JaLCDOI 10.18926/AMO/67868
フルテキストURL 78_6_429.pdf
著者 Kubota, Risa| Bekku, Kensuke| Katayama, Satoshi| Iwata, Takehiro| Nishimura, Shingo| Edamura, Kohei| Kobayashi, Tomoko| Kobayashi, Yasuyuki| Araki, Motoo|
抄録 Although partial nephrectomy (PN) is preferred over radical nephrectomy (RN) for preserving renal function in patients with cT1 renal cancer, its impact on cardiovascular events (CVe) remains controversial. This study aimed to compare PN and RN in regard to the occurrence of CVe, including cerebrovascular events and exacerbation of hypertension (HT). We retrospectively analyzed 418 consecutive patients who underwent PN or RN for cT1 renal cancer. Propensity score-matching analysis was used to adjust for imbalances between patients who underwent PN and RN, leaving 102 patients in each group. The 5-year probability of cumulative CVe incidence was 6% in the PN group and 12% in the RN group (p=0.03), with a median follow-up of 73.5 months. The statistical significance was retained after propensity score matching for patients without preoperative proteinuria (p=0.03). For all CVe including cerebrovascular events and exacerbation of HT analyzed, PN provided a lower probability of occurrence than RN in patients with small renal cancers.
キーワード chronic kidney disease hypertension nephrectomy proteinuria
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2024-12
78巻
6号
出版者 Okayama University Medical School
開始ページ 429
終了ページ 437
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 39719315
Web of Science KeyUT 001397799300001
フルテキストURL fulltext.pdf
著者 Bekku, Kensuke| Kawada, Tatsushi| Sekito, Takanori| Yoshinaga, Kasumi| Maruyama, Yuki| Yamanoi, Tomoaki| Tominaga, Yusuke| Sadahira, Takuya| Katayama, Satoshi| Iwata, Takehiro| Nishimura, Shingo| Edamura, Kohei| Kobayashi, Tomoko| Kobayashi, Yasuyuki| Araki, Motoo| Niibe, Yuzuru|
キーワード renal cell carcinoma oligo-metastasis oligo-recurrence oligo-progression metastasectomy stereotactic body radiation therapy
発行日 2023-12-17
出版物タイトル Cancers
15巻
24号
出版者 MDPI
開始ページ 5873
ISSN 2072-6694
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 by the authors.
論文のバージョン publisher
PubMed ID 38136417
DOI 10.3390/cancers15245873
Web of Science KeyUT 001131355800001
関連URL isVersionOf https://doi.org/10.3390/cancers15245873
フルテキストURL fulltext.pdf
著者 Sakaeda, Kazuma| Sadahira, Takuya| Maruyama, Yuki| Iwata, Takehiro| Watanabe, Masami| Wada, Koichiro| Araki, Motoo|
キーワード antimicrobial resistance Escherichia coli urinary tract infections flomoxef ST131
発行日 2023-03-06
出版物タイトル Antibiotics
12巻
3号
出版者 MDPI
開始ページ 522
ISSN 2079-6382
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2023 by the authors.
論文のバージョン publisher
PubMed ID 36978389
DOI 10.3390/antibiotics12030522
Web of Science KeyUT 000952995400001
関連URL isVersionOf https://doi.org/10.3390/antibiotics12030522
フルテキストURL fulltext20230317-1.pdf
著者 Tominaga, Yusuke| Fujii, Masanori| Sadahira, Takuya| Katayama, Satoshi| Iwata, Takehiro| Nishimura, Shingo| Bekku, Kensuke| Edamura, Kohei| Kobayashi, Tomoko| Kobayashi, Yasuyuki| Kiura, Katsuyuki| Maeda, Yoshinobu| Wada, Koichiro| Araki, Motoo|
キーワード bladder tuberculosis bacillus Calmette-Guerin bladder cancer ureteral stricture voiding dysfunction
発行日 2022-12-20
出版物タイトル Molecular and Clinical Oncology
18巻
2号
出版者 Spandidos Publications
開始ページ 7
ISSN 2049-9450
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © Tominaga et al.
論文のバージョン publisher
PubMed ID 36761388
DOI 10.3892/mco.2022.2603
Web of Science KeyUT 000928771000001
関連URL isVersionOf https://doi.org/10.3892/mco.2022.2603
JaLCDOI 10.18926/AMO/62820
フルテキストURL 75_6_763.pdf
著者 Iwata, Takehiro| Sadahira, Takuya| Maruyama, Yuki| Sekito, Takanori| Yoshinaga, Kasumi| Watari, Shogo| Nagao, Kentaro| Kawada, Tatsushi| Tominaga, Yusuke| Nishimura, Shingo| Takamoto, Atsushi| Sako, Tomoko| Edamura, Kohei| Kobayashi, Yasuyuki| Araki, Motoo| Ishii, Ayano| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| Wada, Koichiro|
抄録 The aim of this ongoing trial is to evaluate the clinical efficacy and safety of sitafloxacin (STFX) 200 mg once daily (QD) for 7 days in patients with refractory genitourinary tract infections, which include recurrent or complicated cystitis, complicated pyelonephritis, bacterial prostatitis, and epididymitis. The primary endpoint is the microbiological efficacy at 5-9 days after the last administration of STFX. Recruitment began in February 2021, and the target total sample size is 92 participants.
キーワード genitourinary tract infections fluoroquinolone resistance extended-spectrum beta-lactamase
Amo Type Clinical Study Protocol
出版物タイトル Acta Medica Okayama
発行日 2021-12
75巻
6号
出版者 Okayama University Medical School
開始ページ 763
終了ページ 766
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 34955548
Web of Science KeyUT 000735319800006
NAID 120007180272
JaLCDOI 10.18926/AMO/62810
フルテキストURL 75_6_705.pdf
著者 Iwata, Takehiro| Maruyama, Yuki| Kawada, Tatsushi| Sadahira, Takuya| Katayama, Satoshi| Takamoto, Atsushi| Sako, Tomoko| Wada, Koichiro| Edamura, Kohei| Kobayashi, Yasuyuki| Araki, Motoo| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo|
抄録 Optimal neoadjuvant hormone therapy (NHT) for reducing prostate cancer (PC) patients’ prostate volume pre-brachytherapy is controversial. We evaluated the differential impact of neoadjuvant gonadotropin-releasing hormone (GnRH) antagonist versus agonist on post-brachytherapy testosterone recovery in 112 patients treated pre-brachytherapy with NHT (GnRH antagonist, n=32; GnRH agonists, n=80) (Jan. 2007-June 2019). We assessed the effects of patient characteristics and a GnRH analogue on testosterone recovery with logistic regression and a propensity score analysis (PSA). There was no significant difference in the rate of testosterone recovery to normal levels (> 300 ng/dL) between the GnRH antagonist and agonists (p=0.07). The GnRH agonists induced a significantly more rapid testosterone recovery rate at 3 months post-brachytherapy versus the GnRH antagonist (p<0.0001); there was no difference in testosterone recovery at 12 months between the GnRH antagonist/agonists (p=0.8). In the multivariate analysis, no actor was associated with testosterone recovery. In the PSA, older age and higher body mass index (BMI) were significantly associated with longer testosterone recovery. Post-brachytherapy testosterone recovery was quicker with the neoadjuvant GnRH agonists than the antagonist, and the testosterone recovery rate was significantly associated with older age and higher BMI. Long-term follow-ups are needed to determine any differential effects of GnRH analogues on the quality of life of brachytherapy-treated PC patients.
キーワード testosterone recovery GnRH antagonist GnRH agonist brachytherapy prostate cancer
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2021-12
75巻
6号
出版者 Okayama University Medical School
開始ページ 705
終了ページ 711
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 34955538
Web of Science KeyUT 000735297900006
NAID 120007180282
フルテキストURL fulltext.pdf
著者 Wada, Koichiro| Araki, Motoo| Tanimoto, Ryuta| Sadahira, Takuya| Watari, Shogo| Maruyama, Yuki| Mitsui, Yosuke| Nakajima, Hirochika| Acosta, Herik| Katayama, Satoshi| Iwata, Takehiro| Nishimura, Shingo| Takamoto, Atsushi| Sako, Tomoko| Edamura, Kohei| Kobayashi, Yasuyuki| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo|
キーワード Photodynamic diagnosis 5-Aminolevulinic acid ALA-PDD Upper urinary tract urothelial carcinoma VISERA ELITE video system
発行日 2021-03-25
出版物タイトル BMC urology
21巻
1号
出版者 BMC
開始ページ 45
ISSN 1471-2490
NCID AA12035460
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © The Author(s) 2021.
論文のバージョン publisher
PubMed ID 33765999
DOI 10.1186/s12894-021-00819-2
NAID 120007008530
Web of Science KeyUT 000632906900001
関連URL isVersionOf https://doi.org/10.1186/s12894-021-00819-2
フルテキストURL fulltext.pdf
著者 Janisch, Florian| Abufaraj, Mohammad| Fajkovic, Harun| Kimura, Shoji| Iwata, Takehiro| Nyirady, Peter| Rink, Michael| Shariat, Shahrokh F.|
キーワード Disease management Primary urethral carcinoma Prognosis Therapy Treatment
発行日 2019-07-13
出版物タイトル European Urology Focus
5巻
5号
出版者 Elsevier
開始ページ 722
終了ページ 734
ISSN 24054569
資料タイプ 学術雑誌論文
言語 英語
OAI-PMH Set 岡山大学
著作権者 © 2019 European Association of Urology. Published by Elsevier B.V.
論文のバージョン publisher
PubMed ID 31307949
DOI 10.1016/j.euf.2019.07.001
Web of Science KeyUT 000490140000008
関連URL isVersionOf https://doi.org/10.1016/j.euf.2019.07.001