result 1320 件
FullText URL | fulltext.pdf |
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Author | La, The Mon| Tachibana, Hiromi| Li, Shun-Ai| Abe, Tadashi| Seiriki, Sayaka| Nagaoka, Hikaru| Takashima, Eizo| Takeda, Tetsuya| Ogawa, Daisuke| Makino, Shin-Ichi| Asanuma, Katsuhiko| Watanabe, Masami| Tian, Xuefei| Ishibe, Shuta| Sakane, Ayuko| Sasaki, Takuya| Wada, Jun| Takei, Kohji| Yamada, Hiroshi| |
Keywords | dynamin microtubules podocyte primary process |
Published Date | 2020-10-17 |
Publication Title | FASEB Journal |
Volume | volume34 |
Issue | issue12 |
Publisher | Wiley |
Start Page | 16449 |
End Page | 16463 |
ISSN | 0892-6638 |
NCID | AA1066874X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 The Authors. |
File Version | publisher |
PubMed ID | 33070431 |
DOI | 10.1096/fj.202001240RR |
NAID | 120006900792 |
Web of Science KeyUT | 000581167100001 |
Related Url | isVersionOf https://doi.org/10.1096/fj.202001240RR |
FullText URL | fulltext.pdf |
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Author | Osumi, Ryuta| Wang, Ziyi| Ishihara, Yoshihito| Odagaki, Naoya| Iimura, Tadahiro| Kamioka, Hiroshi| |
Keywords | Sclerostin distribution Lacuno-canalicular system Mechanical unloading |
Note | This is an Accepted Manuscript of an article published by Springer.| |
Published Date | 2020-08-25 |
Publication Title | Journal of Bone and Mineral Metabolism |
Volume | volume39 |
Publisher | Springer |
Start Page | 148 |
End Page | 159 |
ISSN | 0914-8779 |
NCID | AA10747551 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | author |
PubMed ID | 32844318 |
DOI | 10.1007/s00774-020-01135-9 |
Web of Science KeyUT | 000562686600001 |
Related Url | isVersionOf https://link.springer.com/article/10.1007/s00774-020-01135-9 |
JaLCDOI | 10.18926/AMO/60805 |
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FullText URL | 74_5_435.pdf |
Author | Fujishita, Keigo| Oka, Satoshi| Kamei, Katsuhiko| Tani, Katsuma| Fujisawa, Yuka| Kitamura, Wataru| Machida, Takuya| Imai, Toshi| |
Abstract | A 53-year-old man was diagnosed with acute myeloid leukemia, which was refractory to chemotherapies. Systemic papules appeared afterward. The skin biopsies revealed filamentous fungal infection including fusariosis. Despite antifungal therapy, the infection did not resolve, because neutropenia persisted with the leukemia. He underwent hematopoietic stem cell transplantation (HSCT) to overcome the leukemia and restore normal hematopoiesis but died from fusariosis just before engraftment. Fusarium fujikuroi species complex was detected in blood cultures with poor antifungal susceptibility. Because restoring normal hematopoiesis is important in the treatment of fusariosis, HSCT might be considered for patients with persistent pancytopenia. |
Keywords | disseminated fusariosis Fusarium fujikuroi species complex allogeneic hematopoietic stem cell transplantation acute myeloid leukemia |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2020-10 |
Volume | volume74 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 435 |
End Page | 441 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 33106701 |
Web of Science KeyUT | 000581970100010 |
NAID | 120006892931 |
JaLCDOI | 10.18926/AMO/60799 |
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FullText URL | 74_5_401.pdf |
Author | Tsukioki, Takahiro| Shien, Tadahiko| Ohtani, Yusuke| Fujihara, Miwa| Suzuki, Yoko| Kajihara, Yukiko| Hatono, Minami| Kawada, Kengo| Kochi, Mariko| Iwamoto, Takayuki| Ikeda, Hirokuni| Taira, Naruto| Doihara, Hiroyoshi| |
Abstract | Differentiated thyroid carcinoma (DTC) in juvenile patients is often an extensive and aggressive disease with a high frequency of recurrence. However, the prognosis is excellent, with a low mortality rate even when advanced disease is present, although prognostic factors and treatment strategy remain uncertain. Between April 2004 and March 2017, 33 juvenile patients (< 30 years old) were diagnosed with DTC and treated at our institution. We retrospectively investigated prognosis and factors including sex, reason for discovery, treatment, pathological factors and treatment progress to clarify the risk factors. All patients underwent curative surgical treatment. Pathologically, lymph node metastasis was identified in 25 patients (75%). Thirteen patients (39%) had bilateral cervical metastasis. In addition, 9 (27%) had more than 10 metastatic lymph nodes. The 2 patients with more than 20 metastatic lymph nodes were treated with radioactive iodine (RAI). Five patients (15%) had local recurrences and received surgery. There have been no further recurrences or deaths. However, no factors were determined to significantly predict the recurrence of juvenile DTC. Local recurrent disease was treated with surgery and/or RAI until remission, and survival was excellent in juvenile DTC. |
Keywords | differentiated thyroid carcinoma juvenile children |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2020-10 |
Volume | volume74 |
Issue | issue5 |
Publisher | Okayama University Medical School |
Start Page | 401 |
End Page | 406 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 33106695 |
Web of Science KeyUT | 000581970100004 |
NAID | 120006892925 |
FullText URL | fulltext.pdf |
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Author | Nojima, Ichiro| Eikawa, Shingo| Tomonobu, Nahoko| Hada, Yoshiko| Kajitani, Nobuo| Teshigawara, Sanae| Miyamoto, Satoshi| Tone, Atsuhito| Uchida, Haruhito A.| Nakatsuka, Atsuko| Eguchi, Jun| Shikata, Kenichi| Udono, Heiichiro| Wada, Jun| |
Keywords | Cytokines Diabetes Endocrine system and metabolic diseases Immunology Tumour immunology |
Published Date | 2020-09-10 |
Publication Title | Scientific Reports |
Volume | volume10 |
Issue | issue1 |
Publisher | Nature Research |
Start Page | 14928 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2020 |
File Version | publisher |
PubMed ID | 32913271 |
DOI | 10.1038/s41598-020-71946-3 |
Web of Science KeyUT | 000571915100049 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-020-71946-3 |
FullText URL | fulltext.pdf |
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Author | Mitalo, Oscar W.| Otsuki, Takumi| Okada, Rui| Obitsu, Saeka| Masuda, Kanae| Hojo, Yuko| Matsuura, Takakazu| Mori, Izumi C.| Abe, Daigo| Asiche, William O.| Akagi, Takashi| Kubo, Yasutaka| Ushijima, Koichiro| |
Keywords | 1-methylcyclopropene carotenoids chlorophyll Citrus limon ethylene low temperature peel degreening phytohormones transcriptome |
Published Date | 2020-05-06 |
Publication Title | Journal of Experimental Botany |
Volume | volume71 |
Issue | issue16 |
Publisher | Oxford University Press |
Start Page | 4778 |
End Page | 4796 |
ISSN | 0022-0957 |
NCID | AA00697526 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2020. |
File Version | publisher |
PubMed ID | 32374848 |
DOI | 10.1093/jxb/eraa206 |
Web of Science KeyUT | 000573250000015 |
Related Url | isVersionOf https://doi.org/10.1093/jxb/eraa206 |
FullText URL | fulltext.pdf |
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Author | Tsuji, Kenji| Kitamura, Shinji| Sang, Yizhen| Fukushima, Kazuhiko| Wada, Jun| |
Keywords | Kidney stem cell Regeneration Acute kidney injury Growth factor |
Published Date | 2020-07 |
Publication Title | Stem Cell Research |
Volume | volume46 |
Publisher | Elsevier |
Start Page | 101865 |
ISSN | 1873-5061 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 The Authors. |
File Version | publisher |
PubMed ID | 32505897 |
DOI | 10.1016/j.scr.2020.101865 |
Web of Science KeyUT | 000568783800002 |
Related Url | isVersionOf https://doi.org/10.1016/j.scr.2020.101865 |
FullText URL | fulltext.pdf |
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Author | Matsuoka-Uchiyama, Natsumi| Tsuji, Kenji| Fukushima, Kazuhiko| Kitamura, Shinji| Uchida, Haruhito A.| Sugiyama, Hitoshi| Takahashi, Naoki| Iwano, Masayuki| Wada, Jun| |
Published Date | 2020-06-18 |
Publication Title | Kidney International Reports |
Volume | volume5 |
Issue | issue9 |
Publisher | Elsevier |
Start Page | 1576 |
End Page | 1580 |
ISSN | 24680249 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 International Society of Nephrology |
File Version | publisher |
PubMed ID | 32954083 |
DOI | 10.1016/j.ekir.2020.06.010 |
Related Url | isVersionOf https://doi.org/10.1016/j.ekir.2020.06.010 |
FullText URL | fulltext.pdf |
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Author | Shen, Lianhua| Yamamoto, Takushi| Tan, Xian Wen| Ogata, Koretsugu| Ando, Eiji| Ozeki, Eiichi| Matsuura, Eiji| |
Keywords | Atherosclerosis Low-density lipoprotein (LDL) Oxidized LDL (oxLDL) Oxidized lipids; Imaging mass microscopy (iMScope) Mass spectroscopy (MS) |
Published Date | 2020-08-28 |
Publication Title | Atherosclerosis |
Volume | volume311 |
Publisher | Elsevier |
Start Page | 1 |
End Page | 12 |
ISSN | 00219150 |
NCID | AA00553457 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
File Version | author |
PubMed ID | 32911376 |
DOI | 10.1016/j.atherosclerosis.2020.08.001 |
Related Url | isVersionOf https://doi.org/10.1016/j.atherosclerosis.2020.08.001 |
FullText URL | fulltext.pdf |
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Author | Shikata, Kenichi| Haneda, Masakazu| Ninomiya, Toshiharu| Koya, Daisuke| Suzuki, Yoshiki| Suzuki, Daisuke| Ishida, Hitoshi| Akai, Hiroaki| Tomino, Yasuhiko| Uzu, Takashi| Nishimura, Motonobu| Maeda, Shiro| Ogawa, Daisuke| Miyamoto, Satoshi| Makino, Hirofumi| the Diabetic Nephropathy Remission and Regression Team Trial in Japan (DNETT‐Japan) collaborative group| |
Keywords | Diabetic kidney disease Diabetic nephropathy Diabetic Nephropathy Remission and Regression Team Trial in Japan |
Published Date | 2020-08-08 |
Publication Title | Journal of Diabetes Investigation |
Volume | volume12 |
Issue | issue2 |
Publisher | Wiley |
Start Page | 207 |
End Page | 216 |
ISSN | 2040-1116 |
NCID | AA12488319 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 The Authors |
File Version | publisher |
PubMed ID | 32597548 |
DOI | 10.1111/jdi.13339 |
NAID | 120006880216 |
Web of Science KeyUT | 000557091100001 |
Related Url | isVersionOf https://doi.org/10.1111/jdi.13339 |
JaLCDOI | 10.18926/AMO/60370 |
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FullText URL | 74_4_319.pdf |
Author | Isoyama, Satoshi| Kimura, Satoshi| Morimatsu, Hiroshi| |
Abstract | Little is known about the role of a strong ions in humans with respiratory abnormalities. In this study, we investigated the associations between partial carbon dioxide pressure (pCO2) and each of sodium ion (Na+) concentrations, chloride ion (Cl−) concentrations and their difference (SIDNa-Cl). Blood gas data were obtained from patients in a teaching hospital intensive care unit between August 2013 and January 2017. The association between pCO2 and SIDNa-Cl was defined as the primary outcome. The associations between pCO2 and [Cl−], [Na+] and other strong ions were secondary outcomes. pCO2 was stratified into 10 mmHg-wide bands and treated as a categorical variable for comparison. As a result, we reviewed 115,936 blood gas data points from 3,840 different ICU stays. There were significant differences in SIDNa-Cl, [Cl−], and [Na+] among all categorized pCO2 bands. The respective pCO2 SIDNa-Cl, [Cl−], and [Na+] correlation coefficients were 0.48, −0.31, and 0.08. SIDNa-Cl increased and [Cl−] decreased with pCO2, with little relationship between pCO2 and [Na+] across subsets. In conclusion, we found relatively strong correlations between pCO2 and SIDNa-Cl in the multiple blood gas datasets examined. Correlations between pCO2 and chloride concentrations, but not sodium concentrations, were further found to be moderate in these ICU data. |
Keywords | acid-base phenomena Stewart approach strong ion difference chlorine ion partial carbon dioxide pressure |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2020-08 |
Volume | volume74 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 319 |
End Page | 325 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 32843763 |
Web of Science KeyUT | 000562508700007 |
NAID | 120006880209 |
JaLCDOI | 10.18926/AMO/60368 |
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FullText URL | 74_4_301.pdf |
Author | Takahashi, Kei| Kitamura, Yoshihisa| Ushio, Soichiro| Sendo, Toshiaki| |
Abstract | Ketamine has been clinically proven to ameliorate depression, including treatment-resistant depression. The detailed mechanism of action of ketamine in treatment-resistant depression remains unclear. We examined the effects of ketamine on the immobility times of adrenocorticotropic hormone (ACTH)-treated rats during the forced swim test, and we explored the mechanism by which ketamine acts in this model. We investigated the neuroanatomical site of action by microinjecting ketamine into the medial prefrontal cortex of rats. A significant reduction of the rats’ immobility during the forced swim test was observed after the intraperitoneal injection of ketamine in both saline- and ACTH-treated rats. The microinjection of ketamine into the medial prefrontal cortex also decreased immobility during the forced swim test in both saline- and ACTH-treated rats. The immobility-decreasing effect of intraperitoneally injected ketamine was blocked by administering WAY100635, a 5-HT1A receptor antagonist, into the medial prefrontal cortex. These findings contribute to the evidence that ketamine can be useful against treatment-resistant depressive conditions. The immobility-reducing effects of ketamine might be mediated by 5-HT1A receptor activity in the medial prefrontal cortex. |
Keywords | ketamine adrenocorticotropic hormone forced swim test medial prefrontal cortex 5-HT1A receptor |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2020-08 |
Volume | volume74 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 301 |
End Page | 306 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2020 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 32843761 |
Web of Science KeyUT | 000562508700005 |
NAID | 120006880207 |
FullText URL | fulltext.pdf |
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Author | Kitamura, Shinji| Takahashi, Kensaku| Sang, Yizhen| Fukushima, Kazuhiko| Tsuji, Kenji| Wada, Jun| |
Keywords | immunofluorescent image renal pathology artificial intelligence deep learning diabetic nephropathy |
Published Date | 2020-07-09 |
Publication Title | Diagnostics |
Volume | volume10 |
Issue | issue7 |
Publisher | MDPI |
Start Page | 466 |
ISSN | 2075-4418 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors. |
File Version | publisher |
PubMed ID | 32660112 |
DOI | 10.3390/diagnostics10070466 |
Web of Science KeyUT | 000557155500001 |
Related Url | isVersionOf https://doi.org/10.3390/diagnostics10070466 |
FullText URL | fulltext.pdf |
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Author | Hada, Yoshiko| Uchida, Haruhito A.| Otaka, Nozomu| Onishi, Yasuhiro| Okamoto, Shugo| Nishiwaki, Mariko| Takemoto, Rika| Takeuchi, Hidemi| Wada, Jun| |
Keywords | chlorogenic acid vascular senescence nuclear factor erythroid 2-related factor 2 heme oxygenase-1 |
Published Date | 2020-06-25 |
Publication Title | International Journal of Molecular Sciences |
Volume | volume21 |
Issue | issue12 |
Publisher | MDPI |
Start Page | 4527 |
ISSN | 1661-6596 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors. |
File Version | publisher |
PubMed ID | 32630570 |
DOI | 10.3390/ijms21124527 |
Web of Science KeyUT | 000554678300001 |
Related Url | isVersionOf https://doi.org/10.3390/ijms21124527 |
FullText URL | fulltext.pdf |
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Author | Tanabe, Katsuyuki| Kanzaki, Hiromitsu| Wada, Takahira| Nakashima, Yuri| Sugiyama, Hitoshi| Okada, Hiroyuki| Wada, Jun| |
Keywords | case report gastric cancer IgA nephropathy nivolumab steroid |
Published Date | 2020-05-22 |
Publication Title | Medicine |
Volume | volume99 |
Issue | issue21 |
Publisher | Lippincott, Williams & Wilkins |
Start Page | e20464 |
ISSN | 0025-7974 |
NCID | AA00728867 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 the Author(s). |
File Version | publisher |
PubMed ID | 32481351 |
DOI | 10.1097/MD.0000000000020464 |
Web of Science KeyUT | 000551508200106 |
Related Url | isVersionOf https://doi.org/10.1097/MD.0000000000020464 |
FullText URL | fulltext.pdf |
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Author | Yanpirat, Patcha| Nakatsuji, Yukari| Hiraga, Shota| Fujitani, Yoshiko| Izumi, Terumi| Masuda, Sachiko| Mitsui, Ryoji| Nakagawa, Tomoyuki| Tani, Akio| |
Keywords | lanthanide methylotroph XoxF methanol dehydrogenase Methylobacteriumspecies |
Published Date | 2020-05-30 |
Publication Title | Microorganisms |
Volume | volume8 |
Issue | issue6 |
Publisher | MDPI |
Start Page | 822 |
ISSN | 2076-2607 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors. |
File Version | publisher |
PubMed ID | 32486139 |
DOI | 10.3390/microorganisms8060822 |
Web of Science KeyUT | 000549300700001 |
Related Url | isVersionOf https://doi.org/10.3390/microorganisms8060822 |
FullText URL | fulltext.pdf |
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Author | Miyake, Hiromasa| Tanabe, Katsuyuki| Tanimura, Satoshi| Nakashima, Yuri| Morioka, Tomoyo| Masuda, Kana| Sugiyama, Hitoshi| Sato, Yasufumi| Wada, Jun| |
Keywords | acute kidney injury ischemia-reperfusion oxidative stress vasohibin-2 peritubular capillaries |
Published Date | 2020-06-26 |
Publication Title | International Journal of Molecular Sciences |
Volume | volume21 |
Issue | issue12 |
Publisher | MDPI |
Start Page | 4545 |
ISSN | 1422-0067 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors. |
File Version | publisher |
PubMed ID | 32604722 |
DOI | 10.3390/ijms21124545 |
Web of Science KeyUT | 000549478900001 |
Related Url | isVersionOf https://doi.org/10.3390/ijms21124545 |
FullText URL | fulltext.pdf |
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Author | Sang, Yizhen| Tsuji, Kenji| Inoue-Torii, Akiko| Fukushima, Kazuhiko| Kitamura, Shinji| Wada, Jun| |
Keywords | semaphorin3A podocyte proteinuria apoptosis c-Jun N-terminal kinase |
Published Date | 2020-06-08 |
Publication Title | International Journal of Molecular Sciences |
Volume | volume21 |
Issue | issue11 |
Publisher | MDPI |
Start Page | 4099 |
ISSN | 1422-0067 |
NCID | AA12038549 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors. |
File Version | publisher |
PubMed ID | 32521824 |
DOI | 10.3390/ijms21114099 |
Web of Science KeyUT | 000543400300361 |
Related Url | isVersionOf https://doi.org/10.3390/ijms21114099 |
FullText URL | fulltext.pdf |
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Author | Fukushima, Kazuhiko| Kitamura, Shinji| Tsuji, Kenji| Sang, Yizhen| Wada, Jun| |
Keywords | sodium glucose co-transporter 2 inhibitor mammalian target of rapamycin (mTOR) autophagy obesity multi lamellar body |
Published Date | 2020-06-05 |
Publication Title | International Journal of Molecular Sciences |
Volume | volume21 |
Issue | issue11 |
Publisher | MDPI |
Start Page | 4054 |
ISSN | 1422-0067 |
NCID | AA12038549 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 by the authors |
File Version | publisher |
PubMed ID | 32517059 |
DOI | 10.3390/ijms21114054 |
Web of Science KeyUT | 000543400300316 |
Related Url | isVersionOf https://doi.org/10.3390/ijms21114054 |
FullText URL | fulltext.pdf |
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Author | Yamamura, Yuriko| Matsumoto, Yoshinori| Tadokoro, Koh| Ohta, Yasuyuki| Sato, Kota| Yamashita, Toru| Yamamura, Masahiro| Sada, Ken-Ei| Abe, Koji| Wada, Jun| |
Keywords | Noninvasive pressure support ventilation Statin-associated necrotizing myopathy BIPAP |
Published Date | 2020-06-03 |
Publication Title | BMC Pulmonary Medicine |
Volume | volume20 |
Issue | issue1 |
Publisher | BMC |
Start Page | 156 |
ISSN | 1471-2466 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s). 2020 |
File Version | publisher |
PubMed ID | 32493279 |
DOI | 10.1186/s12890-020-01195-7 |
Web of Science KeyUT | 000540247100001 |
Related Url | isVersionOf https://doi.org/10.1186/s12890-020-01195-7 |