result 852 件
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sasaki, Shigenori| Ogawa, Hirohito| Katoh, Hirokazu| Honda, Tomoyuki| |
| Keywords | antiviral antivirals Borna disease virus CRISPR/Cas13b persistent infection |
| Published Date | 2024-03-20 |
| Publication Title | International Journal of Molecular Sciences |
| Volume | volume25 |
| Issue | issue6 |
| Publisher | MDPI |
| Start Page | 3523 |
| ISSN | 1661-6596 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 by the authors. |
| File Version | publisher |
| PubMed ID | 38542493 |
| DOI | 10.3390/ijms25063523 |
| Web of Science KeyUT | 001192979100001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms25063523 |
| FullText URL | fulltext20240304-04.pdf |
|---|---|
| Author | Suzuki, Takehito| Murakami, Hironobu| Uchiyama, Jumpei| Sato, Reiichiro| Takemura-Uchiyama, Iyo| Ogata, Masaya| Sogawa, Kazuyuki| Ishida, Hiroho| Atipairin, Apichart| Matsushita, Osamu| Nagai, Makoto| |
| Keywords | Bovine leukemia virus Volatile fatty acids Rumen Gut, Microbiota Cows |
| Note | The version of record of this article, first published in Annals of Microbiology, is available online at Publisher’s website: http://dx.doi.org/10.1186/s13213-023-01737-4| |
| Published Date | 2023-09-16 |
| Publication Title | Annals of Microbiology |
| Volume | volume73 |
| Issue | issue1 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 31 |
| ISSN | 1869-2044 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023. |
| File Version | publisher |
| DOI | 10.1186/s13213-023-01737-4 |
| Web of Science KeyUT | 001166589200001 |
| Related Url | isVersionOf https://doi.org/10.1186/s13213-023-01737-4 |
| JaLCDOI | 10.18926/AMO/66676 |
|---|---|
| FullText URL | 78_1_089.pdf |
| Author | Toshima, Kei| Shien, Tadahiko| Nishimura, Midori Filiz| Suzuki, Yoko| Nakamoto, Shogo| Uno, Maya| Yoshioka, Ryo| Tsukioki, Takahiro| Takahashi, Yuko| Iwamoto, Takayuki| Iwatani, Tsuguo| Yanai, Hiroyuki| |
| Abstract | We report our experience with the diagnosis and treatment of an ectopic breast cancer arising within an axillary lymph node. The patient was a 65-year-old woman diagnosed breast cancer and axillary lymph node metastasis. We performed a partial mastectomy and axillary lymph node dissection. Postoperative pathology revealed no malignant lesions in the breast; however, a nodule in one of axillary lymph nodes had mixed benign and malignant components, leading to a diagnosis of invasive ductal carcinoma derived from ectopic mammary tissue. This case represents a very rare form of breast cancer, and the malignancy was difficult to distinguish from metastasis. |
| Keywords | breast cancer ectopic breast cancer axillary lymph node |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-02 |
| Volume | volume78 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 89 |
| End Page | 93 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 38419320 |
| Web of Science KeyUT | 001204421300001 |
| JaLCDOI | 10.18926/AMO/66668 |
|---|---|
| FullText URL | 78_1_029.pdf |
| Author | Kitayama, Takahiro| Tanaka, Takashi| Kanie, Yuichiro| Marukawa, Yohei| Kojima, Katsuhide| Tanaka, Takehiro| Takao, Soshi| Hiraki, Takao| |
| Abstract | This retrospective study investigated whether necrotic lesions detected on a computed tomography (CT) scan are more regressive than non-necrotic lesions after methotrexate withdrawal in patients pathologically diagnosed with methotrexate-associated lymphoproliferative disorders (MTX-LPD). In total, 89 lesions extracted from 24 patients on CT scans were included in the analysis. All patients had been evaluated for the presence of necrosis within lesions via CT scan upon first suspicion of MTX-LPD (baseline CT scan). The percentage lesion size reduction between the baseline and initial follow-up CT scan was calculated. The association between necrosis within lesions and size changes was estimated via linear regression analyses using both crude and adjusted models. Necrosis was significantly more common in extranodal lesions (27 out of 30 lesions, 90%) than in nodal lesions (9 out of 59 lesions, 15%, p<0.001). In the crude model, the regression of necrotic lesions was 58.5% greater than that of non-necrotic lesions; the difference was statistically significant (p<0.001). Additionally, the longest diameter of necrotic lesions at the baseline CT scan was significantly greater than that of non-necrotic lesions (p<0.001). Based on the adjusted model, necrotic lesions showed 49.3% greater regression than non-necrotic lesions (p=0.017). Necrosis detected on a CT scan was found to be an independent predictor of regression after MTX withdrawal in patients with MTX-LPD. |
| Keywords | methotrexate lymphoproliferative disorder computed tomography necrosis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2024-02 |
| Volume | volume78 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 29 |
| End Page | 36 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 38419312 |
| Web of Science KeyUT | 001203658200001 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tamura, Shuta| Tazawa, Hiroshi| Hori, Naoto| Li, Yuncheng| Yamada, Motohiko| Kikuchi, Satoru| Kuroda, Shinji| Urata, Yasuo| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| |
| Published Date | 2023-11-16 |
| Publication Title | PLoS ONE |
| Volume | volume18 |
| Issue | issue11 |
| Publisher | Public Library of Science |
| Start Page | e0294491 |
| ISSN | 1932-6203 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Tamura et al. |
| File Version | publisher |
| PubMed ID | 37972012 |
| DOI | 10.1371/journal.pone.0294491 |
| Web of Science KeyUT | 001119675000083 |
| Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0294491 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Okatani, Takeshi| Nishimura, Midori Filiz| Egusa, Yuria| Yoshida, Sayako| Nishimura, Yoshito| Nishikori, Asami| Yoshino, Tadashi| Yamamoto, Hidetaka| Sato, Yasuharu| |
| Keywords | methotrexate-associated lymphoproliferative disorders other iatrogenic immunodeficiency-associated lymphoproliferative disorders lymphoproliferative disorders arising in immune deficiency/dysregulation NOTCH1 |
| Published Date | 2024 |
| Publication Title | Journal of Clinical and Experimental Hematopathology |
| Volume | volume64 |
| Issue | issue1 |
| Publisher | Japanese Society for Lymphoreticular Tissue Research |
| Start Page | 1 |
| End Page | 9 |
| ISSN | 1346-4280 |
| NCID | AA11556796 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2024 The Japanese Society for Lymphoreticular Tissue Research |
| File Version | publisher |
| PubMed ID | 38281745 |
| DOI | 10.3960/jslrt.23038 |
| Web of Science KeyUT | 001155420800001 |
| Related Url | isVersionOf https://doi.org/10.3960/jslrt.23038 |
| FullText URL | fulltext20240206-04.pdf |
|---|---|
| Author | Sato, Yukiyo| Suzuki, Nobuhiro| |
| Note | © 2023 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Jun. 2024.| |
| Published Date | 2023-10 |
| Publication Title | Current Opinion in Microbiology |
| Volume | volume75 |
| Publisher | Elsevier |
| Start Page | 102337 |
| ISSN | 1369-5274 |
| NCID | AA11313229 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Elsevier Ltd. |
| File Version | author |
| PubMed ID | 37343415 |
| DOI | 10.1016/j.mib.2023.102337 |
| Web of Science KeyUT | 001025990600001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.mib.2023.102337 |
| FullText URL | fulltext20240109-01.pdf fig1_20240109-01.pdf fig2_20240109-01.pdf fig3_20240109-01.pdf fig4_20240109-01.pdf |
|---|---|
| Author | Okada, Koki| Morimoto, Yu| Shiraishi, Yukine| Tamura, Takashi| Mayama, Shigeki| Kadono, Takashi| Adachi, Masao| Ifuku, Kentaro| Nemoto, Michiko| |
| Keywords | Diatom Genetic transformation Nitzschia Multi-pulse electroporation |
| Note | This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s10126-023-10273-w| This fulltext file will be available in Dec. 2024.| |
| Published Date | 2023-12-10 |
| Publication Title | Marine Biotechnology |
| Volume | volume25 |
| Issue | issue6 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 1208 |
| End Page | 1219 |
| ISSN | 1436-2228 |
| NCID | AA11357643 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023 |
| File Version | author |
| PubMed ID | 38071657 |
| DOI | 10.1007/s10126-023-10273-w |
| Web of Science KeyUT | 001120097200001 |
| Related Url | isVersionOf https://doi.org/10.1007/s10126-023-10273-w |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Katoh, Hirokazu| Honda, Tomoyuki| |
| Keywords | HERVs LINEs cancer innate immunity promoter enhancer interferon signaling |
| Published Date | 2023-11-24 |
| Publication Title | Biomolecules |
| Volume | volume13 |
| Issue | issue12 |
| Publisher | MDPI |
| Start Page | 1706 |
| ISSN | 2218-273X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 38136578 |
| DOI | 10.3390/biom13121706 |
| Web of Science KeyUT | 001131322800001 |
| Related Url | isVersionOf https://doi.org/10.3390/biom13121706 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Taketa, Shin| Kim, June-Sik| Takahashi, Hidekazu| Yajima, Shunsuke| Koshiishi, Yuichi| Sotome, Toshinori| Kato, Tsuneo| Mochida, Keiichi| |
| Keywords | genetic diversity Hordeum vulgare RNA-sequencing seed transcriptome single nucleotide polymorphism virus disease resistance genes |
| Published Date | 2023 |
| Publication Title | Breeding Science |
| Volume | volume73 |
| Issue | issue5 |
| Publisher | Japanese Society of Breeding |
| Start Page | 435 |
| End Page | 444 |
| ISSN | 1344-7610 |
| NCID | AA11353132 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Japanese Society of Breeding. |
| File Version | publisher |
| DOI | 10.1270/jsbbs.23031 |
| Web of Science KeyUT | 001101195500001 |
| Related Url | isVersionOf https://doi.org/10.1270/jsbbs.23031 |
| FullText URL | K0006908_abstract_review.pdf K0006908_fulltext.pdf K0006908_other_figure.pdf K0006908_other_Supplementalry Table.pdf K0006908_other_Supplementary Figures.pdf K0006908_summary.pdf |
|---|---|
| Author | KAJIWARA, Yoshinori| |
| Published Date | 2023-09-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6908号 |
| Granted Date | 2023-09-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nishihata, Yu| Liu, Ziang| Nishi, Tatsushi| |
| Keywords | inventory management SEIR model evolutionary game theory |
| Published Date | 2023-10-14 |
| Publication Title | Applied Sciences |
| Volume | volume13 |
| Issue | issue20 |
| Publisher | MDPI |
| Start Page | 11308 |
| ISSN | 2076-3417 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| DOI | 10.3390/app132011308 |
| Web of Science KeyUT | 001090619000001 |
| Related Url | isVersionOf https://doi.org/10.3390/app132011308 |
| FullText URL | fulltext20231110-01.pdf |
|---|---|
| Author | Dansako, Hiromichi| Ikeda, Masanori| Ariumi, Yasuo| Togashi, Yosuke| Kato, Nobuyuki| |
| Keywords | double-stranded RNA hepatitis C virus innate immunity RIG-I-like receptor RNA virus |
| Note | This is the accepted version of the following article: Dansako, H., Ikeda, M., Ariumi, Y., Togashi, Y. and Kato, N. (2024), Hepatitis C virus NS5B triggers an MDA5-mediated innate immune response by producing dsRNA without the replication of viral genomes. FEBS J, 291: 1119-1130. https://doi.org/10.1111/febs.16980, which has been published in final form at https://doi.org/10.1111/febs.16980| This fulltext file will be available in Oct. 2024.| |
| Published Date | 2023-10-20 |
| Publication Title | The FEBS Journal |
| Volume | volume291 |
| Issue | issue6 |
| Publisher | Wiley |
| Start Page | 1119 |
| End Page | 1130 |
| ISSN | 1742-464X |
| NCID | AA11998513 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Federation of European Biochemical Societies. |
| File Version | author |
| PubMed ID | 37863517 |
| DOI | 10.1111/febs.16980 |
| Web of Science KeyUT | 001091349500001 |
| Related Url | isVersionOf https://doi.org/10.1111/febs.16980 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Shinoda, Sumio| |
| Keywords | COVID-19 SARS-CoV-2 vaccine Spanish flu influenza |
| Published Date | 2022-01-30 |
| Publication Title | Journal of Disaster Research |
| Volume | volume17 |
| Issue | issue1 |
| Publisher | Fuji Technology Press Ltd. |
| Start Page | 65 |
| End Page | 72 |
| ISSN | 1883-8030 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Fuji Technology Press Ltd. |
| File Version | publisher |
| DOI | 10.20965/jdr.2022.p0065 |
| Web of Science KeyUT | 000748695600008 |
| Related Url | isVersionOf https://doi.org/10.20965/jdr.2022.p0065 |
| FullText URL | fulltext20230829-01.pdf |
|---|---|
| Author | Sato, Yukiyo| Hisano, Sakae| Suzuki, Nobuhiro| |
| Keywords | Virus-virus interaction RNA viruses Capsidless Fungal viruses Plant pathogenic fungi Yadokarivirus Megabirnavirus Reverse genetics |
| Published Date | 2023-09 |
| Publication Title | Virus Research |
| Volume | volume334 |
| Publisher | Elsevier BV |
| Start Page | 199155 |
| ISSN | 0168-1702 |
| NCID | AA10642076 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 The Author(s). |
| File Version | publisher |
| PubMed ID | 37356581 |
| DOI | 10.1016/j.virusres.2023.199155 |
| Web of Science KeyUT | 001038861300001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.virusres.2023.199155 |
| JaLCDOI | 10.18926/AMO/65748 |
|---|---|
| FullText URL | 77_4_377.pdf |
| Author | Morimoto, Kosaku| Takeuchi, Yasuto| Takaki, Akinobu| Wada, Nozomu| Oyama, Atsushi| Adachi, Takuya| Onishi, Hideki| Shiraha, Hidenori| Okada, Hiroyuki| |
| Abstract | Liver fibrosis is an important phenomenon in non-alcoholic fatty liver disease (NAFLD) progression. Standard markers reflecting liver fibrosis, including the FIB-4 index, increase with age. This study aimed to identify fibrosis progression-related markers that are diagnostically beneficial even in aged individuals. Serum levels of pro- and anti-inflammatory cytokines were measured by multiple enzyme-linked immunosorbent assay. Two standard NAFLD or fibrosis progression-related markers — the FIB-4 index and APRI score — were analyzed along with cytokine levels to define the best approach to discriminate advanced fibrosis. Ninety-eight NAFLD patients were enrolled: 59 and 39 patients with fibrosis stages 1-2 and 3-4 respectively. In addition to the FIB-4 index and APRI score, the following factors showed significant differences between stages 1-2 and stages 3-4 in a multivariate analysis: platelet counts, IP-10, and RANTES. The fibrosis stage, FIB-4, APRI, PDGF-BB, and RANTES were related to the prognosis. In aged patients, IP-10, GM-CSF, and RANTES differed between stages 1-2 and stages 3-4. FIB-4 and APRI were beneficial for their correlation with fibrosis. However, to stratify either young or elderly advanced fibrosis patients, and to identify patients likely to have a bad outcome, RANTES was the best marker. |
| Keywords | NAFLD NASH liver fibrosis chemokine FIB-4 |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-08 |
| Volume | volume77 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 377 |
| End Page | 385 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37635138 |
| Web of Science KeyUT | 001163659800009 |
| JaLCDOI | 10.18926/AMO/65739 |
|---|---|
| FullText URL | 77_4_341.pdf |
| Author | Otsuka, Motoyuki| |
| Abstract | Hepatitis B virus is a pathogenic virus that infects 300 million people worldwide and causes chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. Hepatitis B virus encodes four proteins. Among them, the HBx protein plays a central role in the HBV pathogenesis. Because the HBx protein is considered to play a central role in the induction of viral replication and hepatocarcinogenesis, the regulation of its function could be a key factor in the development of new interventions against hepatitis B. In this review, HBx protein-related viral replication and hepatocarcinogenesis mechanisms are described, with a focus on the recently reported viral replication mechanisms related to degradation of the Smc5/6 protein complex. We also discuss our recent discovery of a compound that inhibits HBx protein-induced degradation of the Smc5/6 protein complex, and that exerts inhibitory effects on both viral replication and hepatocarcinogenesis. Finally, prospects for future research on the HBx protein are described. |
| Keywords | HBx Smc5/6 DDB1 nitazoxianide DNA repair |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-08 |
| Volume | volume77 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 341 |
| End Page | 345 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37635133 |
| Web of Science KeyUT | 001163659800007 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Gohda, Eiichi| |
| Keywords | COVID-19 SARS-CoV-2 mRNA vaccine immune response |
| Published Date | 2022-01-30 |
| Publication Title | Journal of Disaster Research |
| Volume | volume17 |
| Issue | issue1 |
| Publisher | Fuji Technology Press Ltd. |
| Start Page | 7 |
| End Page | 20 |
| ISSN | 1883-8030 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Fuji Technology Press Ltd. |
| File Version | publisher |
| DOI | 10.20965/jdr.2022.p0007 |
| Web of Science KeyUT | 000748695600002 |
| Related Url | isVersionOf https://doi.org/10.20965/jdr.2022.p0007 |
| FullText URL | K0006770_abstract_review.pdf K0006770_fulltext.pdf K0006770_other_Graphical_Abstract.pdf K0006770_other_fig.pdf K0006770_other_suppl.pdf K0006770_summary.pdf |
|---|---|
| Author | ARAKI, Hiroyuki| |
| Published Date | 2023-03-24 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6770号 |
| Granted Date | 2023-03-24 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | © 2022 The Author(s). |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Teng, Da| Ueda, Keiji| Honda, Tomoyuki| |
| Keywords | antiviral Borna disease virus neuronal cells gene expression differentiation |
| Published Date | 2023-04-10 |
| Publication Title | Viruses |
| Volume | volume15 |
| Issue | issue4 |
| Publisher | MDPI |
| Start Page | 942 |
| ISSN | 1999-4915 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 37112922 |
| DOI | 10.3390/v15040942 |
| Web of Science KeyUT | 000979538200001 |
| Related Url | isVersionOf https://doi.org/10.3390/v15040942 |
