result 18817 件
| FullText URL | fulltext.pdf suppl.pdf |
|---|---|
| Author | Nguyen, Phuoc Quy Thang| Watanabe, Yuta| Matsui, Hidenori| Sakata, Nanami| Noutoshi, Yoshiteru| Toyoda, Kazuhiro| Ichinose, Yuki| |
| Keywords | chemoreceptor formate mcpF Pseudomonas syringae virulence |
| Published Date | 2025 |
| Publication Title | Microbes and Environments |
| Volume | volume40 |
| Issue | issue3 |
| Publisher | Japanese Society of Microbial Ecology |
| Start Page | ME25019 |
| ISSN | 1342-6311 |
| NCID | AA11173196 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 by Japanese Society of Microbial Ecology / Japanese Society of Soil Microbiology / Taiwan Society of Microbial Ecology / Japanese Society of Plant Microbe Interactions / Japanese Society for Extremophiles. |
| File Version | publisher |
| PubMed ID | 40707216 |
| DOI | 10.1264/jsme2.me25019 |
| Web of Science KeyUT | 001551097000003 |
| Related Url | isVersionOf https://doi.org/10.1264/jsme2.me25019 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Shinohara, Hironori| Sharma, Manmohan D.| Pennell, Tanya M.| Okada, Kensuke| Hosken, David J.| |
| Keywords | inbreeding selection beetle Gnatocerus |
| Published Date | 2025-09-24 |
| Publication Title | Royal Society Open Science |
| Volume | volume12 |
| Issue | issue9 |
| Publisher | The Royal Society |
| Start Page | 251152 |
| ISSN | 2054-5703 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 The Authors. |
| File Version | publisher |
| PubMed ID | 40994570 |
| DOI | 10.1098/rsos.251152 |
| Web of Science KeyUT | 001576643100006 |
| Related Url | isVersionOf https://doi.org/10.1098/rsos.251152 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Hemelda, Niarsi Merry| Noutoshi, Yoshiteru| |
| Keywords | carbon sources plant-derived sugars plant-microbe interactions rhizosphere root exudate |
| Published Date | 2025-09-25 |
| Publication Title | Plant Biotechnology |
| Volume | volume42 |
| Issue | issue3 |
| Publisher | Japanese Society for Plant Cell and Molecular Biology |
| Start Page | 215 |
| End Page | 227 |
| ISSN | 1342-4580 |
| NCID | AA11250821 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 Japanese Society for Plant Biotechnology. |
| File Version | publisher |
| DOI | 10.5511/plantbiotechnology.25.0214a |
| Related Url | isVersionOf https://doi.org/10.5511/plantbiotechnology.25.0214a |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nagamine, Masanori| Nakao, Tomoyo| van Bergen, Leo| Shigemura, Jun| Saito, Taku| van der Does, Florentine H.S.| Kitano, Masato| Giltay, Erik J.| van der Wee, Nic J.| Vermetten, Eric| |
| Keywords | Psychotrauma World War II Japan Europe KZ syndrome Post-traumatic stress disorder |
| Published Date | 2025-06 |
| Publication Title | Asian Journal of Psychiatry |
| Volume | volume108 |
| Publisher | Elsevier BV |
| Start Page | 104508 |
| ISSN | 1876-2018 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 The Authors. |
| File Version | publisher |
| PubMed ID | 40287989 |
| DOI | 10.1016/j.ajp.2025.104508 |
| Web of Science KeyUT | 001482303000001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.ajp.2025.104508 |
| FullText URL | fulltext.pdf suppl1.pdf suppl2.xlsx |
|---|---|
| Author | Tanaka, Yoshitaka| Seki, Takahide| Hoshino, Atsushi| Ansai, Satoshi| |
| Keywords | Fish Medaka Morning glory Transgenic Transposon |
| Published Date | 2025-10-09 |
| Publication Title | Transgenic Research |
| Volume | volume34 |
| Issue | issue1 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 46 |
| ISSN | 0962-8819 |
| NCID | AA10873487 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2025 |
| File Version | publisher |
| PubMed ID | 41068540 |
| DOI | 10.1007/s11248-025-00466-5 |
| Web of Science KeyUT | 001590049100001 |
| Related Url | isVersionOf https://doi.org/10.1007/s11248-025-00466-5 |
| FullText URL | fulltext.pdf suppl.docx |
|---|---|
| Author | Tsuboi, Ichiro| Kardoust Parizi, Mehdi| Matsukawa, Akihiro| Miszczyk, Marcin| Fazekas, Tamás| Cormio, Angelo| Kawada, Tatsushi| Katayama, Satoshi| Iwata, Takehiro| Bekku, Kensuke| Wada, Koichiro| Karakiewicz, Pierre I.| Chlosta, Piotr| Briganti, Alberto| Araki, Motoo| Shariat, Shahrokh F.| |
| Keywords | Febrile urinary tract infection Targeted prophylactic antibiotics Transrectal prostate biopsy Sepsis |
| Published Date | 2025-10 |
| Publication Title | European Urology Open Science |
| Volume | volume80 |
| Publisher | Elsevier BV |
| Start Page | 57 |
| End Page | 65 |
| ISSN | 2666-1683 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 The Author(s). |
| File Version | publisher |
| PubMed ID | 41064532 |
| DOI | 10.1016/j.euros.2025.08.007 |
| Web of Science KeyUT | 001572715700001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.euros.2025.08.007 |
| FullText URL | fulltext.pdf suppl1.tif suppl2.tif suppl3.tif |
|---|---|
| Author | Tominaga, Yusuke| Kobayashi, Tomoko| Matsumoto, Yuko| Sako, Tomoko| Moriwake, Takatoshi| Horii, Satoshi| Sadahira, Takuya| Katayama, Satoshi| Iwata, Takehiro| Nishimura, Shingo| Bekku, Kensuke| Edamura, Kohei| Watanabe, Masami| Araki, Motoo| |
| Keywords | Finasteride Dihydrotestosterone Transgender men Androgenetic alopecia Resumption of menstruation |
| Published Date | 2025-09-29 |
| Publication Title | Journal of Medical Case Reports |
| Volume | volume19 |
| Issue | issue1 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 468 |
| ISSN | 1752-1947 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2025. |
| File Version | publisher |
| PubMed ID | 41024043 |
| DOI | 10.1186/s13256-025-05562-y |
| Web of Science KeyUT | 001585008600008 |
| Related Url | isVersionOf https://doi.org/10.1186/s13256-025-05562-y |
| JaLCDOI | 10.18926/AMO/69442 |
|---|---|
| FullText URL | 79_5_399.pdf |
| Author | Isozaki, Hiroshi| Matsumoto, Sasau| Takama, Takehiro| Isozaki, Yuka| Murakami, Shigeki| |
| Abstract | Gastric cancer with lymphoid stroma (GCLS) accounts for 1%-7% of gastric cancers; ~80% are Epstein-Barr virus (EBV)-positive. The rate of lymph node metastasis is relatively low, even when an early GCLS has invaded the submucosa. We report an early GCLS with massive submucosal invasion mimicking a submucosal tumor (SMT), diagnosed by endoscopic submucosal resection (ESD) and treated with local resection and sentinel node navigation surgery (SNNS). The patient was a 40-year-old Japanese man. A protruding lesion on the greater curvature of the middle part of his stomach was detected by X-ray, and an endoscopic examination revealed a 2.5-cm protruding tumor covered with a normal mucosa and small ulcers at the apex. ESD was performed for a diagnosis. The pathological diagnosis was lymphoepithelioma-like gastric cancer (GCLS), pT1b(SM2), Ly0, V0, pHM1, pVM1. EBV infection in the cancer cells was confirmed pathologically by EBV-encoded RNA. The local resection was performed using SNNS. The patient has had no recurrence or post-gastrectomy syndrome 4 years postsurgery. EBV-associated early GCLS resembling an SMT is relatively rare, and clinicians need to be aware of this disease. Local resection using SNNS may be a surgical option for GCLS cases with a low rate of lymphatic metastasis. |
| Keywords | gastric cancer gastric cancer with lymphoid stroma lymphoepithelioma-like carcinoma Epstein Barr virus sentinel node navigation surgery |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-10 |
| Volume | volume79 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 399 |
| End Page | 404 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| JaLCDOI | 10.18926/AMO/69441 |
|---|---|
| FullText URL | 79_5_393.pdf |
| Author | Masunaga, Akari| Takagi, Kosei| Nagai, Yasuo| Yasui, Kazuya| Fuji, Tomokazu| Yamada, Motohiko| Nishiyama, Takeyoshi| Kanehira, Noriyuki| Sota, Yumi| Fujiwara, Toshiyoshi| |
| Abstract | Pancreatoduodenectomy (PD) after esophagectomy with gastric conduit reconstruction is technically challenging. Preserving the blood supply of the gastric conduit is crucial in performing PD after esophagectomy. We report the case of a 66-year-old man who underwent gastroduodenal artery-preserving PD after esophagectomy with gastric conduit reconstruction for intraductal papillary mucinous neoplasm. The patient developed pseudoaneurysm rupture postoperatively, but was successfully treated with interventional radiology. Precise assessment is important in developing a surgical strategy depending on the patient’s specific anatomy and tumor characteristics. Moreover, special attention should be paid to avoid accidental injuries of the gastric conduit and gastric vessels during surgery. |
| Keywords | pancreatoduodenectomy esophagectomy gastric conduit fluorescence imaging |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-10 |
| Volume | volume79 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 393 |
| End Page | 398 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| JaLCDOI | 10.18926/AMO/69440 |
|---|---|
| FullText URL | 79_5_387.pdf |
| Author | Mori, Yusuke| Otani, Yoshihiro| Omae, Ryo| Hirano, Shuichiro| Ishida, Joji| Fujii, Kentaro| Haruma, Jun| Hiramatsu, Masafumi| Matsushita, Toshi| Higaki, Fumiyo| Sugiu, Kenji| Tanaka, Shota| |
| Abstract | Trigonal meningiomas are rare and pose surgical challenges due to their deep location and proximity to critical neuroanatomical structures. We present the case of a 67-year-old woman with a growing trigonal meningioma successfully resected with guidance by a preoperative 3D imaging analysis system. Integration of CT and MRI including diffusion tensor imaging (DTI) enabled precise mapping of the optic radiation, guiding a middle temporal gyrus approach. Preoperative embolization reduced tumor vascularity, facilitating gross total resection with minimal blood loss. This case highlights the effectiveness of preoperative 3D imaging systems in optimizing surgical planning and improving outcomes in complex neurosurgical cases. |
| Keywords | trigonal meningioma imaging analysis diffusion tensor imaging |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-10 |
| Volume | volume79 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 387 |
| End Page | 392 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| JaLCDOI | 10.18926/AMO/69439 |
|---|---|
| FullText URL | 79_5_381.pdf |
| Author | Sakurai, Atsunobu| Yabuki, Takayuki| Aoki, Hideki| Iseki, Akiko| |
| Abstract | We report the case of a 72-year-old Japanese man with an incidental portal vein mass that was surgically resected and diagnosed as immunoglobulin G4 (IgG4)-related disease. The mass was discovered during an atrial fibrillation examination. The patient had a history of gastric cancer and was also diagnosed with rectal cancer, raising concerns about metastasis. Due to technical challenges, a biopsy was not feasible. Imaging findings suggested portal vein tumor thrombosis, complicating the diagnosis. This case highlights a rare presentation of IgG4-related disease mimicking portal vein tumor thrombus. |
| Keywords | immunoglobulin G4-related disease inflammatory pseudotumor mass portal vein pericarditis |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-10 |
| Volume | volume79 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 381 |
| End Page | 385 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| JaLCDOI | 10.18926/AMO/69438 |
|---|---|
| FullText URL | 79_5_369.pdf |
| Author | Hisamatsu, Takashi| Kinuta, Minako| Munetomo, Sosuke| Fukuda, Mari| Kojima, Katsuhide| Taniguchi, Kaori| Nakahata, Noriko| Kanda, Hideyuki| |
| Abstract | We applied unsupervised machine learning to analyze blood pressure (BP) and resting heart rate (HR) patterns measured during a 1-year period to assess their cross-sectional relationships with subclinical cerebral and renal target damage. Dimension reduction via uniform manifold approximation and projection, followed by K-means++ clustering, was used to categorize 362 community-dwelling participants (mean age, 56.2 years; 54.9% women) into three groups: Low BP and Low HR (Lo-BP/Lo-HR), High BP and High HR (Hi-BP/Hi-HR), and Low BP and High HR (Lo-BP/Hi-HR). Cerebral vessel lesions were defined as the presence of at least one of the following magnetic resonance imaging findings: lacunar infarcts, white matter hyperintensities, cerebral microbleeds, or intracranial artery stenosis. A high urinary albumin-to-creatinine ratio (UACR) was defined as the top 10% (≥ 12 mg/g) of the mean value from ≥2 measurements. Poisson regression with robust error variance, adjusted for demographics, lifestyle, and medical history, showed that the Hi-BP/Hi-HR group had relative risks of 3.62 (95% confidence interval, 1.75-7.46) for cerebral vessel lesions and 3.58 (1.33-9.67) for high UACR, and the Lo-BP/Hi-HR group had a relative risk of 3.09 (1.12-8.57) for high UACR, compared with the Lo-BP/Lo-HR group. These findings demonstrate the utility of an unsupervised, data-driven approach for identifying physiological patterns associated with subclinical target organ damage. |
| Keywords | blood pressure heart rate subclinical disease uniform manifold approximation and projection unsupervised machine learning |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-10 |
| Volume | volume79 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 369 |
| End Page | 379 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| JaLCDOI | 10.18926/AMO/69437 |
|---|---|
| FullText URL | 79_5_359.pdf |
| Author | Hirose, Tomohiko| Ikuma, Hisanori| Otsuka, Kazutoshi| Kawasaki, Keisuke| |
| Abstract | Single-position surgery with lateral lumbar interbody fusion (LLIF) and percutaneous pedicle screws (PPSs) is gaining attention for its reduced invasiveness. We developed SPAPS, a technique allowing two surgeons to perform anterior LLIF and posterior PPS insertion simultaneously in a single lateral decubitus position. This retrospective study compared SPAPS (SPAPS-LLIF, Group SL) and minimally invasive posterior/transforaminal lumbar interbody fusion (MIS-PLIF/TLIF, Group PT) in patients treated between 2016 and 2019 with a two-year follow-up. Operative time, estimated blood loss (EBL), length of hospital stay (LOS), JOABPEQ and VAS scores, segmental lordotic angle, lumbar lordotic angle, segmental Cobb’s angle, PPS misplacement, PPS loosening, fusion status, and muscle cross-sectional areas were compared. Fifty-two patients were analyzed (Group SL: 25; Group PT: 27). SPAPS significantly reduced operative time (118.0 vs. 165.3 min, p <0.01) and estimated blood loss (8.6 vs. 164.1 mL, p<0.01). While clinical outcomes and hospital stay were comparable, Group SL had significantly lower PPS loosening (0% vs. 13%, p<0.01) and non-union rates (0% vs. 22.2%, p=0.02). Multifidus muscle atrophy was also less in Group SL (−14.3 vs. −121.5 mm2, p<0.01). SPAPS demonstrated advantages in reducing surgical invasiveness without compromising clinical efficacy, offering a promising alternative to conventional posterior fusion surgery. |
| Keywords | single-position surgery simultaneous lateral decubitus positioning lateral lumbar interbody fusion posterior lumbar interbody fusion |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-10 |
| Volume | volume79 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 359 |
| End Page | 368 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| JaLCDOI | 10.18926/AMO/69436 |
|---|---|
| FullText URL | 79_5_353.pdf |
| Author | Chihara, Yuki| Hamasaki, Ichiro| Shibata, Kiyo| Morisawa, Shin| Kono, Reika| Kanenaga, Keisuke| Morizane, Yuki| |
| Abstract | To analyze and characterize the medial and lateral rectus muscles in patients with exotropia using anterior segment optical coherence tomography (AS-OCT). This study included 24 patients with exotropia (48 eyes) and 25 healthy individuals (50 eyes). Anterior segment optical coherence tomography was used to construct the en face images. The anterior chamber angle to the extraocular muscle insertion distance, muscle width, and muscle fiber angle from the muscle insertion sites were compared between the exotropia and the control groups. The correlation between these parameters and age or angle of deviation was evaluated. The mean ages were 13.2±4.1 years for the exotropia group and 17.6±7.2 years for the control group. The lateral rectus angle was significantly more inwardly rotated in the exotropia group than in the control group (1.6±6.3°, −1.4±4.0°, p=0.014). With increasing angle of deviation, the width of the lateral rectus increased (p=0.002). Our results indicate that the lateral rectus angle is significantly more inwardly rotated in patients with exotropia. These findings should contribute to a deeper understanding of the extraocular muscles in patients with this condition. |
| Keywords | exotropia AS-OCT anterior chamber angle to extraocular muscle insertion distance muscle width muscle fiber angle |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-10 |
| Volume | volume79 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 353 |
| End Page | 358 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| JaLCDOI | 10.18926/AMO/69435 |
|---|---|
| FullText URL | 79_5_345.pdf |
| Author | Matsunaga, Nozomu| Egusa, Seira| Aono, Riyo| Tamai, Eiji| Hitusmoto, Yasuo| Katayama, Seiichi| |
| Abstract | Clostridium perfringens is a pathogenic anaerobe that causes gas gangrene and food poisoning. Although autolysin-mediated reorganization of the bacterial cell wall is crucial for cell division, excessive autolysin activity induced by stressors can lead to cell lysis. In C. perfringens, air exposure is a significant stressor that causes cell lysis, and Acp (N-acetylglucosaminidase) is known to be a major autolysin. To further facilitate C. perfringens research, a technology to prevent air-induced cell lysis must be developed. This study investigated the role of Acp in air-induced autolysis and explored potential inhibitors that would prevent cell lysis during experimental procedures. Morphological analyses confirmed that Acp functions as an autolysin in C. perfringens, as acpdeficient strains exhibited filamentous growth. The mutants exhibited negligible autolysis under air-exposure stress, confirming the involvement of Acp in the autolytic process. We also evaluated the effects of various divalent cations on Acp activity in vitro and identified Zn2+ as a potent inhibitor. Brief treatment with a Zn2+- containing buffer induced dose-dependent cell elongation and autolysis inhibition in C. perfringens. These findings demonstrate that simple Zn2+ treatment before experiments stabilizes C. perfringens cells, reducing autolysis under aerobic conditions and facilitating various biological studies, except morphological analyses. |
| Keywords | Clostridium perfringens autolysin zinc air-exposure autolysis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-10 |
| Volume | volume79 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 345 |
| End Page | 352 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| JaLCDOI | 10.18926/AMO/69434 |
|---|---|
| FullText URL | 79_5_339.pdf |
| Author | Hamasaki, Ichiro| Shibata, Kiyo| |
| Abstract | To determine whether passing a pole suture through the sclera at two points provides fixation comparable to that of a sliding noose, we measured the tensile strength of the suture‒sclera interface during simulated traction. In this in vitro study, three suture patterns were evaluated in porcine eyeballs, using 6-0 polyglycolic acid sutures. Patterns A (control), B (second suture pass perpendicular), and C (second suture pass in the same direction) were compared. The tensile strength of each pattern was measured 20 times using a KANON TK300CN, and the results were analyzed using the Kruskal‒Wallis test. Pattern A showed a tensile strength of 2±4 gram-force (gf) (range: 0-12). Pattern B showed 112±38 gf (range: 61-184). Pattern C showed 139±31 gf (range: 97-204). Patterns B and C had significantly higher tensile strengths than Pattern A (p<0.001). Although Pattern C was not significantly different from Pattern B (p=0.363), it exhibited the highest tensile strength. Lifting the suture between the first and second suture passes allows for an adjustable suture length, suggesting that adjustability can be achieved using only the sclera. This scleral adjustment method with a second suture pass offers a durable means of securing extraocular muscles and may represent a valuable addition to adjustable suturing techniques. |
| Keywords | scleral adjustment method adjustable suture technique hang-loose method tensile strength polyglycolic acid sutures |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-10 |
| Volume | volume79 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 339 |
| End Page | 343 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| JaLCDOI | 10.18926/AMO/69433 |
|---|---|
| FullText URL | 79_5_329.pdf |
| Author | Matsubara, Kei| Miyoshi, Kentaroh| Toyooka, Shinichi| |
| Abstract | Primary graft dysfunction (PGD) is one of the major risk factors affecting patients’ short- and long-term survival after lung transplantation. No particular management strategy has been established for PGD; supportive care is the mainstay of PGD treatment. When a supportive strategy fails, the patient may require the introduction of extracorporeal membrane oxygenation (ECMO) as the last-resort measure for severe PGD. A variety of study of ECMO as a PGD treatment was reported and the management of PGD patients developed so far. Early recognition of a patient’s need for ECMO and its prompt initiation are critical to improved outcomes. The use of venovenous-ECMO became the preferred procedure for PGD rather than venoarterial-ECMO. However, the current ECMO strategy has limitations, and using ECMO to manage patients with PGD is not sufficiently effective. Further studies are required to develop this promising technology. |
| Keywords | lung transplantation primary graft dysfunction extracorporeal membrane oxygenation ex vivo lung perfusion |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-10 |
| Volume | volume79 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 329 |
| End Page | 337 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| JaLCDOI | 10.18926/AMO/69432 |
|---|---|
| FullText URL | 79_5_321.pdf |
| Author | Obata, Taisuke| Matsumoto, Kazuyuki| Otsuka, Motoyuki| |
| Abstract | Bile leak occurs in 2-25% of liver transplant, 3-27% of hepatic resection, and 0.1-4% of cholecystectomy cases. The clinical course of bile leak varies depending on the type of surgery that caused the fistula, as well as the type, severity, and timing of bile duct injury. Although infections resulting from bile leak can be life-threatening, the introduction of endoscopic treatment has enabled some patients to avoid reoperation and has reduced the negative impact on quality of life associated with external fistulas for percutaneous drainage. Endoscopic interventions, such as sphincterotomy and stent placement, reduce the pressure gradient between the bile duct and duodenum, facilitating bile drainage through the papilla and promoting the closure of the leak. We reviewed the literature from 2004 to 2024 regarding bile leak following cholecystectomy and liver surgery, examining recommended techniques, timing, and treatment outcomes. In cases of bile leak following cholecystectomy, clinical success was achieved in 72-96% of cases, while success rates for bile leak following liver surgery ranged from 50% to 100%. Although endoscopic treatment is effective, it is not universally applicable, and its limitations must be carefully considered. |
| Keywords | bile leak cholecystectomy hepatic surgery endoscopic retrograde cholangiography bridging stent placement |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-10 |
| Volume | volume79 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 321 |
| End Page | 328 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| FullText URL | fulltext.pdf suppl.pdf |
|---|---|
| Author | Nishimura, Shingo| Inoue, Shota| Sekito, Takanori| Tsuboi, Ichiro| Tokunaga, Moto| Yoshinaga, Kasumi| Maruyama, Yuki| Mitsui, Yosuke| Yamanoi, Tomoaki| Kawada, Tatsushi| Kubota, Risa| Sadahira, Takuya| Tominaga, Yusuke| Iwata, Takehiro| Katayama, Satoshi| Bekku, Kensuke| Edamura, Kohei| Wada, Koichiro| Kobayashi, Yasuyuki| Araki, Motoo| |
| Keywords | living donor kidney transplantation urinary tract infection perioperative desensitization rituximab plasmapheresis body mass index dialysis duration warm ischemic time prophylactic antimicrobials |
| Published Date | 2025-08-28 |
| Publication Title | Journal of Clinical Medicine |
| Volume | volume14 |
| Issue | issue17 |
| Publisher | MDPI AG |
| Start Page | 6102 |
| ISSN | 2077-0383 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 by the authors. |
| File Version | publisher |
| PubMed ID | 40943861 |
| DOI | 10.3390/jcm14176102 |
| Web of Science KeyUT | 001571365300001 |
| Related Url | isVersionOf https://doi.org/10.3390/jcm14176102 |
| FullText URL | fulltext.pdf suppl.docx |
|---|---|
| Author | Kubota, Risa| Sada, Ken-Ei| Tokunaga, Moto| Yoshinaga, Kasumi| Yamanoi, Tomoaki| Kawada, Tatsushi| Tominaga, Yusuke| Sadahira, Takuya| Katayama, Satoshi| Iwata, Takehiro| Nishimura, Shingo| Bekku, Kensuke| Edamura, Kohei| Kobayashi, Tomoko| Nakagawa, Yuki| Ichimaru, Naotsugu| Wada, Koichiro| Araki, Motoo| |
| Keywords | Calcineurin inhibitors Cyclosporine A Kidney transplant Malignant neoplasms Tacrolimus |
| Published Date | 2025-08-26 |
| Publication Title | BMC Nephrology |
| Volume | volume26 |
| Issue | issue1 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 491 |
| ISSN | 1471-2369 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2025. |
| File Version | publisher |
| PubMed ID | 40859155 |
| DOI | 10.1186/s12882-025-04405-8 |
| Web of Science KeyUT | 001559427800001 |
| Related Url | isVersionOf https://doi.org/10.1186/s12882-025-04405-8 |
