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フルテキストURL fulltext.pdf
著者 Hassan, Ghmkin| Afify, Said M.| Zahra, Maram H.| Nawara, Hend M.| Kumon, Kazuki| Iwasaki, Yoshiaki| Salomon, David S.| Seno, Akimasa| Seno, Masaharu|
キーワード Cancer stem cells Human iPSCs Signal pathway inhibitors Tumor initiation
備考 The version of record of this article, first published in Cytotechnology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10616-023-00575-1|
発行日 2023-04-01
出版物タイトル Cytotechnology
75巻
3号
出版者 Springer Science and Business Media LLC
開始ページ 243
終了ページ 253
ISSN 0920-9069
NCID AA10678299
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2023
論文のバージョン publisher
PubMed ID 37181678
DOI 10.1007/s10616-023-00575-1
Web of Science KeyUT 000961388400001
関連URL isVersionOf https://doi.org/10.1007/s10616-023-00575-1
フルテキストURL fulltext.pdf
著者 Takahashi, Tetta| Tomonobu, Nahoko| Kinoshita, Rie| Yamamoto, Ken-Ichi| Murata, Hitoshi| Komalasari, Ni Luh Gede Yoni| Chen, Youyi| Jiang, Fan| Gohara, Yuma| Ochi, Toshiki| Ruma, I. Made Winarsa| Sumardika, I. Wayan| Zhou, Jin| Honjo, Tomoko| Sakaguchi, Yoshihiko| Yamauchi, Akira| Kuribayashi, Futoshi| Kondo, Eisaku| Inoue, Yusuke| Futami, Junichiro| Toyooka, Shinichi| Zamami, Yoshito| Sakaguchi, Masakiyo|
キーワード breast cancer lysyl oxidase annexin A2 S100A11 plasmin cancer microenvironment
発行日 2024-03-26
出版物タイトル Frontiers in Oncology
14巻
出版者 Frontiers Media
開始ページ 1371342
ISSN 2234-943X
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 Takahashi, Tomonobu, Kinoshita, Yamamoto, Murata, Komalasari, Chen, Jiang, Gohara, Ochi, Ruma, Sumardika, Zhou, Honjo, Sakaguchi, Yamauchi, Kuribayashi, Kondo, Inoue, Futami, Toyooka, Zamami and Sakaguchi.
論文のバージョン publisher
PubMed ID 38595825
DOI 10.3389/fonc.2024.1371342
Web of Science KeyUT 001198366100001
関連URL isVersionOf https://doi.org/10.3389/fonc.2024.1371342
フルテキストURL fulltext.pdf
著者 Wu, Chongyang| Tanaka, Ryota| Fujiyoshi, Kyohei| Akaji, Yasuaki| Hirobe, Muneto| Miki, Naoko| Li, Juan| Sakamoto, Keiji| Gao, Jian|
キーワード bamboo sasa beech forest phenological gap canopy understory plant plant morphology plastically leaf phenology
発行日 2024-03-04
出版物タイトル Plants
13巻
5号
出版者 MDPI
開始ページ 719
ISSN 2223-7747
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 by the authors.
論文のバージョン publisher
PubMed ID 38475565
DOI 10.3390/plants13050719
Web of Science KeyUT 001183421800001
関連URL isVersionOf https://doi.org/10.3390/plants13050719
フルテキストURL fulltext.pdf
著者 Zhao, Songhao| Shen, Lili| Li, Xiaoyi| Tao, Qiushuang| Li, Zhenhua| Xu, Caizhe| Zhou, Cuicui| Yang, Yanyan| Sang, Min| Han, Guangye| Yu, Long-Jiang| Kuang, Tingyun| Shen, Jian-Ren| Wang, Wenda|
備考 The version of record of this article, first published in Nature Communications, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41467-023-44055-8|
発行日 2023-12-09
出版物タイトル Nature Communications
14巻
1号
出版者 Nature Portfolio
開始ページ 8164
ISSN 2041-1723
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2023
論文のバージョン publisher
PubMed ID 38071196
DOI 10.1038/s41467-023-44055-8
Web of Science KeyUT 001118826100025
関連URL isVersionOf https://doi.org/10.1038/s41467-023-44055-8
JaLCDOI 10.18926/AMO/66673
フルテキストURL 78_1_071.pdf
著者 Kaneda, Daisuke| Nishida, Keiichiro| Nasu, Yoshihisa| Nakahara, Ryuichi| Harada, Ryozo| Hotta, Yoshifumi| Naniwa, Shuichi| Ozaki, Toshifumi|
抄録 We retrospectively investigated the mid-term outcomes of arthroplasty using the AVANTA silicone implant for thumb metacarpophalangeal (MCP) joints with boutonniere deformity in patients with rheumatoid arthritis (RA). This study involved 36 thumbs of 33 RA patients with a mean follow-up period of 5.1 years (range, 2.0-13.3). Postoperatively, the mean extension was significantly increased and the mean flexion was significantly decreased (p<0.001, p<0.001, respectively), resulting in the mean arc of range of motion (ROM) shifting in the direction of extension after surgery. Implant fracture was observed in 10 thumbs (28%), and 4 of these (11%) underwent revision surgery. The survivorship with implant fracture and revision surgery as endpoints were 73.4% and 91.8% at 5 years, respectively. The preoperative arc of ROM and the postoperative flexion range of the implant-fracture group were significantly greater than those in the no-implant-fracture group (p=0.039, 0.034, respectively). These results suggest the importance of patient education and careful rehabilitation to prevent excessive flexion. Overall, the AVANTA silicone implant showed a relatively high rate of implant fracture at our institute.
キーワード AVANTA silicone implant boutonniere deformity implant fracture thumb metacarpophalangeal joint arthroplasty rheumatoid arthritis
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2024-02
78巻
1号
出版者 Okayama University Medical School
開始ページ 71
終了ページ 78
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 38419317
Web of Science KeyUT 001203658200011
フルテキストURL fulltext20240221-01.pdf
著者 Iijima, Yuta| Miki, Ryohei| Fujimura, Masatake| Oyadomari, Seiichi| Uehara, Takashi|
キーワード Methylmercury Neuronal cell death Apoptosis CHOP Knockout mouse
発行日 2024
出版物タイトル The Journal of Toxicological Sciences
49巻
2号
出版者 Japanese Society of Toxicology
開始ページ 55
終了ページ 60
ISSN 0388-1350
NCID AN00002808
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2024 The Japanese Society of Toxicology
論文のバージョン publisher
PubMed ID 38296529
DOI 10.2131/jts.49.55
Web of Science KeyUT 001157348600004
関連URL isVersionOf https://doi.org/10.2131/jts.49.55
フルテキストURL fulltext.pdf
著者 Iwamuro, Masaya| Takenaka, Ryuta| Toyokawa, Tatsuya| Kita, Masahide| Tsuzuki, Takao| Yoshioka, Masao| Gotoda, Tatsuhiro| Okanoue, Shotaro| Matsubara, Minoru| Sakaguchi, Chihiro| Otsuka, Motoyuki|
備考 The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-52633-z|
発行日 2024-01-25
出版物タイトル Scientific Reports
14巻
1号
出版者 Nature Portfolio
開始ページ 2202
ISSN 2045-2322
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2024
論文のバージョン publisher
PubMed ID 38273039
DOI 10.1038/s41598-024-52633-z
Web of Science KeyUT 001151714000020
関連URL isVersionOf https://doi.org/10.1038/s41598-024-52633-z
フルテキストURL fulltext20240206-03.pdf
著者 Ishii, Tomoya| Tsuchida, Natsuki| Hemelda, Niarsi Merry| Saito, Kirara| Bao, Jiyuan| Watanabe, Megumi| Toyoda, Atsushi| Matsubara, Takehiro| Sato, Mayuko| Toyooka, Kiminori| Ishihama, Nobuaki| Shirasu, Ken| Matsui, Hidenori| Toyoda, Kazuhiro| Ichinose, Yuki| Hayashi, Tetsuya| Kawaguchi, Akira| Noutoshi, Yoshiteru|
キーワード tailocin phage tail-like bacteriocin Allorhizobium vitris Alphaproteobacteria biocontrol crown gall disease interbacterial antagonism grapevine
発行日 2024-01-18
出版物タイトル The ISME Journal
18巻
1号
出版者 Oxford University Press (OUP)
開始ページ 1
終了ページ 12
ISSN 1751-7362
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) [2024].
論文のバージョン publisher
DOI 10.1093/ismejo/wrad003
Web of Science KeyUT 001145343000001
関連URL isVersionOf https://doi.org/10.1093/ismejo/wrad003
フルテキストURL fulltext.pdf
著者 Hashimoto, Mana| Takahashi, Haruka| Tabata-Okubo, Kaori| Nagaoka, Noriyuki| Tokunaga, Kazuaki| Matsumori, Haruka| Ishihara, Yoshihito| Kaku, Masaru| Iimura, Tadahiro| Hara, Toru| Kamioka, Hiroshi|
備考 The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-48786-y|
発行日 2023-12-12
出版物タイトル Scientific Reports
13巻
1号
出版者 Nature Portfolio
開始ページ 22028
ISSN 2045-2322
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2023
論文のバージョン publisher
PubMed ID 38086873
DOI 10.1038/s41598-023-48786-y
Web of Science KeyUT 001126179100035
関連URL isVersionOf https://doi.org/10.1038/s41598-023-48786-y
フルテキストURL fulltext20240117-01.pdf fig1_20240117-01.pdf fig2_20240117-01.pdf fig3_20240117-01.pdf
著者 Koyama, Toshihiro| Iinuma, Shunya| Yamamoto, Michio| Niimura, Takahiro| Osaki, Yuka| Nishimura, Sayoko| Harada, Ko| Zamami, Yoshito| Hagiya, Hideharu|
備考 This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s40264-023-01387-0| This fulltext file will be available in Dec. 2024.|
発行日 2023-12-22
出版物タイトル Drug Safety
47巻
3号
出版者 Springer Science and Business Media LLC
開始ページ 237
終了ページ 249
ISSN 0114-5916
NCID AA10748827
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 Copyright © 2023, The Author(s), under exclusive licence to Springer Nature Switzerland AG
論文のバージョン author
PubMed ID 38133735
DOI 10.1007/s40264-023-01387-0
Web of Science KeyUT 001132965700001
関連URL isVersionOf https://doi.org/10.1007/s40264-023-01387-0
フルテキストURL fulltext20240116-01.pdf
著者 Himi, Eiko| Kurihara-Yonemoto, Shiho| Abe, Fumitaka| Takahashi, Hidekazu| Tanaka, Keisuke| Matsuura, Takakazu| Maekawa, Masahiko| Sasaki, Takuji| Rikiishi, Kazuhide|
キーワード Lipid transfer protein Pre-harvest sprouting Seed dormancy Seed germination Tamyb10 Wheat
備考 The version of record of this article, first published in [Journal name], is available online at Publisher’s website: http://dx.doi.org/10.1007/s10681-023-03265-3|
発行日 2024-01-08
出版物タイトル Euphytica
220巻
2号
出版者 Springer Science and Business Media LLC
開始ページ 16
ISSN 0014-2336
NCID AA00639246
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2024
論文のバージョン publisher
DOI 10.1007/s10681-023-03265-3
Web of Science KeyUT 001137699100001
関連URL isVersionOf https://doi.org/10.1007/s10681-023-03265-3
フルテキストURL fulltext.pdf
著者 Kato, Yusuke| Kuroda, Hiroshi| Ozawa, Shin-Ichiro| Saito, Keisuke| Dogra, Vivek| Scholz, Martin| Zhang, Guoxian| de Vitry, Catherine| Ishikita, Hiroshi| Kim, Chanhong| Hippler, Michael| Takahashi, Yuichiro| Sakamoto, Wataru|
キーワード post-translational modification Arabidopsis thaliana protein degradation photosystem II photo-oxidative damage tryptophan oxidation Chlamydomonas reinhardtii
発行日 2023-11-21
出版物タイトル eLife
12巻
出版者 eLife Sciences Publications
開始ページ RP88822
ISSN 2050-084X
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © Kato, Kuroda, Ozawa et al.
論文のバージョン publisher
PubMed ID 37986577
DOI 10.7554/eLife.88822
Web of Science KeyUT 001134641800001
関連URL isVersionOf https://doi.org/10.7554/eLife.88822
フルテキストURL fulltext20240226-02.pdf
著者 Ikeda, Hideki| Nagasaki, Joji| Shimizu, Daiki| Katsuya, Yuki| Horinouchi, Hidehito| Hosomi, Yukio| Tanji, Etsuko| Iwata, Takekazu| Itami, Makiko| Kawazu, Masahito| Ohe, Yuichiro| Suzuki, Takuji| Togashi, Yosuke|
キーワード Thymic epithelial tumor Cancer immunotherapy CD80/CD86 MHC Memory precursor effector T cell
発行日 2023-10
出版物タイトル JTO Clinical and Research Reports
4巻
10号
出版者 Elsevier
開始ページ 100573
ISSN 2666-3643
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 The Authors.
論文のバージョン publisher
PubMed ID 37799325
DOI 10.1016/j.jtocrr.2023.100573
Web of Science KeyUT 001161095400001
関連URL isVersionOf https://doi.org/10.1016/j.jtocrr.2023.100573
JaLCDOI 10.18926/66188
フルテキストURL jdc_003_001.pdf
著者 TSURI, Masao| AOO, Ken|
抄録 Holistic well-being has rapidly developed in the 21st century as a policy measurement tool. Nevertheless, there continue to be some gaps in the literature regarding the interrelation between subjective well-being and other factors, and, regarding disaggregation of the well-being status within a country, by age group, gender, and community. This study first illustrates how the concept of well-being developed from a philosophical and psychological conception of “happiness” to being measured by multidimensional tools that measure the impact of policy and the progress of society, such as OECD’s Better Life Index, UK’s National Well-being Measurement, and Japan’s Well-being Survey and Quality of Life. Subsequently, it analyzes the relationships between subjective well-being and objective variables by comparing the country, regional, and individual datasets. It found that some indicators, such as social relationships, have asymmetric effects on life satisfaction depending on the income level or threshold. In other words, if the income is less than a certain level, the effects of some indicators on life satisfaction are complementary to income, while if the income is above that level, the effects are substitutional. Finally, it estimates these effects and confirms them statistically by using the OECD Regional Statistics. Regarding the relationship between social connection and self-evaluation of life satisfaction rated on a 10-point Likert scale, the base score in the estimation is approximately 5.1 points higher in the lowest quartile group of income. However, the substitution is lower than that of the other groups by approximately -0.061. The coefficient of social connection for the other groups was approximately 0.059, and the lowest group had almost zero coefficients for substitution.
キーワード well-being household income social connection OECD Regional Statistics
Amo Type 論文 (Research article)
出版物タイトル 文明動態学
発行日 2024-03-25
3巻
出版者 岡山大学文明動態学研究所
開始ページ 1
終了ページ 20
ISSN 2436-8326
資料タイプ 学術雑誌論文
言語 英語
著作権者 © 2024 by RIDC
論文のバージョン publisher
JaLCDOI 10.18926/AMO/66152
フルテキストURL 77_6_607.pdf
著者 Tani, Yasunari| Kashima, Saori| Mitsuhashi, Toshiharu| Suzuki, Etsuji| Takao, Soshi| Yorifuji, Takashi|
抄録 Many studies have shown an association between long-term exposure to particulate matter having an aerodynamic diameter of 2.5 μm or less (PM2.5) and diabetes mellitus (DM), but few studies have focused on Asian subjects. We thus examined the association between long-term exposure to PM2.5 and DM prevalence in Okayama City, Japan. We included 76,591 participants who had received basic health checkups in 2006 and 2007. We assigned the census-level modeled PM2.5 data from 2006 and 2007 to each participant and defined DM using treatment status and the blood testing. PM2.5 was associated with DM prevalence, and the prevalence ratio (95% confidence interval) was 1.10 (1.00-1.20) following each interquartile range increase (2.1 μg/m3) in PM2.5. This finding is consistent with previous results and suggests that long-term exposure to PM2.5 is associated with an increased prevalence of DM in Okayama City, Japan, where the PM2.5 level is lower than in other cities in Asian countries.
キーワード air pollution diabetes mellitus epidemiology glycosylated hemoglobin particulate matter
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-12
77巻
6号
出版者 Okayama University Medical School
開始ページ 607
終了ページ 612
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 38145934
Web of Science KeyUT 001164631200005
JaLCDOI 10.18926/AMO/66149
フルテキストURL 77_6_577.pdf
著者 Liu, Siyu| Athurupana, Rukmali| Han, Hongmei| Yang, Titi| Nakatsuka, Mikiya|
抄録 Bereavement care is conducted to meet the emotional needs of grieving couples who are devastated by the experience of a miscarriage or stillbirth. From January to April 2022, we distributed a questionnaire that assessed the knowledge and attitudes of Japanese nursing staff (nurses and midwives) in Japan’s Chugoku-Shikoku region toward bereavement care for couples with miscarriage/stillbirth. The 370 survey respondents’ answers revealed that the nursing staff’s knowledge regarding recurrent pregnancy loss and subsequent bereavement care was insufficient. About 41.1% and 64.1% of the respondents had received school and on-the-job education in bereavement care, respectively, and 79.2% expressed willingness to provide such care. Our analyses revealed that the following factors were associated with the nursing staff’s knowledge level: parent status, age, reproductive history, midwifery license, work experience and environment, and on-the-job education. The following were correlated with the staff’s willingness to provide bereavement care: work environment, midwifery license, bereavement care knowledge, and on-the-job education. Together our findings indicate that education plays a significant role in equipping caregivers to provide effective bereavement care for couples who have experienced a miscarriage or stillbirth.
キーワード midwife nurse miscarriage bereavement knowledge
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2023-12
77巻
6号
出版者 Okayama University Medical School
開始ページ 577
終了ページ 587
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2023 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 38145931
Web of Science KeyUT 001164631200002
フルテキストURL fulltext.pdf
著者 Watari, Shogo| Katayama, Satoshi| Shiraishi, Hiromasa| Tokunaga, Moto| Kubota, Risa| Kusumi, Norihiro| Ichikawa, Takaharu| Tsushima, Tomoyasu| Kobayashi, Yasuyuki| Bekku, Kensuke| Araki, Motoo|
キーワード Geriatric Nutritional Risk Index Immune checkpoint inhibitor Renal cell carcinoma Prognosis
備考 The version of record of this article, first published in Discover Oncology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s12672-023-00816-x|
発行日 2023-11-16
出版物タイトル Discover Oncology
14巻
1号
出版者 Springer
開始ページ 204
ISSN 2730-6011
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2023
論文のバージョン publisher
PubMed ID 37968545
DOI 10.1007/s12672-023-00816-x
Web of Science KeyUT 001103962100001
関連URL isVersionOf https://doi.org/10.1007/s12672-023-00816-x
フルテキストURL fulltext.pdf
著者 Ichihara, Eiki| Hasegawa, Kou| Kudo, Kenichiro| Tanimoto, Yasushi| Nouso, Kazuhiro| Oda, Naohiro| Mitsumune, Sho| Yamada, Haruto| Takata, Ichiro| Hagiya, Hideharu| Mitsuhashi, Toshiharu| Taniguchi, Akihiko| Toyooka, Shinichi| Tsukahara, Kohei| Aokage, Toshiyuki| Tsukahara, Hirokazu| Kiura, Katsuyuki| Maeda, Yoshinobu|
発行日 2023-10-26
出版物タイトル PLoS ONE
18巻
10号
出版者 Public Library of Science
開始ページ e0287501
ISSN 1932-6203
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 Ichihara et al.
論文のバージョン publisher
PubMed ID 37883347
DOI 10.1371/journal.pone.0287501
Web of Science KeyUT 001094123400028
関連URL isVersionOf https://doi.org/10.1371/journal.pone.0287501
フルテキストURL fulltext.pdf
著者 Liu, Shanshan| Levinson, Ronnen| Narumi, Daisuke|
キーワード urban heat island densely built area energy saving indoor thermal comfort heat countermeasure
発行日 2023-10-16
出版物タイトル Atmosphere
14巻
10号
出版者 MDPI
開始ページ 1566
ISSN 2073-4433
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 by the authors.
論文のバージョン publisher
DOI 10.3390/atmos14101566
Web of Science KeyUT 001090009400001
関連URL isVersionOf https://doi.org/10.3390/atmos14101566
フルテキストURL fulltext20231110-01.pdf
著者 Dansako, Hiromichi| Ikeda, Masanori| Ariumi, Yasuo| Togashi, Yosuke| Kato, Nobuyuki|
キーワード double-stranded RNA hepatitis C virus innate immunity RIG-I-like receptor RNA virus
備考 This is the accepted version of the following article: Dansako, H., Ikeda, M., Ariumi, Y., Togashi, Y. and Kato, N. (2024), Hepatitis C virus NS5B triggers an MDA5-mediated innate immune response by producing dsRNA without the replication of viral genomes. FEBS J, 291: 1119-1130. https://doi.org/10.1111/febs.16980, which has been published in final form at https://doi.org/10.1111/febs.16980| This fulltext file will be available in Oct. 2024.|
発行日 2023-10-20
出版物タイトル The FEBS Journal
291巻
6号
出版者 Wiley
開始ページ 1119
終了ページ 1130
ISSN 1742-464X
NCID AA11998513
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 Federation of European Biochemical Societies.
論文のバージョン author
PubMed ID 37863517
DOI 10.1111/febs.16980
Web of Science KeyUT 001091349500001
関連URL isVersionOf https://doi.org/10.1111/febs.16980