result 3251 件
| Author | Takayama, Hiroki| Miyake, Yasuhiro| Nouso, Kazuhiro| Ikeda, Fusao| Shiraha, Hidenori| Takaki, Akinobu| Kobashi, Haruhiko| Yamamoto, Kazuhide| |
|---|---|
| Published Date | 2011-01 |
| Publication Title | Journal of Gastroenterology and Hepatology |
| Volume | volume26 |
| Issue | issue1 |
| Content Type | Journal Article |
| Author | Higashi, Reiji| Uraoka, Toshio| Kato, Jun| Kuwaki, Kenji| Ishikawa, Shin| Saito, Yutaka| Matsuda, Takahisa| Ikematsu, Hiroaki| Sano, Yasushi| Suzuki, Seiyuu| Murakami, Yoshitaka| Yamamoto, Kazuhide| |
|---|---|
| Published Date | 2010-07 |
| Publication Title | Gastrointestinal Endoscopy |
| Volume | volume72 |
| Issue | issue1 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/okadai-bun-kiyou/52721 |
|---|---|
| FullText URL | jfl_061_019_022.pdf |
| Author | Tanaka, Tomoko| Hyodo, Yoshimi| |
| Publication Title | 岡山大学文学部紀要 |
| Published Date | 2014-07-25 |
| Volume | volume61 |
| Start Page | 19 |
| End Page | 22 |
| ISSN | 0285-4864 |
| language | English |
| File Version | publisher |
| NAID | 120005457111 |
| Title Alternative | Sublingual Immunotherapy |
|---|---|
| FullText URL | 126_165.pdf |
| Author | Okano, Mitsuhiro| |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-08-01 |
| Volume | volume126 |
| Issue | issue2 |
| Start Page | 165 |
| End Page | 166 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.165 |
| NAID | 130004685270 |
| Title Alternative | Drug interaction (30. combination with therapeutic drugs for chronic pain) |
|---|---|
| FullText URL | 126_159.pdf |
| Author | Ogawa, Atsushi| Kitamura, Yoshihisa| Sendo, Toshiaki| |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-08-01 |
| Volume | volume126 |
| Issue | issue2 |
| Start Page | 159 |
| End Page | 163 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.159 |
| NAID | 130004685269 |
| Title Alternative | Guidelines for the treatment of dementia |
|---|---|
| FullText URL | 126_155.pdf |
| Author | Kurata, Tomoko| Abe, Koji| |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-08-01 |
| Volume | volume126 |
| Issue | issue2 |
| Start Page | 155 |
| End Page | 157 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.155 |
| NAID | 130004685268 |
| Title Alternative | Molecular targeted therapy in myeloma and lymphoma |
|---|---|
| FullText URL | 126_143.pdf |
| Author | Saeki, Kyosuke| Maeda, Yoshinobu| Tanimoto, Mitsune| |
| Keywords | 骨髄腫 リンパ腫 分子標的治療薬 |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-08-01 |
| Volume | volume126 |
| Issue | issue2 |
| Start Page | 143 |
| End Page | 150 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.143 |
| NAID | 130004685266 |
| Title Alternative | Induction therapy followed by surgery for non small-cell lung cancer |
|---|---|
| FullText URL | 126_103.pdf |
| Author | Toyooka, Shinichi| |
| Keywords | 非小細胞肺癌 導入療法 放射線化学療法 外科切除 |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-08-01 |
| Volume | volume126 |
| Issue | issue2 |
| Start Page | 103 |
| End Page | 107 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.103 |
| NAID | 130004685260 |
| Author | HUTTULA, Timo| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | MANO, Akiko| MALVE, Olli| KOPONEN, Sampsa| KALLIO, Kari| TASKINEN, Antti| ROPPONEN, Janne| JUNTUNEN, Janne| LIUKKO, Ninni| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | MANO, Akiko| SHUKU, Takayuki| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | ROPPONEN, Janne| HUTTULA, Timo| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | SUITO, Hiroshi| KOBAYASHI, Mika| LIUKKO, Ninni| HUTTULA, Timo| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | HUTTULA, Timo| LIUKKO, Ninni| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| JaLCDOI | 10.18926/AMO/52657 |
|---|---|
| FullText URL | 68_3_163.pdf |
| Author | Tate, Genshu| Kishimoto, Koji| Mitsuya, Toshiyuki| |
| Abstract | The aim of the present study is to address whether the molecular pathogenesis is identical among multiple basal cell carcinomas (BCCs) present in the same nevoid basal cell carcinoma syndrome (NBCCS) patient. Patient 1 is a 61-year-old (yo) Japanese female whose clinical characteristics and findings of a genetic analysis of PTCH1 have been previously described. Patient 2 is patient 1ʼs 64-yo sister who also suffered from NBCCS with a single base deletion at nucleotide 2613 in exon 16 (c.2613delC) in one PTCH1 allele. Thirteen and 3 independent specimens of BCC were applied for a molecular analysis of loss of heterozygosity (LOH) in PTCH1 in patients 1 and 2, respectively. Of particular note is that all BCC specimens examined showed a loss of the wild-type allele of exon 16 in PTCH1, thus indicating that LOH results in the biallelic disruption of PTCH1 in multiple BCCs that develop in an age- and location-independent manner in the same patient. These results indicate that the germline single base deletion of PTCH1 (c.2613 delC) is a first hit and the LOH of the wild-type allele is a second hit, implying that all 16 BCCs detected in these NBCCS sisters fit the standard two-hit model. |
| Keywords | biallelic disruption hedgehog nevoid basal cell carcinoma syndrome Patched 1 two-hit model |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-06 |
| Volume | volume68 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 163 |
| End Page | 170 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 24942795 |
| Web of Science KeyUT | 000337655600006 |
| JaLCDOI | 10.18926/AMO/52652 |
|---|---|
| FullText URL | 68_3_129.pdf |
| Author | Minoura, Akira| Wang, Da-Hong| Sato, Yoshie| Zou, Yu| Sakano, Noriko| Kubo, Masayuki| Takemoto, Kei| Masatomi, Chie| Ogino, Keiki| |
| Abstract | We examined the relationships between dietary carbohydrate, protein, fat, and the ratio of n6/n3 fatty acid intakes with the predicted 10-year coronary heart disease (CHD) risk in a general Japanese population. We used the Framingham risk score to determine the 10-year CHD risk of the subjects, who were employees of 6 companies in a single prefecture in Japan. After excluding the subjects who reported any history of angina pectoris, myocardial infarction, diabetes, or cancer, and those with missing data resulting in the inability of estimation of 10-year CHD risk and food intakes, the final data analysis was carried out for 809 subjects. The logistic regression models revealed a significantly increased odds ratio of 10-year CHD risk in the subjects with the highest tertile of carbohydrate intake (% energy) (odds ratio 3.64, 95% CI, 2.07-6.40);after adjustment for other variables, the odds ratio for the 10-year CHD risk was also higher in the subjects with the highest tertile of carbohydrate intake (odds ratio 1.72, 95% CI, 0.70-4.25). We also found that fat intake and the ratio of n6/n3 fatty acids were inversely associated with the predicted 10-year CHD risk (p for trend＜0.01). The present findings added evidence of a positive association of dietary carbohydrate and inverse associations of total fat and n6/n3 fatty acid ratio with the predicted 10-year CHD risk in a general Japanese population. |
| Keywords | fat intake carbohydrate intake ratio of n6/n3 fatty acids 10-year coronary heart disease risk Japanese |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-06 |
| Volume | volume68 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 129 |
| End Page | 135 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 24942790 |
| Web of Science KeyUT | 000337655600001 |
| Author | Nishiyama, Yuichi| |
|---|---|
| Published Date | 2014-03-25 |
| Content Type | Thesis or Dissertation |
| FullText URL | K0004995_abstract_review.pdf K0004995_fulltext.pdf |
|---|---|
| Author | 包 紅梅| |
| Published Date | 2014-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第4995号 |
| Granted Date | 2014-03-25 |
| Thesis Type | Doctor of Philosophy |
| Grantor | 岡山大学 |
| language | Japanese English |
| Author | Tarek Mohamad Mohamad Abd El Kader| |
|---|---|
| Published Date | 2014-03-25 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Kasuyama, Kenta| |
|---|---|
| Published Date | 2014-03-25 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
