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JaLCDOI 10.18926/AMO/65976
FullText URL 77_5_537.pdf
Author Song, Qingqing| Pan, Yu| Kanazawa, Tomoyuki| Morimatsu, Hiroshi|
Abstract Elderly patients are at higher risk of postoperative hypoxemia due to their decreased respiratory function. The aim of this study was to investigate the relationship of intraoperative oxygen saturation (SpO2) and end-expiratory carbon dioxide (ETCO2) values with postoperative hypoxemia in elderly patients. The inclusion criteria were: 1) patients aged≥75 years; 2) underwent general anesthesia in non-cardiac surgery; 3) operative time longer than two hours; and 4) admission to the intensive care unit (ICU) following surgery performed between January and December 2019. Intraoperative SpO2 and ETCO2 values were collected every minute for the first two hours during surgery. The 253 patients were divided into two groups: SpO2≥92% and SpO2<92%. The time-weighted averages of intraoperative SpO2 and ETCO2 were used to compare differences between the two groups. The incidence of postoperative hypoxemia was 22.5%. For similar ventilator settings, patients with postoperative hypoxemia had lower intraoperative SpO2 and higher ETCO2 values. Sex, ASA classification, and intraoperative SpO2 were independent risk factors for postoperative hypoxemia. In conclusion, postoperative SpO2<92% was a frequent occurrence (> 20%) in elderly patients who underwent major non-cardiac surgery. Postoperative hypoxemia was associated with low intraoperative SpO2 and relatively higher ETCO2.
Keywords oxygen saturation end-expiratory carbon dioxide postoperative hypoxemia
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 537
End Page 543
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899265
Web of Science KeyUT 001108661600011
JaLCDOI 10.18926/AMO/65975
FullText URL 77_5_527.pdf
Author Ando, Miho| Hanayama, Yoshihisa| Nishimura, Yoshito| Hagiya, Hideharu| Otsuka, Fumio|
Abstract Retroperitoneal fibrosis (RPF) is a rare cause of hydronephrosis and progressive renal dysfunction with unidentified origin. RPF is categorized into idiopathic RPF with/without immunoglobulin G4 (IgG4)-related disease (IgG4-RD), and secondary RPF. Identifying the underlying cause is challenging and often associated with delayed diagnosis or therapeutic interventions. We investigated RPF’s clinical characteristics based on different etiologies and factors that may help distinguish the underlying causes. We analyzed the cases of 49 patients with RPF that was radiographically diagnosed at our institution (2008-2022). The cohort was 77.6% males; 75.5% had idiopathic RPF and 24.5% had secondary RPF. Among the idiopathic patients, 54.1% had IgG4-RD. The patients were likely to have abdominal pain, lower back pain/lumbago, and constitutional symptoms including generalized fatigue and fever. The idiopathic patients were likely to have higher serum IgG4 and IgG levels and lower serum C3 levels compared to secondary RPF. The IgG4-RPF patients were likely to have higher serum IgG4 levels and lower serum C-reactive protein, ferritin, and C3 levels compared to the idiopathic RPF patients without IgG4-RD. These findings might reflect underlying systemic inflammatory responses. Comprehensive laboratory testing, including serum inflammatory markers and immunological panels, is recommended for radiologically diagnosed RPF patients.
Keywords retroperitoneal fibrosis IgG4-related disease malignancy
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 527
End Page 536
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899264
Web of Science KeyUT 001108661600010
JaLCDOI 10.18926/AMO/65974
FullText URL 77_5_517.pdf
Author Horiguchi, Shigeru| Matsumoto, Kazuyuki| Morimoto, Kosaku| Matsumi, Akihiro| Terasawa, Hiroyuki| Fujii, Yuki| Yamazaki, Tatsuhiro| Tsutsumi, Koichiro| Kato, Hironari|
Abstract We investigated the effect of modified FOLFIRINOX (mFFX) in unresectable pancreatic cancer by retrospectively analyzing the cases of 43 patients who underwent BRCA testing (germline, n=11; somatic, n=26; both germline and somatic, n=6). The association between BRCA mutations and therapeutic effect was clarified. Six patients tested positive for germline pathogenic variants. Familial pancreatic cancer (33% vs. 3%, p=0.006) and peritoneal disseminated lesions (66% vs. 8%, p<0.001) were significantly more common in patients with germline pathogenic variants. The partial response (PR) rate was 100% in the germline BRCA-positive patients, and 27% in the germline BRCA-negative patients (p<0.001). The median progression-free survival (PFS) was not reached for any germline BRCA-positive patients but was 9.0 months for the germline BRCA-negative patients (p=0.042). Patients with stage IV BRCA-associated pancreatic cancer had better overall survival than those with non-BRCA-associated pancreatic cancer, although the difference was nonsignificant (not reached vs. 655 days, p=0.061). Our results demonstrate that a PR and prolonged PFS can be expected in germline BRCA-positive patients after treatment with mFFX. Our findings also suggest that germline BRCA pathogenic variants may be useful as biomarkers for the therapeutic effect of mFFX in patients with pancreatic cancer.
Keywords BRCA FOLFIRINOX pancreatic cancer progression-free survival pathogenic variant
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 517
End Page 525
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899263
Web of Science KeyUT 001108661600009
JaLCDOI 10.18926/AMO/65973
FullText URL 77_5_511.pdf
Author Sato, Kohei| Tsuji, Hironori| Yorimitsu, Masanori| Uehara, Takenori| Okazaki, Yuki| Takao, Shinichiro| Hata, Toshiaki| Fukuoka, Shiro| Noda, Tomoyuki| Kanda, Hideyuki| Ozaki, Toshifumi|
Abstract Sarcopenia and malnutrition are increasing in older adults and are reported risk factors for functional impairment after hip fracture surgery. This study aimed to investigate the associations between skeletal muscle mass loss, malnutrition, and postoperative walking ability in patients with hip fracture. We retrospectively reviewed patients who underwent intertrochanteric fracture surgery at our institute. The psoas muscle index, controlling nutritional status score, and functional ambulation category (FAC) were used to evaluate skeletal muscle mass, nutritional status, and walking ability, respectively. Six months after surgery, walking ability was assessed as either “gait disturbance” or “independent gait”. Multivariate binomial logistic regression analysis, with skeletal muscle mass, nutritional status, and other factors, was used to predict the risk of being assigned to the gait disturbance group. This study included 95 patients (mean age, 85.2 years; 70 women). Sixty-six patients had low skeletal muscle mass, 35 suffered from malnutrition, and 28 had both. Malnutrition and low skeletal muscle mass were significantly associated with postoperative gait disturbance (FAC < 3). Preoperative low skeletal muscle mass and malnutrition were risk factors for postoperative poor walking ability. Further preventive interventions focusing on skeletal muscle mass and nutritional status are required.
Keywords sarcopenia nutrition geriatric hip fracture psoas muscle index controlling nutritional status score
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 511
End Page 516
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899262
Web of Science KeyUT 001108661600008
JaLCDOI 10.18926/AMO/65972
FullText URL 77_5_499.pdf
Author Hatakeyama, Yuji| Hongo, Michio| Kido, Tadato| Urayama, Masakazu| Kasukawa, Yuji| Sasaki, Hiroshi| Aizawa, Toshiaki| Kudo, Daisuke| Kimura, Ryota| Ono, Yuichi| Kasama, Fumihito| Miyakoshi, Naohisa|
Abstract This study aimed to clarify neurological differences among the epiconus, conus medullaris, and cauda equina syndromes. Eighty-seven patients who underwent surgery for acute thoracolumbar spinal injuries were assessed. We defined the epiconus as the region from the terminal end of the spinal cord to the proximal 1.0 to 2.25 vertebral bodies, the conus medullaris as the region proximal to < 1.0 vertebral bodies, and the cauda equina as the distal part of the nerve roots originating from the spinal cord. On the basis of the distance from the terminal end of the spinal cord to the narrowest level of the spinal canal, the narrowest levels were ordered as follows: the epiconus followed by the conus medullaris and cauda equina. The narrowest levels were the epiconus in 22 patients, conus medullaris in 37 patients, and cauda equina in 25 patients. On admission, significantly more patients had a narrowed epiconus of Frankel grades A-C than a narrowed cauda equina. At the final follow-up, there were no significant differences in neurological recovery among those with epiconus, conus medullaris, or cauda equina syndrome. Anatomically classifying the narrowest lesion is useful for clarifying the differences and similarities among these three syndromes.
Keywords thoracolumbar spinal injury terminal end of spinal cord conus medullaris epiconus syndrome cauda equina syndrome
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 499
End Page 509
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899261
Web of Science KeyUT 001108661600007
JaLCDOI 10.18926/AMO/65971
FullText URL 77_5_491.pdf
Author Habu, Hiroshi| Takao, Soshi| Miyaji, Chikara| Matsumoto, Naomi| Aoo, Ken| Nishita, Yosuke| Tsuri, Masao| Yorifuji, Takashi|
Abstract Arts festivals have become increasingly popular in various parts of Japan in recent years. The purpose of this study was to investigate the relationships between arts festival activities participation at the Setouchi Triennale and the health of residents in the town of Naoshima. This was a cross-sectional study. Questionnaires were distributed to all residents of Naoshima who were 20 years old or older (n=2,588). We analyzed responses from 708 people. The associations between arts festival activities participation and health (measured by self-rated health) were analyzed using logistic regression analysis as the primary outcome. Kessler’s psychological distress scale scores were also analyzed in the same manner as the primary outcome. The participating group had an adjusted odds ratio of 1.86 (95% confidence interval: 1.03-3.33) for higher self-rated health compared with those who did not participate. Kessler’s psychological distress scale results showed that the participating group had an adjusted odds ratio of 3.23 (95% confidence interval: 1.19-8.81) for lower psychological distress compared with those who did not participate. In conclusion, arts festival activities participation was associated with higher self-rated health and lower psychological distress. However, caution must be taken in regard to generalizability and causality when interpreting these results.
Keywords art arts in public health arts festival self-rated health Setouchi Triennale
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 491
End Page 497
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899260
Web of Science KeyUT 001108661600006
JaLCDOI 10.18926/AMO/65970
FullText URL 77_5_479.pdf
Author Murata, Akiko| Matsumoto, Naomi| Miyaji, Chikara| Takao, Soshi| Yorifuji, Takashi|
Abstract For decades, the notion has persisted in developed countries that exclusive care by the mothers is best for the development of children up to 3 years of age. To examine the veracity of this “myth of the first three years” in Japan, we examined the effects of childcare facility use for children younger than 3 years on their development using the cohorts of the Longitudinal Survey of Newborns in the 21st Century conducted in Japan. Of the 47,015 respondents to the survey, we studied the children of 5,508 mothers with university/professional education to evaluate the relationships between primary early (< 2.5 years) childcare providers during weekday daytime hours and specific development indices for the ages of 2.5, 5.5, and 8 years. At the age of 2.5 and 5.5 years, children attending childcare facilities were judged as having more advanced developmental behaviors by their parents, such as being able to compose a two-word sentence (adjusted odds ratio [aOR]: 0.22) or to express emotions (aOR: 0.81), compared with those cared for by mothers. However, at the age of 8 years, children who attended childcare facilities as infants < 2.5 years showed more aggressive behavior in interrupting people (aOR: 1.20) and causing disturbances in public (aOR: 1.26) than those cared for by mothers (after adjustment for numerous child and parental factors). Although these results are generally consistent with previous studies, issues potentially involved with problem behavior such as quality of childcare require further investigation, as does the case of children of mothers with more modest educational attainment.
Keywords “myth of the first three years” childcare child development problem behavior educational attainment
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 479
End Page 490
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899259
Web of Science KeyUT 001108661600005
JaLCDOI 10.18926/AMO/65969
FullText URL 77_5_471.pdf
Author Oka, Shohei| Harada, Keita| Yamamoto, Shumpei| Yasutomi, Eriko| Igawa, Shoko| Ohmori, Masayasu| Hirai, Mami| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Hiraoka, Sakiko| Okada, Hiroyuki|
Abstract Although the clinical usefulness of colonoscopy has been established, the procedure remains painful for many patients. This study was designed to clarify the factors predicting colonoscopy-related pain. We evaluated 283 consecutive patients who completed a first-ever, total colonoscopy without sedatives or analgesics. The severity of pain symptoms was evaluated by a numeric rating scale (NRS) in a questionnaire immediately after the colonoscopy. Patient backgrounds and endoscopic findings were analyzed to evaluate their association with pain. Out of 283 patients, 53 scored their pain 0-1 on the NRS while 48 scored it 6-10. We defined the colonoscopies of the former and latter patients as painless and painful, respectively, and compared the two. Multivariate analyses revealed that low body weight (OR 4.95, 95%CI 1.89-12.99) and longer intubation time (OR 3.63, 95%CI 1.46-9.03) were significant risk factors for painful colonoscopy. To identify factors contributing to the increased intubation time, we divided subjects into short- and long-intubation-time groups based on a median insertion time of 7 min. Older age (OR 2.28, 95%CI 1.31-3.98), previous abdominal surgery (OR 1.93, 95%CI 1.13-3.32) and findings of invasive cancer (OR 10.90, 95%CI 1.34-88.90) were significant factors for longer intubation time.
Keywords colonoscopy colonoscopy-related pain comfortable colonoscopy
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 471
End Page 478
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899258
Web of Science KeyUT 001108661600004
JaLCDOI 10.18926/AMO/65968
FullText URL 77_5_461.pdf
Author Homma, Daisuke| Minato, Izumi| Imai, Norio| Miyasaka, Dai| Sakai, Yoshinori| Horigome, Yoji| Suzuki, Hayato| Dohmae, Yoichiro| Endo, Naoto|
Abstract This study aimed to determine which muscle the gluteus maximus, gluteus medius, gluteus minimus (Gmin), or tensor fasciae latae (TFL) contributes most to hip abduction strength and to identify effective sites for cross-sectional area (CSA) Gmin and TFL measurement in hip osteoarthritis (OAhip) patients. Twenty-eight patients with OAhip were included. The muscle CSA and volume were determined using magnetic resonance imaging. Peak isometric strength was determined using hand-held dynamometry. Muscle volumes were normalized to the total muscle volume of hip abductors. Multiple regression analysis was performed. The difference between the CSA of Gmin and TFL was calculated, and correlations with volume and muscle strength were determined. Gmin volume was related to abductor muscle strength (p=0.042). The peak CSA of the Gmin correlated with muscle volume and strength. The CSA of the TFL correlated with volume, with no difference between the CSA of the most protruding part of the lesser trochanter and peak CSA. Gmin volume was strongly related to abductor muscle strength. Peak CSA is a useful parameter for assessing the CSA of the Gmin among patients with OAhip. The CSA of the TFL should be measured at the most protruding part of the lesser trochanter.
Keywords gluteus minimus tensor fasciae latae cross-sectional area muscle volume hip osteoarthritis
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 461
End Page 469
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899257
Web of Science KeyUT 001108661600003
JaLCDOI 10.18926/AMO/65967
FullText URL 77_5_451.pdf
Author Okita, Atsushi| Tsukuda, Kazunori| Ino, Hideo| Mitsui, Ema| Ikeya, Nanami| Yamamoto, Sumiharu| Yokoyama, Nobuji| Bulin, Aubra|
Abstract Using a Collaborative Action Research model, our research team established a one-month clinical resident training program for first- and second-year clinical residents. We created and implemented an assessment rubric to assess the residents’ progress toward independent practice in surgery, and thereby, to evaluate the program itself. The program included training in three areas: basic techniques and procedures in the operating room, surgical ward management, and academic activities. The rubric measured the residents’ performance according to three achievement levels: Level 1 (demonstration), Level 2 (active help) and Level 3 (passive help). The program and rubric implementation began in June 2019 and continued until March 2020, when the program outcomes and shortcomings were analyzed. Among nineteen clinical residents, a total of nine clinical residents participated in the study. Most participants reached achievement Level 3 for their performance of basic techniques in the operating room. Finally, we discussed ideas for improvement and drafted plans for an improved rubric to complete the action research cycle. Our research team found the rubric to be a useful tool in evaluating the status of the new clinical resident training program.
Keywords resident program rubric assessment general surgery action research
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 451
End Page 460
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899256
Web of Science KeyUT 001108661600002
JaLCDOI 10.18926/AMO/65966
FullText URL 77_5_443.pdf
Author Miyaji, Chikara| Takao, Soshi| Habu, Hiroshi| Matsumoto, Naomi| Aoo, Ken| Nishita, Yosuke| Tsuri, Masao| Yorifuji, Takashi|
Abstract This study examined whether participation in an art project was associated with higher social capital (SC). We conducted a questionnaire survey from November 2021 to March 2022 among residents aged 20 years or older of Naoshima, an island in Kagawa Prefecture, Japan. Before the survey, the Setouchi Triennale had been held on Naoshima four times, starting in 2010. We calculated propensity scores for Triennale participation and performed propensity score matching. We then compared cognitive and structural SC by Triennale participation and found significant differences, respectively. We adopted a conditional ordered logistic regression analysis with propensity score matching for cognitive or structural SC, and found adjusted odd ratios of 2.913 (95%CI, 1.846-4.596) for cognitive SC and 4.535 (95%CI, 2.839-7.244) for structural SC. Our findings suggest that Triennale participation enhanced the cognitive aspect of SC while also building structural SC.
Keywords social capital art project propensity score matching
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 443
End Page 449
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899255
Web of Science KeyUT 001108661600001
FullText URL fulltext20231017-02.pdf
Author Takamura, Hiroyoshi| Hattori, Kosuke| Ohashi, Takumi| Otsu, Taichi| Kadota, Isao|
Published Date 2023-09-29
Publication Title Organic and Biomolecular Chemistry
Publisher Royal Society of Chemistry (RSC)
ISSN 1477-0520
NCID AA1168650X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Royal Society of Chemistry 2023
File Version publisher
PubMed ID 37791452
DOI 10.1039/d3ob01420g
Web of Science KeyUT 001074599100001
Related Url isVersionOf https://doi.org/10.1039/d3ob01420g
FullText URL fulltext.pdf
Author Okawa, Yukari| Suzuki, Etsuji| Mitsuhashi, Toshiharu| Tsuda, Toshihide| Yorifuji, Takashi|
Note The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-40300-8|
Published Date 2023-08-23
Publication Title Scientific Reports
Volume volume13
Issue issue1
Publisher Nature Portfolio
Start Page 13770
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023
File Version publisher
PubMed ID 37612346
DOI 10.1038/s41598-023-40300-8
Web of Science KeyUT 001067659900074
Related Url isVersionOf https://doi.org/10.1038/s41598-023-40300-8
FullText URL fulltext20231012-01.pdf
Author Matsuda, Naoki| Yamamoto, Hiromasa| Habu, Tomohiro| Iwata, Kazuma| Matsubara, Kei| Tanaka, Shin| Hashimoto, Kohei| Shien, Kazuhiko| Suzawa, Ken| Miyoshi, Kentaroh| Toji, Tomohiro| Okazaki, Mikio| Sugimoto, Seiichiro| Takahashi, Katsuhito| Toyooka, Shinichi|
Note The version of record of this article, first published in Annals of Surgical Oncology, is available online at Publisher’s website: http://dx.doi.org/10.1245/s10434-023-14176-x|
Published Date 2023-09-01
Publication Title Annals of Surgical Oncology
Volume volume30
Issue issue13
Publisher Springer Science and Business Media LLC
Start Page 8727
End Page 8734
ISSN 1068-9265
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023
File Version publisher
PubMed ID 37658268
DOI 10.1245/s10434-023-14176-x
Web of Science KeyUT 001060201900008
Related Url isVersionOf https://doi.org/10.1245/s10434-023-14176-x
FullText URL fulltext.pdf
Author Khazan, Negar| Kim, Kyu Kwang| Hansen, Jeanne N.| Singh, Niloy A.| Moore, Taylor| Snyder, Cameron W. A.| Pandita, Ravina| Strawderman, Myla| Fujihara, Michiko| Takamura, Yuta| Jian, Ye| Battaglia, Nicholas| Yano, Naohiro| Teramoto, Yuki| Arnold, Leggy A.| Hopson, Russell| Kishor, Keshav| Nayak, Sneha| Ojha, Debasmita| Sharon, Ashoke| Ashton, John M.| Wang, Jian| Milano, Michael T.| Miyamoto, Hiroshi| Linehan, David C.| Gerber, Scott A.| Kawar, Nada| Singh, Ajay P.| Tabdanov, Erdem D.| Dokholyan, Nikolay V.| Kakuta, Hiroki| Jurutka, Peter W.| Schor, Nina F.| Rowswell-Turner, Rachael B.| Singh, Rakesh K.| Moore, Richard G.|
Published Date 2022-04-11
Publication Title Journal of Medicinal Chemistry
Volume volume65
Issue issue8
Publisher American Chemical Society (ACS)
Start Page 6039
End Page 6055
ISSN 0022-2623
NCID AA00702411
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Authors.
File Version publisher
PubMed ID 35404047
DOI 10.1021/acs.jmedchem.1c01878
Web of Science KeyUT 000797573100012
Related Url isVersionOf https://doi.org/10.1021/acs.jmedchem.1c01878
FullText URL fulltext.pdf
Author Shuku, Takayuki| Ropponen, Janne| Juntunen, Janne| Suito, Hiroshi|
Published Date 2022-01-18
Publication Title Meteorology and Atmospheric Physics
Volume volume134
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 18
ISSN 0177-7971
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022
File Version publisher
DOI 10.1007/s00703-021-00857-3
Web of Science KeyUT 000743932500001
Related Url isVersionOf https://doi.org/10.1007/s00703-021-00857-3
FullText URL fulltext.pdf
Author Shinoda, Sumio|
Keywords COVID-19 SARS-CoV-2 vaccine Spanish flu influenza
Published Date 2022-01-30
Publication Title Journal of Disaster Research
Volume volume17
Issue issue1
Publisher Fuji Technology Press Ltd.
Start Page 65
End Page 72
ISSN 1883-8030
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Fuji Technology Press Ltd.
File Version publisher
DOI 10.20965/jdr.2022.p0065
Web of Science KeyUT 000748695600008
Related Url isVersionOf https://doi.org/10.20965/jdr.2022.p0065
FullText URL fulltext.pdf
Author Shimooka, So| Akagi, Tetsuya| Dohta, Shujiro| Shinohara, Takashi| Kobayashi, Takumi|
Keywords spiral shaped soft holding actuator extension type flexible pneumatic actuator circumference restraint mechanism analytical model
Published Date 2022-04-20
Publication Title Journal of Robotics and Mechatronics
Volume volume34
Issue issue2
Publisher Fuji Technology Press Ltd.
Start Page 373
End Page 381
ISSN 1883-8049
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Fuji Technology Press Ltd.
File Version publisher
DOI 10.20965/jrm.2022.p0373
Web of Science KeyUT 000795878000037
Related Url isVersionOf https://doi.org/10.20965/jrm.2022.p0373
FullText URL fulltext.pdf
Author Shikata, Kenichi| Ito, Sadayoshi| Kashihara, Naoki| Nangaku, Masaomi| Wada, Takashi| Okuda, Yasuyuki| Sawanobori, Tomoko| Sugimoto, Kotaro|
Keywords Esaxerenone Potassium Sodium-glucose transporter 2 inhibitor
Published Date 2022-04-21
Publication Title Journal of Diabetes Investigation
Volume volume13
Issue issue7
Publisher Wiley
Start Page 1190
End Page 1202
ISSN 2040-1116
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Authors.
File Version publisher
PubMed ID 35199478
DOI 10.1111/jdi.13778
Web of Science KeyUT 000789571800001
Related Url isVersionOf https://doi.org/10.1111/jdi.13778
FullText URL fulltext.pdf
Author Nagahata, Taichi| Tsujino, Yoshio| Takayama, Eiji| Hikasa, Haruka| Satoh, Ayano|
Keywords skin sensitization immunotoxicity interleukin-2 promoter Jurkat T-cell activation
Published Date 2021-11-08
Publication Title Biomedical Reports
Volume volume16
Issue issue1
Publisher Spandidos Publications
Start Page 3
ISSN 2049-9434
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Nagahata et al.
File Version publisher
PubMed ID 34820126
DOI 10.3892/br.2021.1486
Web of Science KeyUT 000721724000001
Related Url isVersionOf https://doi.org/10.3892/br.2021.1486