result 22966 件
Title Alternative | Questionnaire survey of junior and mid-career otolaryngologists' attitudes towards clinical research |
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Author | Uraguchi, Kensuke| Yorifuji, Takashi| Takao, Soshi| Sugaya, Akiko| Ando, Mizuo| |
Abstract | Introduction : Clinical research is crucial for the advancement of medicine, but modern otolaryngologists' attitudes regarding clinical research have not been known. This study was conducted to survey the background, knowledge, and interest in clinical research among junior and mid-career otolaryngologists. Methods : A questionnaire survey was distributed to 34 otolaryngologists with ≤15 years' clinical experience working at Okayama University and its affiliated facilities. The respondents were divided into junior (non-specialists) and mid-career otolaryngologists (specialists) based on whether they were board-certified otolaryngologists. The survey assessed their background, understanding, and interest in clinical research. Results : Twenty-nine otolaryngologists (83%) responded (10 junior and 19 mid-career otolaryngologists). There was significant individual variation in their interest and knowledge of clinical research. However, approximately half of the respondents indicated that they were not interested in and/or had never engaged in clinical research. Conclusion : The data collected by this survey contribute to our understanding of the current state of clinical research engagement among junior and mid-career otolaryngologists, and they can serve as a basis for exploring future strategies to increase this engagement. |
Keywords | 臨床研究 (clinical research) 統計解析 (statistical analysis) ビッグデータ (bigdata) 質問紙調査 (questionnaire survey) |
Publication Title | Journal of Okayama Medical Association |
Published Date | 2025-04-01 |
Volume | volume137 |
Issue | issue1 |
Start Page | 20 |
End Page | 24 |
ISSN | 0030-1558 |
Related Url | isVersionOf https://doi.org/10.4044/joma.137.20 |
language | Japanese |
Copyright Holders | Copyright (c) 2025 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.137.20 |
Title Alternative | The potential and prospects of organ generation medicine |
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Author | Mori, Munemasa| |
Keywords | organ generation regeneration bioengineering |
Publication Title | Journal of Okayama Medical Association |
Published Date | 2025-04-01 |
Volume | volume137 |
Issue | issue1 |
Start Page | 15 |
End Page | 19 |
ISSN | 0030-1558 |
Related Url | isVersionOf https://doi.org/10.4044/joma.137.15 |
language | Japanese |
Copyright Holders | Copyright (c) 2025 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.137.15 |
JaLCDOI | 10.18926/ESR/68676 |
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Title Alternative | Improved sedimentary layer model including the accretionary prism in the fore-arc region of the Ryukyu arc, Japan |
FullText URL | esr_031_001_015.pdf |
Author | KOMATSU, Masanao| URAKAMI, Sohei| OKAMOTO, Taro| TAKENAKA, Hiroshi| |
Abstract | We combine the recent seismic reflection profiles to construct a new seismic velocity model of the sedimentary layer incorporating the accretionary prism along the Ryukyu trench. In constructing the new model, we refer to the zoning (ZONE1 to ZONE4) identified by Okamura et al. (2017, Tectonophys.). The construction process consists of the following steps: First, we digitize either unconformities or VP=4 to 5 km/s lines as the seismic basement, whichever is more clearly identifiable. Second, the digitized thickness data of the sedimentary layer from the reflection profiles are geometrically modeled and interpolated to make the three-dimensional structure model. Finally, we supplement the external region of the constructed 3-D sedimentary model using the J-SHIS model provided by the NIED to complete the velocity structure model in the entire Ryukyu arc. The main features of our model are as follows: In ZONE1, off Ishigaki-jima island, the thick sedimentary layer extends about 50 km wide from the Ryukyu trench. In ZONE2, off Miyako-jima island, the thinner layer compared to the other zones is found near the trench, with a thin sedimentary terrace covering the area behind it. In ZONE3, off Okinawa-jima island, the sedimentary layer deepens as it approaches the trench. In ZONE4, off Tokara islands, the deepest layer among all zones is identified. We then conduct 3-D finite-difference simulations of seismic wave propagation using the new and the previous models to confirm the improvement of the new model. In the simulations, the effects of the accretionary prism along the Ryukyu trench on the seismic wave propagation are clearly identified. |
Keywords | Sedimentary layer model Accretionary prism Ryukyu arc |
Publication Title | Okayama University Earth Science Report |
Published Date | 2025-03-31 |
Volume | volume31 |
Issue | issue1 |
Start Page | 1 |
End Page | 15 |
ISSN | 1340-7414 |
language | Japanese |
Copyright Holders | © 2025 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
File Version | publisher |
Author | Ozato, Toshiki| Kono, Yoshiyasu| Horiguchi, Shigeru| Tsutsumi, Koichiro| Yamamoto, Hideki| Hirasawa, Akira| Ennishi, Daisuke| Tomida, Shuta| Toyooka, Shinichi| Otsuka, Motoyuki| |
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Keywords | Homologous recombination repair Small bowel adenocarcinoma Genome |
Note | © 2025 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Apr. 2026.| |
Published Date | 2025-05-02 |
Publication Title | European Journal of Cancer |
Volume | volume220 |
Publisher | Elsevier BV |
Start Page | 115401 |
ISSN | 0959-8049 |
NCID | AA1075407X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 Elsevier Ltd. |
File Version | author |
PubMed ID | 40188744 |
DOI | 10.1016/j.ejca.2025.115401 |
Web of Science KeyUT | 001465491700001 |
Related Url | isVersionOf https://doi.org/10.1016/j.ejca.2025.115401 |
FullText URL | fulltext.pdf |
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Author | Shinaoka, Akira| Kimata, Yoshihiro| |
Keywords | Lymphedema Lymphatic function Lymph flow Chylothorax Chylous ascites,lymph velocity |
Published Date | 2025-04-24 |
Publication Title | Scientific Reports |
Volume | volume15 |
Issue | issue1 |
Publisher | Nature Portfolio |
Start Page | 14323 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2025 |
File Version | publisher |
PubMed ID | 40275043 |
DOI | 10.1038/s41598-025-99416-8 |
Web of Science KeyUT | 001475676100005 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-025-99416-8 |
FullText URL | fulltext.pdf |
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Author | Ando, Yushin| Kobo, Akinao| Niwa, Tatsuya| Yamakawa, Ayako| Konoma, Suzuna| Kobayashi, Yuki| Nureki, Osamu| Taguchi, Hideki| Itoh, Yuzuru| Chadani, Yuhei| |
Published Date | 2025-03-08 |
Publication Title | Nature Communications |
Volume | volume16 |
Issue | issue1 |
Publisher | Nature Portfolio |
Start Page | 2323 |
ISSN | 2041-1723 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2025 |
File Version | publisher |
PubMed ID | 40057501 |
DOI | 10.1038/s41467-025-57659-z |
Web of Science KeyUT | 001462675700032 |
Related Url | isVersionOf https://doi.org/10.1038/s41467-025-57659-z |
FullText URL | fulltext.pdf |
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Author | Kong, Dezheng| Funabiki, Nobuo| Fang, Shihao| Noprianto, Mitsuhiro| Okayasu, Mitsuhiro| Puspitaningayu, Pradini| |
Keywords | creep test Raspberry Pi dial gauge needle reading smart lighting |
Published Date | 2025-04-02 |
Publication Title | Technologies |
Volume | volume13 |
Issue | issue4 |
Publisher | MDPI |
Start Page | 139 |
ISSN | 2227-7080 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 by the authors. |
File Version | publisher |
DOI | 10.3390/technologies13040139 |
Web of Science KeyUT | 001474287400001 |
Related Url | isVersionOf https://doi.org/10.3390/technologies13040139 |
FullText URL | fulltext.pdf |
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Author | Tokushige, Keisuke| Asai, Shota| Abe, Takumi| |
Keywords | 3,3-dialkoxyisatins isatins ketalization iodine indole alkaloid |
Published Date | 2025-03-17 |
Publication Title | Chemistry |
Volume | volume7 |
Issue | issue2 |
Publisher | MDPI |
Start Page | 43 |
ISSN | 2624-8549 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 by the authors. |
File Version | publisher |
DOI | 10.3390/chemistry7020043 |
Web of Science KeyUT | 001474407600001 |
Related Url | isVersionOf https://doi.org/10.3390/chemistry7020043 |
FullText URL | fulltext.pdf |
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Author | Yoshida, Masashi| Ejiri, Kentaro| Matsuo, Naoaki| Naito, Takanori| Kuroda, Kazuhiro| Tokioka, Koji| Hatanaka, Kunihiko| Fujimoto, Ryohei| Yamaoka, Hidenaru| Kajikawa, Yutaka| Suruga, Kazuki| Sugiyama, Hiroki| Miyaji, Tsuyoshi| Morimoto, Yoshimasa| Okamura, Nobuhiro| Sarashina, Toshihiro| Akagi, Satoshi| Miyoshi, Toru| Nakamura, Kazufumi| Ito, Hiroshi| Yuasa, Shinsuke| |
Keywords | Factor Xa inhibitors Anticoagulation effects Cancer Venous thromboembolism |
Published Date | 2025-04-16 |
Publication Title | Thrombosis Journal |
Volume | volume23 |
Issue | issue1 |
Publisher | BMC |
Start Page | 36 |
ISSN | 1477-9560 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2025. |
File Version | publisher |
PubMed ID | 40241057 |
DOI | 10.1186/s12959-025-00720-0 |
Web of Science KeyUT | 001469332700001 |
Related Url | isVersionOf https://doi.org/10.1186/s12959-025-00720-0 |
FullText URL | fulltext.pdf |
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Author | Umeda, Hibiki| Shigeyasu, Kunitoshi| Takahashi, Toshiaki| Moriwake, Kazuya| Kondo, Yoshitaka| Yoshida, Kazuhiro| Takeda, Sho| Yano, Shuya| Matsumi, Yuki| Kishimoto, Hiroyuki| Fuji, Tomokazu| Yasui, Kazuya| Yamamoto, Hideki| Takagi, Kosei| Kayano, Masashi| Michiue, Hiroyuki| Nakamura, Keiichiro| Mori, Yoshiko| Teraishi, Fuminori| Tazawa, Hiroshi| Umeda, Yuzo| Kagawa, Shunsuke| Goel, Ajay| Fujiwara, Toshiyoshi| |
Keywords | RNA-editing Macrophage Chemoresistance Biomarker Colorectal cancer |
Published Date | 2025-04-16 |
Publication Title | Molecular Cancer |
Volume | volume24 |
Issue | issue1 |
Publisher | BMC |
Start Page | 116 |
ISSN | 1476-4598 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2025. |
File Version | publisher |
PubMed ID | 40241135 |
DOI | 10.1186/s12943-025-02312-y |
Web of Science KeyUT | 001470204500003 |
Related Url | isVersionOf https://doi.org/10.1186/s12943-025-02312-y |
FullText URL | fulltext.pdf |
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Author | Kamio, Tomohiro| Kono, Yoshiyasu| Hirosuna, Kensuke| Ozato, Toshiki| Yamamoto, Hideki| Hirasawa, Akira| Ennishi, Daisuke| Tomida, Shuta| Toyooka, Shinichi| Otsuka, Motoyuki| |
Keywords | comprehensive genomic profiling early-onset gastric cancer oxaliplatin TP53 |
Published Date | 2025-04-18 |
Publication Title | Cancer Medicine |
Volume | volume14 |
Issue | issue8 |
Publisher | Wiley |
Start Page | e70793 |
ISSN | 2045-7634 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 The Author(s). |
File Version | publisher |
PubMed ID | 40249206 |
DOI | 10.1002/cam4.70793 |
Web of Science KeyUT | 001469550900001 |
Related Url | isVersionOf https://doi.org/10.1002/cam4.70793 |
FullText URL | fulltext.pdf |
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Author | Kuraoka, Sakiko| Kawano, Seiji| Ino, Shoko| Satomi, Takuya| Hamada, Kenta| Kono, Yoshiyasu| Iwamuro, Masaya| Kawahara, Yoshiro| Tanaka, Takehiro| Okada, Hiroyuki| Otsuka, Motoyuki| |
Keywords | autoimmune gastritis eradication gastric cancer Helicobacter pylori |
Published Date | 2025-02-01 |
Publication Title | Internal Medicine |
Volume | volume64 |
Issue | issue3 |
Publisher | Japanese Society of Internal Medicine |
Start Page | 343 |
End Page | 350 |
ISSN | 0918-2918 |
NCID | AA10827774 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | Ⓒ 2025 The Japanese Society of Internal Medicine |
File Version | publisher |
PubMed ID | 38960692 |
DOI | 10.2169/internalmedicine.3617-24 |
Web of Science KeyUT | 001470394600003 |
Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.3617-24 |
FullText URL | fulltext.pdf |
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Author | Sudo, Ryutaro| Miyamoto, Kohta| Ido, Hirofumi| |
Keywords | Laminated veneer lumber (LVL) Partial compressive load Bearing strength Embedment strength Partial compression perpendicular to grain (PCPG) Adhesive layer |
Published Date | 2025-04-19 |
Publication Title | Journal of Wood Science |
Volume | volume71 |
Issue | issue1 |
Publisher | Springer |
Start Page | 19 |
ISSN | 1435-0211 |
NCID | AA11200007 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2025. |
File Version | publisher |
DOI | 10.1186/s10086-025-02195-z |
Web of Science KeyUT | 001469993800002 |
Related Url | isVersionOf https://doi.org/10.1186/s10086-025-02195-z |
FullText URL | fulltext.pdf |
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Author | Honda, Manami| Iwamuro, Masaya| Tanaka, Takehiro| Yamasaki, Yasushi| Kawano, Seiji| Hiraoka, Sakiko| Kawahara, Yoshiro| Otsuka, Motoyuki| |
Keywords | colonoscopy esophagogastroduodenoscopy gastrointestinal neoplasms gastrointestinal stromal tumor neurofibromatosis |
Published Date | 2025-04-16 |
Publication Title | JGH Open |
Volume | volume9 |
Issue | issue4 |
Publisher | Wiley |
Start Page | e70151 |
ISSN | 2397-9070 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 The Author(s). |
File Version | publisher |
PubMed ID | 40247846 |
DOI | 10.1002/jgh3.70151 |
Web of Science KeyUT | 001468535400001 |
Related Url | isVersionOf https://doi.org/10.1002/jgh3.70151 |
FullText URL | eriseki_41.pdf |
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Author | 木村 理| 山口 雄治| 宇田津 徹朗| 田﨑 博之| 那須 浩郎| 白石 純| |
Publication Title | 岡山大学構内遺跡発掘調査報告 |
Published Date | 2025-03-21 |
Volume | volume41 |
language | Japanese |
File Version | publisher |
Pages | 86p. 14図版 |
Title Alternative | Bulletin of Cultural Heritage Management Division Research Institute for the Dynamics of Civilizations Okayama University 2023 |
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FullText URL | barc_2023.pdf |
Author | 柴田 亮| パレオ・ラボAMS年代測定グループ| 木村 理| 野﨑 貴博| 山口 雄治| 岩﨑 志保| |
Publication Title | Bulletin of Cultural Heritage Management Division Research Institute for the Dynamics of Civilizations Okayama University |
Published Date | 2025-02-20 |
Volume | volume2023 |
ISSN | 2758-9625 |
language | Japanese |
Copyright Holders | ⒸCultural Heritage Management Division, Research Institute for the Dynamics of Civilizations, Okayama University |
File Version | publisher |
Pages | vi, 80 p. |
JaLCDOI | 10.18926/AMO/68654 |
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FullText URL | 79_2_139.pdf |
Author | Takeda, Yasushige| Noma, Kazuhiro| Maeda, Naoaki| Mizusawa, Yohei| Matsumoto, Hijiri| Kondo, Yuhei| Kunitomo, Tomoyoshi| Tanoue, Yukinori| Hashimoto, Masashi| Tanabe, Shunsuke| Fujiwara, Toshiyoshi| |
Abstract | In thoracic esophageal cancer, lymph node dissection around the recurrent laryngeal nerve is crucial but poses a risk of nerve palsy, affecting postoperative quality of life. In cases with an aberrant right subclavian artery (ARSA), the right recurrent laryngeal nerve is absent, and the non-recurrent inferior laryngeal nerve (NRILN) enters the larynx directly from the vagus nerve in the cervical region. Identifying the course of the NRILN is vital to avoid injury. A case of esophageal cancer with an ARSA, in which the course of the NRILN was preserved using the Nerve Integrity Monitoring (NIM) system during surgery, is described. |
Keywords | esophageal cancer intraoperative nerve monitoring aberrant right subclavian artery non-recurrent inferior laryngeal nerve thoracoscopic esophagectomy |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2025-04 |
Volume | volume79 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 139 |
End Page | 144 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
JaLCDOI | 10.18926/AMO/68652 |
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FullText URL | 79_2_129.pdf |
Author | Tsuji, Akihiro| Shiode, Yusuke| Kimura, Shuhei| Hosokawa, Mio| Matoba, Ryo| Morita, Tetsuro| Takahashi, Kosuke| Morizane, Yuki| |
Abstract | A 66-year-old woman presented with significant anterior capsule contraction and intraocular lens dislocation in both eyes 4 months after cataract surgery. Postoperative examinations such as fluorescein angiography, Goldmann perimetry, and electroretinography revealed retinitis pigmentosa (RP). Patients with significant anterior capsule contraction after cataract surgery should be closely examined because RP may be a contributing factor. |
Keywords | retinitis pigmentosa intraocular lens anterior capsule contraction |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2025-04 |
Volume | volume79 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 129 |
End Page | 134 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
JaLCDOI | 10.18926/AMO/68649 |
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FullText URL | 79_2_109.pdf |
Author | Awai, Kyoko| Nakatsuka, Mikiya| |
Abstract | The status of postpartum depression was elucidated herein with the use of the Edinburgh Postnatal Depression Scale (EPDS) in women in Shikoku, Japan who became pregnant and gave birth after undergoing infertility treatment, including assisted reproductive technology (ART). The assessment was performed during their children’s 4-month health examination. The relationships between postpartum depression and the mothers’ background factors and scores on the Big Five personality traits scale were also examined. Of the Big Five personality traits, the scores for neuroticism were significantly higher in the ART group (n=71) than in the general infertility treatment (n=118) and natural pregnancy (n=872) groups. No significant differences in EPDS scores were seen among these three groups. A logistic regression analysis showed that neuroticism was associated with an EPDS score ≧9 points, (which is suggestive of postpartum depression, ) in all groups. Moreover, although a long-standing marriage had an inhibitory effect on postpartum depression in the natural pregnancy group, no such trend was seen in the ART group, which included many women with long-standing marriages. Particularly for women who become pregnant by ART, an individualized response that pays close attention to the woman’s personality traits is needed. |
Keywords | infertility treatment assisted reproductive technology postpartum postpartum depression personality trait |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2025-04 |
Volume | volume79 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 109 |
End Page | 116 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
JaLCDOI | 10.18926/AMO/68648 |
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FullText URL | 79_2_101.pdf |
Author | Isozaki, Hiroshi| Matsumoto, Sasau| Takama, Takehiro| Isozaki, Yuka| |
Abstract | To evaluate the effectiveness of postoperative irradiation (POI) for patients with cN0 early breast cancer, we retrospectively analyzed the cases of 650 consecutive breast cancer patients who underwent sentinel lymph node (SLN)-guided surgery (2005-2022) at our hospital. In this cohort, 53% (278/521) of the patients who underwent breast conservative surgery (BCS) and 96% (124/129) of those treated with mastectomy did not receive POI. The patients who underwent BCS were treated with POI using opposing tangential field irradiation. A false negative (FN) SLN was retrospectively defined as a negative metastasis in SLN plus positive recurrence in the axillary lymph nodes. Recurrence was detected in 83 patients. A logistic regression analysis revealed that the nuclear grade (odds ratio [OR] 1.69), POI (OR 0.41), and postoperative hormone therapy (OR 0.40) were each significantly related to recurrence. The 26.1% (12/46) FN rate of the non-POI patients decreased to 5.8% (1/17) compared to those treated with POI. The rate of axillary recurrence was significantly lower in the POI group (0.4%) versus the non-POI group (2.7%) (p=0.0355). The rate of locoregional recurrence was also significantly lower in the POI group (2.0%) versus the non-POI group (13.4%) (p<0.0001). No significant difference was observed in the rate of distant recurrence between the POI (4.0%) and non-POI (3.3%) (p=0.831) groups. These results indicated that the postoperative opposing tangential field irradiation of conserved breast tissue inhibited recurrence in the axillary lymph nodes. |
Keywords | breast cancer postoperative irradiation radiation therapy sentinel lymph nodes recurrence |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2025-04 |
Volume | volume79 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 101 |
End Page | 107 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
File Version | publisher |
Refereed | True |