result 19462 件
| JaLCDOI | 10.18926/AMO/50405 |
|---|---|
| FullText URL | 67_3_129.pdf |
| Author | Nakatsuka, Atsuko| Wada, Jun| Makino, Hirofumi| |
| Abstract | In recent years, many researchers have emphasized the importance of metabolic syndrome based on its increasing prevalence and its adverse prognosis due to associated chronic vascular complications. Upstream of a cluster of metabolic and vascular disorders is the accumulation of visceral adipose tissue, which plays a central role in the pathophysiology. In the accumulation of adipose tissues, cell cycle regulation is tightly linked to cellular processes such as proliferation, hypertrophy and apoptosis. In addition, various cell cycle abnormalities have also been observed in other tissues, such as kidneys and the cardiovascular system, and they are critically involved in the progression of disease. Here, we discuss cell cycle abnormalities in metabolic syndrome in various tissues. Furthermore, we describe the role of nuclear receptors in cell growth and survival, and glucose and lipid metabolism in the whole body. Therapeutic strategies for modulating various cell cycles in metabolic disorders by targeting nuclear receptors may overcome obesity and its chronic vascular complications in the future. |
| Keywords | nuclear receptor cell cycle metabolic syndrome diabetic nephropathy |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2013-06 |
| Volume | volume67 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 129 |
| End Page | 134 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23804135 |
| Web of Science KeyUT | 000320747900001 |
| Author | Kobayashi, J.| |
|---|---|
| Published Date | 1961-02 |
| Publication Title | 農学研究 |
| Volume | volume48 |
| Issue | issue2 |
| Content Type | Departmental Bulletin Paper |
| Author | Inouye, T.| Oba, K.| Takahashi, R.| |
|---|---|
| Published Date | 1960-01 |
| Publication Title | 農学研究 |
| Volume | volume47 |
| Issue | issue3 |
| Content Type | Departmental Bulletin Paper |
| Author | Wada, S.| Takeda, A.| |
|---|---|
| Published Date | 1959-11 |
| Publication Title | 農学研究 |
| Volume | volume47 |
| Issue | issue1-2 |
| Content Type | Departmental Bulletin Paper |
| Author | Ozawa, J.| Okamoto, A.| Hayashi, T.| |
|---|---|
| Published Date | 1959-11 |
| Publication Title | 農学研究 |
| Volume | volume47 |
| Issue | issue1-2 |
| Content Type | Departmental Bulletin Paper |
| Author | Takahashi, R.| Mochizuki, A.| Hayashi, J.| |
|---|---|
| Published Date | 1959-11 |
| Publication Title | 農学研究 |
| Volume | volume47 |
| Issue | issue1-2 |
| Content Type | Departmental Bulletin Paper |
| Author | Inouye, T.| |
|---|---|
| Published Date | 1959-11 |
| Publication Title | 農学研究 |
| Volume | volume47 |
| Issue | issue1-2 |
| Content Type | Departmental Bulletin Paper |
| Author | Kobayashi, Jun| |
|---|---|
| Published Date | 1953-03-31 |
| Publication Title | 農学研究 |
| Volume | volume41 |
| Issue | issue1 |
| Content Type | Departmental Bulletin Paper |
| FullText URL | AnalyticalMethods_5_11_2854-2859.pdf |
|---|---|
| Author | Inoue, Genki| Kaneta, Takashi| Takayanagi, Toshio| Kakehi, Junichi| Motose, Hiroyasu| Takahashi, Taku| |
| Published Date | 2013-05 |
| Publication Title | Analytical Methods |
| Volume | volume5 |
| Issue | issue11 |
| Publisher | RSC Publishing |
| Start Page | 2854 |
| End Page | 2859 |
| ISSN | 1759-9660 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | ©The Royal Society of Chemistry 2013 |
| File Version | author |
| DOI | 10.1039/C3AY26360F |
| Web of Science KeyUT | 000319004800030 |
| Related Url | isVersionOf https://doi.org/10.1039/C3AY26360F |
| FullText URL | JChromatographyA_1288_149-154.pdf |
|---|---|
| Author | Yamaguchi, Kaori| Takeyasu, Nobuyuki| Kaneta, Takashi| |
| Keywords | Capillary electrophoresis 5 '-Guanosine monophosphate (GMP) G-gel Association constant |
| Published Date | 2013-05-03 |
| Publication Title | Journal of Chromatography A |
| Volume | volume1288 |
| Publisher | Elsevier Science B.V. |
| Start Page | 149 |
| End Page | 154 |
| ISSN | 00219673 |
| NCID | AA10985833 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | (C) 2013 Elsevier B.V. All rights reserved. |
| File Version | author |
| PubMed ID | 23522259 |
| DOI | 10.1016/j.chroma.2013.02.090 |
| Web of Science KeyUT | 000317707900017 |
| Related Url | isVersionOf https://doi.org/10.1016/j.chroma.2013.02.090 |
| Author | Yasuda, Shozo| Hayashi, Jiro| |
|---|---|
| Published Date | 1989 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Biologie, Okayama Universität |
| Volume | volume19 |
| Issue | issue4 |
| Content Type | Departmental Bulletin Paper |
| Author | Nishi, Katsuhisa| |
|---|---|
| Published Date | 1987 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Biologie, Okayama Universität |
| Volume | volume19 |
| Issue | issue3 |
| Content Type | Departmental Bulletin Paper |
| Author | 井上 剛照| |
|---|---|
| Published Date | 2006 |
| Publication Title | |
| Content Type | Book |
| Author | 井上 剛照| |
|---|---|
| Published Date | 2006 |
| Publication Title | |
| Content Type | Book |
| Author | 井上 剛照| |
|---|---|
| Published Date | 2006 |
| Publication Title | |
| Content Type | Book |
| Author | 井上 剛照| |
|---|---|
| Published Date | 2006 |
| Publication Title | |
| Content Type | Book |
| Author | Uchida, Kei| Suzuki, Yukio| |
|---|---|
| Published Date | 1986 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Biologie, Okayama Universität |
| Volume | volume19 |
| Issue | issue2 |
| Content Type | Departmental Bulletin Paper |
| Author | Moritsugu, Masumi| |
|---|---|
| Published Date | 1985 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Biologie, Okayama Universität |
| Volume | volume19 |
| Issue | issue1 |
| Content Type | Departmental Bulletin Paper |
| Author | Seo, Takuro| Maitani, Toshihiko| Hiraoka, Naoko| |
|---|---|
| Published Date | 1985 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Biologie, Okayama Universität |
| Volume | volume19 |
| Issue | issue1 |
| Content Type | Departmental Bulletin Paper |
| Author | Seo, Takuro| |
|---|---|
| Published Date | 1982 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Biologie, Okayama Universität |
| Volume | volume18 |
| Issue | issue2 |
| Content Type | Departmental Bulletin Paper |
