result 5784 件
| FullText URL | K0006157_abstract_review.pdf K0006157_summary.pdf K0006157_fulltext.pdf |
|---|---|
| Author | Ryumon, Shoji| |
| Published Date | 2020-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6157号 |
| Granted Date | 2020-03-25 |
| Thesis Type | Doctor of Philosophy in Dental Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0006155_abstract_review.pdf K0006155_summary.pdf K0006155_fulltext.pdf |
|---|---|
| Author | Hasegawa, Kazuaki| |
| Published Date | 2020-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6155号 |
| Granted Date | 2020-03-25 |
| Thesis Type | Doctor of Philosophy in Dental Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0006154_abstract_review.pdf K0006154_summary.pdf K0006154_fulltext.pdf |
|---|---|
| Author | Shimizu, Rieko| |
| Published Date | 2020-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6154号 |
| Granted Date | 2020-03-25 |
| Thesis Type | Doctor of Philosophy in Dental Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0006149_abstract_review.pdf K0006149_summary.pdf K0006149_fulltext.pdf |
|---|---|
| Author | Nomura, Yu| |
| Published Date | 2020-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6149号 |
| Granted Date | 2020-03-25 |
| Thesis Type | Doctor of Philosophy in Dental Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0006148_abstract_review.pdf K0006148_summary.pdf K0006148_fulltext.pdf |
|---|---|
| Author | Yoshida, Saori| |
| Published Date | 2020-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6148号 |
| Granted Date | 2020-03-25 |
| Thesis Type | Doctor of Philosophy in Dental Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0006133_abstract_review.pdf K0006133_summary.pdf K0006133_fulltext.pdf |
|---|---|
| Author | Fukuhara, Ryuichiro| |
| Published Date | 2020-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6133号 |
| Granted Date | 2020-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0006130_abstract_review.pdf K0006130_summary.pdf K0006130_fulltext.pdf |
|---|---|
| Author | Ikegawa, Shuntaro| |
| Published Date | 2020-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6130号 |
| Granted Date | 2020-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0006128_abstract_review.pdf K0006128_summary.pdf K0006128_fulltext.pdf |
|---|---|
| Author | Ohgoshi, Yusuke| |
| Published Date | 2020-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6128号 |
| Granted Date | 2020-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | K0006116_abstract_review.pdf K0006116_summary.pdf K0006116_fulltext.pdf |
|---|---|
| Author | LA, THE MON| |
| Published Date | 2020-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6116号 |
| Granted Date | 2020-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Gion, Yuka| Okano, Mitsuhiro| Koyama, Takahisa| Oura, Tokie| Nishikori, Asami| Orita, Yorihisa| Tachibana, Tomoyasu| Marunaka, Hidenori| Makino, Takuma| Nishizaki, Kazunori| Sato, Yasuharu| |
| Keywords | mast cell eosinophilic chronic rhinosinusitis c-kit IgE |
| Published Date | 2020-03-07 |
| Publication Title | International Journal of Molecular Sciences |
| Volume | volume21 |
| Issue | issue5 |
| Publisher | MDPI |
| Start Page | 1843 |
| ISSN | 1422-0067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 by the authors. |
| File Version | publisher |
| PubMed ID | 32155995 |
| DOI | 10.3390/ijms21051843 |
| Web of Science KeyUT | 000524908500294 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms21051843 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Oka, Takashi| Matsuoka, Ken-Ichi| Utsunomiya, Atae| |
| Keywords | ATL HTLV-1 PDT PDD chemotherapy allogeneic hematopoietic cell transplantation immunotherapy GVHD ALA-PDT/PDD |
| Published Date | 2020-02-02 |
| Publication Title | Cancers |
| Volume | volume12 |
| Issue | issue2 |
| Publisher | MDPI |
| Start Page | 335 |
| ISSN | 2072-6694 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 by the authors. |
| File Version | publisher |
| PubMed ID | 32024297 |
| DOI | 10.3390/cancers12020335 |
| Web of Science KeyUT | 000522477300081 |
| Related Url | isVersionOf https://doi.org/10.3390/cancers12020335 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsumoto, Yuji| Ichikawa, Tomotsugu| Kurozumi, Kazuhiko| Otani, Yoshihiro| Fujimura, Atsushi| Fujii, Kentaro| Tomita, Yusuke| Hattori, Yasuhiko| Uneda, Atsuhito| Tsuboi, Nobushige| Kaneda, Keisuke| Makino, Keigo| Date, Isao| |
| Keywords | ANXA2 OSMR Invasion Mesenchymal transition Glioblastoma |
| Published Date | 2020-04-05 |
| Publication Title | Acta Neuropathologica Communications |
| Volume | volume8 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 42 |
| ISSN | 2051-5960 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s). 2020 |
| File Version | publisher |
| PubMed ID | 32248843 |
| DOI | 10.1186/s40478-020-00916-7 |
| Web of Science KeyUT | 000524286500001 |
| Related Url | isVersionOf https://doi.org/10.1186/s40478-020-00916-7 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Hassan, Ghmkin| Afify, Said M.| Nair, Neha| Kumon, Kazuki| Osman, Amira| Du, Juan| Mansour, Hager| Abu Quora, Hagar A.| Nawara, Hend M.| Satoh, Ayano| Zahra, Maram H.| Okada, Nobuhiro| Seno, Akimasa| Seno, Masaharu| |
| Keywords | Induced pluripotent stem cells Cancer stem cells differentiation tumor microenvironment hematopoietic cells |
| Published Date | 2019-12-29 |
| Publication Title | Cancers |
| Volume | volume12 |
| Issue | issue1 |
| Publisher | MDPI |
| Start Page | 82 |
| ISSN | 2072-6694 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2019 by the authors. |
| File Version | publisher |
| PubMed ID | 31905766 |
| DOI | 10.3390/cancers12010082 |
| Web of Science KeyUT | 000516826700082 |
| Related Url | isVersionOf https://doi.org/10.3390/cancers12010082 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sogawa, Chiharu| Eguchi, Takanori| Tran, Manh Tien| Ishige, Masayuki| Trin, Kilian| Okusha, Yuka| Taha, Eman Ahmed| Lu, Yanyin| Kawai, Hotaka| Sogawa, Norio| Takigawa, Masaharu| Calderwood, Stuart K.| Okamoto, Kuniaki| Kozaki, Ken-Ichi| |
| Keywords | drug repositioning/repurposing three-dimensional (3D) culture tumoroids dopamine transporter (DAT) benztropine signal transducer and activator of transcription (STAT) circulating tumor cell (CTC) |
| Published Date | 2020-02-24 |
| Publication Title | Cancers |
| Volume | volume12 |
| Issue | issue2 |
| Publisher | MDPI |
| Start Page | 523 |
| ISSN | 2072-6694 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2020 by the authors. |
| File Version | publisher |
| PubMed ID | 32102440 |
| DOI | 10.3390/cancers12020523 |
| Web of Science KeyUT | 000522477300269 |
| Related Url | isVersionOf https://doi.org/10.3390/cancers12020523 |
| JaLCDOI | 10.18926/AMO/58276 |
|---|---|
| FullText URL | 74_2_165.pdf |
| Author | Umemura, Hiroshi| Miura, Katsuhiro | Naruse, Hiromu| Hatta, Yoshihiro| Takei, Masami| Nakayama, Tomohiro| |
| Abstract | Hereditary hemorrhagic telangiectasia (HHT; also known as Osler-Weber-Rendu disease) is an autosomal dominant genetic disorder that causes frequent epistaxis, mucocutaneous telangiectasia, and visceral arteriovenous malformations. Four genes (ENG, ACVRL1, SMAD4, and GDF2) have been identified as pathogenic in HHT. We describe the case of a 50-year-old Japanese man highly suspected of having HHT due to recurrent epistaxis, mucocutaneous telangiectasia, and a family history. Genomic analysis revealed a novel missense mutation of c.100T>A, p.Cys34Ser in the patient’s ACVRL1 gene. We used 6 freeware programs to perform an in silico analysis of this mutation. The results demonstrated the mutation’s high pathogenicity. |
| Keywords | ACVRL1 hereditary hemorrhagic telangiectasia in silico analysis missense mutation Osler-Weber- Rendu disease |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-04 |
| Volume | volume74 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 165 |
| End Page | 169 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32341592 |
| Web of Science KeyUT | 000528278500011 |
| NAID | 120006839455 |
| JaLCDOI | 10.18926/AMO/58275 |
|---|---|
| FullText URL | 74_2_159.pdf |
| Author | Thar Htet San| Ota, Yoko| Fushimi, Soichiro| Fujisawa, Masayoshi| Yanai, Hiroyuki| Toda, Hiroko| Kunitomo, Tadayoshi| Kodama, Keisuke| Matsukawa, Akihiro| |
| Abstract | Juvenile granulosa cell tumors (JGCTs) are rare ovarian tumors with overall good prognoses. They differ from adult granulosa cell tumors (AGCTs), which are well known for late recurrence. Most JGCTs (～97%) occur in individuals <30 years old. We report a recurrent JGCT in a 40-year-old woman 5 years after initial presentation. The histological appearance and lack of 402C>G missense point mutation of FOXL2 gene (characteristic of AGCT but absent in JGCT) allowed differentiation from AGCT. This is the first comprehensive report of JGCT with late recurrence. Although rare, late recurrence of JGCT can occur; long-term surveillance is suggested. |
| Keywords | juvenile granulosa cell tumor late recurrence adult granulosa cell tumor |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-04 |
| Volume | volume74 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 159 |
| End Page | 163 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32341591 |
| Web of Science KeyUT | 000528278500010 |
| NAID | 120006839454 |
| JaLCDOI | 10.18926/AMO/58271 |
|---|---|
| FullText URL | 74_2_129.pdf |
| Author | Fukuma, Shogo| Shinya, Takayoshi| Soh, Junichi| Fukuhara, Ryuichiro| Ogawa, Nanako| Higaki, Fumiyo| Tanaka, Takehiro| Ichihara, Eiki| Hiraki, Takao| Toyooka, Shinichi| Kanazawa, Susumu| |
| Abstract | The aim of this study was to explore enhancement patterns of different types of primary lung cancers on 2-phase dynamic computed tomography (CT). This study included 217 primary lung cancer patients (141 adenocarcinomas [ADs], 48 squamous cell carcinomas [SCCs], 20 small cell lung carcinomas [SCLCs], and 8 others) who were examined using a 2-phase dynamic scan. Regions of interest were identified and mean enhancement values were calculated. After excluding the 20 SCLCs because these lesions had different clinical stages from the other cancer types, the mean attenuation values and subtractions between phases were compared between types of non-small cell lung carcinomas (NSCLCs) using the Kruskal–Wallis test. Late phase attenuation and attenuation of the late minus unenhanced phase (LMU) of SCCs were significantly higher than those of ADs (p<0.05). To differentiate SCC and AD in the late phase, a threshold of 80.21 Hounsfield units (HU) gave 52.9% accuracy. In LMU, a threshold of 52.16 HU gave 59.3% accuracy. Dynamic lung CT has the potential to aid in differentiating among NSCLC types. |
| Keywords | differentiation dynamic computed tomography primary lung cancer enhancement pattern |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-04 |
| Volume | volume74 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 129 |
| End Page | 135 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32341587 |
| Web of Science KeyUT | 000528278500006 |
| NAID | 120006839450 |
| JaLCDOI | 10.18926/AMO/58270 |
|---|---|
| FullText URL | 74_2_123.pdf |
| Author | Fukuhara, Ryuichiro| Shinya, Takayoshi| Fukuma, Shogo| Ogawa, Nanako| Masaoka, Yoshihisa| Tanaka, Takehiro| Marunaka, Hidenori| Arioka, Tadashi| Hiraki, Takao| Kaji, Mitsumasa| Kanazawa, Susumu| |
| Abstract | The aim of this study was to evaluate the ability of pretreatment 90-min 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) to predict the extranodular spread of lymph node metastases in oral squamous cell carcinoma. We retrospectively reviewed the cases of 56 patients who underwent pretreatment 18F-FDG PET/CT and surgery with neck dissection. Maximum standardized uptake value, metabolic tumor volume, and total lesion glycolysis were measured for the 56 primary sites and maximum standardized uptake value was measured for 115 lymph node levels. Extranodular spread was present at 9 lymph node levels in 7 patients. Significant differences were found in metabolic tumor volume and total lesion glycolysis of the primary site, and in lymph node maximum standardized uptake value, between patients with and without extranodular spread (p<0.05). Combining primary site total lesion glycolysis and lymph node maximum standardized uptake volume at their respective optimal cutoffs, the sensitivity, specificity, and accuracy for predicting extranodular spread were 89%, 92%, and 92%, respectively. Pretreatment 18F-FDG PET/CT is useful for predicting extranodular spread in patients with oral squamous cell carcinoma. The combined use of primary site total lesion glycolysis and lymph node maximum standardized uptake value showed greater predictive value than either predictor singly. |
| Keywords | 18F-fluorodeoxyglucose positron emission tomography/computed tomography extranodular spread metastasis oral squamous cell carcinoma |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-04 |
| Volume | volume74 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 123 |
| End Page | 128 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32341586 |
| Web of Science KeyUT | 000528278500005 |
| NAID | 120006839449 |
| JaLCDOI | 10.18926/AMO/58269 |
|---|---|
| FullText URL | 74_2_115.pdf |
| Author | Kotani, Sayoko| Kamada, Yasuhiko| Shimizu, Keiko| Sakamoto, Ai| Nakatsuka, Mikiya| Hiramatsu, Yuji| Masuyama, Hisashi| |
| Abstract | Thrombosis in decidual vessels is one of the mechanisms of pregnancy loss. However, few studies have assessed the relation between platelet activation, which is known to cause of thrombosis, and recurrent pregnancy loss (RPL). We investigated platelet activation in women with RPL compared to controls by measuring plasma levels of platelet factor 4 (PF4) and β-thromboglobulin (βTG), and assessed correlations between PF4/βTG and coagulative risk factors associated with RPL. The study group included 135 women who had experienced two or more consecutive pregnancy losses. The control group included 28 age-matched healthy women who had never experienced pregnancy loss. PF4 and βTG plasma levels were significantly higher in the women with RPL than controls (PF4: 14.0 [8.0-20.0] vs. 9.0 [6.0-12.0] ng/ml, p=0.043; βTG: 42.0 [24.3-59.8] vs. 31.5 [26.6-36.4] ng/ml, p=0.002). There was a significant association between βTG and anti-phosphatidylethanolamine antibody immunoglobulin M (aPE IgM) (p=0.048). Among the women with RPL, 18 of those who were positive for PF4 (45%) and 18 of those who were positive for βTG (37%) were negative for all known coagulative risk factors associated with RPL. Measurements of PF4 and βTG may be important because they help identify women who are at risk of RPL. |
| Keywords | recurrent pregnancy loss platelet factor 4 β-thromboglobulin platelet activation |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2020-04 |
| Volume | volume74 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 115 |
| End Page | 122 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 32341585 |
| Web of Science KeyUT | 000528278500004 |
| NAID | 120006839448 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Hirano, Yutaka| Sugimoto, Seiichiro| Yamamoto, Sumiharu| Okada, Masanori| Otani, Shinji| Ohara, Toshiaki| Yamane, Masaomi| Matsukawa, Akihiro| Oto, Takahiro| Toyooka, Shinichi| |
| Keywords | Brain dead donor Donation after cardiac death Lung transplantation Organ preservation Rejection |
| Note | This is a post-peer-review, pre-copyedit version of an article published in General Thoracic and Cardiovascular Surgery. The final authenticated version is available online at: http://dx.doi.org/10.1007/s11748-019-01181-9.| |
| Published Date | 2019-07-31 |
| Publication Title | General Thoracic and Cardiovascular Surgery |
| Volume | volume68 |
| Issue | issue1 |
| Publisher | Springer |
| Start Page | 57 |
| End Page | 62 |
| ISSN | 1863-6705 |
| NCID | AA12201344 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 31367969 |
| DOI | 10.1007/s11748-019-01181-9 |
| Web of Science KeyUT | 000511499200009 |
| Related Url | isVersionOf https://doi.org/10.1007/s11748-019-01181-9 |
