result 546 件
| FullText URL | fulltext.pdf |
|---|---|
| Author | Hiraoka, Tomohiro| Obara, Takafumi| Matsumoto, Naomi| Tsukahara, Kohei| Hongo, Takashi| Nojima, Tsuyoshi| Hisamura, Masaki| Yumoto, Tetsuya| Nakao, Atsunori| Yorifuji, Takashi| Naito, Hiromichi| |
| Keywords | Retrospective cohort study Injury recurrence Injury prevention |
| Note | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-76403-z| |
| Published Date | 2024-10-21 |
| Publication Title | Scientific Reports |
| Volume | volume14 |
| Issue | issue1 |
| Publisher | Nature Portfolio |
| Start Page | 24716 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2024 |
| File Version | publisher |
| PubMed ID | 39433855 |
| DOI | 10.1038/s41598-024-76403-z |
| Web of Science KeyUT | 001339991400047 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-024-76403-z |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsuo, Toshihiko| Iwamoto, Yoshitaka| Okamoto, Hironori| Iguchi, Daisuke| |
| Keywords | infective endocarditis maxillary sinusitis ocular proptosis orbital vascular malformation streptococcus anginosus |
| Published Date | 2024-11-30 |
| Publication Title | Cureus |
| Volume | volume16 |
| Issue | issue11 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | e74873 |
| ISSN | 2168-8184 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Copyright 2024 Matsuo et al. |
| File Version | publisher |
| DOI | 10.7759/cureus.74873 |
| Related Url | isVersionOf https://doi.org/10.7759/cureus.74873 |
| JaLCDOI | 10.18926/OER/67707 |
|---|---|
| Title Alternative | Reproducing Self-organizing Agglomeration using Agent-based Model: ICT Establishments in Tokyo’s Special Wards |
| FullText URL | oer_056_2_041_071.pdf |
| Author | Nakamura, Ryohei| Nagamune, Takeshi| Hayashi, Syusei| |
| Abstract | As a preliminary step to conducting a self-organizing simulation of the agglomeration and dispersion of the information and communications industry, we quantify the spatial agglomeration of the information and communications industry in Japan’s major cities. Using the town and district data from the Economic Census for Economic Activity, we attempted a spatial analysis of the information and communications industry in the Tokyo Special Wards as well as in Sapporo, Sendai, Hiroshima, and Fukuoka, which have regional central functions. As a result of detecting spatial autocorrelation in small areas within each city, hotspots indicating the agglomeration of information and communications industry offi ces were found in the city center of each city. At the same time, we were able to confi rm the impact of agglomeration economies, which are the premise of the self-organizing model, and confi rmed that the information and communications industry is an industry suitable for simulation of the self-organizing model. Krugman（1996）was the fi rst to model the self-organizing model in cities and clarifi ed the emergence principle of peripheral cities, but this was limited to numerical simulations. Later, Kumar et al.（2007）used actual data to show that Krugman’s self-organizing model could be applied to predict corporate agglomeration and dispersion. In this paper, we use an agent-based model to examine whether a self-organizing model is also effective in reproducing and predicting the concentration and dispersion of the information and communications industry in Japanese cities. |
| Publication Title | Okayama Economic Review |
| Published Date | 2024-11-25 |
| Volume | volume56 |
| Issue | issue2 |
| Start Page | 41 |
| End Page | 71 |
| ISSN | 2433-4146 |
| language | Japanese |
| Copyright Holders | Copyright © 2024 岡山大学経済学会 |
| File Version | publisher |
| JaLCDOI | 10.18926/AMO/67667 |
|---|---|
| FullText URL | 78_5_423.pdf |
| Author | Sakamoto, Shinya| Tabuchi, Motoyasu| Yoshimatsu, Rika| Hishida, Ai| Matsumoto, Manabu| Iwata, Jun| Okabayashi, Takehiro| |
| Abstract | Nesidioblastosis, also known as persistent hyperinsulinemic hypoglycemia, is usually observed in children and infants, although more recently adult-onset nesidioblastosis has also been described. We present a case of nesidioblastosis in a 78-year-old man that was detected by 111In-pentetreotide single photon emission computed tomography (SPECT/CT). The patient was transferred to our hospital’s emergency department in a hypoglycemic coma. Dynamic enhanced CT could detect no lesion in the pancreas, but an 111In-pentetreotide SPECT/CT scan performed after a similar episode four weeks later showed increased focal uptake at the head of the pancreas. The results of a selective arterial calcium injection test were negative. After careful consideration and discussion among colleagues, surgical intervention was selected, and a pancreaticoduodenectomy was performed. On histology, there were elevated numbers of Langerhans islets in the pancreatic head, and the islets themselves appeared enlarged. Hypertrophic β-cells comprised the majority, but α-cells, δ-cells and pancreatic polypeptide were also detected in the islets. Based on the histopathological results and repeated hyperinsulinemic hypoglycemic crises, the patient was finally diagnosed with adult-onset nesidioblastosis. He had no hypoglycemic symptoms during outpatient follow-up examination. Since 111In-pentetreotide SPECT/CT may be able to detect nesidioblastosis, clinicians should consider this relatively new-modality examination when encountering such cases. |
| Keywords | 111In-pentetreotide nesidioblastosis single-photon emission computed tomography hyperinsulinemic hypoglycemia |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-10 |
| Volume | volume78 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 423 |
| End Page | 428 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 39467661 |
| Web of Science KeyUT | 001343346400009 |
| JaLCDOI | 10.18926/AMO/67664 |
|---|---|
| FullText URL | 78_5_401.pdf |
| Author | Toyota, Yusuke| Uda, Kazuhiro| Shirabe, Komei| Moriwake, Tadashi| |
| Abstract | Severe febrile thrombocytopenia syndrome (SFTS) is a tick-borne infectious disease that is endemic in parts of eastern Asia. Few pediatric cases have been reported. We describe a case of SFTS in a seven-year-old girl who presented with prolonged fever and gastrointestinal symptoms. Leukopenia and thrombocytopenia on hematology, and a history of outdoor activity led us to diagnose SFTS, although the patient had no tick bite marks. We also review the literature and discuss the characteristics of pediatric SFTS. Physicians should consider SFTS in the differential diagnosis of fever with thrombocytopenia in children living in endemic areas. |
| Keywords | child tick-borne disease severe febrile thrombocytopenia syndrome zoonoses |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-10 |
| Volume | volume78 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 401 |
| End Page | 405 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 39467658 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Mitoma, Tomohiro| Maki, Jota| Ooba, Hikaru| Masuyama, Hisashi| |
| Published Date | 2024-10-08 |
| Publication Title | BMJ Open |
| Volume | volume14 |
| Issue | issue10 |
| Publisher | BMJ Publishing Group |
| Start Page | e087657 |
| ISSN | 2044-6055 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Author(s) (or their employer(s)) 2024. |
| File Version | publisher |
| PubMed ID | 39384228 |
| DOI | 10.1136/bmjopen-2024-087657 |
| Web of Science KeyUT | 001329970500001 |
| Related Url | isVersionOf https://doi.org/10.1136/bmjopen-2024-087657 |
| JaLCDOI | 10.18926/AMO/67657 |
|---|---|
| FullText URL | 78_5_371.pdf |
| Author | Gotoh, Kazuyoshi| Miyoshi, Makoto| I Putu Bayu Mayura| Tsuji, Shuma| Iio, Koji| Fukushima, Shinnosuke| Matsushita, Osamu| Hagiya, Hideharu| |
| Abstract | Spread of carbapenemase-producing Enterobacterales (CPE) is an ongoing public health issue worldwide, including in Japan. In this study, we investigated the phenotypic and genetic characteristics of CPE isolates at Okayama University Hospital over the 5 years (2013-2018) prior to the outbreak of the 2019 coronavirus pandemic. Of 24 carbapenem-resistant Enterobacterales isolated during the study period, we identified 8 CPE isolates harboring blaIMP-1 (5 isolates) and blaIMP-6 genes (3 isolates). Bacterial species and carbapenem susceptibility patterns exhibited diversity. Minimum inhibitory concentrations (MICs) of meropenem were generally higher than those of imipenem and biapenem. Results of pulsed-field gel electrophoresis demonstrated that neither clonal nor plasmid-mediated outbreaks of blaIMP-harboring CPE isolates have developed at our hospital. One Klebsiella oxytoca isolate showed a high MIC (128 μg/mL) of meropenem, which could be explained by the high plasmid copy number. Subsequent analysis of this isolate may elucidate the intricacies of carbapenem resistance profiles among CPE isolates. Collectively, our findings underscore the necessity for ongoing genetic surveillance of CPE, complemented by tailored approaches for infection prevention and control. |
| Keywords | antimicrobial resistance carbapenemase-producing enterobacterales carbapenemase-resistant enterobacterales Silent pandemic whole genome sequence |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-10 |
| Volume | volume78 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 371 |
| End Page | 376 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 39467655 |
| Web of Science KeyUT | 001343346400003 |
| JaLCDOI | 10.18926/AMO/67656 |
|---|---|
| FullText URL | 78_5_363.pdf |
| Author | Takanaga, Satoe| Matsumoto, Naomi| Kadowaki, Tomoka| Takao, Soshi| Yorifuji, Takashi| |
| Abstract | Kawasaki disease (KD) is a pediatric disease of unknown etiology that commonly affects infants in East Asia. Infants born small for gestational age (SGA) have weaker immune systems and are more susceptible to infection. Using data from a nationwide Japanese birth cohort study conducted in 2010 (n=34,579), we investigated whether SGA increases the risk of KD. SGA was defined as birth weight below the 10th percentile for gestational age. The outcome was hospitalization for KD between 6 and 30 months of age. The association between SGA and hospitalization for KD, adjusted for child and maternal factors, was examined using logistic regression. Of the 231 children hospitalized for KD, 9.5% were SGA. Further statistical analysis showed that SGA did not increase the odds ratio (OR) of hospitalization for KD (adjusted OR 1.12, 95% confidence interval 0.71-1.75). This result was not changed with stratification by early daycare attendance and preterm status. Reasons for the lack of association may include the multifactorial pathogenesis of KD; in addition, the types of infections to which SGA infants are predisposed may differ from those triggering KD. Overall, our large nationwide study found no association between SGA and KD. |
| Keywords | Kawasaki disease (KD) small for gestational age (SGA) cohort epidemiology |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-10 |
| Volume | volume78 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 363 |
| End Page | 370 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 39467654 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Bekku, Kensuke| Kawada, Tatsushi| Yanagisawa, Takafumi| Karakiewicz, Pierre I.| Shariat, Shahrokh F.| |
| Keywords | lymph node dissection lymph node metastasis lymphadenectomy lymphadenopathy Renal cell carcinoma |
| Published Date | 2023-07 |
| Publication Title | Current Opinion in Urology |
| Volume | volume33 |
| Issue | issue4 |
| Publisher | Ovid Technologies (Wolters Kluwer Health) |
| Start Page | 294 |
| End Page | 301 |
| ISSN | 0963-0643 |
| NCID | AA10867655 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 The Author(s). |
| File Version | publisher |
| PubMed ID | 37014778 |
| DOI | 10.1097/mou.0000000000001095 |
| Web of Science KeyUT | 001002602200008 |
| Related Url | isVersionOf https://doi.org/10.1097/mou.0000000000001095 |
| Title Alternative | The 2023 Incentive Award of the Okayama Medical Association in General Medical Science (2023 Yuuki Prize) |
|---|---|
| Author | Naito, Hiromichi| |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2024-08-01 |
| Volume | volume136 |
| Issue | issue2 |
| Start Page | 48 |
| End Page | 50 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.136.48 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2024 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.136.48 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Fukao, Takashi| Fujiwara, Masaki| Yamada, Yuto| Sakamoto, Shinji| Matsumoto, Yosuke| Takaki, Manabu| |
| Keywords | anti-seizure medications attention-deficit/hyperactivity disorder electroencephalography transient epileptic amnesia |
| Published Date | 2024-08-22 |
| Publication Title | Psychiatry and Clinical Neurosciences Reports |
| Volume | volume3 |
| Issue | issue3 |
| Publisher | Wiley |
| Start Page | e70003 |
| ISSN | 2769-2558 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 The authors. |
| File Version | publisher |
| PubMed ID | 39184058 |
| DOI | 10.1002/pcn5.70003 |
| Web of Science KeyUT | 001295703300001 |
| Related Url | isVersionOf https://doi.org/10.1002/pcn5.70003 |
| FullText URL | fulltext20240820-02.pdf fig20240820-02.pdf table20240820-02.pdf suppl_fig20240820-02.pdf suppl_table20240820-02.pdf |
|---|---|
| Author | Matsumoto, Naomi| Sasaki, Ayako| Kadowaki, Tomoka| Mitsuhashi, Toshiharu| Takao, Soshi| Yorifuji, Takashi| |
| Keywords | SARS-CoV-2 Vaccine Antibody Mixed-effects model Omicron |
| Note | © 2024 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Aug. 2025.| |
| Published Date | 2024-08 |
| Publication Title | Vaccine |
| Volume | volume42 |
| Issue | issue21 |
| Publisher | Elsevier BV |
| Start Page | 126156 |
| ISSN | 0264-410X |
| NCID | AA10491877 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 Elsevier Ltd. |
| File Version | author |
| PubMed ID | 39088986 |
| DOI | 10.1016/j.vaccine.2024.126156 |
| Web of Science KeyUT | 001285745600001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.vaccine.2024.126156 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yumoto, Tetsuya| Hongo, Takashi| Obara, Takafumi| Ageta, Kohei| Aokage, Toshiyuki| Tsukahara, Kohei| Nakao, Atsunori| Naito, Hiromichi| |
| Keywords | clinical conference end-of-life care ICU rounds multidisciplinary team meetings |
| Published Date | 2024-07-24 |
| Publication Title | Journal of Clinical Medicine |
| Volume | volume13 |
| Issue | issue15 |
| Publisher | MDPI |
| Start Page | 4324 |
| ISSN | 2077-0383 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 by the authors. |
| File Version | publisher |
| PubMed ID | 39124591 |
| DOI | 10.3390/jcm13154324 |
| Web of Science KeyUT | 001287177900001 |
| Related Url | isVersionOf https://doi.org/10.3390/jcm13154324 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tsuge, Mitsuru| Ichihara, Eiki| Hasegawa, Kou| Kudo, Kenichiro| Tanimoto, Yasushi| Nouso, Kazuhiro| Oda, Naohiro| Mitsumune, Sho| Kimura, Goro| Yamada, Haruto| Takata, Ichiro| Mitsuhashi, Toshiharu| Taniguchi, Akihiko| Tsukahara, Kohei| Aokage, Toshiyuki| Hagiya, Hideharu| Toyooka, Shinichi| Tsukahara, Hirokazu| Maeda, Yoshinobu| |
| Keywords | novel coronavirus disease 2019 pneumonia hydroperoxide nitric oxide reactive oxygen species citrulline arginine asymmetric dimethylarginine |
| Published Date | 2024-07-31 |
| Publication Title | International Journal of Molecular Sciences |
| Volume | volume25 |
| Issue | issue15 |
| Publisher | MDPI |
| Start Page | 8370 |
| ISSN | 1661-6596 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 by the authors. |
| File Version | publisher |
| PubMed ID | 39125944 |
| DOI | 10.3390/ijms25158370 |
| Web of Science KeyUT | 001286890700001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms25158370 |
| JaLCDOI | 10.18926/AMO/67203 |
|---|---|
| FullText URL | 78_3_281.pdf |
| Author | Okada, Kazuhiro| Maki, Yuho| Matsubara, Kei| Hirano, Yutaka| Fujiwara, Toshiya| Matsuura, Motoki| |
| Abstract | A 24-year-old Japanese female with anorexia nervosa presented to our hospital for bilateral pneumothorax, and 12-Fr thoracostomy catheters were inserted into the bilateral pleural cavities. On hospital day 9, a thoracoscopic bullectomy was performed. However, air leakage relapsed on both sides on postoperative day 1. The air leakage on the right side was particularly persistent, and we switched the drainage to a Heimlich valve. Both lungs expanded gradually and the chest tube was removed on postoperative day 19. Passive pleural drainage might be an option for prolonged air leakage after a bullectomy in patients with anorexia nervosa. |
| Keywords | spontaneous pneumothorax anorexia nervosa Heimlich valve |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-06 |
| Volume | volume78 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 281 |
| End Page | 284 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 38902216 |
| Web of Science KeyUT | 001267351900001 |
| JaLCDOI | 10.18926/AMO/67201 |
|---|---|
| FullText URL | 78_3_259.pdf |
| Author | Vural, Gonul| Demir, Esra| Gumusyayla, Sadiye| Eren, Funda| Barakli, Serdar| Neselioglu, Salim| Erel, Ozcan| |
| Abstract | The aim of this study is to investigate the relationship of the lipid profile, dysfunctional high-density lipoprotein, ischaemia-modified albumin and thiol–disulfide homeostasis with cognitive impairment, fatigue and sleep disorders in patients with multiple sclerosis. The cognitive functions of patients were evaluated with the Brief International Cognitive Assessment for Multiple Sclerosis battery. Fatigue was evaluated with the Fatigue Severity Scale and the Fatigue Impact Scale. The Pittsburgh Sleep Quality Index and the Epworth Sleepiness Scale were used to assess patients’ sleep disturbance. Peripheral blood samples were collected, and lipid levels and myeloperoxidase and paraoxonase activity were measured. The myeloperoxidase/paraoxonase ratio, which indicates dysfunctional high-density lipoprotein, was calculated. Thiol–disulfide homeostasis and ischaemia-modified albumin were measured. We did not identify any relationship between dysfunctional high-density lipoprotein and the physical disability, cognitive decline, fatigue and sleep problems of multiple sclerosis. Thiol–disulfide homeostasis was associated with cognitive scores. The shift of the balance towards disulfide was accompanied by a decrease in cognitive scores. On the other hand, we did not detect any relationship between fatigue and sleep disorders and thiol–disulfide homeostasis. Our findings revealed a possible correlation between cognitive dysfunction and thiol–disulfide homeostasis in multiple sclerosis patients. |
| Keywords | multiple sclerosis dysfunctional HDL thiol–disulfide homeostasis cognitive decline |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-06 |
| Volume | volume78 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 259 |
| End Page | 270 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 38902214 |
| Web of Science KeyUT | 001267351000007 |
| JaLCDOI | 10.18926/AMO/67197 |
|---|---|
| FullText URL | 78_3_227.pdf |
| Author | Wada, Yudai| Ushio, Soichiro| Kitamura, Yoshihisa| Zamami, Yoshito| Sendo, Toshiaki| |
| Abstract | Zolpidem, a non-benzodiazepine hypnotic, is primarily used to treat insomnia. In a previous study, pior treatment with non-benzodiazepine receptor agonists was associated with inflammation. The present study aimed to clarify the association between the effects of zolpidem and inflammation in mice treated with lipopolysaccharide (LPS), a known model of inflammation. We assessed the zolpidem-induced loss of righting reflex (LORR) duration 24 h after LPS treatment in mice. Additionally, the expressions of γ-aminobutyric acid (GABA)A receptor subunit and K+-Cl− cotransporter isoform 2 (KCC2) mRNA in the hippocampus and frontal cortex were examined in LPS-treated mice. Pretreatment with LPS was associated with significantly prolonged duration of zolpidem-induced LORR compared to control mice. This effect was significantly attenuated by administering bicuculline, a GABAA receptor antagonist, or flumazenil, a benzodiazepine receptor antagonist, in LPS-treated mice. Compared to controls, LPS-treated mice showed no significant change in the expression of GABAA receptor subunits in the hippocampus or frontal cortex. Bumetanide, an Na+-K+-2Cl− cotransporter isoform 1 blocker, attenuated the extended duration of zolpidem-induced LORR observed in LPS-treated mice. LPS significantly decreased Kcc2 mRNA expression in the hippocampus and the frontal cortex. These findings suggest that inflammation increases zolpidem-induced LORR, possibly through a reduction in KCC2 expression. |
| Keywords | lipopolysaccharide zolpidem GABAA receptor K+-Cl− cotransporters |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-06 |
| Volume | volume78 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 227 |
| End Page | 235 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 38902210 |
| Web of Science KeyUT | 001267351000003 |
| JaLCDOI | 10.18926/AMO/67195 |
|---|---|
| FullText URL | 78_3_205.pdf |
| Author | Hagiya, Hideharu| |
| Abstract | The global pandemic of COVID-19 has underscored the significance of establishing and sustaining a practical and efficient infection control system for the benefit and welfare of society. Infectious disease (ID) specialists are expected to take on leadership roles in enhancing organizational infrastructures for infection prevention and control (IPC) at the hospital, community, and national levels. However, due to an absolute shortage and an uneven distribution, many core hospitals currently lack the ID specialists. Given the escalating global risk of emerging and re-emerging infectious diseases as well as antimicrobial resistance pathogens, the education and training of ID specialists constitutes an imperative concern. As demonstrated by historical changes in the healthcare reimbursement system, the establishment and enhancement of IPC measures is pivotal to ensuring medical safety. The existing structure of academic society-driven certification and training initiatives for ID specialists, contingent upon the discretionary decisions of individual physicians, possesses both quantitative and qualitative shortcomings. In this article, I first address the present situations and challenges related to ID specialists and then introduce my idea of securing ID specialists based on the new concepts and platforms; (i) ID Specialists as National Credentials, (ii) Establishment of the Department of Infectious Diseases in Medical and Graduate Schools, (iii) Endowed ID Educative Courses Funded by Local Government and Pharmaceutical Companies, and (iv) Recruitment of Young Physicians Engaged in Healthcare Services in Remote Areas. As clarified by the COVID-19 pandemic, ID specialists play a crucial role in safeguarding public health. Hopefully, this article will advance the discussion and organizational reform for the education and training of ID specialists. |
| Keywords | antimicrobial resistance emerging infectious diseases infection prevention and control medical education silent pandemic |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-06 |
| Volume | volume78 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 205 |
| End Page | 213 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 38902208 |
| Web of Science KeyUT | 001267351000001 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Vo, Quan Duy| Saito, Yukihiro| Ida, Toshihiro| Nakamura, Kazufumi| Yuasa, Shinsuke| |
| Published Date | 2024-05-21 |
| Publication Title | PLoS ONE |
| Volume | volume19 |
| Issue | issue5 |
| Publisher | Public Library of Science |
| Start Page | e0302537 |
| ISSN | 1932-6203 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 Vo et al. |
| File Version | publisher |
| PubMed ID | 38771829 |
| DOI | 10.1371/journal.pone.0302537 |
| Web of Science KeyUT | 001228816000059 |
| Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0302537 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Hirata, Yuichi| Takahashi, Yu| Kuramoto, Satoshi| Nishihiro, Shingo| Ono, Yasuhiro| Ichikawa, Tomotsugu| |
| Keywords | Acute epidural hematoma Middle meningeal artery embolization Transcatheter arterial embolization |
| Published Date | 2024-05 |
| Publication Title | International Journal of Surgery Case Reports |
| Volume | volume118 |
| Publisher | Elsevier |
| Start Page | 109704 |
| ISSN | 2210-2612 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 The Author(s). |
| File Version | publisher |
| PubMed ID | 38669807 |
| DOI | 10.1016/j.ijscr.2024.109704 |
| Web of Science KeyUT | 001235165400001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.ijscr.2024.109704 |
