result 2926 件
| Author | 渡辺 武男| |
|---|---|
| Published Date | 1957-09 |
| Publication Title | 岡山大学温泉研究所報告 |
| Volume | volume19 |
| Content Type | Conference Paper |
| Author | Yamaguchi, Kenji| |
|---|---|
| Published Date | 1957-09 |
| Publication Title | 岡山大学温泉研究所報告 |
| Volume | volume19 |
| Content Type | Conference Paper |
| Author | 末野 悌六| |
|---|---|
| Published Date | 1957-09 |
| Publication Title | 岡山大学温泉研究所報告 |
| Volume | volume19 |
| Content Type | Others |
| Author | 冨田 達| 唐木田 芳文| 桃井 斉| |
|---|---|
| Published Date | 1957-09 |
| Publication Title | 岡山大学温泉研究所報告 |
| Volume | volume19 |
| Content Type | Conference Paper |
| Author | 冨田 達| 桃井 斉| 唐木田 芳文| |
|---|---|
| Published Date | 1957-09 |
| Publication Title | 岡山大学温泉研究所報告 |
| Volume | volume19 |
| Content Type | Conference Paper |
| Author | 初田 甚一郎| 尹 一| |
|---|---|
| Published Date | 1957-09 |
| Publication Title | 岡山大学温泉研究所報告 |
| Volume | volume19 |
| Content Type | Conference Paper |
| Author | 岡山大学温泉研究所| |
|---|---|
| Published Date | 1957-09 |
| Publication Title | 岡山大学温泉研究所報告 |
| Volume | volume19 |
| Content Type | Others |
| Author | 吉田 博直| 小島 丈児| |
|---|---|
| Published Date | 1957-09 |
| Publication Title | 岡山大学温泉研究所報告 |
| Volume | volume19 |
| Content Type | Conference Paper |
| Author | 相馬 徳蔵| |
|---|---|
| Published Date | 1957-09 |
| Publication Title | 岡山大学温泉研究所報告 |
| Volume | volume19 |
| Content Type | Conference Paper |
| Author | 沼野 忠之| |
|---|---|
| Published Date | 1957-09 |
| Publication Title | 岡山大学温泉研究所報告 |
| Volume | volume19 |
| Content Type | Conference Paper |
| Author | 岡山大学温泉研究所| |
|---|---|
| Published Date | 1957-09 |
| Publication Title | 岡山大学温泉研究所報告 |
| Volume | volume19 |
| Content Type | Others |
| JaLCDOI | 10.18926/40273 |
|---|---|
| Title Alternative | On the Underground Temperatures and Radioactivities at One Meter Depth in the Misasa Hot Spring Area |
| FullText URL | pitsr_020_055_061.pdf |
| Author | Soma, Tokuzo| |
| Abstract | Methods and Results of Measurements:-- A stick of steel was driven into the ground down to one meter depth, and a narrow pipe of aluminum or brass, closed at the upper end, was inserted and the hole covered by a board and earth. (See Fig.3.) In Fig.2 the locations for the experiments are shown by x. Fig.1 gives the atmospheric temperatures at noon, October4-21,1955, when the experiments were carried out. About three hours after the above setting had been done, the gas in the hole was replaced by a bottle of water, and was collected, by driving sprayer for five minutes with apparatus as shown in Fig.5, in a can in which an autoradiographic plate was set. (See Fig.6.) The temperature in the hole was read by means of a maximum thermometer hung in the hole for ten minutes at one meter depth. Fig.7 shows the distribution of temperatures at one meter depth thus observed. Exactly twenty four hours after the above setting, the autoradiographic plate in the can (a quarter sized Fuji ET-2E plate, 15μ thick, for contact method) was developed. For developing, the plate was immersed in Ilford D-19 for fifteen minutes, then fixed with Fuji-fix for fifteen minutes, washed with running water for forty minutes, and dried. Then those autoradiographic plate was examined under the microscope of magnification ×280, to count the number of tracks of a-particles. The results obtained are shown in Fig.8. Underground Temperature Distribution:-- On the basis of the distribution of temperatures at one meter depth (Fig.7) and of other available boring data, the distribution of undergound temperatures is estimated as shown in Fig.9 (vertical section along the Misasa river). |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1958-01 |
| Volume | volume20 |
| Start Page | 55 |
| End Page | 61 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002462896 |
| JaLCDOI | 10.18926/40248 |
|---|---|
| Title Alternative | Clinical Studies on Anemia in Rheumatoid Arthritis |
| FullText URL | pitsr_025_053_069.pdf |
| Author | Yamamoto, Yasuhisa| |
| Abstract | Anemia of moderate severity is commonly present in patients suffering from rheumatoid arthritis, but one to which little attention has been paid and despite its frequency the exact mechanism of its production is uncertain. Anemia in rheumatoid arthritis is refractory to anti-anemic therapy. The presence of anemia may hinder adequate physical or orthopedic treatment and may produce a degree of lassitude that considerably aggravates the joint disability. This anemia, therefore, seemed worthy of study and investigations of three aspects are reported here: 1. Changes in peripheral blood, bone marrow, liver function and gastric acidity. 2. Alternations in iron metabolism. 3. Balneotherapy and anemia in rheumatoid arthritis. I. Peripheral Blood Picture, Liver Function, Serum Protein Fraction and Gastric Acidity. 1. The peripheral blood and bone marrow. The number of erythrocytes is 558～216×10(4)/c. mm. (average:402×10(4)/c. mm.), hemoglobin-content:110～40% (average: 78.6%), and the color index is about 1.0. The anemia of rheumatoid arthritis treated is mostly normochromic. The white blood cell count is between 11200 and 3720/c. mm. (average: 7504/c. mm.), and the number of leucocytes in 80% of the cases ranges within the normal limits. Eosinophilia is observed 27% of the cases. Films of the sternal marrow showed no major abnormality in the eight cases examined. Several minor points, however, deserve mention. The nucleated cell count was diminished in seven cases examined, and the decrease of normoblasts in bone marrow would explain the reduced red cell count in peripheral blood. The myeloid series showed a relative increase. 2. Liver function tests and gastric acidity. To illustrate the possible appearance of liver function disturbances in connection with rheumatoid arthritis, the author has made different liver function tests on patients suffering from this disease. From the results it appears that in protein metabolism tests more than 83% of the cases gave abnormal albumin/globulin ratios and Takata's and erthrocyte sedimentation reactions. The detoxication capacity determined by hippuric acid synthesis tests had decreased in 25% of the cases examined. The dye excreting capacity, determined by the bromsulfalein tolerance test, was found to be reduced in 64% of the cases examined. The urin-urobilinogen test showed positive in 28% of the cases. In all cases the insulin sensitivity test gave pathological readings. Of 40 cases examined, anacidity of gastric juice was observed in 17 cases, subacidity in other 10 cases and normacidity, hyperacidity in remammg 13 cases. Thus, a decrease in the gastric acidity was found to occur in 67.5% of the cases. 3. Serum protein fraction. The total serum protein of 31 cases with rheumatoid arthritis appeared to be on the same level as in normal material. Serum protein fraction was determined in 19 cases by paperelectrophoresis. In rheumatoid patients, albumin fraction of serum protein decreased and γ-globulin fraction increased in all cases examined, compared with the data of normal subject as a control. Alubumin/globulin ratio of rheumatoid arthritis was below the 5% rejection limit of normal value. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1959-05 |
| Volume | volume25 |
| Start Page | 53 |
| End Page | 69 |
| ISSN | 0369-7142 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/40244 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002462889 |
| JaLCDOI | 10.18926/40241 |
|---|---|
| Title Alternative | Clinical Studies on Anemia in Rheumatoid Arthritis (II) |
| FullText URL | 026_031_049.pdf |
| Author | Yamamoto, Yasuhisa| |
| Abstract | II. Iron Metabolism 1. The serum iron: The serum iron was estimated by the method of Umemoto and Yamamoto (by means of o-nitroso resorcinmonomethylether) The average serum iron level of 33 cases with rheumatoid arthritis was 47γ/100 ml., and in 27 of 33 cases (82%) the serum iron levels were shown to be below the lower limit of the normal range (5% rejection limit: 54-141γ/100 ml. ), but the concentrations of serum iron of neuralgias (degenerative Spondylosis, sciatica and painful shoulder) were mostly within the normal range. 2. Iron absorption: To investigate the possible role of poor absorption in preventing a response to oral iron therapy, the changes in serum iron were followed after a test of iron by mouth in 16 caseS with rheumatoid arthritis. The test dose was 1 gm. of reduced iron given with 30 mI. of lemonade-pepsin solution to preserve the iron in the ferrous state and obviate the effects of possible achlorhydria in rheumatoid patients. The results may be grouped under three headings: a) Large rise in serum iron: good adsorption. Three caseS (19%) showed a very large rise in serum iron after the test dose, which is similar to simple iron-deficiency anemia. b) Slight rise in serum iron: presumed poor absorption. Six cases (38%) showed a very small or negligible rise after the test dose, so that at its peak the serum iron was below the normal range. c) In the remaining 7 cases, a maximal rise in serum iron after the test dose was within the normal range. 3. The iron-binding capacity of the serum: The iron-binding capacity of the serum was estimated by means of intravenous injection of Gluferricon (Fe content: 10 mg.). The mean total iron-binding capacity of the serum in the present 13 cases with rheumatoid arthritis was 273γ/100ml., virtually the same as the normal figure (287γ /100 ml.). The degree of saturation of the iron-binding protein with iron was found to lie between 18 and 45% (average: 34%) in control sUbjects and between 7 and 24% (average: 16%) in rheumatoid patients. 4. The serum copper: The serum copper was estimated by means of diethyldithiocarbamate in rheumatoid arthritis with the following results. Healthy subjects: men (15 cases): mean 89.9±14.8γ /l00 ml., women (15 cases): mean 99.9± 12.6γ/100 ml. There is no significant difference between the two. In 10 of 17 cases (57%) with rheumatoid arthritis, the serum copper levels were shown to be above the upper limit of the normal range (57-138γ/100 ml. ・・・5% rejection limit), neuralgias were mostly (92%) within the normal range. The results of investigations upon alternations in iron metabolism of rheumatoid anemia are reported. 1. The serum iron concentration was usually reduced. 2. The intestinal absorption of iron after a single dose of 1 gm. of reduced iron was variable. Strong presumptive evidence of impaired absorption waS recognised in many cases, but some cases gave the excellent absorption. From these results, it seems that simple iron deficiency exist in some anemic caseS of rheumatoid arthritis. 3. The total iron-binding capacity of the serum was slightly reduced. 4. The degree of Saturation of iron-binding protein with iron was below nornal. 5. The serum copper concentration waS usually elevated. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1959-10 |
| Volume | volume26 |
| Start Page | 31 |
| End Page | 49 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| JaLCDOI | 10.18926/40239 |
|---|---|
| Title Alternative | Clinical Study on the Treatment of Rheumatoid Arthritis Part II. Experiences of Intraarticular Injection of Prednisolone for Rheumatoid Arthritis |
| FullText URL | 026_008_019.pdf |
| Author | Izumi, Tomokuni| |
| Abstract | Meticorterone (Prednisolone acetate) were injected into joints of 33 cases of rheumatoid arthritis, 172 times in total, with better results. Although intraarticular injection of prednisolone is, at present, to be one of the most effective treatment for rheumatoid arthritis, one must pay attention at the appearance of general effect in frequent and abundant injection. Comparative studies were performed on the effects of intraarticular injectons of prednisolone T. B. A, (on twelve cases), hydrocortisone acetate and meticorterone. Prednisolone T. B. A. was proved markedly longer effect in local with minimum general effect, It was, therefore, thought that prednisolone T. B. A. was safest and most effective in intraarticular therapy on the rheumatoid arthritis. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1959-10 |
| Volume | volume26 |
| Start Page | 8 |
| End Page | 19 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| JaLCDOI | 10.18926/40220 |
|---|---|
| Title Alternative | Study on the Separation of Uranium by Ion Exchage |
| FullText URL | pitsr_029_007_019.pdf |
| Author | Umemoto, Shunji| Sakanoue, Masanobu| |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1961-06-25 |
| Volume | volume29 |
| Start Page | 7 |
| End Page | 19 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002462881 |
| JaLCDOI | 10.18926/40205 |
|---|---|
| Title Alternative | Balneological Studies of Kaike Hot Springs (I) Effect of the Internal Use of Kaike Spring Water on Gastric Acidity |
| FullText URL | pitsr_030_014_019.pdf |
| Author | Kawata, Yoshiro| |
| Abstract | Kaike Hot Spring is situated at the seaside, in the western part of Tottori Prefecture, Japan. In chemical composition it contains 9.3 g. of salts per kilogram of spring water and may be classified as a common salt spring. The author examined the effect of the drinking of Kaike spring water on gastric acidity in 21 patients. a) Two hundred m!. of this spring water were given to 10 patients by stomach tube at 37℃. The gastric acidity of the patients was measured at 30-minute intervals for a period of 105 minutes following the administration of the spring water. In 3 cases of normal acidity and 6 cases of hyperacidiy, the spring water appeared to inhibit the secretion of gastric acid, compared with the effect of the caffein control water. b) Two hundred m!. of the spring water diluted two-fold with tap water were given to 11 patients. In two cases of normal acidity and two cases of hypoacidity, on significant difference was observed between the effects of the spring water and those of the control water. In all 7 cases of hyperacidity, however, the spring water observably depressed the acid secretion of the stomach, as compared with the effect of the control water. On the basis of these results, the author concludes that it is advisable to use the spring water diluted two-fold with tap water for the purpose of treating gastric disorders. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1962-04-25 |
| Volume | volume30 |
| Start Page | 14 |
| End Page | 19 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002401087 |
| JaLCDOI | 10.18926/40186 |
|---|---|
| Title Alternative | Our experience in combined balneo- and chrysotherapy for rheumatoid arthritis |
| FullText URL | pitsr_037_009_019.pdf |
| Author | Ezawa, Hidemitsu| |
| Abstract | There was a time when the adrenocortical hormones therapy was only available treatment for rheumatoid arthritis, but since it does not give lasting effect on chronic rheumatoid arthritis, opinions are varied as to its efficacy, so that at present we are still conducting studies about this problem. Ever since the reports on the gold therapy for rheumatoid arthritis of LANDE (1927) and FORESTIER (1929) the literature is replete with the results of gold therapy both in Europe and America. In Japan, however, it was with reports by OSHIMA (1957) and HASHIMOTO(1961) that first aroused the interest of general investigators in this gold therapy. Nevertheless, since we find no convincing methods of treatment, we attempted to give combined balneo- and chryotherapys therapy to the pateints coming to the Department of Internal Medicine of Misasa (Hot-springs) Hospital, which is located in Tottori Prefecture and is a Branch of Okayama University Hospital, over the period of the past five years, and studied the efficacy of such treatment. Our subjects were consisted of 93 cases of rheumatoid arthritis with duration of 4.8 years in average. For the balneotherapy the patients were made to rest for the first the bathing week, the combined with mud treatment and massage once or twice a day was given in the second week, and then the gold therapy was commenced. Gold thioglucose oil emulsion (Solganal B. product of Schering) was used. In the first week, 5-10 mg of Solganal B were given twice. 10 mg were given twice in the second week, and thereafter the doses were gradually increased until the total dosage reached 1.0～1.5g. By the combined balneo- and chrysotherapy applied to the 93 cases of rheumatoid arthritis, we obtained the results as follows. 1. The improvement in the erythrocyte sedimentation rate was observed in 77% of them. 2. The improvement in the CRP test was observed in 46%, but the aggravation was found in 8.7% of their conditions. 3. There were 53 cases (57%) whose RA-test was either weakened or turned negative. 4. Judging from the changes in the erythrocyte sedimentation rate and the doses of gold thioglucose given, the effects of such a treatment appear around the tenth week after the start of the treatment and it seems that the total dosage of 500 mg and over gold salt is most appropriate. 5. By the combined treatment there were 10 (48%) of 21 cases whose conditions had improved well enough as to withdraw corticosteroids treatment and remaining 11 cases (52%) who had improved to the extent where we could reduce the amount of corticosteroids. 6. By applying the evaluating system of HASHIMOTO, the efficacy rate of the treatment proves to be 89% in the cases given over 500 mg gold thioglucose, and out of these 49% showed a marked effect. Therefore, it seems that the optimal dosage is over 500 mg. 7. These results amply indicate that for the treatment of chronic rheumatoid arthritis the balneotherapy combined with some organic gold compound or salt (Solganal B in the present study) is highly beneficial. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1967-12-15 |
| Volume | volume37 |
| Start Page | 9 |
| End Page | 19 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002400927 |
| JaLCDOI | 10.18926/40181 |
|---|---|
| Title Alternative | The determination of serum triglycerides |
| FullText URL | pitsr_038_077_084.pdf |
| Author | Mifune, Masaaki| |
| Abstract | Currently accepted methods for serum triglycerides, namely, the manual modified VAN HANDEL-KAWADE method and the semi-automated LOFLAND method, were critically examined. Since the absorbents, the quality of sulfuric acid, the processes of shaking, extraction, saponification, removal of ethanol after saponification, and the stability of colored solution appear to be essential factors governing precision and accuracy of the determination, the effects of these factors were studied. It was found that the process of removal of ethanol was most important. To obtain the reproducible absorption, it is most advantageous to evaporate off ethanol from the solution of pH⋍6 on an oil bath at 101℃. As a result of re-examination on LOFLAND'S semi-automated method using a standard AutoAnalyzer, it is shown that the mixing coils can be omitted, thereby making the analysis possible in 18 -19 minutes (In the original LOFLAND'S method it takes more than 22 minutes). In addition, this modification results in smaller amount of chromotropoc acid reagent necessary (2.9 ml/min. as compared to 5 ml/min. in the original method). The determination rate in this modified method is 25 samples per hour. The average values, standard deviations, and coefficients of variance for the same serum sample for ten analyses according to the suggested manual method were 55.0 mg/dl, 1.83 mg/dl, and 4.69%, respectively, and those according to the suggested semi-automated method were 53.6 mg/dl, 1.78mg/dl and 4.68%, respectively. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1969-03-20 |
| Volume | volume38 |
| Start Page | 77 |
| End Page | 84 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002398501 |
| JaLCDOI | 10.18926/40161 |
|---|---|
| Title Alternative | Studies on the uptake of (75)Se-selenomethionine by the pancreas Attempt to augment by the effects of protocols |
| FullText URL | pitsr_040_019_031.pdf |
| Author | Tokunou, Tsuneo| |
| Abstract | Since the introduction of the pancreatic scanning using (75)Se-selenomethionine, there has been various protocols proposed to increase the pancreatic uptake of this isotope. In this experiment several protocols; as diets high carbohydrate meal, high protein meal, high fat meal, and as medicaments pancreozymin, secretin and phydroxyphenylsalicylamide (PHPS), were tested for determining the effects on the uptake of (75)Se-selenomethionine by the pancreas and the liver of the dog. The animals given protocols were sacrified at each of a number of selected times to compare P/L ratio on a percentper-gram concentration of (75)Se-selenomethionine and the total organ concentration of (75)Se-selenomethionine in the pancreas and in the liver. A controlled group of animals were fasted for 24-hour and sacrificed at each of same times. On P/L ratio basis it was found that animals with high carbohydrate meal had better ratio than those with no preparation during first 4-hour post administration. However, animals with each of high protein meal. fat meal and PI-IPS had lower ratio than those with no preparation. On the blood concentration, animals with each of high carbohydrate meal and secretin had lower variation of blood concentration than controlled group. Thus, from the results mentioned above, the protocol by high carbohydrate meal is proved to be useful in pancreatic scanning. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1971-03-26 |
| Volume | volume40 |
| Start Page | 19 |
| End Page | 31 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002398153 |
