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Author 岡山大学温泉研究所|
Published Date 1972-03-25
Publication Title 岡山大学温泉研究所報告
Volume volume41
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1972-03-25
Publication Title 岡山大学温泉研究所報告
Volume volume41
Content Type Others
JaLCDOI 10.18926/40155
Title Alternative Esophagus hiatal hernia with special reference to the early stage
FullText URL pitsr_041_063_068.pdf
Author Noishiki, Yasuharu| Komoto, Yoshiaki| Nakahara, Yasuhiro|
Abstract In the aged, hiatal hernia should be recognized as it has developed; it develops progressively. Special attention should be given to the early stage of hiatal hernia from the genetic point of view. Like other organs in the aged, aging changes around a hiatus are inevitable; relaxing of esophageal diaphragmatic ligament and weakening of muscle power of diaphragmatic vertebral part move on with age. After all, valve structure at hiatus, Goubaroff's valve, is so weakened its function and in the stomach, "His angle" is so widened, that the stomach becomes wedge shaped against the hiatus. The more the pressure in the stomach increases, the larger the wedge shapes. Under these conditions, when the abdominal pressure rises by the acts of coughing or defecation, hiatus may be widened and the wedge may be pushed into the hiatus. There are no strong valve and or ligament enough to keep the wedge part of stomach in peritoneal cavity. In the stomach, the pressure of the expelling meal is equal to that of the widening wedge. On the other hand, in the peritoneal cavity, pressure produced by the act of defecation is equal to that of ejecting the wedge through hiatus. These are self-evident from the Pascal's principle. Hiatal hernia is produced under these conditions. We, therefore, should call the attention to the early genetic stage of hiatal hernia. In Japan, hiatal hernia has been recognized when it gets larger and fixes out of the peritoneal cavity. But in the early stage, it also must be noted as hiatal hernia.
Publication Title 岡山大学温泉研究所報告
Published Date 1972-03-25
Volume volume41
Start Page 63
End Page 68
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398151
JaLCDOI 10.18926/40154
Title Alternative Report of a case of severe mechanical joundice -Successfully treated by jejuno-hepatic ducts anastomoses
FullText URL 041_057_062.pdf
Author Noishiki, Yasuharu| Kotakemori, Michiaki| Komoto, Yoshiaki| Nakahara, Yasuhiro|
Abstract Jejuno hepatic ducts anastomoses were successfully performed by carefull managements. Because of dense adhesion at hilus of liver, around the gall bladder and choledocus, dissection of common duct, cystic duct, hepatic ducts and even gall bladder was very difficult anatomically. Resecting a inflammatory granulative tumor, including gall bladder, choledocus, lesser omentum and hepatocluodenal ligament en mass, we found that only very short hepatic ducts with inflammatory granulation tissue were remained open. Reconstruction of biliary passages was done using Roux. Y. method with loop jejunum. It needed very carefull procedure to avoid suture failure, ascending infection (cholangitis) and postoperative stenoses at the site of the anastomoses. The anastomoses were performed using atraumatic 3-0 Tefdek ; interrupted and each big bite of duct wall together with surrounding thickend granulative tissue, in order to keep capillary blood supply effective and to minimize the anastomotic trauma which were very important for wound healing. Patient is healthy, enjoying his normal life and his liver function tests are within normal range, 1 1/2 years postoperatively.
Publication Title 岡山大学温泉研究所報告
Published Date 1972-03-25
Volume volume41
Start Page 57
End Page 62
ISSN 0369-7142
language Japanese
File Version publisher
NAID 40017532304
JaLCDOI 10.18926/40153
Title Alternative Absorption of Medium-chain triglyceride (MCT) in isolated intestinal loops of dog and its effect upon the lipids of serum aud adipose tissue
FullText URL pitsr_041_049_056.pdf
Author Kotakemori, Michiaki|
Abstract The absorption of medium chain triglyceride (MCT) has been investigated with intestinal loop of dog without both bile and pancreatic juce. On optimal state, the average coefficient of fat absorption was 78.1±7.4%. The use of medium chain triglyceride diet for 4 weeks in dogs had some effecton lipids of serum and adipose tissue but minimal change on clinical evidence was found. There was a prompt reduction in the proportion of arachidonic acid and a sustained increase in the proportion of oleic acid and linoleic acid in serum lipid. Analysis on lipids of adipose tissue showed prompt reduction in the proportion of oleic acid and linoleic acid. Neither clinical evidence nor side effect induced with medium chain triglyceride was found.
Publication Title 岡山大学温泉研究所報告
Published Date 1972-03-25
Volume volume41
Start Page 49
End Page 56
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398150
JaLCDOI 10.18926/40152
Title Alternative Studies on chrysotherapy in rheumatoid arthritis, III. Gold determination by the atomic absorption spectrophotometry
FullText URL 041_035_048.pdf
Author Takahashi, Kazue|
Abstract The gold concentration in serum, synovial fluid and urine has been determined using a HITACHI MODEL 207 atomic absorption spectrophotometer. Flow rate of acetylene was setted at 2.0l/min. and lamp current was setted at 8mA. The samples were pretreated by the determination of gold. Serum was diluted with deionized water by two to ten-fold. To O.2ml. of synoival fluid 50units/ml of hyaluronidase was added and then incubated for 20 minutes at 37℃. This sample was then treated the procedure for serum given previously. Urine was treated using the modification method of Christions procedure. The recovery rates with gold sodium thiomalate in serum, synovial fluid and urine were 99.9%, 102.5% and 93.6% respectively. When gold sodium thiomalate was injected in rabbits, the maximum serum gold level was attained 1 hour after injection and then gradually decreased at about 50% of the maximum level 24 hours after injection. In the observations of changes in the gold levels in the serum of patients with rheumatoid arthritis after injection of gold sodium thiomalate and gold thioglucose, its peak level after gold thioglucose injection tended to be slightly lower as compared with the same amount of gold sodium thiomalate injection. In those patients who had been given 300 mg. or more of gold salt-preparation, one additional injection of 25 mg. of gold salt could attain the gold level of around 200μg/100ml, in serum a week later, and this level was very nearly the same with that after 3-4 days of one additional injection of 1Omg. of gold salt. The amount of gold excreted in the urine varied from patient to patient, and the mean excretion rates of gold sodium thiomalate and gold thioglucose in the urine within 24 hours after intramuscular administralion were 9.8% and 6.5% respectively. The simple, rapid and accurate method for analysis in biological specimens using atomic absorption spectrophotometer would offer one of the excellent measures in the clinical management of patients with rheumatoid arthritis.
Publication Title 岡山大学温泉研究所報告
Published Date 1972-03-25
Volume volume41
Start Page 35
End Page 48
ISSN 0369-7142
language Japanese
File Version publisher
NAID 40017532302
Author Inoue, Taeko| Morinaga, Hiroshi|
Published Date 1972-03-25
Publication Title 岡山大学温泉研究所報告
Volume volume41
Content Type Data or Dataset
JaLCDOI 10.18926/40150
Title Alternative On the measurement of oxygen and carbon isotopic ratios of carbonates
FullText URL pitsr_041_009_012.pdf
Author Watanabe, Makoto| Matsubaya, Osamu|
Abstract Oxygen and carbon isotopic ratios of two working standards of our laboratory and three other standards were measured by McCrea's technique and the new McKINNEY type mass spectrometer in this Institute. The reproducibility of δ(13)C measurement is about ±0.2‰. Some systematic differences in δ(18)O values were observed among the three measurements in Apr.-May, July, and Aug., 1971. Because these systematic differences are supposed to be caused by the imperfection in the processes of decomposition of carbonates by phosphoric acid, the reproducibility of δ(18)O measurement may be ±O.2‰ in most cases. The calibrations of our working standard, CK-13, against the PDB standard were carried out on the assumption that δ(18)O and δ(13)C of CK-13 are -1.75‰ and +O.54‰ relative to PDB, respectively. The accuracy of these calibrations is about ±O.2‰ as shown by the interlaboratory comparison of some standards (Table 3). The δ(18)O values of the two working standards relative to PDB are independently recalculated relative to SMOW based on the two assumptions (Table 4). One of which is that a standard water MSA-2 is -8.20‰ relative to SMOW, and the other is that the δ(18)O of CK-13 is -1.75‰ relative to PDB. The results of both calculations agree within 0.4‰.
Publication Title 岡山大学温泉研究所報告
Published Date 1972-03-25
Volume volume41
Start Page 9
End Page 12
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398149
JaLCDOI 10.18926/40149
Title Alternative A subsequent report on the new McKinney type mass spectrometer in the Institute for Thermal Spring Research, Okayama University
FullText URL pitsr_041_003_007.pdf
Author Matsubaya, Osamu|
Abstract Since the installation in April 1970, the McKinney type mass spectrometer has maintained a good condition and about 5000 isotopic analyses of oxygen, carbon and sulfer has been cerried out so far. The ion source filament was changed to spiral one from single wire. Consequently three times sensitivity and the longer life of filament were obtained. Gradual changes in the ratio of potential divider (β) and the sensitivity (|△ E(0)(2)|/E(0)(1)) for the difference of β have been observed (Table 1). Because these changes are opposite in trend but similar in degree, it is supposed that these changes are caused by decrease of feed-back resister value in the balancing system. Although there remain some problems in the corrections for the difference in observed isotopic tatio between two cases that a same CO(2) is fed to ion source from the ST side of inlet system on the one hand and from the X side on the another, the reproducibility of the measurement of isotopic ratio for long period is about ±O.1‰ (Table 2, Fig. 1). δ(18)O values of standard waters, MSA-1 and MSA-2, measured during a period from May to Dec. 1970 and in Sep. 1971 yielded good agreements implying the reproducibility of the measurement to be constant (Table 3). Both calculated δ(18)O values relative to a given sample based on each observed δ(18)O value relative to two different samples agreed each other. It is concluded that the linearity of observed a-value holds over a range of 30‰ (Table 4).
Publication Title 岡山大学温泉研究所報告
Published Date 1972-03-25
Volume volume41
Start Page 3
End Page 7
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398147
JaLCDOI 10.18926/40148
Title Alternative The effect of pH of water on the measurement of oxygen isotopic ratio by means of CO(2)-H(2)O isotopic exchange technique
FullText URL pitsr_041_001_002.pdf
Author Matsubaya, Osamu|
Abstract The effect of pH of water on the measurement of oxygen isotopic ratio by means of CO(2)-H(2)O isotopic exchange technique was studied. In this study, a new type of reaction vessel was used (Fig. 1). The reaction time for equilibration using this new reaction vessel was nearly equal to that in the previous study (Fig. 2). The oxygen isotopic ratios of each two samples of pH 2, 4, 7, 8, 9, and 10 were measured. There is no significant difference between the observed δ(18)O values of these samples (Table 1). Therefore it is concluded that the effect of pH of water needs not to be taken into account on the measurement of oxygen isotopic ratio by means of CO(2)-H(2)O isotopic exchange technique.
Publication Title 岡山大学温泉研究所報告
Published Date 1972-03-25
Volume volume41
Start Page 1
End Page 2
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398148
Author 岡山大学温泉研究所|
Published Date 1972-03-25
Publication Title 岡山大学温泉研究所報告
Volume volume41
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1972-03-25
Publication Title 岡山大学温泉研究所報告
Volume volume41
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1973-03-25
Publication Title 岡山大学温泉研究所報告
Volume volume42
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1973-03-25
Publication Title 岡山大学温泉研究所報告
Volume volume42
Content Type Others
JaLCDOI 10.18926/40143
Title Alternative Rheumatoid arthritis and Sjögren's syndrome
FullText URL 042_031_045.pdf
Author Ichikawa, Yukinobu|
Abstract 1. Parotid Sialography Parotid sialograms were investigated in 29 patients with classical or definite RA according to the criteria of the American Rheumatism Association (one of whom had scleroderma), 5 patients with SLE (according to the Dubois's criteria, three were definite, one probable and another possible SLE), 3 patients with other autoimmune diseases (Hashimoto's thyroiditis, colitis ulcerosa and undiagnosed collagen disease), 3 patients with polyarthralgia and 10 patients with nonautoimmune diseases. Sialographic technique was performed by modified Rubin's Method using contrast medium Conray-400. Sialectasis which is pathognomonic of Sjögren's syndrome (SS) alone was observed in 6 patients with RA (20.7%) (3 punctate and 3 globular patterns) and 2 patients with SLE (one punctate and another globular pattern). Retention of the contrast medium in the duct for at least 5 minutes after the injection was observed in patients with RA, one patient with SLE and one patient with colitis ulcerosa. Sial ectasis and retention almost always existed together, and were observed in patients from young to older one. Although dilatation of the Stensen's duct and subalveolar dissection also existed together, they were observed in only older patients. It appeared that the former is the specific findings of SS and the latter is the non-specific findings according to the aging. Dry mouth was complained in 7 sialectasis (87.5%), 3 subalveolar dissection (60.0%), 10 retention (62.5%) and 9 normal sialogram (37.5%). Salivary hyposecretion (less than 10 ml/10min) was observed in 4 sialectasis (50%), one subalveolar dissection (20%), 6 dilatation of the Stensen's duct (37.5%), 5 retention (45.5%) and one normal sialogram (4.2%). These results show that sialectasis and retention are well correlated with salivary hyposecretion, but dry mouth is not so diagnostic in SS. Two patients with SLE had sialectasis were young women and showed normal salivary and lacrimal secretion. These cases may be supported by Heaton's hypothesis that SS is a benign and chronic form of SLE, or thay may be a subclinical state of SS. 2. Schirmer test Sixty seven patients (36RA, 6SLE, 3 other autoimmune diseases, 3 polyarthralgia and 19 non-autoimmune diseases) were examined by Schirmer test. Besides lacrimal hyposecretion was observed in RA and other autoimmune diseases, it began in younger age. These results show that autoimmune diseases have a sicca element in themselves. Compared with the results of sialography, Schirmer test was not correlated with sialectasis and retention. Dry eye was complained in only 4 patients (13.3%) with lacrimal hyposecretion (less than 10mm/5min) and all patients with dry eye had keratoconjunctivitis sicca (KCS). Dry eye is more diagnostic than Schirmer test. 3. Corneal staining by 1% rose bengal solution Twenty five patients with RA or SLE were examned corneal staining (Holm's type A) was observed in 5 patients with RA (20%). Staining of the medial and lateral bulbar conjunctiva (Holm's type B and C) were observed in 6 patients with RA (24%) and one patient with SLE. Nine patients with positive staining (type A, B and C) (75%) showed lacrimal hyposecretion. Dry eye was complained in 4 patients with type A staining (80%), but no patient with type B and C complained dry eye. Dry eye appears to be specific for the diagnosis of SS as sialectasis on the sialogram. 4. Salivary secretion All amount of saliva was collected during ten minutes chewing two pieces of gum. All of 21 patients with non-autoimmune diseases showed more than 10 ml/10min, and slight degree of salivary hyposecretion was observed with aging. Nine patients with RA (25.7%) showed salivary hyposecretion (less than 10ml/10min), besides it began in younger age. It was also observed in patients with other autoimmune diseases. Only 36.4% patients with salivary hyposecretion showed sialectasis on the sialogram. It can be supposed that patients with sialectasis and good salivary secretion are subclinical states of SS, and that this state is depends on the compensative function of the glands. Therefore, it is impossible to suppose the salivary dysfunction from the complaints of patients alone. It is required that saliva must be analysed not only quantitativly but also qualitativly (such as RA factor, complement and lysozome). Dry mouth was not only complained in 9 patients who showed salivary hyposecretion (81.8%). but in 10 patients showed normal secretion (50%). Dry mouth appears to be less specific for the diagnosis of SS than dry eye. 5. Diagnosis of SS Vanslow's criteria of SS was modified as follows. (1) Major : ① Sialectasis or salivary gland enlargement ② Positive corneal staining (type A) ③ Classical or definite RA (according to the criteria of the ARA) (2) Minor : ① Arthritis ② History ot salivary gland swelling ③ Dry mouth or salivary hyposecretion (less than 10ml/10min) ④ Dry eye or positive Schirmer test (less than 10mm/5min). Three major was diagnosed as definite, 2 major as probable and one major with one or more minor as possible SS. Of 35 patients with RA, definite (8.6%), probable (17.1%) and possible SS (54.3%) were obserevd. Two of SLE (33.3%) were possible SS. One patients with undiagnosed collagen disease was possible SS. Clinically, definite and probable SS may be diagnosed as Sjögren's syndrome. Two possible SS with SLE may be supporsed as subclinical states of SS who do not yet exhibite full criteria. Compared with the clinical and laboratory findings of these definite, probable and possible SS with RA, it was supporsed that positive antinuclear factor or positive LE cells in RA patients almost always represents SS, drug allergy, especially to gold therapy may be a manifestation of SS. Hypergammaglobulinemia, extreme elevation of erythrocyte sedimentation rate, struma, lymphnode enlargement in RA patients must be suspected of SS. Although one possible SS with SLE and one probable SS with RA showed positive ANF (peripheral pattern), it is impossible to differentiate SS from SLE by ANF alone. Because Suzuki et al. reported that 15.4% of SS had showed positive ANF (peripheral pattern). Examinations of salivary glands including sialography must be performed in patients with SLE in the future. To detect a subclinical SS, sialography and corneal staining must be performed even in patients with no sicca symptom, because of the compensatory functions of salivary and lacrimal glands.
Publication Title 岡山大学温泉研究所報告
Published Date 1973-03-25
Volume volume42
Start Page 31
End Page 45
ISSN 0369-7142
language Japanese
File Version publisher
NAID 40017532309
JaLCDOI 10.18926/40142
Title Alternative A case of systemic lupus erythematosus with idiopathic thrombocytopenic purpura
FullText URL pitsr_042_025_029.pdf
Author Ichikawa, Yukinobu| Ikegami, Tadaoki| Kitayama, Minoru| Morinaga, Hiroshi|
Abstract A 24-year-old woman was presented in whom thrombocytopenic purpura appeared during antiinflammatory drugs therapy for arthralgia. At that time she had a positive LE cell preparation, positive antinuclear factor and false positive serum test for syphilis. Steroid hormon and ACTH therapy were started under the diagnosis of systemic lupus erythematosus. In the 23-rd hospital days, she had a negative LE cell preparation, negative antinuclear factor and negative serum test for syphilis. In the 28-th days after stopping steroid hormon and ACTH therapy, positive LE cell preparation and positive antinuclear factor appeared again.
Publication Title 岡山大学温泉研究所報告
Published Date 1973-03-25
Volume volume42
Start Page 25
End Page 29
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398146
JaLCDOI 10.18926/40141
Title Alternative Preliminary experiments of electron probe X-ray microanalyzer (JXA5A)
FullText URL pitsr_042_009_023.pdf
Author Tazaki, Koichi| Hirano, Hideo|
Abstract Preliminary experiments on the accuracy of quantitative microprobe analysis for the instrument set in the Institute for Themal Spring Research, Okayama University were carried out. Dead time of the instrument ranged about 5.5-5.6 microsecond, which delayed 1.5 microsecond than usual value. Bombarding by finely focused electron beam, intensities of the characteristic X-ray of alkali metal such as NaKα and KKα decreased drastically in five to ten minutes. Intensities of the characteristic X-ray decreased in relation to the degree of off-focusing, when the spectrometer fixed at optically focused position. Readjusting of spectrometer after every move of sample was indispensable for the proof of accurate intensities. Applying BENCE and ALBEE'S correction method, empirical a factors was approved of preferable for quantitative analyses of silicates than calculated α factors.
Publication Title 岡山大学温泉研究所報告
Published Date 1973-03-25
Volume volume42
Start Page 9
End Page 23
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398145
JaLCDOI 10.18926/40140
Title Alternative Zoned alternation of gibbsite and clay mInerals in the vermicular gibbsite
FullText URL pitsr_042_001_007.pdf
Author Tazaki, Kazue|
Abstract Vermicular gibbsite aggregates found in the weathered pumice layer (the Kurayoshi pumice) at Yotsuzuka, western part of Tottori Prefecture, range in size from 5 to lOmm (Fig.1). They are more or less twisted and show some cleavages perpendicular to the long axis. Vermicular gibbsite are milky white colored and usually coated with dark brown color. X-ray diffraction patterns show strong renections for gibbsite, kaoline minerals, hydrobiotite and a relatively small amount of hydrated halloysite (Fig.3), Kaoline minerls are rather abundant at the white part. On the other hand, the dark brown part is rich in hydrobiotite. Differential thermal analysis shows the endothermic reaction for the dehydration of gibbsite at 310℃ and of kaoline minerals, hydrated halloysite and hydrobiotite at 550℃ (Fig.4). Electron microscopy shows that the gibbsite consist of peculiarly warped rods (Plate 1). The clay minerals which are looked like "cracked rice grain" are seemingly kaoline minerals or hydrated halloyslte. By the electron microprobe scanning across the vermicular gibbsite, the triform structure is revealed, such as the gibbsite rich part, the hydrobiotite rich part and kaoline minerals rich part (Fig.5 and 6). Gibbsite and clay minerals (hydrobiotite or kaoline minerals) grow alternately zone by zone (Fig.7). The width of each zone ranges in size from 20 to 40 micron.
Publication Title 岡山大学温泉研究所報告
Published Date 1973-03-25
Volume volume42
Start Page 1
End Page 7
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398144
Author 岡山大学温泉研究所|
Published Date 1973-03-25
Publication Title 岡山大学温泉研究所報告
Volume volume42
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1973-03-25
Publication Title 岡山大学温泉研究所報告
Volume volume42
Content Type Others