| JaLCDOI | 10.18926/AMO/60803 |
|---|---|
| フルテキストURL | 74_5_427.pdf |
| 著者 | Hiraoka, Tomohiro| Senoo, Haruka| Yamazaki, Yuka| Suenobu, Kosaku| Tsukahara, Hirokazu| |
| 抄録 | Polydactyly is one of the most common foot congenital anomalies. It is often detected immediately after birth, but the diagnosis can sometimes be delayed if the symptoms are less evident. A 2-year-old girl with a complaint of recurrent bleeding from the right toenail was diagnosed with foot polydactyly. She underwent corrective surgery, and her family was satisfied with the outcome. Although the diagnosis of polydactyly may be difficult in cases with minor nail problems, further radiographic evaluation will be needed for the improvement of the patient’s quality of life. |
| キーワード | polydactyly hyperdactyly hexadactyly |
| Amo Type | Case Report |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2020-10 |
| 巻 | 74巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 427 |
| 終了ページ | 429 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2020 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 33106699 |
| Web of Science KeyUT | 000581970100008 |
| NAID | 120006892929 |
| フルテキストURL | PI_62_5_587_592.pdf PI_62_5_Fig1.tif PI_62_5_Fig2.tif |
|---|---|
| 著者 | Miyahara, Hiroyuki| Akiyama, Tomoyuki| Hasegawa, Kosei| Akiyama, Mari| Oka, Makio| Kobayashi, Katsuhiro| Tsukahara, Hirokazu| |
| キーワード | adrenocorticotropic hormone therapy calcium crystal renal tubular epithelial cell urinary sediment |
| 備考 | This is the peer reviewed version of the following article: Miyahara, Hiroyuki et.al. "Laboratory changes during adrenocorticotropic hormone therapy associated with renal calcified lesions" Pediatrics International 62(5) 587-592 (2020), which has been published in final form at https://doi.org/10.1111/ped.14158. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.| |
| 発行日 | 2020-01-19 |
| 出版物タイトル | Pediatrics International |
| 巻 | 62巻 |
| 号 | 5号 |
| 出版者 | Wiley |
| 開始ページ | 587 |
| 終了ページ | 592 |
| ISSN | 1328-8067 |
| NCID | AA11320483 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2020 Japan Pediatric Society |
| 論文のバージョン | author |
| PubMed ID | 31957090 |
| DOI | 10.1111/ped.14158 |
| Web of Science KeyUT | 000536494300014 |
| 関連URL | isVersionOf https://doi.org/10.1111/ped.14158 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Tsuge, Mitsuru| Miyamoto, Machiko| Miyawaki, Reiji| Kondo, Yoichi| Tsukahara, Hirokazu| |
| キーワード | Child Hemophagocytic lymphohistiocytosis Invasive pneumococcal disease Pneumococcal conjugate vaccine Serotype replacement |
| 発行日 | 2020-01-13 |
| 出版物タイトル | BMC Pediatrics |
| 巻 | 20巻 |
| 号 | 1号 |
| 出版者 | BMC |
| ISSN | 1471-2431 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s). 2020 |
| 論文のバージョン | publisher |
| PubMed ID | 31931763 |
| DOI | 10.1186/s12887-020-1915-7 |
| Web of Science KeyUT | 000514577300003 |
| 関連URL | isVersionOf https://doi.org/10.1186/s12887-020-1915-7 |
| フルテキストURL | fulltext.pdf fulltext2.pdf |
|---|---|
| 著者 | Fujii, Yosuke| Yashiro, Masato| Yamada, Mutsuko| Kikkawa, Tomonobu| Nosaka, Nobuyuki| Saito, Yukie| Tsukahara, Kohei| Ikeda, Masanori| Morishima, Tsuneo| Tsukahara, Hirokazu| |
| 発行日 | 2018-03-14 |
| 出版物タイトル | Disease Markers |
| 出版者 | Hindawi |
| 開始ページ | 2380179 |
| ISSN | 0278-0240 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © 2018 Yosuke Fujii et al. |
| 論文のバージョン | publisher |
| PubMed ID | 29725488 |
| DOI | 10.1155/2018/2380179 |
| Web of Science KeyUT | 000428395400001 |
| 関連URL | isVersionOf https://doi.org/10.1155/2018/2380179 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Knaup, Emily| Nosaka, Nobuyuki| Yorifuji, Takashi| Tsukahara, Kohei| Naitou, Hiromichi| Tsukahara, Hirokazu| Nakao, Atsunori| the JaRPAC Study Group| |
| キーワード | Decision support Intensive care Length of stay Mortality Outcome Pediatric Risk Prediction rules Scoring system |
| 発行日 | 2019-07-29 |
| 出版物タイトル | Journal of Intensive Care |
| 巻 | 7巻 |
| 出版者 | BMC |
| 開始ページ | 38 |
| ISSN | 2052-0492 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | © The Author(s). |
| 論文のバージョン | publisher |
| PubMed ID | 31384469 |
| DOI | 10.1186/s40560-019-0392-2 |
| Web of Science KeyUT | 000477892900001 |
| 関連URL | isVersionOf https://doi.org/10.1186/s40560-019-0392-2 |
| フルテキストURL | CPE28_4_155.pdf |
|---|---|
| 著者 | Hasegawa, Kosei| Ihoriya, Hiromi| Futagawa, Natsuko| Higuchi, Yousuke| Tsuchiya, Hiroki| Shibata, Takashi| Hayashi, Yumiko| Kobayashi, Katsuhiro| Tsukahara, Hirokazu| |
| キーワード | developmental delay polyuria polydipsia fever poor weight gain |
| 備考 | 本文データは学協会の許諾に基づきCiNiiから複製したものである| |
| 発行日 | 2019-10-19 |
| 出版物タイトル | Clinical Pediatric Endocrinology |
| 巻 | 28巻 |
| 号 | 4号 |
| 出版者 | Japanese Society for Pediatric Endocrinology |
| 開始ページ | 155 |
| 終了ページ | 158 |
| ISSN | 0918-5739 |
| NCID | AA11006467 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 著作権者 | The Japanese Society for Pediatric Endocrinology |
| 論文のバージョン | publisher |
| PubMed ID | 31666769 |
| DOI | 10.1297/cpe.28.155 |
| Web of Science KeyUT | 000491469300008 |
| 関連URL | isVersionOf https://doi.org/10.1297/cpe.28.155 |
| JaLCDOI | 10.18926/AMO/54987 |
|---|---|
| フルテキストURL | 71_2_179.pdf |
| 著者 | Nosaka, Nobuyuki| Tsukahara, Kohei| Knaup, Emily| Yabuuchi, Toshihiko| Kikkawa, Tomonobu| Fujii, Yosuke| Yashiro, Masato| Yasuhara, Takao| Okada, Ayumi| Ugawa, Toyomu| Nakao, Atsunori| Tsukahara, Hirokazu| Date, Isao| |
| 抄録 | Newly published clinical practice guidelines recommend intracranial pressure (ICP) monitoring in critical care for the management of pediatric acute encephalopathy (pAE), but the utility of ICP monitoring for pAE has been poorly studied. We recently performed direct ICP monitoring for two patients. We observed that although the direct ICP monitoring had clinical benefits with less body weight gain and no vasopressor use in both cases, this monitoring technique is still invasive. Future studies should determine the utility of non-invasive ICP monitoring systems in pAE to further improve the quality of intensive-care management. |
| キーワード | cerebral perfusion encephalopathy child intracranial pressure neurological intensive care |
| Amo Type | Short Communication |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2017-04 |
| 巻 | 71巻 |
| 号 | 2号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 179 |
| 終了ページ | 180 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2017 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28420900 |
| 著者 | Nosaka, Nobuyuki| Okada, Ayumi| Tsukahara, Hirokazu| |
|---|---|
| 発行日 | 2017-02 |
| 出版物タイトル | Acta Medica Okayama |
| 巻 | 71巻 |
| 号 | 1号 |
| 資料タイプ | 学術雑誌論文 |
| JaLCDOI | 10.18926/AMO/54819 |
| JaLCDOI | 10.18926/AMO/54805 |
|---|---|
| フルテキストURL | 70_6_435.pdf |
| 著者 | Yamashita, Miho| Hasegawa, Kosei| Higuchi, Yousuke| Miyai, Takayuki| Okada, Ayumi| Tanaka, Hiroyuki| Tsukahara, Hirokazu| |
| 抄録 | The urinary cross-linked N-terminal telopeptide of type I collagen (uNTx) levels in infantile osteogenesis imperfecta (OI) have not been well studied. Here we investigated the levels of uNTx in infants with OI and healthy infants. We collected spot urine samples from 30 infants with OI (male/female, 14/16; Sillence classification, I/II/III/IV: 15/3/6/6; age, 5.2±4.4 months) and 120 healthy infants (male/female, 75/45; age, 5.1±4.1 months) for the measurement of uNTx levels. The uNTx levels of the OI infants were significantly lower than those of the healthy infants (mean±SD, 1,363.7±530.1 vs. 2,622.2±1,202.6 nmol BCE/mmol Cr; p＜0.001). The uNTx levels of the infants with type I OI were significantly lower than those of the age-matched healthy infants, although an overlap was observed between the 2 groups. Among the 1-month-old infants, the uNTx levels of the infants with types I, III or IV OI were significantly lower than those of the healthy infants, without overlap (1,622.5±235.8 vs. 3,781.0±1,027.1 nmol BCE/mmol Cr; p＜0.001). These results indicate that uNTx levels are significantly lower in infants with OI than in healthy infants, and they suggest that uNTx might be useful as a reference for diagnosing OI. |
| キーワード | bone resorption marker bone turnover bone mass |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-12 |
| 巻 | 70巻 |
| 号 | 6号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 435 |
| 終了ページ | 439 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 28003667 |
| フルテキストURL | fulltext.pdf |
|---|---|
| 著者 | Takahashi Nobumasa| Nojima, Ikuko| Araki, Tooru| Takasugi, Mizue| Sakane, Tomoko| Kodera, Aya| Ikeda, Masanori| Tsukahara, Hirokazu| |
| キーワード | Norovirus false positive immunochromatography neonate rapid detection test specificity |
| 発行日 | 2015-09-03 |
| 出版物タイトル | Journal of International Medical Research |
| 巻 | 43巻 |
| 号 | 5号 |
| 出版者 | Sage |
| 開始ページ | 648 |
| 終了ページ | 652 |
| ISSN | 0300-0605 |
| NCID | AA00700686 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| OAI-PMH Set | 岡山大学 |
| 論文のバージョン | publisher |
| PubMed ID | 26338763 |
| DOI | 10.1177/0300060515592902 |
| Web of Science KeyUT | 000361592500006 |
| 関連URL | isVersionOf https://doi.org/10.1177/0300060515592902 |
| JaLCDOI | 10.18926/AMO/54500 |
|---|---|
| フルテキストURL | 70_4_255.pdf |
| 著者 | Nosaka, Nobuyuki| Fujiwara, Takeo| Knaup, Emily| Okada, Ayumi| Tsukahara, Hirokazu| |
| 抄録 | Estimation methods for pediatric weight have not been evaluated for Japanese children. This study aimed to assess the accuracy of mothersʼ reports of their childrenʼs weight in Japan. We also evaluated potential alternatives to the estimation of weight, including the Broselow tape (BT), Advanced Pediatric Life Support (APLS), and Parkʼs formulae. We prospectively collected cross-sectional data on a convenience sample of 237 children aged less than 10 years who presented to a general pediatric outpatient clinic with their mothers. Each weight estimation method was evaluated using Bland-Altman plots and by calculating the proportion within 10 and 20 of the measured weight. Mothersʼ reports of weight were the most accurate method, with 94.9 within 10 of the measured weight, the lowest mean difference (0.27kg), and the shortest 95 limit of agreement (－1.4 to 1.9kg). The BT was the most reliable alternative, followed by APLS and Parkʼs formulae. Mothersʼ reports of their children ʼs weight are more accurate than other weight estimation methods. When no report of a childʼs weight by the mother is available, BT is the best alternative. When an aged-based formula is the only option, the APLS formula is preferred. |
| キーワード | body weight child estimation techniques mothers, parents |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2016-08 |
| 巻 | 70巻 |
| 号 | 4号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 255 |
| 終了ページ | 259 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2016 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 27549669 |
| Web of Science KeyUT | 000384748600004 |
| タイトル（別表記） | Basic and clinical research regarding vascular endothelial function |
|---|---|
| フルテキストURL | 127_187.pdf |
| 著者 | 塚原 宏一| |
| キーワード | アルギニン代謝 一酸化窒素 ガス生物学 血管内皮学 酸化ストレス |
| 出版物タイトル | 岡山医学会雑誌 |
| 発行日 | 2015-12-01 |
| 巻 | 127巻 |
| 号 | 3号 |
| 開始ページ | 187 |
| 終了ページ | 195 |
| ISSN | 0030-1558 |
| 言語 | 日本語 |
| 著作権者 | Copyright (c) 2015 岡山医学会 |
| 論文のバージョン | publisher |
| DOI | 10.4044/joma.127.187 |
| NAID | 130005116819 |
| JaLCDOI | 10.18926/AMO/53674 |
|---|---|
| フルテキストURL | 69_5_279.pdf |
| 著者 | Saito, Yukie| Fujii, Yousuke| Yashiro, Masato| Tsuge, Mitsuru| Nosaka, Nobuyuki| Yamashita, Nobuko| Yamada, Mutsuko| Tsukahara, Hirokazu| Morishima, Tsuneo| |
| 抄録 | Lung hyperpermeability affects the development of acute respiratory distress syndrome (ARDS), but therapeutic strategies for the control of microvascular permeability have not been established. We examined the effects of edaravone, dexamethasone, and N-monomethyl-L-arginine (L-NMMA) on permeability changes in human pulmonary microvascular endothelial cells (PMVEC) under a hypercytokinemic state. Human PMVEC were seeded in a Boyden chamber. After monolayer confluence was achieved, the culture media were replaced respectively by culture media containing edaravone, dexamethasone, and L-NMMA. After 24-h incubation, the monolayer was stimulated with tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). Fluorescein-labeled dextran was added. Then the trans-human PMVEC leak was measured. Expressions of vascular endothelial-cadherin (VE-cadherin) and zonula occludens-1 protein (ZO-1) were evaluated using real-time quantitative polymerase chain reaction and immunofluorescence microscopy. The results showed that TNF-α＋IL-1β markedly increased pulmonary microvascular permeability. Pretreatment with edaravone, dexamethasone, or L-NMMA attenuated the hyperpermeability and inhibited the cytokine-induced reduction of VE-cadherin expression on immunofluorescence staining. Edaravone and dexamethasone increased the expression of ZO-1 at both the mRNA and protein levels. Edaravone and dexamethasone inhibited the permeability changes of human PMVEC, at least partly through an enhancement of VE-cadherin. Collectively, these results suggest a potential therapeutic approach for intervention in patients with ARDS. |
| キーワード | pulmonary microvascular endothelial cells permeability edaravone vascular endothelial-cadherin zonula occludens-1 protein |
| Amo Type | Original Article |
| 出版物タイトル | Acta Medica Okayama |
| 発行日 | 2015-10 |
| 巻 | 69巻 |
| 号 | 5号 |
| 出版者 | Okayama University Medical School |
| 開始ページ | 279 |
| 終了ページ | 290 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| 資料タイプ | 学術雑誌論文 |
| 言語 | 英語 |
| 著作権者 | CopyrightⒸ 2015 by Okayama University Medical School |
| 論文のバージョン | publisher |
| 査読 | 有り |
| PubMed ID | 26490025 |
| Web of Science KeyUT | 000365519600004 |
| 著者 | 八代 将登| 塚原 宏一| 松川 昭博| 山田 睦子| 藤井 洋輔| 長岡 義晴| 津下 充| 山下 信子| 伊藤 利洋| 山田 雅夫| 増谷 弘| 淀井 淳司| 森島 恒雄| |
|---|---|
| 発行日 | 2013-08-01 |
| 出版物タイトル | 岡山医学会雑誌 |
| 巻 | 125巻 |
| 号 | 2号 |
| 資料タイプ | 学術雑誌論文 |