フルテキストURL | fulltext.pdf |
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著者 | Fukushima, Shinnosuke| Hagiya, Hideharu| Yamamoto, Yukichika| Oguni, Kohei| Hasegawa, Kou| Otsuka, Fumio| |
キーワード | cryptococcal meningitis Cryptococcus neoformans neurosarcoidosis interleukin-6 |
発行日 | 2023-08-15 |
出版物タイトル | Internal Medicine |
巻 | 62巻 |
号 | 16号 |
出版者 | The Japanese Society of Internal Medicine |
開始ページ | 2433 |
終了ページ | 2435 |
ISSN | 0918-2918 |
NCID | AA10827774 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2023 The Japanese Society of Internal Medicine |
論文のバージョン | publisher |
PubMed ID | 36575015 |
DOI | 10.2169/internalmedicine.0879-22 |
Web of Science KeyUT | 001051476800001 |
関連URL | isVersionOf https://doi.org/10.2169/internalmedicine.0879-22 |
JaLCDOI | 10.18926/AMO/65740 |
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フルテキストURL | 77_4_347.pdf |
著者 | Iwamuro, Masaya| Kondo, Takumi| Ennishi, Daisuke| Fujii, Nobuharu| Matsuoka, Ken-ichi| Takahashi, Takahide| Hirabata, Araki| Tanaka, Takehiro| Otsuka, Fumio| Maeda, Yoshinobu| Okada, Hiroyuki| |
抄録 | The feasibility of lymphocyte isolation and flow cytometry using a single endoscopic biopsy specimen from the gastrointestinal tract of patients who have undergone hematopoietic stem cell transplantation has not been investigated. We acquired 51 endoscopic biopsy specimens from the gastrointestinal tract of 35 patients. We divided the flow cytometry samples into two groups: group A, successful lymphocyte isolation (n=24), and group B, incomplete isolation (n=27). We compared the backgrounds of the samples between the groups to reveal crucial elements in the successful isolation of lymphocytes residing in the gastrointestinal tract. Comparison between the groups revealed lymphocyte isolation success rates differed between biopsy sites. Isolation was most successful in samples from the duodenum (8/9, 88.9%), followed by the ileum (4/8, 50.0%), large intestine (4/11, 36.4%), and stomach (8/23, 34.8%). Tacrolimus was used more frequently in group B (92.6%) than in group A (62.5%) (p=0.015). Logistic regression analysis revealed that isolation from the duodenum or ileum was a significant factor for successful isolation, while tacrolimus use was not statistically significant. In conclusion, the duodenum and ileum are more suitable sites than the stomach and colorectum for acquiring samples for flow cytometry. |
キーワード | flow cytometry stem cell transplantation transplantation-associated microangiopathy |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2023-08 |
巻 | 77巻 |
号 | 4号 |
出版者 | Okayama University Medical School |
開始ページ | 347 |
終了ページ | 357 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 37635134 |
Web of Science KeyUT | 001163659800002 |
フルテキストURL | fulltext20230817-04.pdf fig20230817-04.pdf table20230817-04.pdf |
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著者 | Hagiya, Hideharu| Nishimura, Yoshito| Otsuka, Fumio| |
キーワード | Amphotericin B Fungal infection Inhalation Nebulization Aerosolization |
備考 | © 2023 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Oct. 2024.| |
発行日 | 2023-10 |
出版物タイトル | Pulmonary Pharmacology and Therapeutics |
巻 | 82巻 |
出版者 | Elsevier BV |
開始ページ | 102233 |
ISSN | 1094-5539 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2023 Elsevier Ltd. |
論文のバージョン | author |
PubMed ID | 37414132 |
DOI | 10.1016/j.pupt.2023.102233 |
Web of Science KeyUT | 001037489400001 |
関連URL | isVersionOf https://doi.org/10.1016/j.pupt.2023.102233 |
フルテキストURL | fulltext.pdf |
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著者 | Otsuka, Yuki| Hagiya, Hideharu| Sunada, Naruhiko| Otsuka, Fumio| |
キーワード | burnout clerical work medical assistant overwork task shift |
発行日 | 2023-07-25 |
出版物タイトル | Journal of General and Family Medicine |
巻 | 24巻 |
号 | 5号 |
出版者 | Wiley |
開始ページ | 317 |
終了ページ | 319 |
ISSN | 2189-7948 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2023 The Authors. |
論文のバージョン | publisher |
DOI | 10.1002/jgf2.641 |
Web of Science KeyUT | 001035827200001 |
関連URL | isVersionOf https://doi.org/10.1002/jgf2.641 |
フルテキストURL | fulltext.pdf |
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著者 | Oguni, Kohei| Fukushima, Shinnosuke| Yamamoto, Yukichika| Hasegawa, Kou| Hagiya, Hideharu| Inoshita, Naoko| Otsuka, Fumio| |
キーワード | Insulinoma octreotide test somatostatin receptor somatostatin scintigraphy |
発行日 | 2023-08-02 |
出版物タイトル | Clinical Case Reports |
巻 | 11巻 |
号 | 8号 |
出版者 | Wiley |
開始ページ | e7771 |
ISSN | 2050-0904 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2023 The Authors. |
論文のバージョン | publisher |
PubMed ID | 37546161 |
DOI | 10.1002/ccr3.7771 |
Web of Science KeyUT | 001039569500001 |
関連URL | isVersionOf https://doi.org/10.1002/ccr3.7771 |
フルテキストURL | fulltext.pdf |
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著者 | Yamamoto, Yukichika| Otsuka, Yuki| Tokumasu, Kazuki| Sunada, Naruhiko| Nakano, Yasuhiro| Honda, Hiroyuki| Sakurada, Yasue| Hasegawa, Toru| Hagiya, Hideharu| Otsuka, Fumio| |
キーワード | COVID-19 ferritin insulin-like growth factor-I (IGF-I) long COVID myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) |
発行日 | 2023-07-18 |
出版物タイトル | Journal of Clinical Medicine |
巻 | 12巻 |
号 | 14号 |
出版者 | MDPI |
開始ページ | 4737 |
ISSN | 2077-0383 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2023 by the authors. |
論文のバージョン | publisher |
PubMed ID | 37510852 |
DOI | 10.3390/jcm12144737 |
Web of Science KeyUT | 001035871200001 |
関連URL | isVersionOf https://doi.org/10.3390/jcm12144737 |
フルテキストURL | fulltext.pdf |
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著者 | Hagiya, Hideharu| Uno, Mika| Higashionna, Tsukasa| Honda, Hiroyuki| Otsuka, Fumio| |
キーワード | antimicrobial resistance antimicrobial stewardship antibiotics weekdays weekends |
発行日 | 2023-06-15 |
出版物タイトル | Internal Medicine |
巻 | 62巻 |
号 | 12号 |
出版者 | Japanese Society of Internal Medicine |
開始ページ | 1739 |
終了ページ | 1742 |
ISSN | 0918-2918 |
NCID | AA10827774 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2023 by The Japanese Society of Internal Medicine |
論文のバージョン | publisher |
PubMed ID | 36288987 |
DOI | 10.2169/internalmedicine.0707-22 |
Web of Science KeyUT | 001015018300001 |
関連URL | isVersionOf https://doi.org/10.2169/internalmedicine.0707-22 |
フルテキストURL | fulltext20230706-01.pdf fig1_20230706-01.pdf fig2_20230706-01.pdf suppl20230706-01.pdf |
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著者 | Kondo, Takumi| Fujii, Keiko| Fujii, Nobuharu| Sumii, Yuichi| Urata, Tomohiro| Kimura, Maiko| Matsuda, Masayuki| Ikegawa, Shuntaro| Washio, Kana| Fujiwara, Hideaki| Asada, Noboru| Ennishi, Daisuke| Nishimori, Hisakazu| Matsuoka, Ken‐ichi| Otsuka, Fumio| Maeda, Yoshinobu| |
キーワード | blood center operations cellular therapy therapeutic apheresis |
備考 | This is the peer reviewed version of the following article: [Kondo T, Fujii K, Fujii N, Sumii Y, Urata T, Kimura M, et al. Efficient granulocyte collection method using high concentrations of medium molecular weight hydroxyethyl starch. Transfusion. 2023; 63(7): 1344–1353. https://doi.org/10.1111/trf.17450], which has been published in final form at [https://doi.org/10.1111/trf.17450]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| This fulltext file will be available in Jun. 2024.| |
発行日 | 2023-06-09 |
出版物タイトル | Transfusion |
巻 | 63巻 |
号 | 7号 |
出版者 | Wiley |
開始ページ | 1344 |
終了ページ | 1353 |
ISSN | 0041-1132 |
NCID | AA00868753 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2023 AABB. |
論文のバージョン | author |
PubMed ID | 37293978 |
DOI | 10.1111/trf.17450 |
Web of Science KeyUT | 001004560100001 |
関連URL | isVersionOf https://doi.org/10.1111/trf.17450 |
フルテキストURL | fulltext20230711-01.pdf fig20230711-01.pdf |
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著者 | Takase, Ryosuke| Hagiya, Hideharu| Fujimori, Takumi| Yokoyama, Yukika| Iio, Koji| Honda, Hiroyuki| Hasegawa, Kou| Otsuka, Fumio| |
備考 | © 2023 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Jul. 2024.| |
発行日 | 2023-09 |
出版物タイトル | Journal of Infection and Chemotherapy |
巻 | 29巻 |
号 | 9号 |
出版者 | Elsevier Ltd. |
開始ページ | 919 |
終了ページ | 921 |
ISSN | 1341-321X |
NCID | AA11057978 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2023 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. |
論文のバージョン | author |
PubMed ID | 37230385 |
DOI | 10.1016/j.jiac.2023.05.017 |
Web of Science KeyUT | 001050515100001 |
関連URL | isVersionOf https://doi.org/10.1016/j.jiac.2023.05.017 |
フルテキストURL | fulltext.pdf |
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著者 | Hagiya, Hideharu| Nakano, Yasuhiro| Furukawa, Masanori| Sunada, Naruhiko| Hasegawa, Toru| Sakurada, Yasue| Hasegawa, Kou| Yamamoto, Koichiro| Ogawa, Hiroko| Obara, Takafumi| Ageta, Kouhei| Matsumoto, Naomi| Matsuo, Rumi| Kadowaki, Tomoka| Higashikage, Akihito| Hikita, Takao| Yorifuji, Takashi| Toyooka, Shinichi| Maeda, Yoshinobu| Yokokura, Yoshinori| Otsuka, Fumio| Nakayama, Masanori| |
備考 | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-022-24464-3| |
発行日 | 2022-11-30 |
出版物タイトル | Scientific Reports |
巻 | 12巻 |
号 | 1号 |
出版者 | nature portfolio |
開始ページ | 20628 |
ISSN | 2045-2322 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © The Author(s) 2022 |
論文のバージョン | publisher |
PubMed ID | 36450786 |
DOI | 10.1038/s41598-022-24464-3 |
Web of Science KeyUT | 001002757900008 |
関連URL | isVersionOf https://doi.org/10.1038/s41598-022-24464-3 |
JaLCDOI | 10.18926/AMO/65490 |
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フルテキストURL | 77_3_255.pdf |
著者 | Fukushima, Shinnosuke| Hagiya, Hideharu| Uda, Kazuhiro| Gotoh, Kazuyoshi| Otsuka, Fumio| |
抄録 | Antimicrobial resistance is an emerging global threat that must be addressed using a multidisciplinary approach. This study aimed to raise awareness of high-level antimicrobial-resistant (AMR) pathogens in Japan by comparing their recent prevalences among prefectures, particularly Okayama. Data for the isolation proportions of meropenem-resistant Pseudomonas aeruginosa, methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, cefotaxime-resistant Escherichia coli and Klebsiella pneumoniae, and levofloxacin-resistant E. coli and K. pneumoniae were collected from the Japan Nosocomial Infections Surveillance, a national database sponsored by the Japanese Ministry of Health, Labour, and Welfare, between 2018 and 2021. The average isolated proportions of the seven AMR pathogens were higher in Okayama compared to other prefectures: the worst (19.9%) was meropenem-resistant P. aeruginosa, the sixth worst (57.2%) was methicillin-resistant S. aureus, the eighth worst (3.3%) was vancomycin-resistant E. faecium, the second (37.8%) and fifth worst (17.6%) were cefotaxime-resistant E. coli and K. pneumoniae, respectively, and the fourth (49.9%) and third worst (8.7%) were levofloxacin-resistant E. coli and K. pneumoniae, respectively. Our study highlights the notably high prevalences of representative AMR pathogens in Okayama, suggesting the need for fundamental infection prevention and control by healthcare professionals, promoting antimicrobial stewardship, and educating undergraduates and postgraduates in Okayama. |
キーワード | antimicrobial resistance antimicrobial stewardship epidemiology infection prevention and control Japan Nosocomial Infections Surveillance |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2023-06 |
巻 | 77巻 |
号 | 3号 |
出版者 | Okayama University Medical School |
開始ページ | 255 |
終了ページ | 262 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 37357626 |
Web of Science KeyUT | 001026279600003 |
JaLCDOI | 10.18926/AMO/65488 |
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フルテキストURL | 77_3_235.pdf |
著者 | Kuraoka, Sakiko| Iwamuro, Masaya| Satomi, Takuya| Yamazaki, Tatsuhiro| Hamada, Kenta| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kato, Hironari| Otsuka, Fumio| Okada, Hiroyuki| |
抄録 | Changes in hormone levels in patients with cancer cachexia after anamorelin administration have not been fully investigated. This study aimed to determine how anamorelin affects the endocrine system in patients with gastrointestinal cancer and cachexia. We prospectively enrolled 13 patients and comprehensively investigated their body weight and levels of serum albumin, hemoglobin A1c (HbA1c), and hormones before (week 0) and 3 and 12 weeks after anamorelin administration. The variables were evaluated at week 3 in 9 patients and at week 12 in 5 patients. At week 3, anamorelin administration resulted in body weight gain and increased the levels of growth hormone and HbA1c, as well as insulin-like growth factor-1 standard deviation scores (IGF-1 SD scores). At the same time, negative correlations were observed between ΔIGF-1 SD score and Δthyroidstimulating hormone (TSH) and between ΔIGF-1 SD score and Δfree testosterone. ΔBody weight and ΔIGF-1 SD score correlated positively at week 12. These results suggest that TSH and free testosterone levels can be affected 3 weeks after anamorelin administration; however, those variables tend to return to a state of equilibrium, and anabolic effects of anamorelin appear in long-term (≥ 12 weeks) users. |
キーワード | anamorelin body weight cancer cachexia endocrine system |
Amo Type | Original Article |
出版物タイトル | Acta Medica Okayama |
発行日 | 2023-06 |
巻 | 77巻 |
号 | 3号 |
出版者 | Okayama University Medical School |
開始ページ | 235 |
終了ページ | 241 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 37357624 |
Web of Science KeyUT | 001026279600001 |
フルテキストURL | fulltext.pdf |
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著者 | Fujita, Kana| Otsuka, Yuki| Sunada, Naruhiko| Honda, Hiroyuki| Tokumasu, Kazuki| Nakano, Yasuhiro| Sakurada, Yasue| Obika, Mikako| Hagiya, Hideharu| Otsuka, Fumio| |
キーワード | COVID-19 aftercare clinic (CAC) headache quality of life (QOL) long COVID post COVID-19 condition (PCC) |
発行日 | 2023-05-18 |
出版物タイトル | Journal of Clinical Medicine |
巻 | 12巻 |
号 | 10号 |
出版者 | MDPI |
開始ページ | 3533 |
ISSN | 2077-0383 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2023 by the authors. |
論文のバージョン | publisher |
PubMed ID | 37240639 |
DOI | 10.3390/jcm12103533 |
Web of Science KeyUT | 000997859300001 |
関連URL | isVersionOf https://doi.org/10.3390/jcm12103533 |
フルテキストURL | fulltext20230512-02.pdf fig20230512-02.pdf |
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著者 | Yamamoto, Koichiro| Otsuka, Fumio| |
備考 | © 2022 Mayo Foundation for Medical Education and Research. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at https://doi.org/10.1016/j.mayocp.2022.01.010.| |
発行日 | 2022-04 |
出版物タイトル | Mayo Clinic Proceedings |
巻 | 97巻 |
号 | 4号 |
出版者 | Elsevier BV |
開始ページ | 652 |
終了ページ | 652 |
ISSN | 0025-6196 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2022 Mayo Foundation for Medical Education and Research |
論文のバージョン | author |
PubMed ID | 35379418 |
DOI | 10.1016/j.mayocp.2022.01.010 |
Web of Science KeyUT | 000795076500005 |
関連URL | isVersionOf https://doi.org/10.1016/j.mayocp.2022.01.010 |
フルテキストURL | fulltext20230512-01.pdf fig20230512-01.pdf |
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著者 | Yamamoto, Koichiro| Honda, Hiroyuki| Otsuka, Fumio| |
備考 | © 2022 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at https://doi.org/10.1016/j.amjmed.2022.01.033.| This fulltext file will be available in May 2023.| |
発行日 | 2022-05 |
出版物タイトル | The American Journal of Medicine |
巻 | 135巻 |
号 | 5号 |
出版者 | Elsevier BV |
開始ページ | e106 |
終了ページ | e106 |
ISSN | 0002-9343 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2022 Elsevier Inc. |
論文のバージョン | author |
PubMed ID | 35131304 |
DOI | 10.1016/j.amjmed.2022.01.033 |
Web of Science KeyUT | 000830333300003 |
関連URL | isVersionOf https://doi.org/10.1016/j.amjmed.2022.01.033 |
フルテキストURL | fulltext20230508-05.pdf table20230508-05.pdf fig20230508-05.pdf |
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著者 | Fujimori, Takumi| Hagiya, Hideharu| Iio, Koji| Yamasaki, Osamu| Miyamoto, Yuji| Hoshino, Yoshihiko| Kakehi, Ayaka| Okura, Mami| Minabe, Hiroshi| Yokoyama, Yukika| Otsuka, Fumio| Higashikage, Akihito| |
キーワード | Buruli ulcer Mycobacterium ulcerans Mycobacterium ulcerans subsp shinshuense 16S rRNA sequencing analysis |
備考 | © 2023 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at https://doi.org/10.1016/j.jiac.2023.02.009. | This fulltext file will be available in May 2024.| |
発行日 | 2023-05 |
出版物タイトル | Journal of Infection and Chemotherapy |
巻 | 29巻 |
号 | 5号 |
出版者 | Elsevier BV |
開始ページ | 523 |
終了ページ | 526 |
ISSN | 1341-321X |
NCID | AA11057978 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2023 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. |
論文のバージョン | author |
PubMed ID | 36813163 |
DOI | 10.1016/j.jiac.2023.02.009 |
Web of Science KeyUT | 000972082300001 |
関連URL | isVersionOf https://doi.org/10.1016/j.jiac.2023.02.009 |
フルテキストURL | fulltext20230508-04.pdf |
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著者 | Hagiya, Hideharu| Otsuka, Yuki| Otsuka, Fumio| |
備考 | © 2022 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at https://doi.org/10.1016/j.jns.2022.120232.| This fulltext file will be available in May 2023.| |
発行日 | 2022-05-15 |
出版物タイトル | Journal of the Neurological Sciences |
巻 | 436巻 |
出版者 | Elsevier BV |
開始ページ | 120232 |
ISSN | 0022-510X |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © 2022 Elsevier B.V. |
論文のバージョン | author |
PubMed ID | 35339066 |
DOI | 10.1016/j.jns.2022.120232 |
Web of Science KeyUT | 000795473800002 |
関連URL | isVersionOf https://doi.org/10.1016/j.jns.2022.120232 |
タイトル(別表記) | Experience with a nosocomial cluster of novel coronavirus infection and the cluster response algorithm |
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著者 | 藤田 浩二| 大重 和樹| 門脇 知花| 頼藤 貴志| 大塚 文男| |
抄録 | The novel coronavirus disease (COVID-19) pandemic that began in 2019 is yet to end, as of the summer of 2022. During the pandemic, community-acquired infections spread easily to healthcare-associated facilities, resulting in COVID-19 clusters among high-risk individuals that have been difficult to contain. Our regional base hospital also experienced a nosocomial cluster of COVID-19 in October 2020 that took 30 days to contain and affected 9 hospital staff and 14 patients. Six patients died due to COVID-19, and six died due to COVID-19-related complications. Two patients were discharged alive. Patient characteristics included ① advanced age (79.0±8.1 years), ② dementia (64.3%), ③ low Prognostic Nutrition Index (31.1 ±7.9), ④ zinc deficiency (50.2±13.1μg/dL), ⑤ vitamin C deficiency (1.6±1.9μg/mL), ⑥ elevated urea nitrogen-to-creatinine ratio (27.4±23.5), ⑦ anticancer and immunosuppressive drug use (78.6%), and ⑧ malignancy (75.6%). This cluster had a very high mortality rate, but the viral spread was contained in a short period. Algorithmizing the cluster response was crucial to controlling this cluster. We report on our actual cluster response algorithm, as well as our strategy and response procedure during the pandemic. |
キーワード | 新型コロナウイルス感染症(COVID-19) 院内クラスター(nosocomial cluster) 対応アルゴリズム(response algorithm) |
出版物タイトル | 岡山医学会雑誌 |
発行日 | 2023-04-01 |
巻 | 135巻 |
号 | 1号 |
開始ページ | 22 |
終了ページ | 33 |
ISSN | 0030-1558 |
関連URL | isVersionOf https://doi.org/10.4044/joma.135.22 |
言語 | 日本語 |
著作権者 | Copyright (c) 2023 岡山医学会 |
論文のバージョン | publisher |
DOI | 10.4044/joma.135.22 |
フルテキストURL | fulltext.pdf |
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著者 | Otsuka, Yuki| Hagiya, Hideharu| Takahashi, Misa| Fukushima, Shinnosuke| Maeda, Ruri| Sunada, Naruhiko| Yamada, Haruto| Kishida, Masayuki| Fujita, Koji| Otsuka, Fumio| |
発行日 | 2023-01-12 |
出版物タイトル | Scientific Reports |
巻 | 13巻 |
号 | 1号 |
出版者 | Nature Research |
開始ページ | 647 |
ISSN | 2045-2322 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
OAI-PMH Set | 岡山大学 |
著作権者 | © The Author(s) 2023 |
論文のバージョン | publisher |
PubMed ID | 36635328 |
DOI | 10.1038/s41598-022-27330-4 |
Web of Science KeyUT | 000962604100025 |
関連URL | isVersionOf https://doi.org/10.1038/s41598-022-27330-4 |
JaLCDOI | 10.18926/AMO/65151 |
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フルテキストURL | 77_2_203.pdf |
著者 | Fukushima, Shinnosuke| Hagiya, Hideharu| Iio, Koji| Honda, Hiroyuki| Ishida, Tomoharu| Nagaoka, Hirokazu| Hasegawa, Kou| Otsuka, Fumio| |
抄録 | Granulicatella species are rare, nutritionally variant streptococci that cause infective endocarditis. Their clinical and microbiological characteristics remain unknown. We reviewed five years of Granulicatella cases in our hospital database (Jan 2017-Jun 2022), finding 6 Granulicatella adiacens cases and 1 Granulicatella elegans case. Clinical backgrounds and bacteremia sources were diverse; 3 cases developed polymicrobial bacteremia. Antimicrobial testing showed non-susceptibility to penicillin G in 4 of 7 cases (57.1%), and high susceptibility to carbapenems and vancomycin in all cases. Determining optimal antibiotic therapy for Granulicatella infections is vital in this era of antimicrobial resistance. |
キーワード | antimicrobial resistance bacteremia Granulicatella species nutritionally variant streptococci |
Amo Type | Case Report |
出版物タイトル | Acta Medica Okayama |
発行日 | 2023-04 |
巻 | 77巻 |
号 | 2号 |
出版者 | Okayama University Medical School |
開始ページ | 203 |
終了ページ | 207 |
ISSN | 0386-300X |
NCID | AA00508441 |
資料タイプ | 学術雑誌論文 |
言語 | 英語 |
著作権者 | Copyright Ⓒ 2023 by Okayama University Medical School |
論文のバージョン | publisher |
査読 | 有り |
PubMed ID | 37094959 |
Web of Science KeyUT | 000982563800002 |