result 3115 件
| Author | Gotoh, Kazuma| Ishikawa, Toru| Shimadzu, Saori| Yabuuchi, Naoaki| Komaba, Shinichi| Takeda, Kazuyuki| Goto, Atsushi| Deguchi, Kenzo| Ohki, Shinobu| Hashi, Kenjiro| Shimizu, Tadashi| Ishida, Hiroyuki| |
|---|---|
| Published Date | 2013-03 |
| Publication Title | Journal of Power Sources |
| Volume | volume225 |
| Content Type | Journal Article |
| Author | Gotoh, Kazuma| Kinumoto, Taro| Fujii, Eiji| Yamamoto, Aki| Hashimoto, Hideki| Ohkubo, Takahiro| Itadani, Atsushi| Kuroda, Yasushige| Ishida, Hiroyuki| |
|---|---|
| Published Date | 2011-04 |
| Publication Title | Carbon |
| Volume | volume49 |
| Issue | issue4 |
| Content Type | Journal Article |
| Author | Gotoh, Kazuma| Takeda, Kazuyuki| Lerner, Michael M.| Sueishi, Yoshimi| Maruyama, Shinpei| Goto, Atsushi| Tansho, Masataka| Ohki, Shinobu| Hashi, Kenjiro| Shimizu, Tadashi| Ishida, Hiroyuki| |
|---|---|
| Published Date | 2011-10 |
| Publication Title | Carbon |
| Volume | volume49 |
| Issue | issue12 |
| Content Type | Journal Article |
| Author | Kanehara, Masayuki| Takeya, Jun| Uemura, Takafumi| Murata, Hideyuki| Takimiya, Kazuo| Sekine, Hikaru| Teranishi, Toshiharu| |
|---|---|
| Published Date | 2012-09 |
| Publication Title | Bulletin of the Chemical Society of Japan |
| Volume | volume85 |
| Issue | issue9 |
| Content Type | Journal Article |
| Author | Uma, Thanganathan| Nogami, Masayuki| |
|---|---|
| Published Date | 2009-04-01 |
| Publication Title | Journal of the Ceramic Society of Japan |
| Volume | volume117 |
| Issue | issue1364 |
| Content Type | Journal Article |
| Author | Watanabe, Koyo| Matsuura, Koji| Kawata, Fukukazu| Nagata, Kotaro| Ning, Jun| Kano, Hiroshi| |
|---|---|
| Published Date | 2012-02-01 |
| Publication Title | Biomedical Optics Express |
| Volume | volume3 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Matsuura, Koji| Takenami, Mami| Kuroda, Yuka| Hyakutake, Toru| Yanase, Shinichiro| Naruse, Keiji| |
|---|---|
| Published Date | 2012-01 |
| Publication Title | Reproductive BioMedicine Online |
| Volume | volume24 |
| Issue | issue1 |
| Content Type | Journal Article |
| Author | Sano, Hikaru| Matsuura, Koji| Naruse, Keiji| Funahashi, Hiroaki| |
|---|---|
| Published Date | 2010-09-15 |
| Publication Title | Theriogenology |
| Volume | volume74 |
| Issue | issue5 |
| Content Type | Journal Article |
| Author | Koike, Takayuki| Matsuura, Koji| Naruse, Keiji| Funahashi, Hiroaki| |
|---|---|
| Published Date | 2010-10 |
| Publication Title | Journal of Reproduction and Development |
| Volume | volume56 |
| Issue | issue5 |
| Content Type | Journal Article |
| Author | Hyakutake, Toru| Hashimoto, Yuki| Yanase, Shinichiro| Matsuura, Koji| Naruse, Keiji| |
|---|---|
| Published Date | 2009-02 |
| Publication Title | Biomedical Microdevices |
| Volume | volume11 |
| Issue | issue1 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/48965 |
|---|---|
| FullText URL | 66_5_409.pdf |
| Author | Sarai, Takaaki| Inoue, Takayuki| Fujiwara, Kazuo| Kuramoto, Koichi| |
| Abstract | The human femur is subjected to an impulsive load at its distal end during daily life. Femoral bone fracture caused by impact loading is common in elderly women. It is important to clarify the dynamic response of the femur and to evaluate the change in its stress state during impact loading. A 3-dimensional model of the femur was prepared in the present study, and the impulsive stress waves propagating from the distal end of the femur were analyzed by the dynamic finite element method. This model showed that the von Mises equivalent stress is large on the anterior and posterior sides of the mid-diaphysis when the impact direction is different from that of the bone axis. As for the femoral neck, the absolute value of minimum principal stress initially increases on the medial side;slightly later the maximum principal stress increases on the lateral side. In this case, the absolute value of the maximum principal stress was found to be larger than that of the minimum principal stress, and the absolute value of the principal stress decreased as the impact angle increased. Further, the femoral neck and the trochanter were shown to have a higher risk of bone fracture when the impact direction is coincident with the bone axis. |
| Keywords | biomechanics femur impulsive stress wave impact angle dynamic finite element analysis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2012-10 |
| Volume | volume66 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 409 |
| End Page | 415 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2012 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23093059 |
| Web of Science KeyUT | 000310253900005 |
| JaLCDOI | 10.18926/AMO/48964 |
|---|---|
| FullText URL | 66_5_399.pdf |
| Author | Jing, Shao-Wu| Wang, Ya-Di| Kuroda, Masahiro| Su, Jing-Wei| Sun, Guo-Gui| Liu, Qing| Cheng, Yun-Jie| Yang, Cong-Rong| |
| Abstract | Hypoxia-inducible factor-1α (HIF-1α) has been found to enhance tumor invasion and metastasis, but no study has reported its action in esophageal carcinoma. The goal of this study was to explore the probable mechanism of HIF-1α in the invasion and metastasis of esophageal carcinoma Eca109 cells in vitro and in vivo. mRNA and protein expression of HIF-1α, E-cadherin and matrix metalloproteinase-2 (MMP-2) under hypoxia were detected by RT-PCR and Western blotting. The effects of silencing HIF-1α on E-cadherin, MMP-2 mRNA and protein expression under hypoxia or normoxia were detected by RT-PCR and Western blotting, respectively. The invasive ability of Eca109 cells was tested using a transwell chambers. We established an Eca109-implanted tumor model and observed tumor growth and lymph node metastasis. The expression of HIF-1α, E-cadherin and MMP-2 in xenograft tumors was detected by Western blotting. After exposure to hypoxia, HIF-1α protein was up-regulated, both mRNA and protein levels of E-cadherin were down-regulated and MMP-2 was up-regulated, while HIF-1α mRNA showed no significant change. SiRNA could block HIF-1α effectively, increase E-cadherin expression and inhibit MMP-2 expression. The number of invading cells decreased after HIF-1α was silenced. Meanwhile, the tumor volume was much smaller, and the metastatic rate of lymph nodes and the positive rate were lower in vivo. Our observations suggest that HIF-1α inhibition might be an effective strategy to weaken invasion and metastasis in the esophageal carcinoma Eca109 cell line. |
| Keywords | hypoxia-inducible factor-1α esophageal carcinoma invasion and metastasis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2012-10 |
| Volume | volume66 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 399 |
| End Page | 407 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2012 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23093058 |
| Web of Science KeyUT | 000310253900004 |
| JaLCDOI | 10.18926/AMO/48963 |
|---|---|
| FullText URL | 66_5_387.pdf |
| Author | Chikasue, Kumiko| Kimura, Miyuki| Ikeda, Kazuyuki| Ohnishi, Takuma| Kawanishi, Satoshi| Iio, Tomoe| Kataoka, Mikio| Arao, Yujiro| |
| Abstract | To determine whether exhaled breath contains Torque teno virus (TTV) or not, we tested exhaled breath condensate (EBC) samples by semi-nested PCR assay. We detected TTV DNA in 35% (7/20) of EBC samples collected from the mouth of one of the authors, demonstrating that TTV DNA is excreted in exhaled breath with moderate frequency. TTV DNA was detected also in oral EBC samples from 4 of 6 other authors, indicating that TTV DNA excretion in exhaled breath is not an exception but rather a common phenomenon. Furthermore, the same assay could amplify TTV DNA from room air condensate (RAC) samples collected at distances of 20 and 40cm from a human face with 40 (8/20) and 35% (7/20) positive rates, respectively. TTV transmission has been reported to occur during infancy. These distances seem equivalent to that between an infant and its household members while caring for the infant. Taken together, it seems that exhaled breath is one of the possible transmission routes of TTV. We also detected TTV DNA in 25% (10/40) of RAC samples collected at a distance of more than 180cm from any human face, suggesting the risk of airborne infection with TTV in a room. |
| Keywords | Torque teno virus exhaled breath airborne infection polymerase chain reaction |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2012-10 |
| Volume | volume66 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 387 |
| End Page | 397 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2012 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23093057 |
| Web of Science KeyUT | 000310253900003 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/49508 |
| Author | Nishioka, Yasutaka| Suzumori, Koichi| Kanda, Takefumi| Wakimoto, Shuichi| |
|---|---|
| Published Date | 2010-12 |
| Publication Title | Sensors and Actuators A: Physical |
| Volume | volume164 |
| Issue | issue1-2 |
| Content Type | Journal Article |
| Author | Nagase, Jun-ya| Wakimoto, Shuichi| Satoh, Toshiyuki| Saga, Norihiko| Suzumori, Koichi| |
|---|---|
| Published Date | 2011-10 |
| Publication Title | Smart Materials and Structures |
| Volume | volume20 |
| Issue | issue10 |
| Content Type | Journal Article |
| Author | Wakimoto, Shuichi| Suzumori, Koichi| Ogura, Keiko| |
|---|---|
| Published Date | 2011 |
| Publication Title | Advanced Robotics |
| Volume | volume25 |
| Issue | issue9-10 |
| Content Type | Journal Article |
| Author | Faudzi, Ahmad 'Athif Mohd| Suzumori, Koichi| Wakimoto, Shuichi| |
|---|---|
| Published Date | 2010 |
| Publication Title | Advanced Robotics |
| Volume | volume24 |
| Issue | issue10 |
| Content Type | Journal Article |
| Author | Konishi, Masami| Nakano, Koichi| Imai, Jun| |
|---|---|
| Published Date | 2011-06-01 |
| Publication Title | 鉄と鋼 |
| Volume | volume97 |
| Issue | issue6 |
| Content Type | Journal Article |
| Author | Itoh, Ryota| Nagataki, Hiroyuki| Ooshita, Fukuhito| Kakugawa, Hirotsugu| Masuzawa, Toshimitsu| |
|---|---|
| Published Date | 2007-07-10 |
| Publication Title | 8th International Conference on Information Technology Based Higher Education and Training |
| Content Type | Conference Paper |
| Author | Okazaki, Hiroyuki| Yoshida, Rikiya| Muro, Takayuki| Nakamura, Tetsuya| Wakita, Takanori| Muraoka, Yuji| Hirai, Masaaki| Kato, Hiromitsu| Yamasaki, Satoshi| Takano, Yoshihiko| Ishii, Satoshi| Oguchi, Tamio| Yokoya, Takayoshi| |
|---|---|
| Published Date | 2011-02-21 |
| Publication Title | Applied Physics Letters |
| Volume | volume98 |
| Issue | issue8 |
| Content Type | Journal Article |
