result 4044 件
JaLCDOI | 10.18926/AMO/60364 |
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FullText URL | 74_4_275.pdf |
Author | Muro, Taiko| Nakamura, Shinichiro| Takaki, Akinobu| Onishi, Hideki| Wada, Nozomu| Yasunaka, Tetsuya| Uchida, Daisuke| Oyama, Atsushi| Adachi, Takuya| Shiraha, Hidenori| Okada, Hiroyuki| |
Abstract | Radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) is a promising method for controlling tumors, although it does not entirely eliminate recurrence. Oxidative stress is associated with the progression of hepatocarcinogenesis, while also acting as an anticancer response. The objective of the present study was to investigate the factors influencing post-RFA outcomes. We recruited 235 newly diagnosed HCC patients who received RFA for single tumors. The patients with recurrence were sub-grouped into early and segmental recurrence groups. The characteristics of the sub-grouped patients were evaluated, including by measuring oxidative stress marker reactive oxygen metabolites and antioxidant marker OXY-adsorbent tests. The factors associated with poor survival were a high Child-Pugh score and early recurrence within 2 years in the same segment. The patients who experienced recurrence within 2 years in the same segment showed a larger tumor diameter than did others. According to a multivariate analysis, the OXY values were also significantly low in these patients. In conclusion, maintaining the antioxidant reservoir function with a high OXY value might be necessary to prevent early recurrence within the RFA-treated segment. |
Keywords | oxidative stress hepatocellular carcinoma recurrence, radiofrequency ablation |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2020-08 |
Volume | volume74 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 275 |
End Page | 283 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 32843758 |
Web of Science KeyUT | 000562508700002 |
NAID | 120006880203 |
JaLCDOI | 10.18926/AMO/60363 |
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FullText URL | 74_4_265.pdf |
Author | Inokuchi, Toshihiro| Hiraoka, Sakiko| Yasutomi, Eriko| Oka, Shohei| Yamasaki, Yasushi| Kinugasa, Hideaki| Takahar, Masahiro| Kawano, Seiji| Harada, Keita| Okada, Hiroyuki| Kato, Jun| |
Abstract | Determining factors that predict a favorable disease course without anti-tumor necrosis factor (TNF) agents would help establish a more cost-effective strategy for Crohn’s disease (CD). A retrospective chart review was performed for CD patients with disease durations > 10 years who had not received anti-TNF agents as first-line therapy. Patients were divided into 2 groups: those who received neither anti-TNF agents nor bowel resection (G1), and those who had received an anti-TNF agent and/or bowel resection (G2). The patient backgrounds, therapies and clinical courses were compared between the groups. A total of 62 CD patients met the inclusion criteria (males: 71%; median duration of follow-up: 19 years). Six patients were included in G1; they were significantly less likely to have upper gastrointestinal lesions than G2 (p=0.007). A multivariate analysis revealed that the significant factors for avoidance of bowel resection without anti-TNF treatment were non-stricturing and non-penetrating behaviors, and absence of upper gastrointestinal lesions at the diagnosis (hazard ratios 0.41 and 0.52; p=0.004 and 0.04, respectively). In consideration of the long treatment course of CD, patients with non-stricturing and non-penetrating behaviors and no upper gastrointestinal lesions should not be treated with anti-TNF agents as first-line therapy. |
Keywords | Crohn’s disease anti-TNF agent upper gastrointestinal lesion bamboo joint-like appearance |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2020-08 |
Volume | volume74 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 265 |
End Page | 274 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 32843757 |
Web of Science KeyUT | 000562508700001 |
NAID | 120006880202 |
FullText URL | fulltext.pdf |
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Author | Sugimoto, Seiichiro| Soh, Junichi| Suzawa, Ken| Miyoshi, Kentaroh| Otani, Shinji| Yamamoto, Hiromasa| Okazaki, Mikio| Yamane, Masaomi| Oto, Takahiro| Kanazawa, Susumu| Kiura, Katsuyuki| Toyooka, Shinichi| |
Keywords | Lung cancer Aspergillosis Surgery Radiation Chemotherapy |
Note | This is a post-peer-review, pre-copyedit version of an article published in Surgery Today. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00595-020-01960-5.| |
Published Date | 2020-01-21 |
Publication Title | Surgery Today |
Volume | volume50 |
Issue | issue8 |
Publisher | Springer |
Start Page | 863 |
End Page | 871 |
ISSN | 0941-1291 |
NCID | AA10824685 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | author |
PubMed ID | 31965262 |
DOI | 10.1007/s00595-020-01960-5 |
Web of Science KeyUT | 000550244700010 |
Related Url | isVersionOf https://doi.org/10.1007/s00595-020-01960-5 |
FullText URL | JEM_fulltext.pdf |
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Author | Okayasu, Mitsuhiro| Ogawa, Tsukasa| |
Keywords | Piezoelectric ceramic lead zirconate titanate ceramic electrical power generation domain switching cyclic loading |
Note | This is a post-peer-review, pre-copyedit version of an article published in Journal of Electronic Materials. The final authenticated version is available online at: http://dx.doi.org/10.1007/s11664-020-08303-7. This fulltext is available in Jul. 2021.| |
Published Date | 2020-07-08 |
Publication Title | Journal of Electronic Materials |
Publisher | Springer |
ISSN | 0361-5235 |
NCID | AA00697093 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | author |
DOI | 10.1007/s11664-020-08303-7 |
Web of Science KeyUT | 000546531900001 |
Related Url | isVersionOf https://doi.org/10.1007/s11664-020-08303-7 |
FullText URL | fulltext.pdf |
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Author | Yamamoto, Haruchika| Sugimoto, Seiichiro| Kurosaki, Takeshi| Miyoshi, Kentaroh| Otani, Shinji| Okazaki, Mikio| Yamane, Masaomi| Oto, Takahiro| Toyooka, Shinichi| |
Published Date | 2020-06-29 |
Publication Title | Scientific Reports |
Volume | volume10 |
Issue | issue1 |
Publisher | Nature |
Start Page | 10595 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2020 |
File Version | publisher |
PubMed ID | 32601414 |
DOI | 10.1038/s41598-020-67433-4 |
Web of Science KeyUT | 000548360700030 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-020-67433-4 |
FullText URL | fulltext.pdf |
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Author | Lee, Yoon-Seok| Makino, Yuya| Nitta, Jun| Lee, Eunkyung| |
Keywords | aluminum alloy casting speed solidification Ohno continuous casting gravity casting dendritic spacing |
Published Date | 2020-05-11 |
Publication Title | Metals |
Volume | volume10 |
Issue | issue5 |
Publisher | MDPI |
Start Page | 625 |
ISSN | 2075-4701 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors. |
File Version | publisher |
DOI | 10.3390/met10050625 |
Web of Science KeyUT | 000540220000073 |
Related Url | isVersionOf https://doi.org/10.3390/met10050625 |
FullText URL | cis_5_2842.pdf |
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Author | Matsuo, Toshihiko| |
Keywords | Congenital blepharoptosis Anisometropia Levater muscle placation |
Published Date | 2020-06-13 |
Publication Title | Clinics in Surgery |
Volume | volume5 |
Publisher | Remedy |
Start Page | 2842 |
ISSN | 2474-1647 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | ©2020 Toshihiko Matsuo |
File Version | publisher |
Official Url | http://clinicsinsurgery.com/| |
FullText URL | cis_5_2847.pdf |
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Author | Matsuo, Toshihiko| |
Keywords | Trabeculectomy Filtering surgery In-the-bag intraocular lens dislocation Intraocular lens-suturing Conjunctiva-sparing |
Published Date | 2020-06-15 |
Publication Title | Clinics in Surgery |
Volume | volume5 |
Publisher | Remedy |
Start Page | 2847 |
ISSN | 2474-1647 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | ©2020 Toshihiko Matsuo |
File Version | publisher |
Official Url | http://www.clinicsinsurgery.com/| |
FullText URL | fulltext.pdf |
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Author | Iwamuro, Masaya| Miyahara, Koji| Sakaguchi, Chihiro| Takenaka, Ryuta| Kobayashi, Sayo| Mouri, Hirokazu| Tanaka, Shigetomi| Toyokawa, Tatsuya| Tanaka, Shouichi| Nishimura, Mamoru| Yamauchi, Kenji| Tanaka, Takehiro| Okada, Hiroyuki| |
Keywords | 18F-fluorodeoxyglucose-positron emission tomography mesenchymal tumor gastric neoplasms gastrointestinal stromal tumor schwannoma |
Published Date | 2020-05-01 |
Publication Title | Journal of Clinical Medicine |
Volume | volume9 |
Issue | issue5 |
Publisher | MDPI |
Start Page | 1301 |
ISSN | 2077-0383 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors. |
File Version | publisher |
PubMed ID | 32370028 |
DOI | 10.3390/jcm9051301 |
Web of Science KeyUT | 000540223800058 |
Related Url | isVersionOf https://doi.org/10.3390/jcm9051301 |
FullText URL | fulltext.pdf |
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Author | Wang, Wu| Yang, Jiajia| Wu, Qiong| Yu, Jiabin| Takahashi, Satoshi| Ejima, Yoshimichi| Wu, Jinglong| |
Keywords | between-session learning generalization tactile angle discriminability training time interval |
Published Date | 2019-10-25 |
Publication Title | Journal of Neurophysiology |
Volume | volume122 |
Issue | issue5 |
Publisher | American Physiological Society |
Start Page | 1918 |
End Page | 1927 |
ISSN | 0022-3077 |
NCID | AA00703334 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © the American Physiological Society |
File Version | publisher |
PubMed ID | 31461363 |
DOI | 10.1152/jn.00161.2019 |
Web of Science KeyUT | 000498170200008 |
Related Url | isVersionOf https://doi.org/10.1152/jn.00161.2019 |
Title Alternative | Pressure dependence of Si diffusion in gamma-Fe |
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FullText URL | fulltext.pdf |
Author | Tsujino, Noriyoshi| Mârza, Andreea| Yamazaki, Daisuke| |
Keywords | γ-Fe silicon diffusion high pressure planetary core |
Note | This is an Accepted Manuscript of an article published by Mineralogical Society of America.| |
Published Date | 2020-05-01 |
Publication Title | American Mineralogist |
Volume | volume105 |
Issue | issue3 |
Publisher | Mineralogical Society of America |
Start Page | 319 |
End Page | 324 |
ISSN | 0003-004X |
NCID | AA00521712 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | author |
DOI | 10.2138/am-2020-7197 |
Web of Science KeyUT | 000518370300003 |
Related Url | isVersionOf https://doi.org/10.2138/am-2020-7197 |
JaLCDOI | 10.18926/AMO/59959 |
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FullText URL | 74_3_251.pdf |
Author | Murakami, Takashi| Tokuda, Takanori| Nishimura, Shinsuke| Fujii, Hiromichi| Takahashi, Yosuke| Yamane, Kokoro| Inoue, Kazushige| Yamada, Koichi| Kakeya, Hiroshi| Shibata, Toshihiko| |
Abstract | A 62-year-old Japanese male presented with graft infection by Staphylococcus schleiferi 50 days after debranching of the left subclavian artery and frozen elephant trunk repair for the entry closure of a Stanford type B aortic dissection. The graft was removed, and the patient was successfully treated using in situ reconstruction of the arch with omental flap coverage, removal of the debranching graft, autologous iliac artery grafting, and longterm antibiotics. Domino reconstruction of the infected debranching graft using autologous external iliac artery and a Dacron graft can thus be a good option in similar cases. |
Keywords | autologous iliac artery graft Staphylococcus schleiferi graft infection domino reconstruction Dacron graft |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2020-06 |
Volume | volume74 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 251 |
End Page | 255 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 32577024 |
Web of Science KeyUT | 000543363400009 |
NAID | 120006862800 |
JaLCDOI | 10.18926/AMO/59952 |
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FullText URL | 74_3_215.pdf |
Author | Chou, Hsi-Hsien| |
Abstract | Due to cultural traditions, most Taiwanese do not have an advance directive or healthcare proxy. We explored how patients with mild dementia in Taiwan may still make self-determined decisions concerning advance directives for their healthcare and end-of-life care choices as the disease progresses. We examined 260 respondents with mild dementia at a Taiwan medical center: 199 patients who agreed (and 61 patients who disagreed) with the concept of advance directives completed a structured questionnaire. Multiple logistic regression models to determine the between-group differences revealed that the following were positively associated with approval of end-of-life directives: maintaining one’s quality of life (adjusted odds ratio [AOR], 2.44; 95% CI: 1.07-5.53), discussion with family members (AOR, 3.50; 95% CI: 1.49-8.26), and friend support networks (AOR, 3.36; 95% CI: 1.34-8.43). Cardiopulmonary resuscitation (AOR, 0.27; 95% CI: 0.09-0.79) was negatively associated with approval. There was also a positive association between the support of the legal validity of end-of-life directives (OR, 1.93; 95% CI: 1.07-3.48), without other confounding factors. In Taiwanese society, we remain mindful of cultural influences that may impact patients, including maintaining one’s quality of life, discussion with family members, and friend/support networks. These influences may help dementia patients complete their advance directives. |
Keywords | advance directive dementia patient autonomy quality of life culture |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2020-06 |
Volume | volume74 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 215 |
End Page | 220 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 32577019 |
Web of Science KeyUT | 000543363400005 |
NAID | 120006862794 |
JaLCDOI | 10.18926/AMO/59950 |
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FullText URL | 74_3_199.pdf |
Author | Fujita, Hirofumi| Bando, Tetsuya| Oyadomari, Seiichi| Ochiai, Kazuhiko| Watanabe, Masami| Kumon, Hiromi| Ohuchi, Hideyo| |
Abstract | Dickkopf 3 (Dkk3) is a secreted protein belonging to the Dkk family and encoded by the orthologous gene of REIC. Dkk3/REIC is expressed by mouse and human adrenal glands, but the understanding of its roles in this organ is still limited. To determine the functions of Dkk3 in the mouse adrenal gland, we first identified that the mouse Dkk3 protein is N-glycosylated in the adrenal gland as well as in the brain. We performed proteome analysis on adrenal glands from Dkk3-null mice, in which exons 5 and 6 of the Dkk3 gene are deleted. Twodimensional polyacrylamide gel electrophoresis of adrenal proteins from wild-type and Dkk3-null mice revealed 5 protein spots whose intensities were altered between the 2 genotypes. Mass spectrometry analysis of these spots identified binding immunoglobulin protein (BiP), an endoplasmic reticulum (ER) chaperone. To determine whether mouse Dkk3 is involved in the unfolded protein response (UPR), we carried out a reporter assay using ER-stress responsive elements. Forced expression of Dkk3 resulted in the induction of distinct levels of reporter expression, showing the UPR initiated by the ER membrane proteins of activating transcription factor 6 (ATF6) and inositol-requring enzyme 1 (IRE1). Thus, it is possible that Dkk3 is a physiological ER stressor in the mouse adrenal gland. |
Keywords | Dkk3 knockout mouse adrenal gland glucose-regulated protein 78 proteome endoplasmic reticulum stress |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2020-06 |
Volume | volume74 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 199 |
End Page | 208 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 32577017 |
Web of Science KeyUT | 000543363400003 |
NAID | 120006862792 |
JaLCDOI | 10.18926/AMO/59949 |
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FullText URL | 74_3_191.pdf |
Author | Ohashi, Keiji| Sada, Ken-Ei| Asano, Yosuke| Hayashi, Keigo| Yamamura, Yuriko| Asano, Sumie Hiramatsu| Miyawaki, Yoshia| Morishita, Michiko| Katsuyama, Eri| Watanabe, Haruki| Tatebe, Noriko| Narazaki, Mariko| Matsumoto, Yoshinori| Sunahori-Watanabe, Katsue| Kawabata, Tomoko| Yajima, Nobuyuki| Wada, Jun| |
Abstract | Chronic damage accumulation affects not only mortality but also quality of life in patients with systemic lupus erythematosus (SLE). Risk factors for chronic damage were explored in SLE through different onset eras. Two hundred forty-five patients at Okayama University Hospital and Showa University Hospital were divided into three groups based on the onset era: a past-onset group (onset before 1995; n=83), middle-onset group (1996-2009; n=88), and recent-onset group (after 2010; n=74). The mean Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI) score as an index of chronic damage was 1.93, 1.24, and 0.53 in the past-, middle-, and recent-onset groups, respectively. In the pastonset group, the total SDI score was significantly associated with glucocorticoid monotherapy by linear regression analysis (β-coefficient [β]=0.63; 95% confidence interval [CI], 0.21-1.05) and C-reactive protein levels (β=0.67; 95% CI, 0.27-1.07). In the middle-onset group, the total SDI score was significantly associated with the SLE Disease Activity Index at registration (β=0.09; 95% CI, 0.03-0.12). Reducing the accumulation of chronic damage in SLE patients might be possible with the concomitant use of immunosuppressants and tight control of disease activity. |
Keywords | systemic lupus erythematosus chronic damage glucocorticoids, disease activity disease duration |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2020-06 |
Volume | volume74 |
Issue | issue3 |
Publisher | Okayama University Medical School |
Start Page | 191 |
End Page | 198 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 32577016 |
Web of Science KeyUT | 000543363400002 |
NAID | 120006862791 |
FullText URL | fulltext.pdf |
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Author | Kondo, Hideki| Fujita, Miki| Hisano, Hiroshi| Hyodo, Kiwamu| Andika, Ida Bagus| Suzuki, Nobuhiro| |
Keywords | negevirus kitavirus aphid virome RNA seq barley diversity horizontal transmission |
Published Date | 2020-04-07 |
Publication Title | Frontiers in Microbiology |
Volume | volume11 |
Publisher | Frontiers Media |
Start Page | 509 |
ISSN | 1664-302X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 Kondo, Fujita, Hisano, Hyodo, Andika and Suzuki. |
File Version | publisher |
PubMed ID | 32318034 |
DOI | 10.3389/fmicb.2020.00509 |
Web of Science KeyUT | 000529047600001 |
Related Url | isVersionOf https://doi.org/10.3389/fmicb.2020.00509 |
FullText URL | fulltext.pdf |
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Author | Katsui, Kuniaki| Ogata, Takeshi| Watanabe, Kenta| Katayama, Norihisa| Kuroda, Masahiro| Kiura, Katsuyuki| Hiraki, Takao| Maeda, Yoshinobu| Toyooka, Shinichi| Kanazawa, Susumu| |
Keywords | cisplatin docetaxel dose-volume histogram non-small cell lung cancer PACIFIC trial radiation pneumonitis |
Published Date | 2020-05-04 |
Publication Title | Cancer Medicine |
Publisher | Wiley |
ISSN | 2045-7634 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 The Authors. |
File Version | publisher |
PubMed ID | 32364685 |
DOI | 10.1002/cam4.3093 |
Web of Science KeyUT | 000530411600001 |
Related Url | isVersionOf https://doi.org/10.1002/cam4.3093 |
FullText URL | fulltext.pdf |
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Author | Paneer Selvam, Karthik| Nakagawa, Tomohiro| Marui, Tatsuki| Inoue, Hirotaka| Nishikawa, Takeshi| Hayashi, Yasuhiko| |
Keywords | carbon nanohorns cellulose conductive sheets vapor sensor |
Published Date | 2020-05-04 |
Publication Title | Materials Research Express |
Volume | volume7 |
Issue | issue5 |
Publisher | IOP Publishing |
Start Page | 056402 |
ISSN | 2053-1591 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 The Author(s). |
File Version | publisher |
DOI | 10.1088/2053-1591/ab89dc |
Web of Science KeyUT | 000531254300001 |
Related Url | isVersionOf https://doi.org/10.1088/2053-1591/ab89dc |
File URL | 07200kingayaturi.jpg |
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APG3family | カヤツリグサ科 (Cyperaceae) |
YList | ylist.info/ylist_detail_display.php?pass=2073 |
Database | Naturalized plants in Japan : Seed-Image database |
Database(alternative) | Naturalized plants in Japan : Seed-Image database |
Publisher | 岡山大学 資源植物科学研究所 野生植物グループ |
Resource Type | Data or Dataset |
Official URL | http://www.rib.okayama-u.ac.jp/wild/okayama_kika_v2/Seed-image-database-J.html| |
File URL | 15226hosomikingayaturi.jpg k-hosomikingayaturi.jpg |
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APG3family | カヤツリグサ科 (Cyperaceae) |
YList | ylist.info/ylist_detail_display.php?pass=27969 |
Database | Naturalized plants in Japan : Seed-Image database |
Database(alternative) | Naturalized plants in Japan : Seed-Image database |
Publisher | 岡山大学 資源植物科学研究所 野生植物グループ |
Resource Type | Data or Dataset |
Official URL | http://www.rib.okayama-u.ac.jp/wild/okayama_kika_v2/Seed-image-database-J.html| |