脳のシスタチオニン 第Ⅱ編 大脳組織呼吸（in vitro）に及ぼすL-シスタチオニンの影響

in vitroにおけるラッテの脳及び肝組織呼吸に及ぼすL-シスタチオニンの影響を見た.脳切片及びホモジネートではシスタチオニンはその酸素消費量を殆んど変化せしめず,又,ブドー糖の呼吸率にも見るべき影響を与えない.これに反して肝切片では著明な呼吸率の上昇を認めた.

The tissue respiration was investigated using slices and homogenates of brain cortex and liver of albino rats in K. R. P. solution with L-cystathionine as substrate. No significant increase of oxygen consumption of brain cortex followed the adding of L-cystathionine to K. R. P. solution, while considerable augmentation of that was found in liver tissue under same condition. And, L-cystathionine could activate the oxygen uptake of brain cortex neither when it was added to medium containing glucose as substrate previously. The results of these experiments suggest, therefore, that the cystathionine found in the human brain is not able to work as one of energy supports of brain like as glutamic acid.