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Author Iguchi, Toshihiro| Matsui, Yusuke| Toji, Tomohiro| Sakurai, Jun| Tomita, Koji| Uka, Mayu| Umakoshi, Noriyuki| Kawabata, Takahiro| Munetomo, Kazuaki| Mitsuhashi, Toshiharu| Hiraki, Takao|
Keywords Biopsy Kidney Tumor Computed tomography Ultrasound
Note The version of record of this article, first published in Japanese Journal of Radiology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s11604-023-01496-x|
Published Date 2023-10-14
Publication Title Japanese Journal of Radiology
Volume volume42
Issue issue3
Publisher Springer Science and Business Media LLC
Start Page 319
End Page 325
ISSN 1867-1071
NCID AA12375935
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023
File Version publisher
PubMed ID 37833443
DOI 10.1007/s11604-023-01496-x
Web of Science KeyUT 001086535200001
Related Url isVersionOf https://doi.org/10.1007/s11604-023-01496-x
JaLCDOI 10.18926/AMO/66924
FullText URL 78_2_151.pdf
Author Komatsubara, Tadashi| Tazawa, Hiroshi| Hasei, Joe| Omori, Toshinori| Sugiu, Kazuhisa| Mochizuki, Yusuke| Demiya, Koji| Yoshida, Aki| Fujiwara, Tomohiro| Kunisada, Toshiyuki| Urata, Yasuo| Kagawa, Shunsuke| Ozaki, Toshifumi| Fujiwara, Toshiyoshi|
Abstract Soft-tissue sarcoma (STS) is a heterogeneous group of rare tumors originating predominantly from the embryonic mesoderm. Despite the development of combined modalities including radiotherapy, STSs are often refractory to antitumor modalities, and novel strategies that improve the prognosis of STS patients are needed. We previously demonstrated the therapeutic potential of two telomerase-specific replication-competent oncolytic adenoviruses, OBP-301 and tumor suppressor p53-armed OBP-702, in human STS cells. Here, we demonstrate in vitro and in vivo antitumor effects of OBP-702 in combination with ionizing radiation against human STS cells (HT1080, NMS-2, SYO-1). OBP-702 synergistically promoted the antitumor effect of ionizing radiation in the STS cells by suppressing the expression of B-cell lymphoma-X large (BCL-xL) and enhancing ionizing radiation-induced apoptosis. The in vivo experiments demonstrated that this combination therapy significantly suppressed STS tumors’ growth. Our results suggest that OBP-702 is a promising antitumor reagent for promoting the radiosensitivity of STS tumors.
Keywords soft-tissue sarcoma radiotherapy oncolytic adenovirus p53 BCL-xL
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 151
End Page 161
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688833
Web of Science KeyUT 001229151800007
JaLCDOI 10.18926/AMO/66923
FullText URL 78_2_143.pdf
Author Shigematsu, Hisayuki| Yamashita, Natsumi| Suehisa, Hiroshi| Ueno, Tsuyoshi| Ryuko, Tsuyoshi| Sugihara, Takahito| Nakashima, Shohei| Sano, Yoshifumi| Yamashita, Motohiro|
Abstract Travel burden is a poor prognostic factor for many cancers worldwide because it hinders optimal diagnosis and treatment planning. Currently, the impact of travel burden on survival after surgery for non-small cell lung cancer (NSCLC) in Japan is largely unexplored. We examined the impact of travel distance on the postoperative outcomes of patients with NSCLC in Ehime Prefecture, Japan. The data of 1212 patients who underwent surgical resection for NSCLC were retrospectively reviewed. Patients were divided into quartiles based on the travel distance from their home to the hospital (≤ 13 km, 13-40 km, 40-57 km, and > 57 km) in Ehime Prefecture. We found no significant differences among the quartiles in baseline clinicopathological characteristics, including sex, smoking status, histology, surgical procedure, clinical stage, and pathological stage. Overall survival (OS) and relapse-free survival (RFS) also were not significantly different among the travel distance quartiles. We conclude that travel distance did not impact OS or RFS among patients with NSCLC who underwent surgical resection at our institution.
Keywords non-small cell lung cancer travel distance travel burden lung surgery surgical outcome
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 143
End Page 149
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688832
Web of Science KeyUT 001229151800006
FullText URL fulltext.pdf
Author Nakamitsu, Yuki| Kuroda, Masahiro| Shimizu, Yudai| Kuroda, Kazuhiro| Yoshimura, Yuuki| Yoshida, Suzuka| Nakamura, Yoshihide| Fukumura, Yuka| Kamizaki, Ryo| Al-Hammad, Wlla E.| Oita, Masataka| Tanabe, Yoshinori| Sugimoto, Kohei| Sugianto, Irfan| Barham, Majd| Tekiki, Nouha| Asaumi, Junichi|
Keywords diffusion-weighted image Gaussian filter head and neck tumor magnetic resonance imaging mean kurtosis median filter nonlocal mean filter phantom simple diffusion kurtosis imaging restricted diffusion-weighted image
Published Date 2024-03-20
Publication Title Journal of Clinical Medicine
Volume volume13
Issue issue6
Publisher MDPI
Start Page 1783
ISSN 2077-0383
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 38542005
DOI 10.3390/jcm13061783
Web of Science KeyUT 001192756600001
Related Url isVersionOf https://doi.org/10.3390/jcm13061783
FullText URL fulltext.pdf
Author Mitoma, Tomohiro| Maki, Jota| Ooba, Hikaru| Ogawa, Chikako| Masuyama, Hisashi| Tabuchi, Takahiro|
Keywords cervical cancer screening social inequality screening hesitation internet survey
Published Date 2024-02-13
Publication Title International Journal of General Medicine
Volume volume17
Publisher Dove Press
Start Page 541
End Page 551
ISSN 1178-7074
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Mitoma et al.
File Version publisher
PubMed ID 38371520
DOI 10.2147/IJGM.S453675
Web of Science KeyUT 001162765400001
Related Url isVersionOf https://doi.org/10.2147/IJGM.S453675
Title Alternative Formation Process of the Operating System on Patent Law in Postwar Japan
FullText URL olj_73_3_201_260.pdf
Author Oizumi, Y.|
Publication Title Okayama Law Journal
Published Date 2024-02-26
Volume volume73
Issue issue3
Start Page 260
End Page 201
ISSN 0386-3050
language Japanese
File Version publisher
FullText URL fulltext.pdf
Author Matsumoto, Kazuya| Matsumoto, Yoshinori| Nawachi, Shoichi| Asano, Yosuke| Katayama, Yu| Miyawaki, Yoshia| Katsuyama, Takayuki| Katsuyama, Eri| Nasu, Yoshihisa| Sada, Ken-Ei| Wada, Jun|
Keywords Nail-patella syndrome Rheumatoid arthritis Joint dislocation Iliac horn Case report
Note The version of record of this article, first published in BMC Musculoskeletal Disorders, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12891-024-07242-2|
Published Date 2024-02-14
Publication Title BMC Musculoskeletal Disorders
Volume volume25
Issue issue1
Publisher BMC
Start Page 139
ISSN 1471-2474
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024.
File Version publisher
PubMed ID 38355529
DOI 10.1186/s12891-024-07242-2
Web of Science KeyUT 001162669400002
Related Url isVersionOf https://doi.org/10.1186/s12891-024-07242-2
JaLCDOI 10.18926/AMO/66673
FullText URL 78_1_071.pdf
Author Kaneda, Daisuke| Nishida, Keiichiro| Nasu, Yoshihisa| Nakahara, Ryuichi| Harada, Ryozo| Hotta, Yoshifumi| Naniwa, Shuichi| Ozaki, Toshifumi|
Abstract We retrospectively investigated the mid-term outcomes of arthroplasty using the AVANTA silicone implant for thumb metacarpophalangeal (MCP) joints with boutonniere deformity in patients with rheumatoid arthritis (RA). This study involved 36 thumbs of 33 RA patients with a mean follow-up period of 5.1 years (range, 2.0-13.3). Postoperatively, the mean extension was significantly increased and the mean flexion was significantly decreased (p<0.001, p<0.001, respectively), resulting in the mean arc of range of motion (ROM) shifting in the direction of extension after surgery. Implant fracture was observed in 10 thumbs (28%), and 4 of these (11%) underwent revision surgery. The survivorship with implant fracture and revision surgery as endpoints were 73.4% and 91.8% at 5 years, respectively. The preoperative arc of ROM and the postoperative flexion range of the implant-fracture group were significantly greater than those in the no-implant-fracture group (p=0.039, 0.034, respectively). These results suggest the importance of patient education and careful rehabilitation to prevent excessive flexion. Overall, the AVANTA silicone implant showed a relatively high rate of implant fracture at our institute.
Keywords AVANTA silicone implant boutonniere deformity implant fracture thumb metacarpophalangeal joint arthroplasty rheumatoid arthritis
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-02
Volume volume78
Issue issue1
Publisher Okayama University Medical School
Start Page 71
End Page 78
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38419317
Web of Science KeyUT 001203658200011
FullText URL fulltext.pdf
Author Wakabayashi, Shoki| Oh, Yuki| Nakayama, Haruhito| Wang, Jin| Kiwa, Toshihiko|
Keywords hydrogen sensor ultrathin film twin-T notch filter platinum
Published Date 2024-01-15
Publication Title Sensors
Volume volume24
Issue issue2
Publisher MDPI
Start Page 548
ISSN 1424-8220
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 38257641
DOI 10.3390/s24020548
Web of Science KeyUT 001151362100001
Related Url isVersionOf https://doi.org/10.3390/s24020548
FullText URL fulltext20240123-02.pdf
Author Takatsu, Fumiaki| Suzawa, Ken| Okazaki, Mikio| Shien, Kazuhiko| Yamamoto, Hiromasa| Watanabe, Mototsugu| Hayama, Makio| Ueno, Tsuyoshi| Sugimoto, Ryujiro| Maki, Yuho| Fujiwara, Toshiya| Okita, Riki| Inokawa, Hidetoshi| Tao, Hiroyuki| Hirami, Yuji| Matsuda, Eisuke| Kataoka, Kazuhiko| Yamashita, Motohiro| Sano, Yoshifumi| Matsuura, Motoki| Mizutani, Hisao| Toyooka, Shinichi|
Note © 2024 by The Society of Thoracic Surgeons. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Dec. 2024.|
Published Date 2024-01
Publication Title The Annals of Thoracic Surgery
Volume volume117
Issue issue1
Publisher Elsevier BV
Start Page 181
End Page 188
ISSN 0003-4975
NCID AA00533201
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by The Society of Thoracic Surgeons
File Version author
PubMed ID 35595090
DOI 10.1016/j.athoracsur.2022.04.052
Web of Science KeyUT 001137577900001
Related Url isVersionOf https://doi.org/10.1016/j.athoracsur.2022.04.052
FullText URL fulltext.pdf
Author Ando, Kakeru| Watanabe, Minoru| Watanabe, Nobuya|
Note © 2023 Optica Publishing Group. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for non-commercial purposes and appropriate attribution is maintained. All other rights are reserved.|
Published Date 2023-11-06
Publication Title Optics Express
Volume volume31
Issue issue23
Publisher Optica Publishing Group
Start Page 38529
End Page 38539
ISSN 1094-4087
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement
File Version publisher
PubMed ID 38017956
DOI 10.1364/OE.500666
Web of Science KeyUT 001108090500007
Related Url isVersionOf https://doi.org/10.1364/OE.500666
FullText URL fulltext.pdf
Author Saito, Taichi| Nakamichi, Ryo| Nakahara, Ryuichi| Nishida, Keiichiro| Ozaki, Toshifumi|
Keywords hand surgery rehabilitation open surgical release trigger finger
Published Date 2023-11-20
Publication Title Journal of Clinical Medicine
Volume volume12
Issue issue22
Publisher MDPI
Start Page 7187
ISSN 2077-0383
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
PubMed ID 38002801
DOI 10.3390/jcm12227187
Web of Science KeyUT 001123419500001
Related Url isVersionOf https://doi.org/10.3390/jcm12227187
Title Alternative Water usage, flooding, and the Takao family at Senjū-nakagumi in the Meiji period: A case study of the Minuma substitute canal (Minuma-daiyōsui)
JaLCDOI 10.18926/66194
FullText URL jdc_003_079.pdf
Author MIMURA, Shoji|
Abstract This paper examines the maintenance work of the Minuma Substitute Canal by the Meiji Government and how Noriyoshi Takao who lived at Senjū-nakagumi was involved in it. In the 1880s, when the cost of maintaining the Minuma Substitute Canal was shifted from government expenditures to private ones, the early modern water usage system was on the verge of being converted to a modern one. This meant that the system, which was based on villages or ryō (領), transformed into one based on individuals, especially landowners. The village served as a cost-sharing unit during the Meiji period. Ryō (領) were operated in the downstream water of the Minuma Substitute Canal where there were no critical structures. However, districts (郡) supervised the water usage of ryō, creating a multilayered local community in terms of water usage.
Keywords water usage floods modern Japan
Amo Type 特集:災害と文明・地域社会 (Special Issue: Disasters, civilization, and local society)
Publication Title Dynamics of Civilizations
Published Date 2024-03-25
Volume volume3
Publisher 岡山大学文明動態学研究所
Start Page 79
End Page 91
ISSN 2436-8326
Content Type Journal Article
language Japanese
Copyright Holders © 2024 by RIDC
File Version publisher
JaLCDOI 10.18926/AMO/66160
FullText URL 77_6_665.pdf
Author Sakurai, Atsunobu| Uka, Mayu| Iguchi, Toshihiro| Tomita, Koji| Matsui, Yusuke| Kakiuchi, Yoshihiko| Kuroda, Shinji| Fujiwara, Toshiyoshi| Hiraki, Takao|
Abstract We report the case details of a 65-year-old Japanese man with an omental abscess that was discovered 43 days after he underwent a laparoscopic proximal gastrectomy for gastric cancer. His chief complaint was mild abdominal pain that had persisted for several days. The abscess was diagnosed as a rare postoperative complication. We hesitated to perform a reoperation given the invasiveness of general anesthesia and surgery, plus the possibility of postoperative adhesions and because the patient’s general condition was stable and he had only mild abdominal pain. Percutaneous drainage using a 10.2-F catheter was performed with the patient under conscious sedation and computed tomography–fluoroscopy guidance, with no complications. After the procedure, the size of the abscess cavity was remarkably reduced, and 23 days later the catheter was withdrawn.
Keywords drainage omental abscess omental infarction proximal gastrectomy
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-12
Volume volume77
Issue issue6
Publisher Okayama University Medical School
Start Page 665
End Page 669
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38145942
Web of Science KeyUT 001164631200013
JaLCDOI 10.18926/AMO/66159
FullText URL 77_6_655.pdf
Author Endo, Hirosuke| Yamada, Kazuki| Tetsunaga, Tomonori| Namba, Yoshifumi| Sugimoto, Yoshihisa| Mitani, Shigeru| Nakata, Eiji| Ozaki, Toshifumi|
Abstract Most patients with developmental dysplasia of the hip (DDH) now receive closed-reduction treatment within 6 months after birth. The long-term outcomes of patients with late-detection DDH have remained unclear. We reviewed the clinical records of 18 patients who underwent Colonna capsular arthroplasty (n=8) or closed reduction (n=10) for developmental dysplasia of the hip as infants or young children and underwent total hip arthroplasty approximately in midlife. Both the Colonna capsular arthroplasty and closed reduction groups achieved good clinical results after total hip arthroplasty. However, the operating time was longer and the improvements of hip range of motion and clinical score were significantly worse in the Colonna capsular arthroplasty group than in the closed reduction group.
Keywords developmental hip dysplasia long-term follow-up closed reduction Colonna capsular arthroplasty total hip arthroplasty
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-12
Volume volume77
Issue issue6
Publisher Okayama University Medical School
Start Page 655
End Page 663
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38145941
Web of Science KeyUT 001164631200012
JaLCDOI 10.18926/AMO/66156
FullText URL 77_6_635.pdf
Author Ikeda, Tomohiro| Okamura, Kazunori| Hasegawa, Masaki| Tanaka, Satoshi| Kanai, Shusaku|
Abstract In the management of post-injury patients with activity limitations, methods to prevent musculoskeletal disorders and hasten recovery are important. This randomized controlled, single-blinded study was a preliminary investigation of the combined effect of nutritional support with neuromuscular electrical stimulation (NMES) on muscle strength and thickness. Healthy young adult males (median age, 21 years) were enrolled; each of their hands was randomly assigned to one of the following four groups: Placebo, Nutrition, NMES, and Nutrition + NMES. All participants received whey protein or placebo (3x/week for 6 weeks) and NMES training (3x/week for 6 weeks) on the abductor digiti minimi (ADM) muscle of either the left or right hand. ADM muscle strength and thickness were analyzed at baseline and at week 7. We analyzed 38 hands (9 Placebo, 10 Nutrition, 9 NMES, 10 Nutrition + NMES). There was significantly greater muscle strengthening in the Nutrition + NMES group compared to the Placebo group or the NMES group, but no significant difference in gain of muscle thickness. The combined intervention may be effective in improving muscle strength. Future clinical trials targeting various muscles after sports-related injuries are warranted.
Keywords whey protein electrical stimulation muscle strength healthy volunteers
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-12
Volume volume77
Issue issue6
Publisher Okayama University Medical School
Start Page 635
End Page 645
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38145938
Web of Science KeyUT 001164631200009
JaLCDOI 10.18926/AMO/66154
FullText URL 77_6_619.pdf
Author Oe, Kenichi| Iida, Hirokazu| Sogawa, Shohei| Kobayashi, Fumito| Nakamura, Tomohisa| Saito, Takanori|
Abstract This study retrospectively evaluated 41 consecutive open reductions and internal fixations following primary or revision total hip arthroplasty, which required trochanteric claw plate fixation for greater trochanteric fracture or osteotomy between January 2008 and December 2020. The mean duration of clinical follow-up was 4.2 years (range, 1-13 years). The patients included 13 men and 28 women, with a mean age of 68 years (range, 32-87 years). The indications for intervention included trochanteric osteotomy, intraoperative fracture, and non-union including postoperative fracture in 6, 9, and 26 cases, respectively. The mean Merle d’Aubigné Clinical Score improved from 9.4 points (range, 5-15 points) pre-operatively, to 14.3 points (range, 9-18 points) at the last follow-up. Bone union occurred in 35 cases (85%), while implant breakage occurred in four cases. At the last follow-up, the mean Merle d’Aubigné Clinical Scores of bone union and non-union were 15.3 and 14.1, respectively (p=0.48). The Kaplan-Meier survival rate, with the endpoint being revision surgery for pain, non-union, dislocation, or implant breakage, at 10 years was 80.0% (95% confidence interval: 62.6-97.4%). Greater trochanteric fixation using a trochanteric claw plate yielded successful results.
Keywords greater trochanteric fracture trochanteric osteotomy claw plate total hip arthroplasty
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-12
Volume volume77
Issue issue6
Publisher Okayama University Medical School
Start Page 619
End Page 625
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38145936
Web of Science KeyUT 001164631200007
FullText URL K0006944_abstract_review.pdf K0006944_fulltext.pdf
Author SUGIMOTO, Kohei|
Published Date 2023-09-25
Content Type Thesis or Dissertation
Grant Number 甲第6944号
Granted Date 2023-09-25
Thesis Type Doctor of Philosophy
Grantor 岡山大学
language Japanese
FullText URL fulltext.pdf
Author Taoka, Masataka| Makimoto, Go| Umakoshi, Noriyuki| Ninomiya, Kiichiro| Higo, Hisao| Kato, Yuka| Fujii, Masanori| Kubo, Toshio| Ichihara, Eiki| Ohashi, Kadoaki| Hotta, Katsuyuki| Tabata, Masahiro| Maeda, Yoshinobu| Kiura, Katsuyuki|
Keywords Hemoptysis Bronchial artery embolization Endoscopic bronchial occlusion Endobronchial Watanabe Spigot
Published Date 2022
Publication Title Respiratory Medicine Case Reports
Volume volume38
Publisher Elsevier
Start Page 101669
ISSN 2213-0071
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Authors.
File Version publisher
PubMed ID 35646587
DOI 10.1016/j.rmcr.2022.101669
Web of Science KeyUT 001089212200003
Related Url isVersionOf https://doi.org/10.1016/j.rmcr.2022.101669
FullText URL fulltext.pdf
Author Ueda, Hiroshi| Maeda, Hideaki| Suetomi, Yu| Yanagisawa, Yoshinori|
Keywords REBCO magnet screening current mechanical stress combined effect
Published Date 2022-03-21
Publication Title Superconductor Science and Technology
Volume volume35
Issue issue5
Publisher IOP Publishing
Start Page 054001
ISSN 0953-2048
NCID AA10686810
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Author(s).
File Version publisher
DOI 10.1088/1361-6668/ac4b9e
Web of Science KeyUT 000771192800001
Related Url isVersionOf https://doi.org/10.1088/1361-6668/ac4b9e