.1111/pin.13086

Lung stereotactic body radiation therapy for elderly patients aged >= 80 years with pathologically proven early-stage non-small cell lung cancer: a retrospective cohort study

フルテキストURL	fulltext.pdf
著者	Watanabe, Kenta\| Katsui, Kuniaki\| Sugiyama, Soichiro\| Yoshio, Kotaro\| Kuroda, Masahiro\| Hiraki, Takao\| Kiura, Katsuyuki\| Maeda, Yoshinobu\| Toyooka, Shinichi\| Kanazawa, Susumu\|
キーワード	Clinical pathology Elderly Non-small cell lung carcinoma Radiosurgery Stereotactic body radiation therapy
発行日	2021-02-23
出版物タイトル	Radiation Oncology
巻	16巻
号	1号
出版者	BMC
開始ページ	39
ISSN	1748-717X
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2021.
論文のバージョン	publisher
PubMed ID	33622369
DOI	10.1186/s13014-021-01769-7
Web of Science KeyUT	000623175000001
関連URL	isVersionOf https://doi.org/10.1186/s13014-021-01769-7

Protocol for a multicentre, prospective, cohort study to investigate patient satisfaction and quality of life after immediate breast reconstruction in Japan: the SAQLA study

フルテキストURL	fulltext.pdf
著者	Saiga, Miho\| Hosoya, Yuko\| Utsunomiya, Hiroki\| Kuramoto, Yukiko\| Watanabe, Satoko\| Tomita, Koichi\| Aihara, Yukiko\| Muto, Mayu\| Hikosaka, Makoto\| Kawaguchi, Takashi\| Miyaji, Tempei\| Yamaguchi, Takuhiro\| Zenda, Sadamoto\| Goto, Aya\| Sakuraba, Minoru\| Kusano, Taro\| Miyabe, Kenta\| Kuroki, Tomoaki\| Yano, Tomoyuki\| Taminato, Mifue\| Sekido, Mitsuru\| Tsunoda, Yui\| Satake, Toshihiko\| Doihara, Hiroyoshi\| Kimata, Yoshihiro\|
キーワード	plastic & reconstructive surgery breast surgery breast tumours
発行日	2021
出版物タイトル	BMJ Open
巻	11巻
号	2号
出版者	BMJ Publishing Group
開始ページ	e042099
ISSN	2044-6055
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© Author(s) (or their employer(s)) 2021.
論文のバージョン	publisher
PubMed ID	33589456
DOI	10.1136/bmjopen-2020-042099
Web of Science KeyUT	000620632000002
関連URL	isVersionOf https://doi.org/10.1136/bmjopen-2020-042099

The prognostic impact of sarcopenia on elderly patients undergoing pulmonary resection for non-small cell lung cancer

フルテキストURL	fulltext.pdf Figures.pptx Tables.pdf Supplementary figure 1.pptx Supplementary_tables.pdf
著者	Miura, Akihiro\| Yamamoto, Hiromasa\| Sato, Hiroki\| Tomioka, Yasuaki\| Shiotani, Toshio\| Suzawa, Ken\| Miyoshi, Kentaroh\| Otani, Shinji\| Okazaki, Mikio\| Sugimoto, Seiichiro\| Yamane, Masaomi\| Toyooka, Shinichi\|
キーワード	Sarcopenia Elderly patient Non-small cell lung cancer Pulmonary resection
備考	This is a post-peer-review, pre-copyedit version of an article published in Surgery Today. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00595-020-02221-1.\|
発行日	2021-2-9
出版物タイトル	Surgery Today
巻	51巻
出版者	Springer
開始ページ	1203
終了ページ	1211
ISSN	0941-1291
NCID	AA10824685
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	33559731
DOI	10.1007/s00595-020-02221-1
Web of Science KeyUT	000616430800002
関連URL	isVersionOf https://doi.org/10.1007/s00595-020-02221-1

Investigation of Factors Affecting Early Quality of Life of Patients after Breast Cancer Surgery

フルテキストURL	fulltext.pdf
著者	Akezaki, Yoshiteru\| Nakata, Eiji\| Kikuuchi, Masato\| Tominaga, Ritsuko\| Kurokawa, Hideaki\| Okamoto, Masaki\| Hamada, Makiko\| Aogi, Kenjiro\| Ohsumi, Shozo\| Sugihara, Shinsuke\|
キーワード	quality of life breast cancer neoadjuvant chemotherapy postoperative chemotherapy postoperative radiotherapy
発行日	2021-02-16
出版物タイトル	Healthcare
巻	9巻
号	2号
出版者	MDPI
開始ページ	213
ISSN	2227-9032
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 by the authors.
論文のバージョン	publisher
PubMed ID	33669376
DOI	10.3390/healthcare9020213
Web of Science KeyUT	000622553100001
関連URL	isVersionOf https://doi.org/10.3390/healthcare9020213

The prognostic nutritional index is correlated negatively with the lung allocation score and predicts survival after both cadaveric and living-donor lobar lung transplantation

フルテキストURL	fulltext.pdf
著者	Yamamoto, Haruchika\| Sugimoto, Seiichiro\| Soh, Junichi\| Shiotani, Toshio\| Miyoshi, Kentaroh\| Otani, Shinji\| Okazaki, Mikio\| Yamane, Masaomi\| Toyooka, Shinichi\|
キーワード	Prognostic nutrition index Lung allocation score Lung transplantation Living-donor lobar lung transplantation Outcome
備考	This is a post-peer-review, pre-copyedit version of an article published in Surgery Today. The final authenticated version is available online at: https://doi.org/10.1007/s00595-021-02244-2.\|
発行日	2021-2-13
出版物タイトル	Surgery Today
巻	51巻
出版者	Springer
開始ページ	1610
終了ページ	1618
ISSN	0941-1291
NCID	AA10824685
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	33582840
DOI	10.1007/s00595-021-02244-2
Web of Science KeyUT	000617830200001
関連URL	isVersionOf https://doi.org/10.1007/s00595-021-02244-2

Successful Bronchoscopic Treatment for Postoperative Bronchopleural Fistula Using N-butyl-2-cyanoacrylate (NBCA): Report of a Post-completion Pneumonectomy Case with a History of Induction Chemoradiotherapy Followed by Bilobectomy for Advanced Lung Cancer

JaLCDOI	10.18926/AMO/61440
フルテキストURL	75_1_91.pdf
著者	Shiotania, Toshio\| Yamamoto, Hiromasa\| Katsube, Riko\| Tomioka, Yasuaki\| Suzawa, Ken\| Miyoshi, Kentaroh\| Otani, Shinji\| Okazaki, Mikio\| Sugimoto, Seiichiro\| Sohb, Junichi\| Yamane, Masaomi\| Toyooka, Shinichi\|
抄録	Bronchopleural fistula (BPF) is a severe complication following lung resection. We present the case of a patient with a history of advanced lung cancer, who had undergone induction chemoradiotherapy followed by right middle and lower lobectomy, and who developed BPF after completion right pneumonectomy. Although we had covered the bronchial stump with an omental pedicled flap, BPF was found on postoperative day 19. We covered the fistula with n-butyl-2-cyanoacrylate (NBCA) using bronchoscopy. Although we had to repeat the NBCA treatment, we ultimately cured the patient’s BPF and no recurrence was observed up to 15.2 months after surgery.
キーワード	bronchopleural fistula pneumonectomy induction chemoradiotherapy n-butyl-2-cyanoacrylate (NBCA) omental pedicled flap
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-02
巻	75巻
号	1号
出版者	Okayama University Medical School
開始ページ	91
終了ページ	94
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33649619

Long-term Follow-up of Living-Donor Kidney Transplantation after Cadaveric Lung Transplantation

JaLCDOI	10.18926/AMO/61439
フルテキストURL	75_1_87.pdf
著者	Shiotani, Toshio\| Sugimoto, Seiichiro\| Araki, Kota\| Tomioka, Yasuaki\| Miyoshi, Kentaroh\| Otani, Shinji\| Yamane, Masaomi\| Toyooka, Shinichi\|
抄録	Although chronic kidney disease (CKD) commonly develops after lung transplantation (LT), living-donor kid-ney transplantation (LDKT) for CKD after LT is known to provide favorable outcomes. We describe the long-term follow-up findings of a patient who underwent LDKT after bilateral cadaveric LT. A 37-year-old male underwent LDKT for CKD 18 years after receiving bilateral cadaveric LT. He developed chronic lung allograft dysfunction (CLAD) 20 years after the LT; however, at 26 years after the initial LT, he is still alive with no pro-gression of CLAD or CKD. KT could be a viable option for CKD even after LT in Japan.
キーワード	lung transplantation kidney transplantation chronic kidney disease non-tuberculous mycobacterial infection chronic lung allograft dysfunction
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-02
巻	75巻
号	1号
出版者	Okayama University Medical School
開始ページ	87
終了ページ	89
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33649618

The Optimal Prepregnancy Body Mass Index for Lactation in Japanese Women with Neonatal Separation as Analyzed by a Differential Equation

JaLCDOI	10.18926/ATM/61436
フルテキストURL	75_1_63.pdf
著者	Tada, Katsuhiko\| Miyagi, Yasunari\| Nakamura, Kazue\| Yorozu, Moe\| Fukushima, Emi\| Kumazawa, Kazumasa\| Nakamura, Makoto\| Kageyama, Misao\|
抄録	We used a differential equation to identify the biological relationship between the maternal prepregnancy body mass index (BMI) and lactation on postpartum day 4 in Japanese women with neonatal separation. This retro-spective observational study included 252 mothers (135 primiparas, 117 multiparas) whose singleton neonates were admitted to a neonatal ICU. We formulated hypotheses based on breast anatomy to analyze the relation-ship between the expressed milk obtained on postpartum day 4 and the maternal prepregnancy BMI with the following differential equation: y’(x) = k y(x)/x, where k is the constant, x is the prepregnancy BMI, and y is the expressed milk volume. The formula was then obtained as y(x) = axk, where a is the constant. The Akaike information criterion (AIC) was used to estimate the regression equation with the maximum likelihood for primiparas and multiparas. The best criteria for BMI determined by the AIC were 20.89 kg/m2 in primiparas and 20.19 kg/m2 in multiparas. These were the optimal BMI values for lactation, coinciding with the median prepregnancy BMI in the study population (20.78 kg/m2 in primiparas and 20.06 kg/m2 in multiparas). The formula based on biomathematics might help establish the biological relationship between prepregnancy BMI and breastmilk volume.
キーワード	biomathematics body mass index expressed milk lactation
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-02
巻	75巻
号	1号
出版者	Okayama University Medical School
開始ページ	63
終了ページ	69
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	33649615