| ID | 53479 |
| フルテキストURL | |
| タイトル（別表記） | Studies on the molecular evolution (affinity maturation) of antibodies: unexpected encounter
|
| 著者 |
大森 斉
岡山大学大学院自然科学研究科
|
| 抄録 | Antibodies are unique proteins in that they improve their affinity for antigens during
antibody responses. This process termed “affinity maturation” is the result of random
hypermutation of immunoglobulin genes in B cells followed by selection of the clones that acquired
high-affinity antibodies. However, what mechanisms are responsible for the induction of
hypermutation and the subsequent B cell selection in germinal centers has remained unknown in
many respects. I would like to talk about our long-lasting studies on these immunologic
mechanisms focusing on the functional role of follicular dendritic cells
|
| 備考 | 記念講演要旨 (Summary of Commemorational Lecture)
|
| 発行日 | 2015-04
|
| 出版物タイトル |
岡山実験動物研究会報
|
| 出版物タイトル（別表記） | Proceedings of Okayama Association for Laboratory Animal Science
|
| 巻 | 31巻
|
| 出版者 | 岡山実験動物研究会
|
| 出版者（別表記） | Okayama Association for Laboratory Animal Science
|
| 開始ページ | 2
|
| 終了ページ | 3
|
| 資料タイプ |
その他
|
| 言語 |
日本語
|
| 論文のバージョン | publisher
|
| 査読 |
無し
|
| Eprints Journal Name | poalas
|
