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FullText URL K0007192_abstract_review.pdf K0007192_fulltext.pdf
Author IGAWA, Yusuke|
Published Date 2025-03-25
Content Type Thesis or Dissertation
Grant Number 甲第7192号
Granted Date 2025-03-25
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders © 2024 Igawa, Hamano, Esumi, Takeda, Kajizono, Kikuoka, Kimura and Zamami.
FullText URL K0007189_abstract_review.pdf K0007189_fulltext.pdf K0007189_summary.pdf
Author SUN, HONGMING|
Published Date 2025-03-25
Content Type Thesis or Dissertation
Grant Number 甲第7189号
Granted Date 2025-03-25
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders © The Author(s) 2023
FullText URL K0007188_abstract_review.pdf K0007188_fulltext.pdf K0007188_other fig1.pdf K0007188_other fig2.pdf K0007188_other fig3.pdf K0007188_other fig4.pdf K0007188_other fig5.pdf K0007188_other fig6.pdf K0007188_summary.pdf
Author OTA ELLIOTT RICARDO SATOSHI|
Published Date 2025-03-25
Content Type Thesis or Dissertation
Grant Number 甲第7188号
Granted Date 2025-03-25
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders © 2023 Elsevier B.V.
FullText URL K0007181_abstract_review.pdf K0007181_fulltext.pdf K0007181_summary.pdf
Author TABUCHI, Motoyasu|
Published Date 2025-03-25
Content Type Thesis or Dissertation
Grant Number 甲第7181号
Granted Date 2025-03-25
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders © 2024 The Author(s).
FullText URL fulltext.pdf
Author Takei, Kensuke| Inokuchi, Toshihiro| Hiraoka, Sakiko| Ishiguro, Mikako| Toyosawa, Junki| Aoyama, Yuki| Igawa, Shoko| Takeuchi, Keiko| Yamasaki, Yasushi| Kinugasa, Hideaki| Takahara, Masahiro| Kawano, Seiji| Mitsuhashi, Toshiharu| Otsuka, Motoyuki|
Keywords CD, Crohn's disease LRG, Leucine-rich alpha-2 glycoprotein Fcal, Fecal calprotectin CRP, C-reactive protein ER, Endoscopic remission
Published Date 2025-05-13
Publication Title BMC Gastroenterology
Volume volume25
Issue issue1
Publisher BMC
Start Page 364
ISSN 1471-230X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025.
File Version publisher
PubMed ID 40355822
DOI 10.1186/s12876-025-03880-5
Web of Science KeyUT 001488265300002
Related Url isVersionOf https://doi.org/10.1186/s12876-025-03880-5
FullText URL fulltext.pdf
Author La Rocca, Romain| Kato, Koji| Tsai, Pi-Cheng| Nakajima, Yoshiki| Akita, Fusamichi| Shen, Jian-Ren|
Published Date 2025-05-05
Publication Title Nature Communications
Volume volume16
Issue issue1
Publisher Nature Portfolio
Start Page 4175
ISSN 2041-1723
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 40325014
DOI 10.1038/s41467-025-59512-9
Web of Science KeyUT 001482932500018
Related Url isVersionOf https://doi.org/10.1038/s41467-025-59512-9
Author Kawajiri, Takahiro| Hosoya, Masahiro| Goda, Satoshi| Sato, Eisuke| Suga, Seiji|
Note This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Letters, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.orglett.5c01138.| This fulltext file will be available in Apr. 2026.|
Published Date 2025-04-29
Publication Title Organic Letters
Volume volume27
Issue issue18
Publisher American Chemical Society (ACS)
Start Page 4737
End Page 4741
ISSN 1523-7060
NCID AA11347843
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 American Chemical Society
File Version author
PubMed ID 40302371
DOI 10.1021/acs.orglett.5c01138
Web of Science KeyUT 001479279200001
Related Url isVersionOf https://doi.org/10.1021/acs.orglett.5c01138
FullText URL fulltext.pdf
Author Takatori, S.| Pimon, M.| Pollitt, S.| Bartokos, M.| Beeks, K.| Grueneis, A.| Hiraki, T.| Honma, T.| Hosseini, N.| Leitner, A.| Masuda, T.| Morawetz, I| Nitta, K.| Okai, K.| Riebner, T.| Schaden, F.| Schumm, T.| Sekizawa, O.| Sikorsky, T.| Takahashi, Y.| De Col, Col, L. Toscani| Yamamoto, R.| Yomogida, T.| Yoshimi, A.| Yoshimura, K.|
Keywords solid-state nuclear clock thorium-229 XAFS
Published Date 2025-04-28
Publication Title New Journal of Physics
Volume volume27
Issue issue4
Publisher IOP Publishing
Start Page 043024
ISSN 1367-2630
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
DOI 10.1088/1367-2630/adce22
Web of Science KeyUT 001477975100001
Related Url isVersionOf https://doi.org/10.1088/1367-2630/adce22
Title Alternative The 2023 Incentive Award of the Okayama Medical Association in Cancer Research (2023 Hayashibara Prize and Yamada Prize)
Author Urata, Tomohiro|
Publication Title Journal of Okayama Medical Association
Published Date 2025-04-01
Volume volume137
Issue issue1
Start Page 7
End Page 9
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.137.7
language Japanese
Copyright Holders Copyright (c) 2025 岡山医学会
File Version publisher
DOI 10.4044/joma.137.7
Title Alternative The 2023 Incentive Award of the Okayama Medical Association in Neuroscience (2023 Niimi Prize)
Author Takenoshita, Shintaro|
Publication Title Journal of Okayama Medical Association
Published Date 2025-04-01
Volume volume137
Issue issue1
Start Page 1
End Page 3
ISSN 0030-1558
Related Url isVersionOf https://doi.org/10.4044/joma.137.1
language Japanese
Copyright Holders Copyright (c) 2025 岡山医学会
File Version publisher
DOI 10.4044/joma.137.1
FullText URL fulltext.pdf
Author Sudo, Ryutaro| Miyamoto, Kohta| Ido, Hirofumi|
Keywords Laminated veneer lumber (LVL) Partial compressive load Bearing strength Embedment strength Partial compression perpendicular to grain (PCPG) Adhesive layer
Published Date 2025-04-19
Publication Title Journal of Wood Science
Volume volume71
Issue issue1
Publisher Springer
Start Page 19
ISSN 1435-0211
NCID AA11200007
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025.
File Version publisher
DOI 10.1186/s10086-025-02195-z
Web of Science KeyUT 001469993800002
Related Url isVersionOf https://doi.org/10.1186/s10086-025-02195-z
JaLCDOI 10.18926/AMO/68654
FullText URL 79_2_139.pdf
Author Takeda, Yasushige| Noma, Kazuhiro| Maeda, Naoaki| Mizusawa, Yohei| Matsumoto, Hijiri| Kondo, Yuhei| Kunitomo, Tomoyoshi| Tanoue, Yukinori| Hashimoto, Masashi| Tanabe, Shunsuke| Fujiwara, Toshiyoshi|
Abstract In thoracic esophageal cancer, lymph node dissection around the recurrent laryngeal nerve is crucial but poses a risk of nerve palsy, affecting postoperative quality of life. In cases with an aberrant right subclavian artery (ARSA), the right recurrent laryngeal nerve is absent, and the non-recurrent inferior laryngeal nerve (NRILN) enters the larynx directly from the vagus nerve in the cervical region. Identifying the course of the NRILN is vital to avoid injury. A case of esophageal cancer with an ARSA, in which the course of the NRILN was preserved using the Nerve Integrity Monitoring (NIM) system during surgery, is described.
Keywords esophageal cancer intraoperative nerve monitoring aberrant right subclavian artery non-recurrent inferior laryngeal nerve thoracoscopic esophagectomy
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2025-04
Volume volume79
Issue issue2
Publisher Okayama University Medical School
Start Page 139
End Page 144
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/68653
FullText URL 79_2_135.pdf
Author Fujita, Yasufumi| Shimizu, Shuji| Mohri, Makoto|
Abstract Cardiac calcified amorphous tumor (CAT) is a rare, benign non-neoplastic mass of the heart that is sometimes found due to embolic events. Most cases of CAT are treated with surgical removal to prevent future embolic events. However, the treatment strategy for CAT complicated by atrial fibrillation has remained to be determined. Here we report a case of left ventricular CAT complicated by paroxysmal atrial fibrillation (PAF) that was successfully treated with surgical removal and pulmonary vein isolation. Pulmonary vein isolation can be a simple and effective procedure for PAF, even during surgical removal of CAT.
Keywords calcified amorphous tumor surgical removal embolic stroke paroxysmal atrial fibrillation pulmonary vein isolation
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2025-04
Volume volume79
Issue issue2
Publisher Okayama University Medical School
Start Page 135
End Page 138
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/68652
FullText URL 79_2_129.pdf
Author Tsuji, Akihiro| Shiode, Yusuke| Kimura, Shuhei| Hosokawa, Mio| Matoba, Ryo| Morita, Tetsuro| Takahashi, Kosuke| Morizane, Yuki|
Abstract A 66-year-old woman presented with significant anterior capsule contraction and intraocular lens dislocation in both eyes 4 months after cataract surgery. Postoperative examinations such as fluorescein angiography, Goldmann perimetry, and electroretinography revealed retinitis pigmentosa (RP). Patients with significant anterior capsule contraction after cataract surgery should be closely examined because RP may be a contributing factor.
Keywords retinitis pigmentosa intraocular lens anterior capsule contraction
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2025-04
Volume volume79
Issue issue2
Publisher Okayama University Medical School
Start Page 129
End Page 134
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/68651
FullText URL 79_2_123.pdf
Author Akatsuka, Riku| Kimura, Shuhei| Matoba, Ryo| Morizane Hosokawa, Mio| Shiode, Yusuke| Morita, Tetsuro| Doi, Shinichiro| Morizane, Yuki|
Abstract A 78-year-old woman presented with sudden vision loss and central scotoma. Visual acuity in the right eye was 20/222, with submacular hemorrhage (SMH) and Henle fiber layer hemorrhage (HFLh) due to retinal arterial macroaneurysm (RAM) rupture. She underwent SMH displacement, including cataract surgery, vitrectomy, intravitreal injection of tissue-plasminogen activator, and air tamponade. Three months postoperatively the SMH and HFLh had disappeared and visual acuity had improved to 20/200. Six months postoperatively, a macular hole had developed. We performed an inverted internal limiting membrane flap and gas tamponade. Ten months later, the hole had closed and visual acuity had improved to 20/100.
Keywords submacular hemorrhage Henle fiber layer hemorrhage retinal arterial macroaneurysm rupture macular hole inverted internal limiting membrane flap technique
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2025-04
Volume volume79
Issue issue2
Publisher Okayama University Medical School
Start Page 123
End Page 127
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/68650
FullText URL 79_2_117.pdf
Author Gautam, Abhishek| Kenawadekar, Rahul| Hattiholi, Virupaxi| Maste, Praful Suresh|
Abstract Neural tube defects are common congenital anomalies, typically presenting early due to visible swelling and/or neurological deficits. Rarely, cystic swellings are neglected until adulthood, with only 14 cases of malignancy developing in an untreated meningomyelocele reported to date. We describe the case details of a 26-year-old Indian woman with this rare complication. Magnetic resonance imaging revealed a low-lying spinal cord with spinal dysraphism, cord herniation, and a cystic lesion. The biopsy confirmed a well-differentiated squamous cell carcinoma. Malignant transformation in an untreated myelomeningocele is rare, with chronic irritation and infection as proposed causes. Early biopsy and treatment are crucial for its management.
Keywords squamous cell carcinoma meningomyelocele occult spinal dysraphism
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2025-04
Volume volume79
Issue issue2
Publisher Okayama University Medical School
Start Page 117
End Page 121
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/68649
FullText URL 79_2_109.pdf
Author Awai, Kyoko| Nakatsuka, Mikiya|
Abstract The status of postpartum depression was elucidated herein with the use of the Edinburgh Postnatal Depression Scale (EPDS) in women in Shikoku, Japan who became pregnant and gave birth after undergoing infertility treatment, including assisted reproductive technology (ART). The assessment was performed during their children’s 4-month health examination. The relationships between postpartum depression and the mothers’ background factors and scores on the Big Five personality traits scale were also examined. Of the Big Five personality traits, the scores for neuroticism were significantly higher in the ART group (n=71) than in the general infertility treatment (n=118) and natural pregnancy (n=872) groups. No significant differences in EPDS scores were seen among these three groups. A logistic regression analysis showed that neuroticism was associated with an EPDS score ≧9 points, (which is suggestive of postpartum depression, ) in all groups. Moreover, although a long-standing marriage had an inhibitory effect on postpartum depression in the natural pregnancy group, no such trend was seen in the ART group, which included many women with long-standing marriages. Particularly for women who become pregnant by ART, an individualized response that pays close attention to the woman’s personality traits is needed.
Keywords infertility treatment assisted reproductive technology postpartum postpartum depression personality trait
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-04
Volume volume79
Issue issue2
Publisher Okayama University Medical School
Start Page 109
End Page 116
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/68648
FullText URL 79_2_101.pdf
Author Isozaki, Hiroshi| Matsumoto, Sasau| Takama, Takehiro| Isozaki, Yuka|
Abstract To evaluate the effectiveness of postoperative irradiation (POI) for patients with cN0 early breast cancer, we retrospectively analyzed the cases of 650 consecutive breast cancer patients who underwent sentinel lymph node (SLN)-guided surgery (2005-2022) at our hospital. In this cohort, 53% (278/521) of the patients who underwent breast conservative surgery (BCS) and 96% (124/129) of those treated with mastectomy did not receive POI. The patients who underwent BCS were treated with POI using opposing tangential field irradiation. A false negative (FN) SLN was retrospectively defined as a negative metastasis in SLN plus positive recurrence in the axillary lymph nodes. Recurrence was detected in 83 patients. A logistic regression analysis revealed that the nuclear grade (odds ratio [OR] 1.69), POI (OR 0.41), and postoperative hormone therapy (OR 0.40) were each significantly related to recurrence. The 26.1% (12/46) FN rate of the non-POI patients decreased to 5.8% (1/17) compared to those treated with POI. The rate of axillary recurrence was significantly lower in the POI group (0.4%) versus the non-POI group (2.7%) (p=0.0355). The rate of locoregional recurrence was also significantly lower in the POI group (2.0%) versus the non-POI group (13.4%) (p<0.0001). No significant difference was observed in the rate of distant recurrence between the POI (4.0%) and non-POI (3.3%) (p=0.831) groups. These results indicated that the postoperative opposing tangential field irradiation of conserved breast tissue inhibited recurrence in the axillary lymph nodes.
Keywords breast cancer postoperative irradiation radiation therapy sentinel lymph nodes recurrence
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-04
Volume volume79
Issue issue2
Publisher Okayama University Medical School
Start Page 101
End Page 107
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/68647
FullText URL 79_2_093.pdf
Author Tsuchie, Rina| Fukuda, Mari| Tsumura, Hideki| Kinuta, Minako| Hisamatsu, Takashi| Kanda, Hideyuki|
Abstract School teachers are subject to both physical and mental health problems. We examined cross-sectional relationships between work engagement and major health outcomes among junior and senior high school teachers in Japan via a nationwide survey in 2019-2020. A total of 3,160 respondents were included in the analyses (19.9% response rate). Work engagement was assessed with the Utrecht Work Engagement Scale-9 (UWES-9), and we thus divided the teachers into quartiles according to their UWES-9 scores. Based on validated questionnaires, we assessed insomnia, psychological distress, and neck pain as health outcomes. A binomial logistic regression adjusted for age, gender, school type, teacher’s roles, involvement in club activities, division of duties, employment status, and whether they lived with family demonstrated that the teachers with lower UWES-9 scores had higher burdens of insomnia, psychological distress, and neck pain (odds ratios [95% confidence intervals] in 4th vs. 1st quartile, 2.92 (2.34-3.65), 3.70 (2.81-4.88), and 2.12 (1.68-2.68), respectively; all trend p<0.001). There were no significant differences in these associations between full-time and part-time teachers. Our findings indicate that low work engagement may contribute to physical and mental health issues among junior and senior high school teachers, thus providing insights for preventing health problems in this profession.
Keywords work engagement school teachers insomnia psychological distress neck pain
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-04
Volume volume79
Issue issue2
Publisher Okayama University Medical School
Start Page 93
End Page 100
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/68646
FullText URL 79_2_081.pdf
Author Kawada, Tatsushi| Kobayashi, Yasuyuki| Tsugawa, Takuji| Tsuboi, Kazuma| Katayama, Satoshi| Iwata, Takehiro| Bekku, Kensuke| Kobayashi, Tomoko| Edamura, Kohei| Ebara, Shin| Araki, Motoo|
Abstract We retrospectively evaluated the oncologic outcomes of paclitaxel, cisplatin, and gemcitabine (PCG) with those of gemcitabine and cisplatin (GC) as neoadjuvant chemotherapy in muscle-invasive bladder cancer (MIBC) patients. The primary outcome was efficacy: pathological complete response (pCR), ypT0N0; and pathological objective response (pOR), ypT0N0, ≤ ypT1N0, or ypT0N1. Secondary outcomes included overall survival (OS), recurrence-free survival (RFS), predictive factors for pOR, OS, and RFS, and hematologic adverse events (AEs). Among 113 patients treated (PCG, n=28; GC, n=85), similar pOR and pCR rates were achieved by the groups (pOR: PCG, 57.1% vs. GC, 49. 4%; p=0.52; pCR: PCG, 39.3% vs. GC, 29.4%; p=0.36). No significant differences were observed in OS (p=1.0) or RFS (p=0.20). Multivariate logistic regression analysis showed that hydronephrosis (odds ratio [OR] 0.32, 95%CI: 0.11-0.92) and clinical node-positive status (cN+) (OR 0.22, 95%CI: 0.050-0.99) were significantly associated with a decreased probability of pOR. On multivariate Cox regression analyses, pOR achievement was associated with improved OS (hazard ratio [HR] 0.23, 95%CI: 0.10-0.56) and RFS (HR 0.30, 95%CI: 0.13-0.67). There were no significant between-group differences in the incidence of grade ≥ 3 hematologic AEs or dose-reduction required, but the PCG group had a higher incidence of grade 4 neutropenia.
Keywords urothelial carcinoma paclitaxel cisplatin gemcitabine neoadjuvant
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2025-04
Volume volume79
Issue issue2
Publisher Okayama University Medical School
Start Page 81
End Page 92
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True