脳の窒素代謝 第8編 実験的衝撃の大黒鼠脳髄アミノ酸に及ぼす影響について

In the determinations of glutamic acid, glutamine, γ-aminobutylic acid, and aspartic acid in the rat brain by paper chromatography, the author obtained the following results: 1) In the normal rat brain, the value determined for glutamic acid was 158.4 mg.%: for glutamine 95.5 mg.%; for γ-aminobutylic acid 35.2 mg.% ; and for aspartic acid 30.8 mg.%, respectively. 2) After the convulsion caused by electro-shock, the contents of glutamic acid and γ-amino-butylic acid in the brain showed a decrease. 3) In the animals treated with electro-shocks for 13 to 18 days (2 times/day), the content of γ-amino-butylic acid in the brain decreased, while that of glutamine an increase, and aspartic acid increased markedly. 4) During the coma caused by insulin shocks, the content of glutamic acid showed a decrease, while that of glutamine an increase, and aspartic acid increased markedly. 5) In the group given repeated insulin shocks, glutamic acid drecreased while glutamine increased; and aspartic acid increased markedly.