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JaLCDOI 10.18926/AMO/66151
FullText URL 77_6_595.pdf
Author Bando, Takashi| Chuma, Masayuki| Hamano, Hirofumi| Niimura, Takahiro| Okada, Naoto| Kondo, Masateru| Izumi, Yuki| Ishida, Shunsuke| Yoshioka, Toshihiko| Asada, Mizuho| Zamami, Yoshito| Takechi, Kenshi| Goda, Mitsuhiro| Miyata, Koji| Yagi, Kenta| Izawa-Ishizawa, Yuki| Azuma, Momoyo| Yanagawa, Hiroaki| Tasaki, Yoshikazu| Ishizawa, Keisuke|
Abstract There is a growing concern about the relationship between vancomycin-associated nephrotoxicity (VAN) and concomitant use of nephrotoxins. We examined this relationship by combined retrospective analyses of two real-world databases. Initially, the FDA Adverse Event Reporting System (FAERS) was analyzed for the effects of concomitant use of one or more nephrotoxins on VAN and the types of combinations of nephrotoxins that exacerbate VAN. Next, electronic medical records (EMRs) of patients who received vancomycin (VCM) at Tokushima University Hospital between January 2006 and March 2019 were examined to confirm the FAERS analysis. An elevated reporting odds ratio (ROR) was observed with increases in the number of nephrotoxins administered (VCM + one nephrotoxin, adjusted ROR (95% confidence interval [CI]) 1.67 [1.51-1.85]; VCM + ≥2 nephrotoxins, adjusted ROR [95% CI] 1.54 [1.37-1.73]) in FAERS. EMRs analysis showed that the number of nephrotoxins was associated with higher incidences of VAN [odds ratio: 1.99; 95% CI: 1.42-2.78]. Overall, concomitant use of nephrotoxins was associated with an increased incidence of VAN, especially when at least one of those nephrotoxins was a renal hypoperfusion medication (furosemide, non-steroidal anti-inflammatory drugs, and vasopressors). The concomitant use of multiple nephrotoxins, especially including renal hypoperfusion medication, should be avoided to prevent VAN.
Keywords vancomycin-associated nephrotoxicity polypharmacy nephrotoxin spontaneous adverse event reporting database electronic medical records
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-12
Volume volume77
Issue issue6
Publisher Okayama University Medical School
Start Page 595
End Page 605
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38145933
Web of Science KeyUT 001164631200004
JaLCDOI 10.18926/AMO/66149
FullText URL 77_6_577.pdf
Author Liu, Siyu| Athurupana, Rukmali| Han, Hongmei| Yang, Titi| Nakatsuka, Mikiya|
Abstract Bereavement care is conducted to meet the emotional needs of grieving couples who are devastated by the experience of a miscarriage or stillbirth. From January to April 2022, we distributed a questionnaire that assessed the knowledge and attitudes of Japanese nursing staff (nurses and midwives) in Japan’s Chugoku-Shikoku region toward bereavement care for couples with miscarriage/stillbirth. The 370 survey respondents’ answers revealed that the nursing staff’s knowledge regarding recurrent pregnancy loss and subsequent bereavement care was insufficient. About 41.1% and 64.1% of the respondents had received school and on-the-job education in bereavement care, respectively, and 79.2% expressed willingness to provide such care. Our analyses revealed that the following factors were associated with the nursing staff’s knowledge level: parent status, age, reproductive history, midwifery license, work experience and environment, and on-the-job education. The following were correlated with the staff’s willingness to provide bereavement care: work environment, midwifery license, bereavement care knowledge, and on-the-job education. Together our findings indicate that education plays a significant role in equipping caregivers to provide effective bereavement care for couples who have experienced a miscarriage or stillbirth.
Keywords midwife nurse miscarriage bereavement knowledge
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-12
Volume volume77
Issue issue6
Publisher Okayama University Medical School
Start Page 577
End Page 587
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38145931
Web of Science KeyUT 001164631200002
JaLCDOI 10.18926/AMO/66148
FullText URL 77_6_567.pdf
Author Matsumoto, Naomi| Higuchi, Chigusa| Miyaji, Chikara| Mitsuhashi, Toshiharu| Hagiya, Hideharu| Takao, Soshi| Yorifuji, Takashi|
Abstract This paper presents the results of a series of surveys conducted from July 2021 to March 2023 to investigate the post-vaccination adverse reactions to the mRNA-1273 (Moderna) vaccine among faculty, staff, and students at Okayama University. These studies complement the official surveys conducted by the Ministry of Health, Labour and Welfare (MHLW) and provide a more representative picture of adverse reactions in the general population including large numbers of healthy young people. Pain, swelling, redness at the injection site, fever, headache, and malaise were the main adverse reactions reported. The proportion of adverse reactions was generally higher after the second vaccination and decreased with each additional vaccination. No statistically significant differences in the adverse reactions were found for males and females and those with/without a history of allergy, but a lower proportion of fever was observed in older participants and those with underlying medical conditions. We also evaluated the association between adverse reactions and antibody titers after the third vaccination and found no significant differences in antibody levels one month after vaccination. This series of studies highlights the importance of conducting surveys in diverse populations to provide a more representative picture of post-vaccination adverse reactions during a pandemic.
Keywords coronavirus disease 2019 adverse reactions mRNA vaccine antibody titers young adults
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2023-12
Volume volume77
Issue issue6
Publisher Okayama University Medical School
Start Page 567
End Page 575
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38145930
Web of Science KeyUT 001164631200001
FullText URL fulltext.pdf
Author Yoshimura, M.|
Published Date 2022-05-17
Publication Title Physical Review D
Volume volume105
Issue issue10
Publisher American Physical Society (APS)
Start Page 103522
ISSN 2470-0010
NCID AA00773624
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders ©2023 American Physical Society.
File Version publisher
DOI 10.1103/physrevd.105.103522
Web of Science KeyUT 000811638000014
Related Url isVersionOf https://doi.org/10.1103/physrevd.105.103522
FullText URL fulltext.pdf
Author Murakami, Taku| Yamamoto, Akira| Hagiya, Hideharu| Obika, Mikako| Mandai, Yasuhiro| Miyoshi, Tomoko| Kataoka, Hitomi| Otsuka, Fumio|
Keywords Medical Education Educational Measurement Simulation Training Peer Group Emergency Medicine Internship and residency Curriculum Personal satisfaction Case-control studies
Note The version of record of this article, first published in BMC Medical Education, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12909-023-04798-w|
Published Date 2023-11-12
Publication Title BMC Medical Education
Volume volume23
Issue issue1
Publisher BMC
Start Page 859
ISSN 1472-6920
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023.
File Version publisher
PubMed ID 37953233
DOI 10.1186/s12909-023-04798-w
Web of Science KeyUT 001103563600006
Related Url isVersionOf https://doi.org/10.1186/s12909-023-04798-w
FullText URL fulltext.pdf
Author Ichihara, Eiki| Hasegawa, Kou| Kudo, Kenichiro| Tanimoto, Yasushi| Nouso, Kazuhiro| Oda, Naohiro| Mitsumune, Sho| Yamada, Haruto| Takata, Ichiro| Hagiya, Hideharu| Mitsuhashi, Toshiharu| Taniguchi, Akihiko| Toyooka, Shinichi| Tsukahara, Kohei| Aokage, Toshiyuki| Tsukahara, Hirokazu| Kiura, Katsuyuki| Maeda, Yoshinobu|
Published Date 2023-10-26
Publication Title PLoS ONE
Volume volume18
Issue issue10
Publisher Public Library of Science
Start Page e0287501
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 Ichihara et al.
File Version publisher
PubMed ID 37883347
DOI 10.1371/journal.pone.0287501
Web of Science KeyUT 001094123400028
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0287501
FullText URL K0006901_abstract_review.pdf K0006901_fulltext.pdf K0006901_summary.pdf
Author INABA, Mototaka|
Published Date 2023-09-25
Content Type Thesis or Dissertation
Grant Number 甲第6901号
Granted Date 2023-09-25
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders © The Author(s) 2023
FullText URL fulltext20231112-02.pdf
Author Fujiwara, Masazumi|
Note This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Masazumi Fujiwara; Diamond quantum sensors in microfluidics technology. Biomicrofluidics 1 September 2023; 17 (5): 054107. https://doi.org/10.1063/5.0172795 and may be found at https://doi.org/10.1063/5.0172795.|
Published Date 2023-10-16
Publication Title Biomicrofluidics
Volume volume17
Issue issue5
Publisher AIP Publishing
Start Page 054107
ISSN 1932-1058
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 Author(s).
File Version author
PubMed ID 37854889
DOI 10.1063/5.0172795
Web of Science KeyUT 001086923400001
Related Url isVersionOf https://doi.org/10.1063/5.0172795
FullText URL fulltext.pdf
Author Yumoto, Tetsuya| Hongo, Takashi| Koide, Yasuhiro| Obara, Takafumi| Tsukahara, Kohei| Naito, Hiromichi| Nakao, Atsunori|
Keywords Emergency service Informed consent Radiation Treatment refusal
Note The version of record of this article, first published in BMC Medical Ethics, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12910-023-00962-5|
Published Date 2023-10-04
Publication Title BMC Medical Ethics
Volume volume24
Issue issue1
Publisher BMC
Start Page 80
ISSN 1472-6939
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023.
File Version publisher
PubMed ID 37794408
DOI 10.1186/s12910-023-00962-5
Web of Science KeyUT 001080177500004
Related Url isVersionOf https://doi.org/10.1186/s12910-023-00962-5
JaLCDOI 10.18926/AMO/65975
FullText URL 77_5_527.pdf
Author Ando, Miho| Hanayama, Yoshihisa| Nishimura, Yoshito| Hagiya, Hideharu| Otsuka, Fumio|
Abstract Retroperitoneal fibrosis (RPF) is a rare cause of hydronephrosis and progressive renal dysfunction with unidentified origin. RPF is categorized into idiopathic RPF with/without immunoglobulin G4 (IgG4)-related disease (IgG4-RD), and secondary RPF. Identifying the underlying cause is challenging and often associated with delayed diagnosis or therapeutic interventions. We investigated RPF’s clinical characteristics based on different etiologies and factors that may help distinguish the underlying causes. We analyzed the cases of 49 patients with RPF that was radiographically diagnosed at our institution (2008-2022). The cohort was 77.6% males; 75.5% had idiopathic RPF and 24.5% had secondary RPF. Among the idiopathic patients, 54.1% had IgG4-RD. The patients were likely to have abdominal pain, lower back pain/lumbago, and constitutional symptoms including generalized fatigue and fever. The idiopathic patients were likely to have higher serum IgG4 and IgG levels and lower serum C3 levels compared to secondary RPF. The IgG4-RPF patients were likely to have higher serum IgG4 levels and lower serum C-reactive protein, ferritin, and C3 levels compared to the idiopathic RPF patients without IgG4-RD. These findings might reflect underlying systemic inflammatory responses. Comprehensive laboratory testing, including serum inflammatory markers and immunological panels, is recommended for radiologically diagnosed RPF patients.
Keywords retroperitoneal fibrosis IgG4-related disease malignancy
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 527
End Page 536
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899264
Web of Science KeyUT 001108661600010
JaLCDOI 10.18926/AMO/65973
FullText URL 77_5_511.pdf
Author Sato, Kohei| Tsuji, Hironori| Yorimitsu, Masanori| Uehara, Takenori| Okazaki, Yuki| Takao, Shinichiro| Hata, Toshiaki| Fukuoka, Shiro| Noda, Tomoyuki| Kanda, Hideyuki| Ozaki, Toshifumi|
Abstract Sarcopenia and malnutrition are increasing in older adults and are reported risk factors for functional impairment after hip fracture surgery. This study aimed to investigate the associations between skeletal muscle mass loss, malnutrition, and postoperative walking ability in patients with hip fracture. We retrospectively reviewed patients who underwent intertrochanteric fracture surgery at our institute. The psoas muscle index, controlling nutritional status score, and functional ambulation category (FAC) were used to evaluate skeletal muscle mass, nutritional status, and walking ability, respectively. Six months after surgery, walking ability was assessed as either “gait disturbance” or “independent gait”. Multivariate binomial logistic regression analysis, with skeletal muscle mass, nutritional status, and other factors, was used to predict the risk of being assigned to the gait disturbance group. This study included 95 patients (mean age, 85.2 years; 70 women). Sixty-six patients had low skeletal muscle mass, 35 suffered from malnutrition, and 28 had both. Malnutrition and low skeletal muscle mass were significantly associated with postoperative gait disturbance (FAC < 3). Preoperative low skeletal muscle mass and malnutrition were risk factors for postoperative poor walking ability. Further preventive interventions focusing on skeletal muscle mass and nutritional status are required.
Keywords sarcopenia nutrition geriatric hip fracture psoas muscle index controlling nutritional status score
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 511
End Page 516
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899262
Web of Science KeyUT 001108661600008
FullText URL fulltext.pdf
Author Akıl, Caner| Ali, Samson| Tran, Linh T.| Gaillard, Jérémie| Li, Wenfei| Hayashida, Kenichi| Hirose, Mika| Kato, Takayuki| Oshima, Atsunori| Fujishima, Kosuke| Blanchoin, Laurent| Narita, Akihiro| Robinson, Robert C.|
Published Date 2022-03-25
Publication Title Science Advances
Volume volume8
Issue issue12
Publisher American Association for the Advancement of Science (AAAS)
Start Page eabm2225
ISSN 2375-2548
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Authors
File Version publisher
PubMed ID 35333570
DOI 10.1126/sciadv.abm2225
Web of Science KeyUT 000800334900012
Related Url isVersionOf https://doi.org/10.1126/sciadv.abm2225
FullText URL fulltext.pdf
Author Hiraoka, Tomohiro| Kawamura, Mai| Takada, Keisuke| Moriwake, Tadashi|
Keywords Cystinuria Ureterolithiasis Cystine Acute appendicitis Case report
Published Date 2022-10
Publication Title International Journal of Surgery Case Reports
Volume volume99
Publisher Elsevier
Start Page 107596
ISSN 2210-2612
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Authors.
File Version publisher
PubMed ID 36115118
DOI 10.1016/j.ijscr.2022.107596
Web of Science KeyUT 001043865800003
Related Url isVersionOf https://doi.org/10.1016/j.ijscr.2022.107596
Title Alternative A third step of visual art instruction in medical education : Introduction of visual thinking strategies supported by Okayama Prefectural Museum of Art
Author Kimata, Yoshihiro| Obika, Mikako| Kubo, Takuya| Otsuka, Masumi| Okamoto, Yuko| Fukutomi, Koh| Matsumoto, Hiroshi|
Publication Title Journal of Okayama Medical Association
Published Date 2023-08-01
Volume volume135
Issue issue2
Start Page 85
End Page 88
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.135.85
language Japanese
Copyright Holders Copyright (c) 2023 岡山医学会
File Version publisher
DOI 10.4044/joma.135.85
FullText URL K003052.pdf
Author Nobuhisa, Tetsuji|
Published Date 2005-12-31
Content Type Thesis or Dissertation
Grant Number 甲第3052号
Granted Date 2005-12-31
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
FullText URL fulltext.pdf
Author Cong, Yingnan| Hou, Yufei| Jiang, Jiaming| Chen, Shuangzi| Cai, Xiaojing|
Keywords energy trade complex networks topology evolutionary properties
Published Date 2023-07-28
Publication Title Energies
Volume volume16
Issue issue15
Publisher MDPI
Start Page 5677
ISSN 1996-1073
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
DOI 10.3390/en16155677
Web of Science KeyUT 001045434700001
Related Url isVersionOf https://doi.org/10.3390/en16155677
FullText URL fulltext.pdf
Author Liu, Ziang| Nishi, Tatsushi|
Keywords Evolutionary algorithm Inventory management Data-driven Supply chain Digital twin
Note The version of record of this article, first published in Complex & Intelligent Systems, is available online at Publisher’s website: http://dx.doi.org/10.1007/s40747-023-01179-0|
Published Date 2023-08-09
Publication Title Complex & Intelligent Systems
Volume volume10
Issue issue1
Publisher Springer
Start Page 825
End Page 846
ISSN 2199-4536
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023
File Version publisher
DOI 10.1007/s40747-023-01179-0
Web of Science KeyUT 001044871100001
Related Url isVersionOf https://doi.org/10.1007/s40747-023-01179-0
JaLCDOI 10.18926/AMO/65755
FullText URL 77_4_429.pdf
Author Sasanami, Misa| Iida, Atsuyoshi| Iwamuro, Masaya| Hirai, Ryousuke| Obara, Takashi| Tsukahara, Kohei| Yumoto, Tetsuya| Naito, Hiromichi| Nakao, Atsunori|
Abstract Intramural esophageal dissection (IED), characterized by bleeding into the submucosal space, leads to mucosal separation and dissection. The most prevalent symptoms are sudden chest or retrosternal pain, hematemesis, and dysphagia. Therefore, acute coronary syndrome and aortic dissection are among its most notable differential diagnoses. A 31-year-old pregnant woman presented with acute chest pain, laryngeal discomfort, and hematemesis. Emergency esophagogastroscopy revealed longitudinal mucosal dissection (upper esophagus to esophagogastric junction). The patient was successfully treated by avoiding the ingestion of solid foods. Clinicians should consider a diagnosis of IED for pregnant patients with acute chest pain, especially if hematemesis is present.
Keywords chest pain dysphagia esophageal dissection hematemesis
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-08
Volume volume77
Issue issue4
Publisher Okayama University Medical School
Start Page 429
End Page 431
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37635144
Web of Science KeyUT 001163659800012
JaLCDOI 10.18926/AMO/65753
FullText URL 77_4_423.pdf
Author Yamakawa, Yasuaki| Miyashita, Kohei| Morizane, Atsushi| Takeuchi, Masato| Kawashima, Yuta| Sugimura, Tomoko| Saisaka, Yuichi|
Abstract We report a case of a patient with severe pelvic fracture who showed concurrent ST elevation on electrocardiogram. A 70-year-old man incurred an unstable pelvic fracture from a motorcycle accident. On admission, he was hemodynamically unstable, and massive transfusion and noradrenaline were administered immediately. Although ST elevation was present in leads II, III, aVF, V5, and V6, cardiac function was preserved; thus, trans-arterial embolization and external fixation for pelvic fracture were given priority. Four days after the injury, he suffered a cardiac arrest, and coronary angiography revealed that the cause of ST elevation and cardiac arrest was coronary vasospasm. Physicians should be aware that pain-related stress and platelet activation as well as use of noradrenaline in severe trauma cases can induce coronary vasospasm.
Keywords coronary spasm angina noradrenaline severe trauma ST elevation treatment strategy
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-08
Volume volume77
Issue issue4
Publisher Okayama University Medical School
Start Page 423
End Page 427
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37635143
Web of Science KeyUT 001163659800004
JaLCDOI 10.18926/AMO/65751
FullText URL 77_4_407.pdf
Author Hotta, Kensuke| Kobayashi, Takaomi|
Abstract This study aimed to investigate the usefulness of force-controlled pelvic stress radiographs in the evaluation and treatment of fragility fractures of the pelvis (FFP) using a functional treatment strategy. We conducted a retrospective study of 55 geriatric patients with FFP who underwent pelvic stress radiographs on admission. The differences in the sacral width, pelvic ring width, and medial femoral head width between the radiographs with and without the Sam Sling II M size were defined as Δ sacral width, Δ pelvic ring width, and Δ medial femoral head width, respectively. We used Pearson’s correlation test to assess the relationship between the degree of radiographic instability and the Johns Hopkins highest level of mobility scale (JH-HLM) at 10-days postadmission. Conventional receiver-operating-characteristic curve analysis was used to identify cases requiring surgery using the best cutoff value for radiographic instability. The JH-HLM was significantly correlated with Δ sacral width (r=−0.401, p=0.017), but not with Δ pelvic ring width (r=−0.298, p=0.080) nor with Δ medial femoral head width (r= −0.261, p=0.128). The best cutoff value of Δ sacral width in identifying surgical cases was 10.7 mm (sensitivity 75.0%, specificity 98.0%). Force-controlled pelvic stress radiographs could be helpful in assessing the need for surgery on admission.
Keywords fragility fracture of the pelvis functional treatment strategy Sam Sling stress radiograph Johns Hopkins highest level of mobility scale
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-08
Volume volume77
Issue issue4
Publisher Okayama University Medical School
Start Page 407
End Page 414
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37635141
Web of Science KeyUT 001163659800001