検索結果 3115 件
| 著者 | Takasaka, Kenji| Iwai, Masako| Umena, Yasufumi| Kawakami, Keisuke| Ohmori, Yukari| Ikeuchi, Masahiko| Takahashi, Yuichiro| Kamiya, Nobuo| Shen, Jian-Ren| |
|---|---|
| 発行日 | 2010-02 |
| 出版物タイトル | Biochimica et Biophysica Acta (BBA) - Bioenergetics |
| 巻 | 1797巻 |
| 号 | 2号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Shen, Jian-Ren| Kawakami, Keisuke| Koike, Hiroyuki| |
|---|---|
| 発行日 | 2011 |
| 出版物タイトル | Methods in Molecular Biology |
| 巻 | 684巻 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Nagao, Ryo| Moriguchi, Akira| Tomo, Tatsuya| Niikura, Ayako| Nakajima, Saori| Suzuki, Takehiro| Okumura, Akinori| Iwai, Masako| Shen, Jian-Ren| Ikeuchi, Masahiko| Enami, Isao| |
|---|---|
| 発行日 | 2010-09-17 |
| 出版物タイトル | The Journal of Biological Chemistry |
| 巻 | 285巻 |
| 号 | 38号 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | Enami, Isao| Adachi, Hideyuki| Shen, Jian-Ren| |
|---|---|
| 発行日 | 2010 |
| 出版物タイトル | Red Algae in the Genomic Age |
| 巻 | 13巻 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/AMO/48670 |
|---|---|
| フルテキストURL | 66_4_307.pdf |
| 著者 | Iida, Tadayuki| Chikamura, Chiho| Ishikawa, Hiroaki| Aoi, Satomi| Ikeda, Hiromi| Harada, Toshihide| Katada, Kazuhiro| Ishizaki, Fumiko| Yatsuya, Hiroshi| Ono, Yuichiro| |
| 抄録 | Currently, 26% of Japanese women in their twenties are under weight, and therefore at risk of developing various metabolic abnormalities due to an inadequate nutrient intake, which in turn affects the acquisition of a peak bone mineral density (BMD). In this study, we aimed to clarify the effects of menstrual cycle-related changes in body weight and bone metabolic marker levels on the BMD changes. The subjects were 42 women (19.6±0.8 years). The levels of osteocalcin (OC), BAP, s-NTx, u-DPD, and E2 in the menstrual and ovulatory phases were measured. The associations between dependent variables (BMD changes/year in the lumbar spine, femur, femoral neck) and explanatory variables (body weight changes/year, the levels of OC, BAP, s-NTx, u-DPD) were evaluated using multiple regression analysis. Analysis of the correlations between the changes in bone metabolic markers and changes in BMD showed a correlation between the OC level in the menstrual phase and changes in the BMD of the entire femur, suggesting that a high OC level protects against BMD reduction, probably by promoting osteoblast activity, and that bone formation activity suppresses the decrease in BMD. These results suggest that, to predict BMD changes from bone metabolic markers in young women, it is necessary to measure OC levels in the menstrual phase. |
| キーワード | BMD bone metabolic marker menstrual cycle |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2012-08 |
| 巻 | 66巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 307 |
| 終了ページ | 315 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2012 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 22918203 |
| Web of Science KeyUT | 000307918900003 |
| JaLCDOI | 10.18926/AMO/48566 |
|---|---|
| フルテキストURL | 66_3_263.pdf |
| 著者 | Sasaki, Takanori| Kuroda, Masahiro| Katashima, Kazunori| Ashida, Masakazu| Matsuzaki, Hidenobu| Asaumi, Junichi| Murakami, Jun| Ohno, Seiichiro| Kato, Hirokazu| Kanazawa, Susumu| |
| 抄録 | The roles of cell density, extracellular space, intracellular factors, and apoptosis induced by the molecularly targeted drug rituximab on the apparent diffusion coefficient (ADC) values were investigated using bio-phantoms. In these bio-phantoms, Ramos cells (a human Burkittｾs lymphoma cell line) were encapsulated in gellan gum. The ADC values decreased linearly with the increase in cell density, and declined steeply when the extracellular space became less than 4 μm. The analysis of ADC values after destruction of the cellular membrane by sonication indicated that approximately 65% of the ADC values of normal cells originate from the cell structures made of membranes and that the remaining 35% originate from intracellular components. Microparticles, defined as particles smaller than the normal cells, increased in number after rituximab treatments, migrated to the extracellular space and significantly decreased the ADC values of bio-phantoms during apoptosis. An in vitro study using bio-phantoms was conducted to quantitatively clarify the roles of cellular factors and of extracellular space in determining the ADC values yielded by tumor cells and the mechanism by which apoptosis changes those values. |
| キーワード | apparent diffusion coefficient value cell density extracellular space bio-phantom |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2012-06 |
| 巻 | 66巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 263 |
| 終了ページ | 270 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2012 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 22729107 |
| Web of Science KeyUT | 000305669700010 |
| JaLCDOI | 10.18926/AMO/48559 |
|---|---|
| フルテキストURL | 66_3_203.pdf |
| 著者 | Ohno, Seiichiro| Harimoto, Takashi| Hirosue, Miyuki| Miyai, Masahiro| Hattori, Kengo| Kuroda, Masahiro| Kanazawa, Susumu| Inamura, Keiji| Kato, Hirokazu| |
| 抄録 | Magnetic resonance imaging (MRI) visualization of metallic stent lumens is possible if the stent structure counteracts eddy currents in the lumen induced by the radio frequency magnetic field, B1. To examine the effectiveness of various stent designs in counteracting eddy currents, we anchored eight copper stent models and 2 commercially available nickel-titanium alloy (Nitinol) stents in a gel phantom, perpendicular or parallel to the direction of B1. A mesh stent lumen showed hypointensity irrespective of its alignment relative to B1. A solenoid stent lumen showed hypointensity with the stent axis parallel to B1, but it had the same signal intensity as outside the lumen when perpendicular to B1. A Moebius stent lumen showed no signal reduction, irrespective of alignment relative to B1. Lumens of the commercially available stents showed hypointensity regardless of alignment relative to B1. Computer simulation revealed that the signal intensities of the stents corresponded to magnetic flux densities of B1 in the stents, which are modified by the structure of the stent. While in vivo MRI viewing of a Moebius stent lumen is likely possible regardless of axis alignment, inherent structural weakness may be problematic. As a more practical choice, the solenoid stent is easier to manufacture and generates no hypointensive signal when the axis is parallel to B0. |
| キーワード | MRI visualization of stent lumen solenoid pattern Moebius pattern direction of B1 |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2012-06 |
| 巻 | 66巻 |
| 号 | 3号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 203 |
| 終了ページ | 211 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2012 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 22729100 |
| Web of Science KeyUT | 000305669700003 |
| 関連URL | http://ousar.lib.okayama-u.ac.jp/metadata/48542 |
| 著者 | 倉林 譲| |
|---|---|
| 発行日 | 2012-04 |
| 出版物タイトル | 岡山実験動物研究会報 |
| 巻 | 28巻 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 深尾 彩加| 中岡 実乃里| 高橋 純夫| 竹内 栄| |
|---|---|
| 発行日 | 2012-04 |
| 出版物タイトル | 岡山実験動物研究会報 |
| 巻 | 28巻 |
| 資料タイプ | 学術雑誌論文 |
| 著者 | 高岡 秀| |
|---|---|
| 発行日 | 2012-04 |
| 出版物タイトル | 岡山実験動物研究会報 |
| 巻 | 28巻 |
| 資料タイプ | その他 |
| 著者 | Yan, He| Li, Lin| Alam, M. Jahangir| Shinoda, Sumio| Miyoshi, Shin-ichi| Shi, Lei| |
|---|---|
| 発行日 | 2010-10-15 |
| 出版物タイトル | International Journal of Food Microbiology |
| 巻 | 143巻 |
| 号 | 3号 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/AMO/48264 |
|---|---|
| フルテキストURL | 66_2_143.pdf.pdf |
| 著者 | Watanabe, Makiko| Ueno, Hiroshi| Suemitsu, Shunsuke| Yokobayashi, Eriko| Matsumoto, Yosuke| Usui, Shinichi| Sujiura, Hiroko| Okamoto, Motoi| |
| 抄録 | Recent studies have demonstrated the important role of immune molecules in the development of neuronal circuitry and synaptic plasticity. We have detected the presence of FcγRllB protein in parvalbumin- containing inhibitory interneurons (PV neurons). In the present study, we examined the appearance of PV neurons in the barrel cortex and the effect of sensory deprivation in FcγRllB-deficient mice (FcγRllB-/-) and wild-type mice. There was no substantial difference in the appearance of PV neurons in the developing barrel cortex between FcγRllB-/- and wild-type mice. Sensory deprivation from immediately after birth (P0) or P7 to P12-P14 induced an increase in PV neurons. In contrast, sensory deprivation from P7 or P14 to P28, but not from P21 to P28, decreased PV neurons in wild-type mice. However, sensory deprivation from P0 or P7 to P12-P14 did not increase PV neurons and sensory deprivation from P7 or P14 to P28 did not decrease or only modestly decreased PV neurons in FcγRllB-/- mice. The results indicate that expression of PV is regulated by sensory experience and the second and third postnatal weeks are a sensitive period for sensory deprivation, and suggest that FcγRllB contributes to sensory experience-regulated expression of PV. |
| キーワード | parvalbumin fast-spiking interneurons FcγRllB barrel cortex sensory deprivation |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2012-04 |
| 巻 | 66巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 143 |
| 終了ページ | 154 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2012 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 22525472 |
| Web of Science KeyUT | 000303175300007 |
| 著者 | 岡山大学環境理工学部| |
|---|---|
| 発行日 | 2012-03 |
| 出版物タイトル | 岡山大学環境理工学部研究報告 |
| 巻 | 17巻 |
| 号 | 1号 |
| 資料タイプ | その他 |
| 著者 | 岡山大学環境理工学部| |
|---|---|
| 発行日 | 2012-03 |
| 出版物タイトル | 岡山大学環境理工学部研究報告 |
| 巻 | 17巻 |
| 号 | 1号 |
| 資料タイプ | その他 |
| 著者 | 岡山大学環境理工学部| |
|---|---|
| 発行日 | 2012-03 |
| 出版物タイトル | 岡山大学環境理工学部研究報告 |
| 巻 | 17巻 |
| 号 | 1号 |
| 資料タイプ | その他 |
| 著者 | 岡山大学環境理工学部| |
|---|---|
| 発行日 | 2012-03 |
| 出版物タイトル | 岡山大学環境理工学部研究報告 |
| 巻 | 17巻 |
| 号 | 1号 |
| 資料タイプ | その他 |
| 著者 | 岡山大学環境理工学部| |
|---|---|
| 発行日 | 2012-03 |
| 出版物タイトル | 岡山大学環境理工学部研究報告 |
| 巻 | 17巻 |
| 号 | 1号 |
| 資料タイプ | その他 |
| JaLCDOI | 10.18926/fest/48239 |
|---|---|
| タイトル（別表記） | The Landscape and Sightseeing of Bittchu-Kokubunji Based on the Viewpoints of Tourists and Local Residents |
| フルテキストURL | fest_017_023_043(1).pdf fest_017_023_043(2).pdf |
| 著者 | 水田 智也| 市南 文一| |
| 抄録 | In this paper, we examined the landscape and sightseeing at Bittchu-Kokubunji in Okayama prefecture carrying out the questionnaire survey to tourists and local residents. Both tourists and local residents estimate that the landscape ofBittchu-Kokubunji is wonderful, and it has several images such as historical, quiet, and old-fashioned, etc. AlthoughBittchu-Kokubunji is one of the famous tourist resorts in Okayama prefecture, there are quite few tourists compared with the degree of notability. Almost all tourists' age was 50 or more. As more active sightseeing activities, the number of times of holding events, such as an announcement of traditional performing arts, lighting of a five-storied pagoda, photograph or a sketching convention, needs to be increased. An attractive tourist resort should be created by the cooperation of local residents and administration. |
| キーワード | Landscape Sightseeing Local residents Bittchu-Kokubunji |
| 出版物タイトル | 岡山大学環境理工学部研究報告 |
| 発行日 | 2012-03 |
| 巻 | 17巻 |
| 号 | 1号 |
| 開始ページ | 23 |
| 終了ページ | 43 |
| ISSN | 2185-3347 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120004025484 |
| JaLCDOI | 10.18926/fest/48238 |
|---|---|
| タイトル（別表記） | A Survey Study of University Students’ Awareness on Social Contribution and Regional Cooperation |
| フルテキストURL | fest_017_007_021.pdf |
| 著者 | 羅 明振| 荒木 勝| 栗原 考次| |
| 抄録 | Recently, competition among universities has a whole new face, and emphasis is given toward interdependence and interactive evolution between universities and regions. From this social perspective, universities should contribute to regional development by serving the regional society using results of intellectual work, and it is necessary for universities to accomplish social contribution and regional cooperation strategically. One of the most important parts in strategic planning is that students participate in activities for social contribution and regional cooperation. This paper presents a survey of the university students’ awareness on social contribution and regional cooperation using several statistical methods and attempts to find factors which affect activities for social contribution and regional cooperation using logistic regression analysis. |
| キーワード | University students’ awareness social contribution and regional cooperation volunteer activities exploratory factor analysis logistic regression analysis |
| 出版物タイトル | 岡山大学環境理工学部研究報告 |
| 発行日 | 2012-03 |
| 巻 | 17巻 |
| 号 | 1号 |
| 開始ページ | 7 |
| 終了ページ | 21 |
| ISSN | 2185-3347 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120004025483 |
| JaLCDOI | 10.18926/fest/48237 |
|---|---|
| タイトル（別表記） | Basic Reproductive Ratio for Epdiemic Models (Review) |
| フルテキストURL | fest_017_001_006.pdf |
| 著者 | 住田 正憲| 梶原 毅| |
| 抄録 | We review some fundamental results on the basic reproductive ratio of models in epidemiology following several documents. We present the general denition of the basic reproductive ratio and the threshold theorem of for the stability of the disease free equilibrium. All results for non-negative matrices and non singular M-matrices which we need in the denition of the basic reproductive ratio and the proof of the threshold theorem are also presented. All parts of the review are self-contained, and all parts of the proof are given explicitly. |
| キーワード | Basic reproductive ratio epidemic model Non negative matrix M-matrix |
| 出版物タイトル | 岡山大学環境理工学部研究報告 |
| 発行日 | 2012-03 |
| 巻 | 17巻 |
| 号 | 1号 |
| 開始ページ | 1 |
| 終了ページ | 6 |
| ISSN | 2185-3347 |
| 言語 | 日本語 |
| 論文のバージョン | publisher |
| NAID | 120004025482 |