result 693 件
FullText URL | fulltext.pdf suppl1.docx suppl2.tif suppl3.tif suppl4.tif |
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Author | Matsuda, Shinji| Yumoto, Hiromichi| Komatsu, Yasutaka| Dewake, Nanae| Iwata, Takanori| Nagano, Takatoshi| Morozumi, Toshiya| Goto, Ryoma| Kato, Satsuki| Yamashita, Motozo| Hayashi, Joichiro| Sekino, Satoshi| Yamashita, Akiko| Yamashita, Keiko| Yoshimura, Atsutoshi| Sugaya, Tsutomu| Takashiba, Shogo| Taguchi, Yoichiro| Nemoto, Eiji| Shintani, Tomoaki| Miyagawa, Tsuyoshi| Nishi, Hiromi| Mizuno, Noriyoshi| Numabe, Yukihiro| Kawaguchi, Hiroyuki| |
Keywords | Periodontal diseases Masticatory system Nonsurgical periodontal debridement |
Published Date | 2025-07-04 |
Publication Title | BMC Oral Health |
Volume | volume25 |
Issue | issue1 |
Publisher | Springer Science and Business Media LLC |
Start Page | 1094 |
ISSN | 1472-6831 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2025. |
File Version | publisher |
PubMed ID | 40616032 |
DOI | 10.1186/s12903-025-06456-7 |
Web of Science KeyUT | 001523058100003 |
Related Url | isVersionOf https://doi.org/10.1186/s12903-025-06456-7 |
JaLCDOI | 10.18926/AMO/69151 |
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FullText URL | 79_4_261.pdf |
Author | Hirata, Yuichi| Sugahara, Chiaki| Sasada, Susumu| Miyake, Hayato| Nagase, Takayuki| Yasuhara, Takao| Tanaka, Shota| |
Abstract | Cervical spondylotic myelopathy (CSM) and ossification of the posterior longitudinal ligament (OPLL) increase the likelihood of spinal cord injury without radiographic evidence of trauma (SCIWORET). Opinions regarding the optimal timing for surgery in such cases vary, however. We retrospectively investigated the demographics and outcomes of patients with SCIWORET who underwent surgery shortly after experiencing rapid neurological deterioration, and we matched patients who underwent standby surgery for CSM or OPLL. Although the optimal timing of surgery for SCIWORET remains unclear, our findings suggest that early stage surgery for SCIWORET may yield favorable neurological improvements. |
Keywords | spinal trauma SCIWORET timing of surgery cervical spondylotic myelopathy ossification of the posterior longitudinal ligament |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2025-08 |
Volume | volume79 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 261 |
End Page | 267 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
FullText URL | fulltext.pdf |
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Author | Makino, Takuma| Nishikori, Asami| Sato, Yasuharu| Naoi, Yuto| Matsumoto, Junya| Fujimoto, Shohei| Ando, Mizuo| |
Keywords | ear-infrared photoimmunotherapy (NIR-PIT) Epidermal growth factor receptor (EGFR) Cylindrical diffuser Puncture interval Base of tongue cancer |
Published Date | 2025-08 |
Publication Title | Photodiagnosis and Photodynamic Therapy |
Volume | volume54 |
Publisher | Elsevier BV |
Start Page | 104719 |
ISSN | 1572-1000 |
NCID | AA11969923 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 The Author(s). |
File Version | publisher |
PubMed ID | 40659300 |
DOI | 10.1016/j.pdpdt.2025.104719 |
Related Url | isVersionOf https://doi.org/10.1016/j.pdpdt.2025.104719 |
FullText URL | fulltext.pdf suppl.pdf |
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Author | Obata, Taisuke| Matsumoto, Kazuyuki| Harada, Kei| Hattori, Nao| Sato, Ryosuke| Matsumi, Akihiro| Miyamoto, Kazuya| Terasawa, Hiroyuki| Fujii, Yuki| Uchida, Daisuke| Horiguchi, Shigeru| Tsutsumi, Koichiro| Otsuka, Motoyuki| |
Keywords | bile leak endoscopic treatment bridging |
Published Date | 2025-05-13 |
Publication Title | Journal of Clinical Medicine |
Volume | volume14 |
Issue | issue10 |
Publisher | MDPI AG |
Start Page | 3381 |
ISSN | 2077-0383 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 by the authors. |
File Version | publisher |
PubMed ID | 40429376 |
DOI | 10.3390/jcm14103381 |
Web of Science KeyUT | 001497497400001 |
Related Url | isVersionOf https://doi.org/10.3390/jcm14103381 |
FullText URL | fulltext.pdf |
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Author | Quoc Doan, Tuan| Tien Dinh, Tai| K. Matsumoto, Tetsuya| Dinh, Dien| Miki, Naoko| Hirobe, Muneto| Thi Nguyen, Hoai| |
Keywords | Acacia crassicarpa Essential oil Tridecanal (E)-Caryophyllene |
Published Date | 2025-05-27 |
Publication Title | Bulletin of the Chemical Society of Ethiopia |
Volume | volume39 |
Issue | issue8 |
Publisher | African Journals Online (AJOL) |
Start Page | 1653 |
End Page | 1660 |
ISSN | 1726-801X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 Chemical Society of Ethiopia and The Authors |
File Version | publisher |
DOI | 10.4314/bcse.v39i8.15 |
Web of Science KeyUT | 001513350700015 |
Related Url | isVersionOf https://doi.org/10.4314/bcse.v39i8.15 |
FullText URL | K0007252_abstract_review.pdf K0007252_fulltext.pdf K0007252_other1.pdf K0007252_other2.pdf K0007252_summary.pdf |
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Author | MATSUMOTO, Toshiki| |
Published Date | 2025-03-25 |
Content Type | Thesis or Dissertation |
Grant Number | 甲第7252号 |
Granted Date | 2025-03-25 |
Thesis Type | Doctor of Philosophy in Dental Science |
Grantor | 岡山大学 |
language | Japanese |
FullText URL | K0007239_abstract_review.pdf K0007239_summary.pdf |
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Author | SATO, Ryosuke| |
Published Date | 2025-03-25 |
Content Type | Thesis or Dissertation |
Grant Number | 甲第7239号 |
Granted Date | 2025-03-25 |
Thesis Type | Doctor of Philosophy in Medical Science |
Grantor | 岡山大学 |
language | English |
Copyright Holders | © 2024 by the American Society for Gastrointestinal Endoscopy |
FullText URL | K0007234_abstract_review.pdf K0007234_summary.pdf |
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Author | HASHIMOTO, Shingo| |
Published Date | 2025-03-25 |
Content Type | Thesis or Dissertation |
Grant Number | 甲第7234号 |
Granted Date | 2025-03-25 |
Thesis Type | Doctor of Philosophy in Medical Science |
Grantor | 岡山大学 |
language | English |
Copyright Holders | © 2024 The Society for Biotechnology, Japan. |
FullText URL | K0007223_abstract_review.pdf K0007223_fulltext.pdf |
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Author | TAKAHASHI, Yukari| |
Published Date | 2025-03-25 |
Content Type | Thesis or Dissertation |
Grant Number | 甲第7223号 |
Granted Date | 2025-03-25 |
Thesis Type | Doctor of Philosophy in Medical Science |
Grantor | 岡山大学 |
language | English |
Copyright Holders | © 2025 Authors |
FullText URL | K0007220_abstract_review.pdf K0007220_fulltext.pdf K0007220_summary.pdf |
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Author | ZHAO, KUN| |
Published Date | 2025-03-25 |
Content Type | Thesis or Dissertation |
Grant Number | 甲第7220号 |
Granted Date | 2025-03-25 |
Thesis Type | Doctor of Philosophy in Medical Science |
Grantor | 岡山大学 |
language | English |
Copyright Holders | © The Author(s) 2025. |
FullText URL | K0007204_abstract_review.pdf K0007204_fulltext.pdf K0007204_summary.pdf |
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Author | TSUBOI, Nobushige| |
Published Date | 2025-03-25 |
Content Type | Thesis or Dissertation |
Grant Number | 甲第7204号 |
Granted Date | 2025-03-25 |
Thesis Type | Doctor of Philosophy in Medical Science |
Grantor | 岡山大学 |
language | English |
Copyright Holders | © 2024 The Author(s). |
JaLCDOI | 10.18926/AMO/68724 |
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FullText URL | 79_3_167.pdf |
Author | Kanaji, Nobuhiro| Nishii, Kazuya| Tsubata, Yukari| Nakao, Mika| Okuno, Takae| Okawa, Sachi| Takata, Kenji| Kodani, Masahiro| Yamasaki, Masahiro| Fujitaka, Kazunori| Kubota, Tetsuya| Inoue, Masaaki| Watanabe, Naoki| Hotta, Katsuyuki| CS-Lung-003 Investigator| |
Abstract | This prospective observational study investigated the clinical status of patients with advanced non-small cell lung cancer (NSCLC) treated with cytotoxic chemotherapy+an immune checkpoint inhibitor (chemo + IO) as first-line treatment in a real-world setting. The cases of 98 patients treated with chemo + IO were prospectively collected and analyzed for effectiveness and safety. The response rate to chemo + IO was 46.9%, and the disease control rate was 76.5%. The median progression-free survival and overall survival (OS) in the total population were 5.2 and 22.3 months, respectively. The patients positive for PD-L1 (≥ 1%) showed significantly longer OS than the negative group (<1%) (median 26.7 vs. 18.7 months, p=0.04). Pre-existing interstitial lung disease (ILD) was associated with shorter OS than the absence of ILD (median 9.0 vs. 22.6 months, p<0.01). Immunerelated adverse events (irAEs) were observed in 28 patients (28.6%). The most frequent irAE was ILD (n=11); Grade 1 (n=1 patient), G2 (n=5), G3 (n=4), and only a single patient with a G5 irAE. In this CS-Lung-003 study, first-line chemo + IO in a real-world setting showed good effectiveness, comparable to that observed in international clinical trials. In real-world practice, chemo + IO is a promising and steadfast strategy. |
Keywords | non-small cell lung cancer real-world first-line immune checkpoint inhibitor combined immunotherapy |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2025-06 |
Volume | volume79 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 167 |
End Page | 176 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
JaLCDOI | 10.18926/AMO/68722 |
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FullText URL | 79_3_147.pdf |
Author | Watanabe, Haruki| Matsumoto, Yoshinori| Wada, Jun| |
Abstract | Pathogens or their components can induce long-lasting changes in the behavior of innate immune cells, a process analogous to “training” for future threats or environmental adaptation. However, such training can sometimes have unintended consequences, such as the development of autoimmunity. Systemic lupus erythematosus (SLE) is a chronic and heterogeneous autoimmune disease characterized by the production of autoantibodies and progressive organ damage. Innate immunity plays a central role in its pathogenesis, contributing through impaired clearance of apoptotic cells, excessive type I interferon production, and dysregulated formation of neutrophil extracellular traps. Recent studies have revealed that metabolites and nucleic acids derived from mitochondria, a crucial energy production site, directly regulate type I interferon and anti-inflammatory cytokine production. These insights have fueled interest in targeting metabolic pathways as a novel therapeutic approach for SLE, offering promise for improving long-term patient outcomes. |
Keywords | systemic lupus erythematosus interferon tricarboxylic acid cycle innate immune memory trained immunity |
Amo Type | Review |
Publication Title | Acta Medica Okayama |
Published Date | 2025-06 |
Volume | volume79 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 147 |
End Page | 155 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
Author | Takeda, Tatsuaki| Matsumoto, Jun| Sakai, Tomonori| Iwata, Naohiro| Hamano, Hirofumi| Koyama, Toshihiro| Ariyoshi, Noritaka| Zamami, Yoshito| |
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Keywords | adverse event breast cancer pertuzumab trastuzumab VigiBase |
Note | This is the peer reviewed version of the following article: [Takeda T, Matsumoto J, Sakai T, et al. Comprehensive analysis of adverse event profile changes with pertuzumab addition to trastuzumab-based breast cancer therapy: Disproportionality analysis using VigiBase. Br J Clin Pharmacol. 2025; 1-13. doi:10.1002/bcp.70094], which has been published in final form at [https://doi.org/10.1002/bcp.70094]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| This fulltext file will be available in May. 2026.| |
Published Date | 2025-05-08 |
Publication Title | British Journal of Clinical Pharmacology |
Publisher | Wiley |
ISSN | 0306-5251 |
NCID | AA00574388 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 British Pharmacological Society. |
File Version | author |
PubMed ID | 40344285 |
DOI | 10.1002/bcp.70094 |
Web of Science KeyUT | 001483932800001 |
Related Url | isVersionOf https://doi.org/10.1002/bcp.70094 |
FullText URL | fulltext.pdf |
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Author | Maruo, Yukinori| Kuwahara, Miho| Yoshihara, Kumiko| Irie, Masao| Nagaoka, Noriyuki| Yoshizane, Mai| Matsumoto, Takuya| Akiyama, Kentaro| |
Keywords | silane coupling bond strength ceramic feldspathic lithium polymer-infiltrated ceramic CAD/CAM |
Published Date | 2025-04-27 |
Publication Title | Materials |
Volume | volume18 |
Issue | issue9 |
Publisher | MDPI |
Start Page | 1983 |
ISSN | 1996-1944 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 by the authors. |
File Version | publisher |
PubMed ID | 40363487 |
DOI | 10.3390/ma18091983 |
Web of Science KeyUT | 001486402200001 |
Related Url | isVersionOf https://doi.org/10.3390/ma18091983 |
JaLCDOI | 10.18926/AMO/68654 |
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FullText URL | 79_2_139.pdf |
Author | Takeda, Yasushige| Noma, Kazuhiro| Maeda, Naoaki| Mizusawa, Yohei| Matsumoto, Hijiri| Kondo, Yuhei| Kunitomo, Tomoyoshi| Tanoue, Yukinori| Hashimoto, Masashi| Tanabe, Shunsuke| Fujiwara, Toshiyoshi| |
Abstract | In thoracic esophageal cancer, lymph node dissection around the recurrent laryngeal nerve is crucial but poses a risk of nerve palsy, affecting postoperative quality of life. In cases with an aberrant right subclavian artery (ARSA), the right recurrent laryngeal nerve is absent, and the non-recurrent inferior laryngeal nerve (NRILN) enters the larynx directly from the vagus nerve in the cervical region. Identifying the course of the NRILN is vital to avoid injury. A case of esophageal cancer with an ARSA, in which the course of the NRILN was preserved using the Nerve Integrity Monitoring (NIM) system during surgery, is described. |
Keywords | esophageal cancer intraoperative nerve monitoring aberrant right subclavian artery non-recurrent inferior laryngeal nerve thoracoscopic esophagectomy |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2025-04 |
Volume | volume79 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 139 |
End Page | 144 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 40302287 |
Web of Science KeyUT | 001485501900001 |
JaLCDOI | 10.18926/AMO/68648 |
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FullText URL | 79_2_101.pdf |
Author | Isozaki, Hiroshi| Matsumoto, Sasau| Takama, Takehiro| Isozaki, Yuka| |
Abstract | To evaluate the effectiveness of postoperative irradiation (POI) for patients with cN0 early breast cancer, we retrospectively analyzed the cases of 650 consecutive breast cancer patients who underwent sentinel lymph node (SLN)-guided surgery (2005-2022) at our hospital. In this cohort, 53% (278/521) of the patients who underwent breast conservative surgery (BCS) and 96% (124/129) of those treated with mastectomy did not receive POI. The patients who underwent BCS were treated with POI using opposing tangential field irradiation. A false negative (FN) SLN was retrospectively defined as a negative metastasis in SLN plus positive recurrence in the axillary lymph nodes. Recurrence was detected in 83 patients. A logistic regression analysis revealed that the nuclear grade (odds ratio [OR] 1.69), POI (OR 0.41), and postoperative hormone therapy (OR 0.40) were each significantly related to recurrence. The 26.1% (12/46) FN rate of the non-POI patients decreased to 5.8% (1/17) compared to those treated with POI. The rate of axillary recurrence was significantly lower in the POI group (0.4%) versus the non-POI group (2.7%) (p=0.0355). The rate of locoregional recurrence was also significantly lower in the POI group (2.0%) versus the non-POI group (13.4%) (p<0.0001). No significant difference was observed in the rate of distant recurrence between the POI (4.0%) and non-POI (3.3%) (p=0.831) groups. These results indicated that the postoperative opposing tangential field irradiation of conserved breast tissue inhibited recurrence in the axillary lymph nodes. |
Keywords | breast cancer postoperative irradiation radiation therapy sentinel lymph nodes recurrence |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2025-04 |
Volume | volume79 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 101 |
End Page | 107 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 40302281 |
Web of Science KeyUT | 001485544200005 |
FullText URL | fulltext.pdf |
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Author | Fujii, Yuki| Matsumoto, Kazuyuki| Matsumi, Akihiro| Miyamoto, Kazuya| Uchida, Daisuke| Horiguchi, Shigeru| Tsutsumi, Koichiro| Mitsuhashi, Toshiharu| Otsuka, Motoyuki| |
Keywords | adverse events balloon-assisted ERCP benzodiazepine sedation |
Published Date | 2025-03-27 |
Publication Title | Journal of Clinical Medicine |
Volume | volume14 |
Issue | issue7 |
Publisher | MDPI |
Start Page | 2287 |
ISSN | 2077-0383 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 by the authors. |
File Version | publisher |
PubMed ID | 40217737 |
DOI | 10.3390/jcm14072287 |
Web of Science KeyUT | 001463583200001 |
Related Url | isVersionOf https://doi.org/10.3390/jcm14072287 |
FullText URL | fulltext.pdf |
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Author | Matsumoto, Kazuya| Matsumoto, Yoshinori| Wada, Jun| |
Keywords | PARylation cancer post-transcriptional regulation ubiquitylation immune system |
Published Date | 2025-03-11 |
Publication Title | Frontiers in Immunology |
Volume | volume16 |
Publisher | Frontiers Media |
Start Page | 1537615 |
ISSN | 1664-3224 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2025 Matsumoto, Matsumoto and Wada. |
File Version | publisher |
PubMed ID | 40134437 |
DOI | 10.3389/fimmu.2025.1537615 |
Web of Science KeyUT | 001450818200001 |
Related Url | isVersionOf https://doi.org/10.3389/fimmu.2025.1537615 |
FullText URL | fulltext.pdf |
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Author | Fujii, Yuki| Matsumoto, Kazuyuki| Ochi, Kiyoaki| Himei, Hitomi| Sakakihara, Ichiro| Ueta, Eijiro| Toyokawa, Tatsuya| Harada, Ryo| Ogawa, Taiji| Tomoda, Takeshi| Kato, Hironari| Sato, Ryosuke| Obata, Taisuke| Matsumi, Akihiro| Miyamoto, Kazuya| Uchida, Daisuke| Horiguchi, Shigeru| Tsutsumi, Koichiro| Otsuka, Motoyuki| |
Keywords | clipping closure delayed bleeding endoscopic papillectomy |
Published Date | 2025 |
Publication Title | Therapeutic Advances in Gastroenterology |
Volume | volume18 |
Publisher | SAGE Publications |
ISSN | 1756-2848 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s), 2025. |
File Version | publisher |
PubMed ID | 40104325 |
DOI | 10.1177/17562848251326450 |
Web of Science KeyUT | 001447404800001 |
Related Url | isVersionOf https://doi.org/10.1177/17562848251326450 |