result 8446 件
| JaLCDOI | 10.18926/AMO/54592 |
|---|---|
| FullText URL | 70_5_345.pdf |
| Author | Maruyama, Hidehiko| Nakata, Yusei| Kanazawa, Akane| Kikkawa, Kiyoshi| |
| Abstract | We sought to clarify the survival and neurodevelopmental outcomes of very low birth weight infants (VLBWIs) and to identify risk factors for death or neurodevelopmental impairment (NDI) in VLBWIs at our hospital. The total study population was 217 infants born in 2005-2012 weighing ≤1,500 g. We compared their outcomes with those from previous reports analyzed the causes of death. Risk factors for death after discharge or NDI were evaluated by a multivariate logistic regression analysis. The incidences of death or NDI reported revealed in this study and the database of Neonatal Research Network of Japan were 25.3% and 19.6% (p＝0.039), respectively. The main causes of death before discharge were intraventricular hemorrhage, sepsis, and persistent pulmonary hypertension of the newborn. The significant risk factors for death after discharge or NDI were early gestational age (weeks) and periventricular leukomalacia (adjusted odds ratio [95% confidence interval, p-value], 0.72 [0.54-0.94, 0.017] and 6.90 [1.35-38.25, 0.021], respectively). These factors must be addressed in order to improve treatment strategies for VLBWIs. |
| Keywords | intraventricular hemorrhage periventricular leukomalacia persistent pulmonary hypertension of the newborn sepsis very low birth weight infants |
| Amo Type | Original Articles |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-10 |
| Volume | volume70 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 345 |
| End Page | 352 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27777426 |
| Web of Science KeyUT | 000388098700003 |
| JaLCDOI | 10.18926/AMO/54590 |
|---|---|
| FullText URL | 70_5_331.pdf |
| Author | Iida, Atsuyoshi| Nosaka, Nobuyuki| Yumoto, Tetsuya| Knaup, Emily| Naito, Hiromichi| Nishiyama, Chihiro| Yamakawa, Yasuaki| Tsukahara, Kohei| Terado, Michihisa| Sato, Keiji| Ugawa, Toyomu| Nakao, Atsunori| |
| Abstract | In recent years, it has become evident that molecular hydrogen is a particularyl effective treatment for various disease models such as ischemia-reperfusion injury; as a result, research on hydrogen has progressed rapidly. Hydrogen has been shown to be effective not only through intake as a gas, but also as a liquid medication taken orally, intravenously, or locally. Hydrogenʼs effectiveness is thus multifaceted. Herein we review the recent research on hydrogen-rich water, and we examine the possibilities for its clinical application. Now that hydrogen is in the limelight as a gaseous signaling molecule due to its potential ability to inhibit oxidative stress signaling, new research developments are highly anticipated. |
| Keywords | hydrogen antioxidant effect medical gas gaseous signaling molecule clinical tests |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-10 |
| Volume | volume70 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 331 |
| End Page | 337 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27777424 |
| Web of Science KeyUT | 000388098700001 |
| Author | Fukuoka, Takanori| Kato, Sadahisa| |
|---|---|
| Published Date | 2016-06-28 |
| Publication Title | NOVATECH 2016 Proceedings |
| Content Type | Conference Paper |
| Author | Ohtsuki, Takashi| Miki, Shunya| Kobayashi, Shouhei| Haraguchi, Tokuko| Nakata, Eiji| Hirakawa, Kazutaka| Sumita, Kensuke| Watanabe, Kazunori| Okazaki, Shigetoshi| |
|---|---|
| Published Date | 2015-12 |
| Publication Title | Scientific Reports |
| Volume | volume5 |
| Content Type | Journal Article |
| Author | Ohtsuki, Takashi| Kanzaki, Shigeto| Nishimura, Sae| Kunihiro, Yoshio| Sisido, Masahiko| Watanabe, Kazunori| |
|---|---|
| Published Date | 2016-08 |
| Publication Title | Nature Communications |
| Volume | volume7 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/54544 |
|---|---|
| Title Alternative | Factor Analysis of Learning Outcomes and Strain of Undergraduate Students |
| FullText URL | bhe_011_163_182.pdf |
| Author | 岡田 典子| |
| Abstract | 高等教育の質保証時代において，各大学のアカウンタビリティー（説明責任）とアウトカム（成果）が求められている。本研究では，アウトプットに学習と情緒の両側面を組み込んだ分析モデルに基づいて質問紙調査を行い，学習成果とストレインの要因分析を行った。分析の結果，＜学習成果＞の因子である「汎用的能力」と「知識・技能」では規定要因が異なること，学習成果は大学入学後の早い時期から分化していることが明らかになり，その背景にはディスポジション（disposition）があると示唆される。また，＜ストレイン＞の因子である「不快・未充足」と「緊張・心配」には，現在の悩みごとだけではなく，キャリア形成科目の履修が有意な影響を及ぼしていることが明らかになった。 |
| Keywords | 教育効果 学習成果 ストレイン ディスポジション キャリア教育 |
| Publication Title | Bulletin of Higher Education Okayama University |
| Published Date | 2015-12-30 |
| Volume | volume11 |
| Start Page | 163 |
| End Page | 182 |
| ISSN | 1881-5952 |
| language | Japanese |
| File Version | publisher |
| NAID | 120005838022 |
| JaLCDOI | 10.18926/AMO/54506 |
|---|---|
| FullText URL | 70_4_291.pdf |
| Author | Yoshioka, Norie| Shimo, Tsuyoshi| Ibaragi, Soichiro| Sasaki, Akira| |
| Abstract | Temporomandibular joint (TMJ) dislocation can occur during daily activities and negatively affect a patientʼs quality of life. Although both nonsurgical and surgical techniques have been used to treat recurrent TMJ dislocation, the former is not always successful and the latter, although having a high success rate, is invasive and requires hospitalization. Recently, autologous blood injection has been used to treat recurrent TMJ dislocation. However, this technique is not yet widely used in clinical practice. We designed this study to obtain further information as to efficacy, safety and stability of autologous blood injection for recurrent TMJ dislocation. |
| Keywords | autologous blood injection recurrent temporomandibular joint dislocation |
| Amo Type | Clinical Study Protocols |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 291 |
| End Page | 294 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549675 |
| Web of Science KeyUT | 000384748600010 |
| JaLCDOI | 10.18926/AMO/54503 |
|---|---|
| FullText URL | 70_4_273.pdf |
| Author | Makimoto, Go| Miyahara, Nobuaki| Yoshikawa, Mao| Taniguchi, Akihiko| Kanehiro, Arihiko| Tanimoto, Mitsune| Kiura, Katsuyuki| |
| Abstract | Heerfordtʼs syndrome is a rare manifestation of sarcoidosis and is defined as a combination of facial palsy, parotid swelling, and uveitis, associated with a low-grade fever. We report a case of Heerfordtʼs syndrome presenting with a high fever and increased serum tumor necrosis factor alpha (TNF-α) levels. The patient had facial palsy, parotid swelling, uveitis, and swelling of the right supraclavicular and hilar lymph nodes. Corticosteroid therapy was initiated, and her symptoms soon resolved completely, in tandem with a decrease in TNF-α serum levels. |
| Keywords | Heerfordtʼs syndrome sarcoidosis TNF-α |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 273 |
| End Page | 277 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549672 |
| Web of Science KeyUT | 000384748600007 |
| JaLCDOI | 10.18926/AMO/54502 |
|---|---|
| FullText URL | 70_4_269.pdf |
| Author | Takeuchi, Miharu| Maruyama, Hidehiko| Oura, Naoko| Kanazawa, Akane| Nakata, Yusei| Minami, Susumu| Kikkawa, Kiyoshi| |
| Abstract | Twin anemia-polycythemia sequence (TAPS) is a group of disorders in monochorionic twins characterized by a large intertwin hemoglobin difference without amniotic fluid discordance. Reticulocyte count is used to diagnose this condition, but little is known about the role of erythroblasts, which are the prior stage of reticulocytes. In the present case of TAPS, the 25-yr-old Japanese mother showed no signs of oligohydramnios or polyhydramnios throughout gestation. The twins were born at 36 weeks and 6 days, weighing 2,648g and 1,994g. The intertwin hemoglobin difference in umbilical cord blood was (21.1－5.0＝) 16.1g/dL and the donor twin showed signs of chronic anemia, including myocardial hypertrophy and pericardial effusion. Erythroblastosis of the donor twin was prolonged (53,088.5, 42,114.8 and 44,217.9/μL on days 0, 1 and 2, respectively). Erythroblastosis, which indicates chronic anemia, is also a good diagnostic indicator of TAPS. |
| Keywords | anastomosis erythroblast monochorionic diamniotic twin reticulocyte twin anemia-polycythemia sequence |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 269 |
| End Page | 272 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549671 |
| Web of Science KeyUT | 000384748600006 |
| JaLCDOI | 10.18926/AMO/54500 |
|---|---|
| FullText URL | 70_4_255.pdf |
| Author | Nosaka, Nobuyuki| Fujiwara, Takeo| Knaup, Emily| Okada, Ayumi| Tsukahara, Hirokazu| |
| Abstract | Estimation methods for pediatric weight have not been evaluated for Japanese children. This study aimed to assess the accuracy of mothersʼ reports of their childrenʼs weight in Japan. We also evaluated potential alternatives to the estimation of weight, including the Broselow tape (BT), Advanced Pediatric Life Support (APLS), and Parkʼs formulae. We prospectively collected cross-sectional data on a convenience sample of 237 children aged less than 10 years who presented to a general pediatric outpatient clinic with their mothers. Each weight estimation method was evaluated using Bland-Altman plots and by calculating the proportion within 10 and 20 of the measured weight. Mothersʼ reports of weight were the most accurate method, with 94.9 within 10 of the measured weight, the lowest mean difference (0.27kg), and the shortest 95 limit of agreement (－1.4 to 1.9kg). The BT was the most reliable alternative, followed by APLS and Parkʼs formulae. Mothersʼ reports of their children ʼs weight are more accurate than other weight estimation methods. When no report of a childʼs weight by the mother is available, BT is the best alternative. When an aged-based formula is the only option, the APLS formula is preferred. |
| Keywords | body weight child estimation techniques mothers, parents |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 255 |
| End Page | 259 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549669 |
| Web of Science KeyUT | 000384748600004 |
| JaLCDOI | 10.18926/AMO/54499 |
|---|---|
| FullText URL | 70_4_243.pdf |
| Author | Osawa, Masahiro| Ohashi, Kadoaki| Kubo, Toshio| Ichihara, Eiki| Takata, Saburo| Takigawa, Nagio| Takata , Minoru| Tanimoto, Mitsune| Kiura, Katsuyuki| |
| Abstract | Vandetanib (ZactimaTM) is a novel, orally available inhibitor of both vascular endothelial growth factor receptor-2 (VEGFR-2) and epidermal growth factor receptor (EGFR) tyrosine kinase. In the present study, a line of transgenic mice with a mouse Egfr gene mutation (delE748-A752) corresponding to a human EGFR mutation (delE746-A750) was established. The transgenic mice developed atypical adenomatous hyperplasia to adenocarcinoma of the lung at around 5 weeks of age and died of lung tumors at approximately 17 weeks of age. In the mice treated with vandetanib (6mg/kg/day), these lung tumors disappeared and the phosphorylations of EGFR and VEGFR-2 were reduced in lung tissues to levels comparable to those of non-transgenic control mice. The median overall survival time of the transgenic mice was 28 weeks in the vandetanib-treated group and 17 weeks in the vehicle-treated group. Vandetanib significantly prolonged the survival of the transgenic mice (log-rank test, p＜0.01); resistance to vandetanib occurred at 20 weeks of age and the animals died from their lung tumors at about 28 weeks of age. These data suggest that vandetanib could suppress the progression of tumors harboring an activating EGFR mutation. |
| Keywords | vandetanib VEGFR EGFR nonsmall cell lung cancer transgenic mouse |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 243 |
| End Page | 253 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549668 |
| Web of Science KeyUT | 000384748600003 |
| JaLCDOI | 10.18926/OER/54475 |
|---|---|
| Title Alternative | An Interview Transcript on GaN Research History with Dr. Herbert Paul Maruska (1) |
| FullText URL | oer_048_1_061_077.pdf |
| Author | Fujii, Daiji| |
| Publication Title | Okayama Economic Review |
| Published Date | 2016-07-15 |
| Volume | volume48 |
| Issue | issue1 |
| Start Page | 61 |
| End Page | 77 |
| ISSN | 0386-3069 |
| language | Japanese |
| Copyright Holders | Copyright © 2016 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120005822609 |
| Title Alternative | Drug interaction (36. Combination with oral molecular target drugs in lung cancer) |
|---|---|
| FullText URL | 128_141.pdf |
| Author | Higashionna, Tsukasa| Esumi, Satoru| Kitamura, Yoshihisa| Sendo, Toshiaki| |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2016-08-01 |
| Volume | volume128 |
| Issue | issue2 |
| Start Page | 141 |
| End Page | 146 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.128.141 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2016 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.128.141 |
| NAID | 130005262644 |
| Title Alternative | The effectiveness of team-based learning (TBL) as a new teaching approach |
|---|---|
| FullText URL | 128_125.pdf |
| Author | Suno, Manabu| |
| Keywords | アクティブラーニング（active learning） チーム基盤型学習（team-based learning） 問題基盤型学習（problem-based learning） |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2016-08-01 |
| Volume | volume128 |
| Issue | issue2 |
| Start Page | 125 |
| End Page | 128 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.128.125 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2016 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.128.125 |
| NAID | 130005262530 |
| FullText URL | IEEE_ICME2016_MMCloudCity_W136.pdf |
|---|---|
| Author | Hara, Sunao| Kobayashi, Shota| Abe, Masanobu| |
| Keywords | Environmental sound Crowdsourcing Loudness Crowdedness Smart City |
| Note | Copyright © 2016 IEEE. Reprinted from EEE ICME Workshop on Multimedia Mobile Cloud for Smart City Applications (MMCloudCity-2016). This material is posted here with permission of the IEEE. Permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution must be obtained from the IEEE by writing to pubs-permissions@ieee.org. By choosing to view this document, you agree to all provisions of the copyright laws protecting it.| |
| Published Date | 2016-07 |
| Publication Title | IEEE ICME Workshop on Multimedia Mobile Cloud for Smart City Applications (MMCloudCity-2016) |
| Content Type | Conference Paper |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | Copyright © 2016 IEEE. |
| File Version | author |
| Official Url | http://icme2016.org/| |
| Title Alternative | Incisional hernia repair after wide excision of the iliac bone |
|---|---|
| FullText URL | 128_117.pdf |
| Author | Tsukuda, Kazunori| Asano, Hiroaki| Mandai, Yasuhiro| Fujiwara, Toshiyoshi| |
| Abstract | The patient was a 46-year old Japanese female who had undergone wide excision of the iliac bone and hip transposition at our institute's orthopedics department 2 years earlier. She presented with a growing incisional hernia and was transferred to our gastroenterological surgery department for surgical treatment. We planned a mesh repair for the incisional hernia, which protruded over the right iliac bone. The dimensions of the abdominal defect were 15×9 cm, and we used prolene mesh to repair the defect. The mesh was fixed at the inner part of the iliac bone, folded back at the iliac horn and fixed to the abdominal oblique muscles. The postoperative course was smooth, and recurrence was not seen at 3.5 years after the operation. An incisional hernia as seen in this patient's case is very rare, but we found that the underlay technique and prolene mesh were very useful for the three-dimensional hernia repair. |
| Keywords | 腹壁瘢痕ヘルニア（incisional hernia） 腸骨軟骨肉腫（chondrosarcoma of the iliac bone） 腸骨広範囲切除術（wide excision of the iliac bone） プロリーンメッシュ（prolene mesh） |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2016-08-01 |
| Volume | volume128 |
| Issue | issue2 |
| Start Page | 117 |
| End Page | 120 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.128.117 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2016 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.128.117 |
| NAID | 130005262528 |
| Title Alternative | Magnified observation of spontaneous morphological changes of duodenal follicular lymphoma |
|---|---|
| FullText URL | 128_111.pdf |
| Author | Iwamuro, Masaya| Takata, Katsuyoshi| Kawano, Seiji| Kawahara, Yoshiro| Yoshino, Tadashi| Okada, Hiroyuki| |
| Abstract | A 63-year-old Japanese woman was diagnosed with duodenal follicular lymphoma. The initial esophagogastroduodenoscopic examination with magnifying observation revealed opaque white spots and enlarged whitish villi. Nine months later, esophagogastroduodenoscopy showed that the size of the lymphoma lesion decreased, and only opaque white spots were visible. The histological analysis of biopsy samples obtained during the initial endoscopy examination showed both neoplastic follicles and an inter-follicular infiltration of lymphoma cells, whereas the biopsy samples obtained at the endoscopy performed 9 months later showed only neoplastic follicle formation. These results suggest that the magnifying endoscopic features may reflect the underlying pathological mechanisms : enlarged whitish villi are probably due to lymphoma cell infiltration in the inter-follicular area, and opaque white spots are probably caused by neoplastic follicle formation. |
| Keywords | 消化管原発濾胞性リンパ腫（primary gastrointestinal follicular lymphoma） 悪性リンパ腫（malignant lymphoma） 拡大内視鏡検査（magnifying endoscopy） |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2016-08-01 |
| Volume | volume128 |
| Issue | issue2 |
| Start Page | 111 |
| End Page | 116 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.128.111 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2016 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.128.111 |
| NAID | 130005262531 |
| Title Alternative | Identification of the adipokine ‘vaspin’ and its significance in metabolic syndrome |
|---|---|
| FullText URL | 128_103.pdf |
| Author | Wada, Jun| |
| Keywords | metabolic syndrome adipokine atherosclerosis endothelial cells apoptosis |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2016-08-01 |
| Volume | volume128 |
| Issue | issue2 |
| Start Page | 103 |
| End Page | 109 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.128.103 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2016 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.128.103 |
| NAID | 130005262534 |
| Title Alternative | The 2015 Incentive Award of the Okayama Medical Association in Cancer Research (2015 Hayashibara Prize and Yamada Prize) |
|---|---|
| FullText URL | 128_99.pdf |
| Author | Dansako, Hiromichi| |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2016-08-01 |
| Volume | volume128 |
| Issue | issue2 |
| Start Page | 99 |
| End Page | 102 |
| ISSN | 0030-1558 |
| Related Url | https://doi.org/10.4044/joma.128.99 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2016 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.128.99 |
| NAID | 130005262636 |
| Title Alternative | The 2015 Incentive Award of the Okayama Medical Association in Neuroscience (2015 Niimi Prize) |
|---|---|
| FullText URL | 128_95.pdf |
| Author | Toyoshima, Atsuhiko| |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2016-08-01 |
| Volume | volume128 |
| Issue | issue2 |
| Start Page | 95 |
| End Page | 97 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf http://doi.org/10.4044/joma.128.95 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2016 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.128.95 |
| NAID | 130005262637 |
