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FullText URL fulltext20240808-01.pdf
Author Kawase, Tomoka| Debnath, Anusuya| Mizuno, Tamaki| Miyake, Yui|
Keywords Vibrio vulnificus serine protease intermolecular chaperone cell-free translation system
Published Date 2022-11-01
Publication Title Biological and Pharmaceutical Bulletin
Volume volume45
Issue issue11
Publisher Pharmaceutical Society of Japan
Start Page 1596
End Page 1601
ISSN 0918-6158
NCID AA10885497
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Pharmaceutical Society of Japan
File Version publisher
PubMed ID 36328494
DOI 10.1248/bpb.b22-00106
Web of Science KeyUT 000886101900001
Related Url isVersionOf https://doi.org/10.1248/bpb.b22-00106
FullText URL fulltext.pdf
Author Moriya, Yuto| Kubota, Sho| Iijima, Yuta| Takasugi, Nobumasa| Uehara, Takashi|
Keywords nitric oxide human small airway epithelial cell epigenetics DNA methylation carbonic anhydrase 9 hypoxia-inducible factor 1 alpha
Published Date 2024-06-05
Publication Title Biological and Pharmaceutical Bulletin
Volume volume47
Issue issue6
Publisher Pharmaceutical Society of Japan
Start Page 1119
End Page 1122
ISSN 0918-6158
NCID AA10885497
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Author(s)
File Version publisher
PubMed ID 38839363
DOI 10.1248/bpb.b24-00241
Web of Science KeyUT 001241469600003
Related Url isVersionOf https://doi.org/10.1248/bpb.b24-00241
FullText URL fulltext20240801-01.pdf
Author Sekiguchi, Manabu| Reinhard, Nils| Fukuda, Ayumi| Katoh, Shun| Rieger, Dirk| Helfrich-Förster, Charlotte| Yoshii, Taishi|
Keywords period GAL4-UAS clock neuron activity rhythm two-oscillator model
Note This is an Accepted Manuscript published by SAGE Publications.|
Published Date 2024-07-31
Publication Title Journal of Biological Rhythms
Volume volume39
Issue issue5
Publisher SAGE Publications
Start Page 463
End Page 483
ISSN 0748-7304
NCID AA10667882
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Author(s).
File Version author
PubMed ID 39082442
DOI 10.1177/07487304241263130
Web of Science KeyUT 001282701800001
Related Url isVersionOf https://doi.org/10.1177/07487304241263130
FullText URL fulltext20240716-03.pdf
Author Nakanishi, Kotaro| Kojima, Keiichi| Sowa, Yoshiyuki| Sudo, Yuki|
Note This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Physical Chemistry B, copyright © 2024 American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.jpcb.4c03027.| This fulltext file will be available in Aug. 2025.|
Published Date 2024-07-01
Publication Title The Journal of Physical Chemistry B
Volume volume128
Issue issue27
Publisher American Chemical Society (ACS)
Start Page 6509
End Page 6517
ISSN 1520-6106
NCID AA11114073
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 American Chemical Society
File Version author
PubMed ID 38949422
DOI 10.1021/acs.jpcb.4c03027
Web of Science KeyUT 001261316100001
Related Url isVersionOf https://doi.org/10.1021/acs.jpcb.4c03027
FullText URL fulltext.pdf
Author Tokuyama, Yuka| Mori, Kanae| Isobe, Midori| Terato, Hiroaki|
Keywords base damage mutation gamma-rays heavy ion beam
Published Date 2024-06-28
Publication Title Journal of Radiation Research
Volume volume65
Issue issue4
Publisher Oxford University Press
Start Page 491
End Page 499
ISSN 0449-3060
NCID AA00705792
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024.
File Version publisher
PubMed ID 38940734
DOI 10.1093/jrr/rrae050
Web of Science KeyUT 001257220300001
Related Url isVersionOf https://doi.org/10.1093/jrr/rrae050
FullText URL fulltext.pdf
Author Li, Yuying| Wang, Qiong| Jia, Huimin| Ishikawa, Kazuya| Kosami, Ken-Ichi| Ueba, Takahiro| Tsujimoto, Atsumi| Yamanaka, Miki| Yabumoto, Yasuyuki| Miki, Daisuke| Sasaki, Eriko| Fukao, Yoichiro| Fujiwara, Masayuki| Kaneko-Kawano, Takako| Tan, Li| Kojima, Chojiro| Wing, Rod A.| Sebastian, Alfino| Nishimura, Hideki| Fukada, Fumi| Niu, Qingfeng| Shimizu, Motoki| Yoshida, Kentaro| Terauchi, Ryohei| Shimamoto, Ko| Kawano, Yoji|
Note The version of record of this article, first published in Nature Communications, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41467-024-48943-5|
Published Date 2024-05-30
Publication Title Nature Communications
Volume volume15
Issue issue1
Publisher Nature Portfolio
Start Page 4610
ISSN 2041-1723
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 38816417
DOI 10.1038/s41467-024-48943-5
Web of Science KeyUT 001236316700012
Related Url isVersionOf https://doi.org/10.1038/s41467-024-48943-5
FullText URL fulltext.pdf
Author Takamura, Hiroyoshi| Sugitani, Yuki| Morishita, Ryohei| Yorisue, Takefumi| Kadota, Isao|
Published Date 2024
Publication Title Organic & Biomolecular Chemistry
Volume volume22
Issue issue28
Publisher Royal Society of Chemistry (RSC)
Start Page 5739
End Page 5747
ISSN 1477-0520
NCID AA1168650X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Royal Society of Chemistry 2024
File Version publisher
PubMed ID 38828517
DOI 10.1039/d4ob00698d
Web of Science KeyUT 001237473000001
Related Url isVersionOf https://doi.org/10.1039/d4ob00698d
FullText URL fulltext.pdf
Author Chadani, Yuhei| Yamanouchi, Shun| Uemura, Eri| Yamasaki, Kohei| Niwa, Tatsuya| Ikeda, Toma| Kurihara, Miku| Iwasaki, Wataru| Taguchi, Hideki|
Published Date 2024-04-25
Publication Title Nucleic Acids Research
Volume volume52
Issue issue10
Publisher Oxford University Press
Start Page 5825
End Page 5840
ISSN 0305-1048
NCID AA00760269
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024.
File Version publisher
PubMed ID 38661232
DOI 10.1093/nar/gkae309
Web of Science KeyUT 001207872100001
Related Url isVersionOf https://doi.org/10.1093/nar/gkae309
FullText URL fulltext.pdf
Author Matsushima, Ryo| Hisano, Hiroshi| Galis, Ivan| Miura, Satoko| Crofts, Naoko| Takenaka, Yuto| Oitome, Naoko F.| Ishimizu, Takeshi| Fujita, Naoko| Sato, Kazuhiro|
Note The version of record of this article, first published in Theoretical and Applied Genetics, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00122-023-04339-5|
Published Date 2023-04
Publication Title Theoretical and Applied Genetics
Volume volume136
Issue issue4
Publisher Springer Science and Business Media LLC
Start Page 94
ISSN 0040-5752
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023
File Version publisher
PubMed ID 37010621
DOI 10.1007/s00122-023-04339-5
Web of Science KeyUT 000962880600001
Related Url isVersionOf https://doi.org/10.1007/s00122-023-04339-5
JaLCDOI 10.18926/AMO/66927
FullText URL 78_2_185.pdf
Author Takahashi, Hiroko| Eguchi, Jun| Watanabe, Mayu| Nakayama, Masanori| Wada, Jun|
Abstract The global pandemic of coronavirus infection 2019 (COVID-19) was an unprecedented public health emergency. Several clinical studies reported that heart disease, lung disease, diabetes, hypertension, dyslipidemia, and obesity are critical risk factors for increased severity of and hospitalization for COVID-19. This is largely because patients with these underlying medical conditions can show poor immune responses to the COVID-19 vaccinations. Diabetes is one of the underlying conditions most highly associated with COVID-19 susceptibility and is considered a predictor of poor prognosis of COVID-19. We therefore investigated factors that influence the anti-SARS-CoV-2 spike IgG antibody titer after three doses of vaccination in patients with type 2 diabetes. We found that obesity was associated with low anti-SARS-CoV-2 spike IgG antibody titers following three-dose vaccination in type 2 diabetics. Obese patients with type 2 diabetes may have attenuated vaccine efficacy and require additional vaccination; continuous infection control should be considered in such patients.
Keywords obesity type 2 diabetes COVID-19 vaccination
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 185
End Page 191
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688836
Web of Science KeyUT 001227932200002
JaLCDOI 10.18926/AMO/66924
FullText URL 78_2_151.pdf
Author Komatsubara, Tadashi| Tazawa, Hiroshi| Hasei, Joe| Omori, Toshinori| Sugiu, Kazuhisa| Mochizuki, Yusuke| Demiya, Koji| Yoshida, Aki| Fujiwara, Tomohiro| Kunisada, Toshiyuki| Urata, Yasuo| Kagawa, Shunsuke| Ozaki, Toshifumi| Fujiwara, Toshiyoshi|
Abstract Soft-tissue sarcoma (STS) is a heterogeneous group of rare tumors originating predominantly from the embryonic mesoderm. Despite the development of combined modalities including radiotherapy, STSs are often refractory to antitumor modalities, and novel strategies that improve the prognosis of STS patients are needed. We previously demonstrated the therapeutic potential of two telomerase-specific replication-competent oncolytic adenoviruses, OBP-301 and tumor suppressor p53-armed OBP-702, in human STS cells. Here, we demonstrate in vitro and in vivo antitumor effects of OBP-702 in combination with ionizing radiation against human STS cells (HT1080, NMS-2, SYO-1). OBP-702 synergistically promoted the antitumor effect of ionizing radiation in the STS cells by suppressing the expression of B-cell lymphoma-X large (BCL-xL) and enhancing ionizing radiation-induced apoptosis. The in vivo experiments demonstrated that this combination therapy significantly suppressed STS tumors’ growth. Our results suggest that OBP-702 is a promising antitumor reagent for promoting the radiosensitivity of STS tumors.
Keywords soft-tissue sarcoma radiotherapy oncolytic adenovirus p53 BCL-xL
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 151
End Page 161
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688833
Web of Science KeyUT 001229151800007
JaLCDOI 10.18926/AMO/66915
FullText URL 78_2_123.pdf
Author Saeki, Kyosuke| Fujiwara, Hideaki| Seike, Keisuke| Kuroi, Taiga| Nishimori, Hisakazu| Tanaka, Takehiro| Matsuoka, Ken-ichi| Fujii, Nobuharu| Maeda, Yoshinobu|
Abstract Chronic graft-versus-host disease (GVHD) is a major cause of late death and morbidity following allogeneic hematopoietic cell transplantation (HCT), but its pathogenesis remains unclear. Recently, haplo-identical HCT with post-transplant cyclophosphamide (Haplo-HCT with PTCY) was found to achieve a low incidence rate of acute GVHD and chronic GVHD. However, while the pathogenesis of acute GVHD following Haplo-HCT with PTCY has been well investigated, that of chronic GVHD remains to be elucidated, especially in HLA-matched HCT with PTCY. Based on its safety profile, PTCY is currently applied for the human leucocyte antigen (HLA)-matched HCT setting. Here, we investigated the mechanisms of chronic GVHD following HLA-matched HCT with PTCY using a well-defined mouse chronic GVHD model. PTCY attenuated clinical and pathological chronic GVHD by suppressing effector T-cells and preserving regulatory T-cells compared with a control group. Additionally, we demonstrated that cyclosporine A (CsA) did not show any additional positive effects on attenuation of GVHD in PTCY-treated recipients. These results suggest that monotherapy with PTCY without CsA could be a promising strategy for the prevention of chronic GVHD following HLA-matched HCT.
Keywords GVHD posttransplant cyclophosphamide hematopoietic cell transplantation HLA-identical
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 123
End Page 134
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688830
Web of Science KeyUT 001229151800004
FullText URL fulltext.pdf
Author Fujioka, Haruna| Marchand, Manon| LeBoeuf, Adria C.|
Keywords mandibular pseudotrophallaxis social bucket liquid transportation liquid collection optimal foraging theory biophysics
Published Date 2023-06-14
Publication Title Proceedings of the Royal Society B: Biological Sciences
Volume volume290
Issue issue2000
Publisher The Royal Society
Start Page 20230549
ISSN 0962-8452
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Authors.
File Version publisher
PubMed ID 37312541
DOI 10.1098/rspb.2023.0549
Web of Science KeyUT 001010884000013
Related Url isVersionOf https://doi.org/10.1098/rspb.2023.0549
FullText URL fulltext.pdf
Author Kadoya, Koichi| Hara, Emilio Satoshi| Okada, Masahiro| Jiao, Yu Yang| Nakano, Takayoshi| Sasaki, Akira| Matsumoto, Takuya|
Keywords trabecular bone calcospherites cell membrane nano fragments three dimensionalization bone tissue synthesis
Published Date 2022-11-02
Publication Title Regenerative Biomaterials
Volume volume10
Publisher Oxford University Press
Start Page rbac088
ISSN 2056-3418
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022.
File Version publisher
PubMed ID 36683756
DOI 10.1093/rb/rbac088
Web of Science KeyUT 001187808700008
Related Url isVersionOf https://doi.org/10.1093/rb/rbac088
FullText URL fulltext.pdf
Author Sato, Keita| Yamashita, Takahiro| Ohuchi, Hideyo|
Keywords G protein G protein−coupled receptor (GPCR) photoreceptor rhodopsin calcium intracellular release protein−protein interaction signal transduction nonvisual photoreception
Published Date 2023-08
Publication Title Journal of Biological Chemistry
Volume volume299
Issue issue8
Publisher Elsevier
Start Page 105020
ISSN 1083-351X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Authors.
File Version publisher
PubMed ID 37423300
DOI 10.1016/j.jbc.2023.105020
Web of Science KeyUT 001166411500001
Related Url isVersionOf https://doi.org/10.1016/j.jbc.2023.105020
FullText URL fulltext.pdf
Author Kamada, Shinji| Nakajima, Yoshiki| Shen, Jian-Ren|
Keywords Photosystem II photosynthesis electron transfer structural biology crystal structure electron acceptor
Published Date 2023-07
Publication Title Journal of Biological Chemistry
Volume volume299
Issue issue7
Publisher Elsevier
Start Page 104839
ISSN 1083-351X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Authors.
File Version publisher
PubMed ID 37209822
DOI 10.1016/j.jbc.2023.104839
Web of Science KeyUT 001166336800001
Related Url isVersionOf https://doi.org/10.1016/j.jbc.2023.104839
FullText URL fulltext20240226-01.pdf
Author Kawazu, Toshiyuki| Takeshita, Yohei| Fujikura, Mamiko| Okada, Shunsuke| Hisatomi, Miki| Asaumi, Junichi|
Keywords Deep neural networks Caries detection Domain-Specific transfer learning Panoramic tomography
Note The version of record of this article, first published in Journal of Medical and Biological Engineering, is available online at Publisher’s website: http://dx.doi.org/10.1007/s40846-024-00848-w|
Published Date 2024-02-13
Publication Title Journal of Medical and Biological Engineering
Volume volume44
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 43
End Page 48
ISSN 1609-0985
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
DOI 10.1007/s40846-024-00848-w
Web of Science KeyUT 001160649900001
Related Url isVersionOf https://doi.org/10.1007/s40846-024-00848-w
FullText URL fulltext.pdf
Author Kanao, Tadayoshi|
Keywords tetrathionate hydrolase reduced inorganic sulfur compounds dissimilatory sulfur metabolism S4-intermediate pathway acidophiles chemoautotroph
Published Date 2024-01-29
Publication Title Frontiers in Microbiology
Volume volume15
Publisher Frontiers Media
Start Page 1338669
ISSN 1664-302X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Kanao.
File Version publisher
PubMed ID 38348185
DOI 10.3389/fmicb.2024.1338669
Web of Science KeyUT 001160607900001
Related Url isVersionOf https://doi.org/10.3389/fmicb.2024.1338669
FullText URL srfa_113_041_048.pdf
Author Tanaka, Yu| Watanabe, Tomoya| Katsura, Keisuke| Tsujimoto, Yasuhiro| Takai, Toshiyuki| Tanaka, Takashi Sonam Tashi| Kawamura, Kensuke| Saito, Hiroki| Homma, Koki| Mairoua, Salifou Goube| Ahouanton, Kokou| Ibrahim, Ali| Senthilkumar, Kalimuthu| Semwal, Vimal Kumar| Matute, Eduardo Jose Graterol| Corredor, Edgar| El-Namaky, Raafat| Manigbas, Norvie| Quilang, Eduardo Jimmy P.| Iwahashi, Yu| Nakajima, Kota| Takeuchi, Eisuke| Saito, Kazuki|
Abstract Rice (Oryza sativa L.) is one of the most important cereals, which provides 20% of the world’s food energy. However, its productivity is poorly assessed especially in the global South. Here, we provide a first study to perform a deep learning-based approach for instantaneously estimating rice yield using RGB images. During ripening stage and at harvest, over 22,000 digital images were captured vertically downwards over the rice canopy from a distance of 0.8 to 0.9m at 4,820 harvesting plots having the yield of 0.1 to 16.1 t ha-1 across six countries in Africa and Japan. A convolutional neural network (CNN) applied to these data at harvest predicted 68% variation in yield with a relative root mean square error (rRMSE) of 0.22. Even when the resolution of images was reduced (from 0.2 to 3.2cm pixel-1 of ground sampling distance), the model could predict 57% variation in yield, implying that this approach can be scaled by use of unmanned aerial vehicles. Our work offers low-cost, hands-on, and rapid approach for high throughput phenotyping, and can lead to impact assessment of productivity-enhancing interventions, detection of fields where these are needed to sustainably increase crop production.
Keywords Rice (Oryza sativa L.) rough grain yield convolutional neural network RGB images UAV
Publication Title Scientific Reports of the Faculty of Agriculture, Okayama University
Published Date 2024-02-01
Volume volume113
Start Page 41
End Page 48
ISSN 2186-7755
language English
File Version publisher
FullText URL fulltext20240130-01.pdf
Author Miyazaki, Yusuke| Shinoda, Wataru|
Note This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Chemical Information and Modeling, copyright © 2023 American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.jcim.3c01611.| This fulltext file will be available in Dec. 2024.|
Published Date 2023-12-29
Publication Title Journal of Chemical Information and Modeling
Volume volume64
Issue issue2
Publisher American Chemical Society (ACS)
Start Page 532
End Page 542
ISSN 1549-9596
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 American Chemical Society
File Version author
PubMed ID 38156656
DOI 10.1021/acs.jcim.3c01611
Web of Science KeyUT 001146739900001
Related Url isVersionOf https://doi.org/10.1021/acs.jcim.3c01611