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Title Alternative Questionnaire survey of junior and mid-career otolaryngologists' attitudes towards clinical research
Author Uraguchi, Kensuke| Yorifuji, Takashi| Takao, Soshi| Sugaya, Akiko| Ando, Mizuo|
Abstract  Introduction : Clinical research is crucial for the advancement of medicine, but modern otolaryngologists' attitudes regarding clinical research have not been known. This study was conducted to survey the background, knowledge, and interest in clinical research among junior and mid-career otolaryngologists.
 Methods : A questionnaire survey was distributed to 34 otolaryngologists with ≤15 years' clinical experience working at Okayama University and its affiliated facilities. The respondents were divided into junior (non-specialists) and mid-career otolaryngologists (specialists) based on whether they were board-certified otolaryngologists. The survey assessed their background, understanding, and interest in clinical research.
 Results : Twenty-nine otolaryngologists (83%) responded (10 junior and 19 mid-career otolaryngologists). There was significant individual variation in their interest and knowledge of clinical research. However, approximately half of the respondents indicated that they were not interested in and/or had never engaged in clinical research.
 Conclusion : The data collected by this survey contribute to our understanding of the current state of clinical research engagement among junior and mid-career otolaryngologists, and they can serve as a basis for exploring future strategies to increase this engagement.
Keywords 臨床研究 (clinical research) 統計解析 (statistical analysis) ビッグデータ (bigdata) 質問紙調査 (questionnaire survey)
Publication Title Journal of Okayama Medical Association
Published Date 2025-04-01
Volume volume137
Issue issue1
Start Page 20
End Page 24
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.137.20
language Japanese
Copyright Holders Copyright (c) 2025 岡山医学会
File Version publisher
DOI 10.4044/joma.137.20
Title Alternative The potential and prospects of organ generation medicine
Author Mori, Munemasa|
Keywords organ generation regeneration bioengineering
Publication Title Journal of Okayama Medical Association
Published Date 2025-04-01
Volume volume137
Issue issue1
Start Page 15
End Page 19
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.137.15
language Japanese
Copyright Holders Copyright (c) 2025 岡山医学会
File Version publisher
DOI 10.4044/joma.137.15
JaLCDOI 10.18926/ESR/68676
Title Alternative Improved sedimentary layer model including the accretionary prism in the fore-arc region of the Ryukyu arc, Japan
FullText URL esr_031_001_015.pdf
Author KOMATSU, Masanao| URAKAMI, Sohei| OKAMOTO, Taro| TAKENAKA, Hiroshi|
Abstract  We combine the recent seismic reflection profiles to construct a new seismic velocity model of the sedimentary layer incorporating the accretionary prism along the Ryukyu trench. In constructing the new model, we refer to the zoning (ZONE1 to ZONE4) identified by Okamura et al. (2017, Tectonophys.). The construction process consists of the following steps: First, we digitize either unconformities or VP=4 to 5 km/s lines as the seismic basement, whichever is more clearly identifiable. Second, the digitized thickness data of the sedimentary layer from the reflection profiles are geometrically modeled and interpolated to make the three-dimensional structure model. Finally, we supplement the external region of the constructed 3-D sedimentary model using the J-SHIS model provided by the NIED to complete the velocity structure model in the entire Ryukyu arc. The main features of our model are as follows: In ZONE1, off Ishigaki-jima island, the thick sedimentary layer extends about 50 km wide from the Ryukyu trench. In ZONE2, off Miyako-jima island, the thinner layer compared to the other zones is found near the trench, with a thin sedimentary terrace covering the area behind it. In ZONE3, off Okinawa-jima island, the sedimentary layer deepens as it approaches the trench. In ZONE4, off Tokara islands, the deepest layer among all zones is identified. We then conduct 3-D finite-difference simulations of seismic wave propagation using the new and the previous models to confirm the improvement of the new model. In the simulations, the effects of the accretionary prism along the Ryukyu trench on the seismic wave propagation are clearly identified.
Keywords Sedimentary layer model Accretionary prism Ryukyu arc
Publication Title Okayama University Earth Science Report
Published Date 2025-03-31
Volume volume31
Issue issue1
Start Page 1
End Page 15
ISSN 1340-7414
language Japanese
Copyright Holders © 2025 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved
File Version publisher
Author Ozato, Toshiki| Kono, Yoshiyasu| Horiguchi, Shigeru| Tsutsumi, Koichiro| Yamamoto, Hideki| Hirasawa, Akira| Ennishi, Daisuke| Tomida, Shuta| Toyooka, Shinichi| Otsuka, Motoyuki|
Keywords Homologous recombination repair Small bowel adenocarcinoma Genome
Note © 2025 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Apr. 2026.|
Published Date 2025-05-02
Publication Title European Journal of Cancer
Volume volume220
Publisher Elsevier BV
Start Page 115401
ISSN 0959-8049
NCID AA1075407X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 Elsevier Ltd.
File Version author
PubMed ID 40188744
DOI 10.1016/j.ejca.2025.115401
Web of Science KeyUT 001465491700001
Related Url isVersionOf https://doi.org/10.1016/j.ejca.2025.115401
FullText URL fulltext.pdf
Author Shinaoka, Akira| Kimata, Yoshihiro|
Keywords Lymphedema Lymphatic function Lymph flow Chylothorax Chylous ascites,lymph velocity
Published Date 2025-04-24
Publication Title Scientific Reports
Volume volume15
Issue issue1
Publisher Nature Portfolio
Start Page 14323
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 40275043
DOI 10.1038/s41598-025-99416-8
Web of Science KeyUT 001475676100005
Related Url isVersionOf https://doi.org/10.1038/s41598-025-99416-8
FullText URL fulltext.pdf
Author Ando, Yushin| Kobo, Akinao| Niwa, Tatsuya| Yamakawa, Ayako| Konoma, Suzuna| Kobayashi, Yuki| Nureki, Osamu| Taguchi, Hideki| Itoh, Yuzuru| Chadani, Yuhei|
Published Date 2025-03-08
Publication Title Nature Communications
Volume volume16
Issue issue1
Publisher Nature Portfolio
Start Page 2323
ISSN 2041-1723
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 40057501
DOI 10.1038/s41467-025-57659-z
Web of Science KeyUT 001462675700032
Related Url isVersionOf https://doi.org/10.1038/s41467-025-57659-z
FullText URL fulltext.pdf
Author Kong, Dezheng| Funabiki, Nobuo| Fang, Shihao| Noprianto, Mitsuhiro| Okayasu, Mitsuhiro| Puspitaningayu, Pradini|
Keywords creep test Raspberry Pi dial gauge needle reading smart lighting
Published Date 2025-04-02
Publication Title Technologies
Volume volume13
Issue issue4
Publisher MDPI
Start Page 139
ISSN 2227-7080
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 by the authors.
File Version publisher
DOI 10.3390/technologies13040139
Web of Science KeyUT 001474287400001
Related Url isVersionOf https://doi.org/10.3390/technologies13040139
FullText URL fulltext.pdf
Author Tokushige, Keisuke| Asai, Shota| Abe, Takumi|
Keywords 3,3-dialkoxyisatins isatins ketalization iodine indole alkaloid
Published Date 2025-03-17
Publication Title Chemistry
Volume volume7
Issue issue2
Publisher MDPI
Start Page 43
ISSN 2624-8549
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 by the authors.
File Version publisher
DOI 10.3390/chemistry7020043
Web of Science KeyUT 001474407600001
Related Url isVersionOf https://doi.org/10.3390/chemistry7020043
FullText URL fulltext.pdf
Author Yoshida, Masashi| Ejiri, Kentaro| Matsuo, Naoaki| Naito, Takanori| Kuroda, Kazuhiro| Tokioka, Koji| Hatanaka, Kunihiko| Fujimoto, Ryohei| Yamaoka, Hidenaru| Kajikawa, Yutaka| Suruga, Kazuki| Sugiyama, Hiroki| Miyaji, Tsuyoshi| Morimoto, Yoshimasa| Okamura, Nobuhiro| Sarashina, Toshihiro| Akagi, Satoshi| Miyoshi, Toru| Nakamura, Kazufumi| Ito, Hiroshi| Yuasa, Shinsuke|
Keywords Factor Xa inhibitors Anticoagulation effects Cancer Venous thromboembolism
Published Date 2025-04-16
Publication Title Thrombosis Journal
Volume volume23
Issue issue1
Publisher BMC
Start Page 36
ISSN 1477-9560
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025.
File Version publisher
PubMed ID 40241057
DOI 10.1186/s12959-025-00720-0
Web of Science KeyUT 001469332700001
Related Url isVersionOf https://doi.org/10.1186/s12959-025-00720-0
FullText URL fulltext.pdf
Author Umeda, Hibiki| Shigeyasu, Kunitoshi| Takahashi, Toshiaki| Moriwake, Kazuya| Kondo, Yoshitaka| Yoshida, Kazuhiro| Takeda, Sho| Yano, Shuya| Matsumi, Yuki| Kishimoto, Hiroyuki| Fuji, Tomokazu| Yasui, Kazuya| Yamamoto, Hideki| Takagi, Kosei| Kayano, Masashi| Michiue, Hiroyuki| Nakamura, Keiichiro| Mori, Yoshiko| Teraishi, Fuminori| Tazawa, Hiroshi| Umeda, Yuzo| Kagawa, Shunsuke| Goel, Ajay| Fujiwara, Toshiyoshi|
Keywords RNA-editing Macrophage Chemoresistance Biomarker Colorectal cancer
Published Date 2025-04-16
Publication Title Molecular Cancer
Volume volume24
Issue issue1
Publisher BMC
Start Page 116
ISSN 1476-4598
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025.
File Version publisher
PubMed ID 40241135
DOI 10.1186/s12943-025-02312-y
Web of Science KeyUT 001470204500003
Related Url isVersionOf https://doi.org/10.1186/s12943-025-02312-y
FullText URL fulltext.pdf
Author Kamio, Tomohiro| Kono, Yoshiyasu| Hirosuna, Kensuke| Ozato, Toshiki| Yamamoto, Hideki| Hirasawa, Akira| Ennishi, Daisuke| Tomida, Shuta| Toyooka, Shinichi| Otsuka, Motoyuki|
Keywords comprehensive genomic profiling early-onset gastric cancer oxaliplatin TP53
Published Date 2025-04-18
Publication Title Cancer Medicine
Volume volume14
Issue issue8
Publisher Wiley
Start Page e70793
ISSN 2045-7634
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 40249206
DOI 10.1002/cam4.70793
Web of Science KeyUT 001469550900001
Related Url isVersionOf https://doi.org/10.1002/cam4.70793
FullText URL fulltext.pdf
Author Kuraoka, Sakiko| Kawano, Seiji| Ino, Shoko| Satomi, Takuya| Hamada, Kenta| Kono, Yoshiyasu| Iwamuro, Masaya| Kawahara, Yoshiro| Tanaka, Takehiro| Okada, Hiroyuki| Otsuka, Motoyuki|
Keywords autoimmune gastritis eradication gastric cancer Helicobacter pylori
Published Date 2025-02-01
Publication Title Internal Medicine
Volume volume64
Issue issue3
Publisher Japanese Society of Internal Medicine
Start Page 343
End Page 350
ISSN 0918-2918
NCID AA10827774
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders Ⓒ 2025 The Japanese Society of Internal Medicine
File Version publisher
PubMed ID 38960692
DOI 10.2169/internalmedicine.3617-24
Web of Science KeyUT 001470394600003
Related Url isVersionOf https://doi.org/10.2169/internalmedicine.3617-24
FullText URL fulltext.pdf
Author Sudo, Ryutaro| Miyamoto, Kohta| Ido, Hirofumi|
Keywords Laminated veneer lumber (LVL) Partial compressive load Bearing strength Embedment strength Partial compression perpendicular to grain (PCPG) Adhesive layer
Published Date 2025-04-19
Publication Title Journal of Wood Science
Volume volume71
Issue issue1
Publisher Springer
Start Page 19
ISSN 1435-0211
NCID AA11200007
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025.
File Version publisher
DOI 10.1186/s10086-025-02195-z
Web of Science KeyUT 001469993800002
Related Url isVersionOf https://doi.org/10.1186/s10086-025-02195-z
FullText URL fulltext.pdf
Author Honda, Manami| Iwamuro, Masaya| Tanaka, Takehiro| Yamasaki, Yasushi| Kawano, Seiji| Hiraoka, Sakiko| Kawahara, Yoshiro| Otsuka, Motoyuki|
Keywords colonoscopy esophagogastroduodenoscopy gastrointestinal neoplasms gastrointestinal stromal tumor neurofibromatosis
Published Date 2025-04-16
Publication Title JGH Open
Volume volume9
Issue issue4
Publisher Wiley
Start Page e70151
ISSN 2397-9070
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 40247846
DOI 10.1002/jgh3.70151
Web of Science KeyUT 001468535400001
Related Url isVersionOf https://doi.org/10.1002/jgh3.70151
FullText URL eriseki_41.pdf
Author 木村 理| 山口 雄治| 宇田津 徹朗| 田﨑 博之| 那須 浩郎| 白石 純|
Publication Title 岡山大学構内遺跡発掘調査報告
Published Date 2025-03-21
Volume volume41
language Japanese
File Version publisher
Pages 86p. 14図版
Title Alternative Bulletin of Cultural Heritage Management Division Research Institute for the Dynamics of Civilizations Okayama University 2023
FullText URL barc_2023.pdf
Author 柴田 亮| パレオ・ラボAMS年代測定グループ| 木村 理| 野﨑 貴博| 山口 雄治| 岩﨑 志保|
Publication Title Bulletin of Cultural Heritage Management Division Research Institute for the Dynamics of Civilizations Okayama University
Published Date 2025-02-20
Volume volume2023
ISSN 2758-9625
language Japanese
Copyright Holders ⒸCultural Heritage Management Division, Research Institute for the Dynamics of Civilizations, Okayama University
File Version publisher
Pages vi, 80 p.
JaLCDOI 10.18926/AMO/68654
FullText URL 79_2_139.pdf
Author Takeda, Yasushige| Noma, Kazuhiro| Maeda, Naoaki| Mizusawa, Yohei| Matsumoto, Hijiri| Kondo, Yuhei| Kunitomo, Tomoyoshi| Tanoue, Yukinori| Hashimoto, Masashi| Tanabe, Shunsuke| Fujiwara, Toshiyoshi|
Abstract In thoracic esophageal cancer, lymph node dissection around the recurrent laryngeal nerve is crucial but poses a risk of nerve palsy, affecting postoperative quality of life. In cases with an aberrant right subclavian artery (ARSA), the right recurrent laryngeal nerve is absent, and the non-recurrent inferior laryngeal nerve (NRILN) enters the larynx directly from the vagus nerve in the cervical region. Identifying the course of the NRILN is vital to avoid injury. A case of esophageal cancer with an ARSA, in which the course of the NRILN was preserved using the Nerve Integrity Monitoring (NIM) system during surgery, is described.
Keywords esophageal cancer intraoperative nerve monitoring aberrant right subclavian artery non-recurrent inferior laryngeal nerve thoracoscopic esophagectomy
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2025-04
Volume volume79
Issue issue2
Publisher Okayama University Medical School
Start Page 139
End Page 144
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/68652
FullText URL 79_2_129.pdf
Author Tsuji, Akihiro| Shiode, Yusuke| Kimura, Shuhei| Hosokawa, Mio| Matoba, Ryo| Morita, Tetsuro| Takahashi, Kosuke| Morizane, Yuki|
Abstract A 66-year-old woman presented with significant anterior capsule contraction and intraocular lens dislocation in both eyes 4 months after cataract surgery. Postoperative examinations such as fluorescein angiography, Goldmann perimetry, and electroretinography revealed retinitis pigmentosa (RP). Patients with significant anterior capsule contraction after cataract surgery should be closely examined because RP may be a contributing factor.
Keywords retinitis pigmentosa intraocular lens anterior capsule contraction
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2025-04
Volume volume79
Issue issue2
Publisher Okayama University Medical School
Start Page 129
End Page 134
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/68649
FullText URL 79_2_109.pdf
Author Awai, Kyoko| Nakatsuka, Mikiya|
Abstract The status of postpartum depression was elucidated herein with the use of the Edinburgh Postnatal Depression Scale (EPDS) in women in Shikoku, Japan who became pregnant and gave birth after undergoing infertility treatment, including assisted reproductive technology (ART). The assessment was performed during their children’s 4-month health examination. The relationships between postpartum depression and the mothers’ background factors and scores on the Big Five personality traits scale were also examined. Of the Big Five personality traits, the scores for neuroticism were significantly higher in the ART group (n=71) than in the general infertility treatment (n=118) and natural pregnancy (n=872) groups. No significant differences in EPDS scores were seen among these three groups. A logistic regression analysis showed that neuroticism was associated with an EPDS score ≧9 points, (which is suggestive of postpartum depression, ) in all groups. Moreover, although a long-standing marriage had an inhibitory effect on postpartum depression in the natural pregnancy group, no such trend was seen in the ART group, which included many women with long-standing marriages. Particularly for women who become pregnant by ART, an individualized response that pays close attention to the woman’s personality traits is needed.
Keywords infertility treatment assisted reproductive technology postpartum postpartum depression personality trait
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-04
Volume volume79
Issue issue2
Publisher Okayama University Medical School
Start Page 109
End Page 116
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/68648
FullText URL 79_2_101.pdf
Author Isozaki, Hiroshi| Matsumoto, Sasau| Takama, Takehiro| Isozaki, Yuka|
Abstract To evaluate the effectiveness of postoperative irradiation (POI) for patients with cN0 early breast cancer, we retrospectively analyzed the cases of 650 consecutive breast cancer patients who underwent sentinel lymph node (SLN)-guided surgery (2005-2022) at our hospital. In this cohort, 53% (278/521) of the patients who underwent breast conservative surgery (BCS) and 96% (124/129) of those treated with mastectomy did not receive POI. The patients who underwent BCS were treated with POI using opposing tangential field irradiation. A false negative (FN) SLN was retrospectively defined as a negative metastasis in SLN plus positive recurrence in the axillary lymph nodes. Recurrence was detected in 83 patients. A logistic regression analysis revealed that the nuclear grade (odds ratio [OR] 1.69), POI (OR 0.41), and postoperative hormone therapy (OR 0.40) were each significantly related to recurrence. The 26.1% (12/46) FN rate of the non-POI patients decreased to 5.8% (1/17) compared to those treated with POI. The rate of axillary recurrence was significantly lower in the POI group (0.4%) versus the non-POI group (2.7%) (p=0.0355). The rate of locoregional recurrence was also significantly lower in the POI group (2.0%) versus the non-POI group (13.4%) (p<0.0001). No significant difference was observed in the rate of distant recurrence between the POI (4.0%) and non-POI (3.3%) (p=0.831) groups. These results indicated that the postoperative opposing tangential field irradiation of conserved breast tissue inhibited recurrence in the axillary lymph nodes.
Keywords breast cancer postoperative irradiation radiation therapy sentinel lymph nodes recurrence
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-04
Volume volume79
Issue issue2
Publisher Okayama University Medical School
Start Page 101
End Page 107
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True