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Author La Rocca, Romain| Tsai, Pi-Cheng| Kato, Koji| Nakajima, Yoshiki| Akita, Fusamichi| Shen, Jian-Ren|
Keywords Photosystem I Light harvesting Fucoxanthin-chlorophyll a/c binding proteins Haptophytes Cryo-EM
Published Date 2026-08
Publication Title Biochimica et Biophysica Acta (BBA) - Bioenergetics
Volume volume1867
Issue issue3
Publisher Elsevier BV
Start Page 149588
ISSN 0005-2728
NCID AA00564646
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Authors.
File Version publisher
PubMed ID 41864554
DOI 10.1016/j.bbabio.2026.149588
Web of Science KeyUT 001729306400001
Related Url isVersionOf https://doi.org/10.1016/j.bbabio.2026.149588
JaLCDOI 10.18926/AMO/70457
FullText URL 80_2_147.pdf
Author Sakamoto, Shinya| Tabuchi, Motoyasu| Hamada, Akira| Yoshimatsu, Rika| Saisaka, Yuichi| Matsumoto, Manabu| Iwata, Jun| Okabayashi, Takehiro|
Abstract Common bile duct (CBD) injury after blunt abdominal trauma is rare and difficult to diagnose. Delayed recognition leads to severe morbidity. A 70-year-old Japanese man was admitted after sustaining blunt abdominal trauma. Ultrasonography revealed intra-abdominal fluid, suggesting bleeding. Contrast-enhanced computed tomography revealed pancreatic head injury, intra-abdominal bleeding, and pseudoaneurysm of the anterior superior pancreatoduodenal artery (ASPDA). Bile duct injury was not evident. The application of transarterial embolization (TAE) controlled the bleeding. Canulation into the pancreatic or biliary duct was not possible during endoscopic retrograde cholangiopancreatography. An emergency laparotomy revealed severe pancreatic head and extrahepatic bile duct injuries. Pancreaticoduodenectomy/Child reconstruction was performed. Complete CBD transection was confirmed. The patient was ultimately discharged without complications. Early recognition, timely surgical management, and intensive care are essential for favorable outcomes in patients who have sustained abdominal trauma.
Keywords blunt abdominal trauma intensive care emergency laparotomy pancreatoduodenectomy
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2026-04
Volume volume80
Issue issue2
Publisher Okayama University Medical School
Start Page 147
End Page 152
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/70456
FullText URL 80_2_141.pdf
Author Sakamoto-Tokunaga, Moe| Katsuyama, Takayuki| Matoba, Masaki| Tamura, Tomokazu| Kubota, Natsuki| Terajima, Yuya| Shidahara, Kenta| Hirose, Kei| Matsumoto, Kazuya| Nawachi, Shoichi| Nakadoi, Takato| Katayama, Yu| Hayashi, Keigo| Miyawaki, Yoshia| Katsuyama, Eri| Watanabe, Haruki| Takano-Narazaki, Mariko| Matsumoto, Yoshinori| Sada, Ken-Ei| Tsuji, Shuma| Gotoh, Kazuyoshi| Fukushima, Shinnosuke| Hagiya, Hideharu| Wada, Jun|
Abstract VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory somatic) syndrome has a poor prognosis, with infections being a major cause of death. Raoultella ornithinolytica is an environmental bacterium found predominantly in soil and water. Although R. ornithinolytica can cause various infections, necrotizing fasciitis due to this bacterium has not been reported. We describe the case of an 84-year-old Japanese male with VEXAS syndrome who developed septic shock and necrotizing fasciitis while he was under immunosuppressive therapy. The pathogen was initially misidentified as R. planticola by mass spectrometry but later confirmed by whole-genome sequencing as extended spectrum β-lactamase (ESBL) produced by R. ornithinolytica. Although a life-saving leg amputation was required, the patient recovered with appropriate antibiotic therapy. R. ornithinolytica is thus able to cause severe skin infections in immunocompromised individuals.
Keywords necrotizing fasciitis Raoultella ornithinolytica VEXAS syndrome whole-genome sequence
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2026-04
Volume volume80
Issue issue2
Publisher Okayama University Medical School
Start Page 141
End Page 145
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/70455
FullText URL 80_2_131.pdf
Author Nakata, Shunsuke| Takatsu, Fumiaki| Mikuriya, Yoshihiro| Kakishita, Tomokazu| Hato, Shinji| Ohta, Koji| Kobatake, Takaya|
Abstract Colorectal surgery is associated with a high incidence of postoperative complications regardless of the advances in surgical techniques and multidisciplinary treatment. Proteinuria is common in patients with malignancies, but few studies have investigated the association between preoperative proteinuria and patient prognoses, especially postoperative complications. We investigated the impact of proteinuria on patients undergoing colorectal surgery in a single-center, retrospective cohort study of 767 patients who underwent surgical resection for colorectal cancer between January 2016 and December 2022 at the National Hospital Organization Shikoku Cancer Center. Among them, 81 patients with preoperative proteinuria were compared with the control group of 686 patients without proteinuria. Our analyses revealed that the patients with proteinuria had malnutrition with a significantly lower prognostic nutritional index compared to the no-proteinuria control group (p<0.001). The proteinuria group had a significantly advanced tumor stage (p=0.005), experienced more bleeding during the surgery (p=0.002), and required more transfusions (p<0.001). Postoperative complications were significantly more frequent in the proteinuria group (p=0.03), thus demonstrating that proteinuria was independently associated with postoperative complications (p=0.045). Proteinuria in patients undergoing colorectal cancer surgery can therefore be considered a risk factor for postoperative complications.
Keywords colorectal cancer surgery proteinuria complication malnutrition
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-04
Volume volume80
Issue issue2
Publisher Okayama University Medical School
Start Page 131
End Page 139
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/70454
FullText URL 80_2_119.pdf
Author Ikuma, Hisanori| Hirose, Tomohiko| Kawasaki, Keisuke| Otsuka, Kazutoshi|
Abstract We evaluated the clinical outcomes and limitations of anterior and posterior combined surgery with a mini-open corpectomy applying an expandable cage (Xcore®) and percutaneous pedicle screw (PPS) fixation using single-position surgery in the lateral decubitus position in patients aged > 75 years with thoracolumbar vertebral collapse. The cases of 30 consecutive patients who underwent this procedure and had ≥ 1-year follow-up were retrospectively analyzed. The mean operative time was 78.8 min and the estimated blood loss was 115.7 ml per level. The complications included adjacent junctional failure (n=9, 30%), deep venous thrombosis (n=3, 10%), delirium (n=3, 10%), pleural injury (n=2, 6%), screw backout (n=1, 3%) kidney injury (n=1, 3%), chylothorax (n=1, 3%), and wound dehiscence (n=1, 3%). Seven cases (23.3%) required reoperation. Local kyphosis showed significant improvement (p<0.05) that was maintained at the final follow-up. The Japanese Orthopaedic Association Back Pain Evaluation Questionnaire and a visual analogue scale indicated significant improvement in all categories at the final follow-up (p<0.05). The use of mini-open corpectomy and posterior fixation with SPAPS can thus provide reliable radiological correction and good postoperative clinical outcomes even in patients aged > 75 years. However, a limitation of this procedure is the rate of reoperation (23.3%) for osteoporosis-related adjacent segment fracture and screw backout.
Keywords single postion surgery osteoporotic vertebral collapse anterior and posterior combined surgery minimum invasive surgery
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-04
Volume volume80
Issue issue2
Publisher Okayama University Medical School
Start Page 119
End Page 129
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/70452
FullText URL 80_2_099.pdf
Author Nguyen Trung Thanh| Nakamichi, Ryo| Shimamura, Yasunori| Saito, Taichi| Ishihara, Takeshi| Furutani, Tomoki| Shitozawa, Hisakazu| Noda, Tomoyuki| Ozaki, Toshifumi|
Abstract Although the performance of minimally invasive plate osteosynthesis (MIPO) via the anteroinferior approach is increasingly adopted for midshaft clavicle fractures, the influence of fracture morphology on clinical outcomes under a standardized protocol is unclear. We retrospectively analyzed the cases of 54 patients who underwent anteroinferior MIPO for an acute midshaft clavicle fracture (AO/OTA types B1, B2, B3) performed by a single surgeon across three affiliated institutions (2009-2022). We evaluated the clinical outcomes, i.e., the surgical time, incision length, radiographic union, reduction accuracy, range of motion, pain (visual analog scale [VAS]), and complications and compared them among the three AO/OTA subtypes. The mean incision length (3.4 cm) and surgical time (71-79 min) were similar among the groups (both p>0.2). All fractures achieved radiographic union at a mean of 3.5 months. Postoperative alignment and clavicular length were maintained (length reduction −1.0±2.2 mm [B1], −0.5±2.0 mm [B2], −0.6±1.8 mm [B3]; p=0.825; angulation −0.8±3.4°, −1.1±3.1°, −0.3±3.3°; p=0.888). At 3 months, shoulder elevation and abduction were 169°-175° (p=0.079) and 164°-175° (p=0.324). Pain was minimal (100-mm VAS: ≤1 mm; p=0.782). One plate-fatigue failure occurred; no supraclavicular-nerve symptoms were recorded. Anteroinferior MIPO yielded consistent outcomes across AO/OTA types, with excellent union rates, functional recovery, and few complications, indicating that this technique is safe and reproducible for the surgical management of midshaft clavicle fractures.
Keywords clavicle fracture minimally invasive plate osteosynthesis anteroinferior plating AO/OTA classification
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-04
Volume volume80
Issue issue2
Publisher Okayama University Medical School
Start Page 99
End Page 107
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/70450
FullText URL 80_2_075.pdf
Author Lin, Deting| Horita, Masahiro| Watanabe, Masahito| Hasei, Joe| Ohtsuki, Takashi| Otsuka, Noriaki| Ichikawa, Chinatsu| Shimizu, Noriyuki| Naniwa, Shuichi| Ozaki, Toshifumi| Nishida, Keiichiro|
Abstract A disintegrin and metalloproteinase 12 (ADAM12) is known to be involved in chondrocyte proliferation and is upregulated in the synovial tissue of osteoarthritis (OA). However, the underlying mechanisms of ADAM12 on rheumatoid arthritis (RA) synovial cell proliferation remain unknown. Here, we investigated the role of ADAM12 in the proliferation of RA synovial fibroblasts (RASFs). The expression and localization of ADAM12 in RA synovial tissues were examined by immunohistochemistry and compared with OA and healthy control (HC) synovial tissues. The effect of inflammatory cytokines (TNF-α, TGF-β1, and PDGF-BB) on ADAM12 expression in RASFs from RA patients was examined by real-time RT-PCR. The effect of ADAM12 knock-down by ADAM12 siRNA and ADAM12 overexpression on cell proliferation of RASFs were examined by WST-1 assay. ADAM12 was identified predominantly in RA synovial tissue rather than OA and HC synovial tissues. Stimulation with TGF-β1 upregulated the expression of ADAM12 and cell proliferation of RASFs. ADAM12 siRNA suppressed TGF-β1-induced cell proliferation of RASFs, while ADAM12 overexpression promoted the cell proliferation of RASFs. These findings demonstrate that ADAM12 may have a key role in TGF-β1-induced cell proliferation of synovial fibroblasts in patients with RA.
Keywords rheumatoid arthritis synovial tissue TGF-β1 ADAM12 cell proliferation
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-04
Volume volume80
Issue issue2
Publisher Okayama University Medical School
Start Page 75
End Page 83
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
FullText URL fulltext.pdf
Author Hatvani, Lóránt| Hisano, Sakae| Kondo, Hideki| Sugahara, Hitomi| Telengech, Paul| Shahi, Sabitree| Ibiang, Sarah Remi| Kocsubé, Sándor| Kartali, Tünde| Fitzpatrick, David A.| Grogan, Helen| Suzuki, Nobuhiro|
Keywords Lecanicillium fungicola Agaricus bisporus Akanthomyces Simplicillium dsRNA Myovirus Fungal virus Mycovirgaviridae Partitiviridae Polymycoviridae Botourmiaviridae Splipalmiviridae Narna-like virus
Published Date 2026-05
Publication Title Virus Research
Volume volume367
Publisher Elsevier BV
Start Page 199714
ISSN 0168-1702
NCID AA10642076
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Author(s).
File Version publisher
PubMed ID 41856379
DOI 10.1016/j.virusres.2026.199714
Web of Science KeyUT 001734178800001
Related Url isVersionOf https://doi.org/10.1016/j.virusres.2026.199714
FullText URL fulltext.pdf
Author Miyoshi, Kentaroh| Otani, Shinji| Sugimoto, Seiichiro| Tanaka, Shin| Okazaki, Mikio| Toyooka, Shinichi|
Keywords Anti-thymocyte globulin Acute antibody-mediated rejection Treatment Lung transplantation
Published Date 2026-05
Publication Title Respiratory Investigation
Volume volume64
Issue issue3
Publisher Elsevier BV
Start Page 101428
ISSN 2212-5345
NCID AA12579673
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Authors.
File Version publisher
DOI 10.1016/j.resinv.2026.101428
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Author Ishizaki, Takuma| Hashida, Yoichi| Hirabayashi, Hideyuki| Sasaki, Kazuhiro| Tokunaga, Hiroki| Simon‐Ada, Eliza Vie M.| Wakayama, Masataka| Takai, Toshiyuki| Saito, Hiroki| Nagano, Atsushi J.| Sakakibara, Hitoshi| Kojima, Mikiko| Takebayashi, Yumiko| Kim, Sung‐Ryul| Matsushima, Ryo| Thomson, Michael J.| Sugimoto, Kazuhiko| Hibara, Ken‐Ichiro| Ishimaru, Tsutomu|
Keywords EARLY-MORNING FLOWERING 3 flower opening time heat stress rice seed setting rate
Published Date 2026-04-09
Publication Title Plant Biotechnology Journal
Publisher Wiley
ISSN 1467-7644
NCID AA11805223
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Author(s).
File Version publisher
PubMed ID 41954325
DOI 10.1111/pbi.70653
Related Url isVersionOf https://doi.org/10.1111/pbi.70653
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Author Ohara, Toshiaki| Iwasaki, Yoshiaki| Kasai, Tomonari| Yamashita, Toru| Komaki, Shiho| Hamada, Yusuke| Fujisawa, Masayoshi| Matsukawa, Akihiro|
Keywords Hypoxia-inducible factor Working memory Hippocampus Iron
Published Date 2026-03-02
Publication Title Scientific Reports
Volume volume16
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 11550
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2026 Scientific
File Version publisher
PubMed ID 41772141
DOI 10.1038/s41598-026-42296-3
Related Url isVersionOf https://doi.org/10.1038/s41598-026-42296-3
FullText URL fulltext.pdf
Author Monden, Naoyuki| Yabuguchi, Reo|
Published Date 2026-04-04
Publication Title Geometriae Dedicata
Volume volume220
Issue issue3
Publisher Springer Science and Business Media LLC
Start Page 29
ISSN 0046-5755
NCID AA0065688X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2026
File Version publisher
DOI 10.1007/s10711-026-01079-w
Related Url isVersionOf https://doi.org/10.1007/s10711-026-01079-w
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Author Uegatani, Yusuke| Ishibashi, Ippo| Sakota, Aya|
Keywords Probability triangulation mathematical modelling theoretical inversion
Published Date 2026-04-01
Publication Title International Journal of Mathematical Education in Science and Technology
Publisher Informa UK Limited
ISSN 0020-739X
NCID AA00680498
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Author(s).
File Version publisher
DOI 10.1080/0020739x.2026.2648014
Related Url isVersionOf https://doi.org/10.1080/0020739x.2026.2648014
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Author Matsuda, Yoshihiro| Morizane, Shin| Takezaki, Daiki| Sakamoto, Yuma| Baba, Nobuyasu| Iseki, Masanori| Kawakami, Yoshio| Shiomi, Tatsushi| Mukai, Tomoyuki|
Keywords psoriasis obesity aerobic exercise imiquimod high-fat diet
Published Date 2026-02-28
Publication Title International Journal of Molecular Sciences
Volume volume27
Issue issue5
Publisher MDPI AG
Start Page 2308
ISSN 1422-0067
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 by the authors.
File Version publisher
PubMed ID 41828533
DOI 10.3390/ijms27052308
Web of Science KeyUT 001713645500001
Related Url isVersionOf https://doi.org/10.3390/ijms27052308
FullText URL fulltext.pdf
Author Yoshioka, Yuma| Miyaji, Takaaki|
Keywords zinc transporter 1 SLC30A1 zinc pH proteoliposome
Published Date 2026-02-21
Publication Title Biological and Pharmaceutical Bulletin
Volume volume49
Issue issue2
Publisher Pharmaceutical Society of Japan
Start Page 364
End Page 370
ISSN 0918-6158
NCID AA10885497
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Author(s).
File Version publisher
PubMed ID 41730615
DOI 10.1248/bpb.b25-00624
Web of Science KeyUT 001697164800001
Related Url isVersionOf https://doi.org/10.1248/bpb.b25-00624
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Author Leon, Elizabeth| Nakamura, Shin| Shindo, Satoru| Pastore, Maria Rita| Kumagai, Tomoki| Heidari, Alireza| Abdolahinia, Elaheh Dalir| Ueda, Tomoya| Memida, Takumi| Duran-Pinedo, Ana| Frias-Lopez, Jorge| Han, Xiaozhe| Chen, Xin| Huang, Shengyuan| Cao, Guoqin| Ruiz, Sunniva| Potempa, Jan| Kawai, Toshihisa|
Keywords Porphyromonas gingivalis outer membrane vesicle periodontitis pathogenesis macrophage polarization osteoclastogenesis OC/MΦ unit
Published Date 2026-01-14
Publication Title International Journal of Molecular Sciences
Volume volume27
Issue issue2
Publisher MDPI AG
Start Page 831
ISSN 1422-0067
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 by the authors.
File Version publisher
PubMed ID 41596482
DOI 10.3390/ijms27020831
Web of Science KeyUT 001670605700001
Related Url isVersionOf https://doi.org/10.3390/ijms27020831
FullText URL papyrus_031_42_49.pdf
Author 杉能 道明|
Abstract  VUCAの時代(※)を生き抜く子どもたちに必要な資質・能力の育成が喫緊の課題とされている。算数科では永年,「統合的・発展的に考える力」を育成すべき資質・能力の中核に置いてきた。この力はVUCAの時代にも通用する力であり,子どもが「自ら課題を見付け,自ら学び,自ら考える」(確かな学力、1996)原動力になる力であると考える。しかしながら,未だそれを十分達成することはできていない。それは,「統合的・発展的に考える力」を育成するシステムが示されておらず,プロセスが確立されていないからであると考える。
 3年後には新学習指導要領の告示が予想される今,改めて算数科で育成すべき資質・能力の中核である「統合的・発展的に考える力」の育成に焦点を当てる。6年「立体の体積」の学びを通して,「統合的・発展的に考える力」を育成するシステムを提案する。
※「VUCAの時代」…Volatility(変動性),Uncertainty(不確実性),Complexity(複雑性),Ambiguity(曖昧性)のある時代。
Keywords 数学的な見方・考え方 統合的・発展的に考える力 数学のよさ
Publication Title 岡山大学算数・数学教育学会誌 : パピルス
Published Date 2025-03-28
Volume volume31
Start Page 42
End Page 49
ISSN 1341-3155
language Japanese
File Version publisher
FullText URL papyrus_031_1_11.pdf
Author 大西 鈴香| 岡崎 正和|
Abstract  平成29年度告示の学習指導要領では,小学校算数科の目標を(1)知識及び技能,(2)思考力,判断力,表現力等,(3)学びに向かう力,人間性等の三本の柱に基づいて示している.特に(2)思考力,判断力,表現力等の内容として,「基本的な数量や図形の性質などを見出し統合的・発展的に考察する力」を養うと記述され,統合を通して子どもの考える力の向上が目指されている.
 本稿は,第 3 学年のわり算の等分除と包含除の問題を様々な視点から比較し,児童に統合する体験をさせることを目的としたものである.授業分析の結果,統合に関しては,等分除と包含除を統合するだけでなく,さらにかけ算とわり算を大きくかけ算とみて統合すること,つまり二重に統合する必要がある場合があり,かけ算の意味理解がこの場面の理解を助けるとともに,二重の統合に起因する学びの困難を指摘することができる.
Keywords 算数 わり算 統合 等分除 包含除 かけ算
Publication Title 岡山大学算数・数学教育学会誌 : パピルス
Published Date 2025-03-28
Volume volume31
Start Page 1
End Page 11
ISSN 1341-3155
language Japanese
File Version publisher
FullText URL papyrus_031_prelim.pdf
Author 中川 征樹|
Publication Title 岡山大学算数・数学教育学会誌 : パピルス
Published Date 2025-03-28
Volume volume31
ISSN 1341-3155
language Japanese
File Version publisher
FullText URL fulltext.pdf
Author Galib, Md. Asadulla Al| Zhao, Maoxiang| Nakamura, Toshiyuki| Nakamura, Yoshimasa| Hirai, Yoshihiko| Nakashima, Yoshitaka| Munemasa, Shintaro| Mori, Izumi C.| Murata, Yoshiyuki|
Keywords Apoplastic flow Salicylic acid Rice Salinity Trisodium-8-hydroxy-1,3,6-pyrenetrisulphonic acid
Published Date 2026-03-18
Publication Title Physiology and Molecular Biology of Plants
Publisher Springer Science and Business Media LLC
ISSN 0971-5894
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2026
File Version publisher
DOI 10.1007/s12298-026-01733-3
Web of Science KeyUT 001717248700001
Related Url isVersionOf https://doi.org/10.1007/s12298-026-01733-3