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JaLCDOI 10.18926/40177
Title Alternative Study on effects of balneotherapy on blood pH, P(CO(2)) and P(O(2)) Part I. Evaluation of measurement apparatus and methods of the proccedures
FullText URL pitsr_038_001_009.pdf
Author Yahata, Takaaki|
Abstract Human venous blood pH, P(CO(2)) and P(O(2)) were measured with I. L. Meter. Its reproducibility and response rate were evaluated as well as methods of the procedures. 1) Time required to reach the stability of pH, P(CO(2)), and P(O(2)) reading after the sampie injection was 1~1.5 min., 2~2.5 min. and 45~75 sec., respectively. It is recommended in the measurement of these parameters at the same time that the sample injection starts with P(CO(2)) electrode, followed by pH and P(O(2)) in this order and that readings are recorded in the order of pH, P(O(2)) and P(CO(2)). 2) Range of differences between the two values measured in the interval of 3~5 min. were pH : -0.010~0.020 (mean: 0.003), P(CO(2)) : -1.0~1.0mmHg (mean: 0.4) and P(O(2)) : -1.0~0.0mmHg (mean: -0.5). Their 5% rejection limits were 0.021≧x(o)≧-0.015, 2.0≧x(o)≧-1.2mmHg and 0.3≧x(o)≧-1.3mmHg, respectively. 3) The pH, P(CO(2)) and P(O(2)) of the heparinized venous blood stored in ice water showed no significant changes in 60 min. and they gave practically the same results as the measurement just after shedding.
Publication Title 岡山大学温泉研究所報告
Published Date 1969-03-20
Volume volume38
Start Page 1
End Page 9
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398499
Author 岡山大学温泉研究所|
Published Date 1969-03-20
Publication Title 岡山大学温泉研究所報告
Volume volume38
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1970-03-30
Publication Title 岡山大学温泉研究所報告
Volume volume39
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1970-03-30
Publication Title 岡山大学温泉研究所報告
Volume volume39
Content Type Others
JaLCDOI 10.18926/40173
Title Alternative Follow-up results of rheumatic disorders treated with hot springs
FullText URL pitsr_039_077_080.pdf
Author Matsumoto, Kinshi|
Abstract Misasa Spa, located in Tottori Prefecture, was discovered in 1164, and it has been widely used for the management of rheumatic disorders, gastrointestinal diseases and so on. In 1914, Dr. R. ISHIZU measured radon contents in Misasa spring waters to be 142.14 Mache, and then Misasa Hot Springs, alkaline common salt springs, were also known as radioactive hot springs. In July, 1958, patients with rheumatic complaints who had balneotherapy at Misasa Branch Hospital of Okayama University, from January, 1955 to March, 1958, were reexamined. A questionnaire about the effectiveness of balneotherapy was sent to 149 patients and 98 answers were received. The results were as follows: 1. Spa treatment was effective in 100% of shoulder-hand syndrome and osteo-arthrosis of the knee, in 95% of degenerative spondylosis, in 93% of rheumatoid arthritis, in 80% of low back pain, in 67% of sciatica, etc. Generally speaking, balneotherapy was effectual in 78 of 98 patients with rheumatic disorders (81.2%). 2. The effectiveness of spa treatment came out in the course of thermal cure in 74% of 78 cases, and the others recognized the effects after spa treatment was finished. 3. The effect of spa therapy on the subjective complaints was notable in the cases which had a period of spa treatment over half a month. In the cases which had a period of spa treatment within 2 weeks, it is thought that the period is too short to reveal the efficacy of hot spring bathing. 4. It appeared that drinking of hot spring water had no remarkable effect on rheumatic complaints. 5. Forty-three per cent of the cases answered that their body conditions during this inquiry time became better than that at the beginning of the balneotherapy, and the remainders of the reexamined cases were under the trcatments with cortisone, vitamine, massage, acupuncture and so forth.
Publication Title 岡山大学温泉研究所報告
Published Date 1970-03-30
Volume volume39
Start Page 77
End Page 80
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398498
JaLCDOI 10.18926/40172
Title Alternative The effect of radioaclive thermal bathing upon serum iron values
FullText URL 039_061_075.pdf
Author Yamamoto, Yasuhisa|
Abstract The author investigated the effect of radioactive hot spring bathing on serum iron values. The serum iron values were measured by Umemoto-Yamamoto's method using o-nitrosoresorcin monomethylether, as a colour-developing reagent. The chemical compositions of the spring water used is as following: pH : 7.04, Rn : 38-151x10(-10)curies/l, K(+) : 14.0, Na(+) : 540.2, Ca(++) : 61. 2, Mg(++) : 6.6, Fe(++) : 89.0, AI(+++) : 0.1, Cl(-) : 709.5, S0(4)(--) : 179.5, HCO(3)(-) : 226.7, H(2)SiO(3) : 89.0, HBO(2) : +, CO(2) : 29.5, totaling 1,827mg/kg. 1) Single bathing: The iron values in the serum were measured before and after 0, 1/2, 1 and 2 hours after the radioactive thermal bathing for 10 minutes in water of 41 ±2℃ in temperature. Single thermal bathing showed no significant effect on the serum iron values in healthy hnman subjects, but the serum iron concent:'ations in healthy white rabbits tended to decrease following single thermal bathing and to remain at a decreased level for 1/2 to 1 hour, and returned to normally within 2 hours from the time of the bathing (Table 1, 2 and Fig. 1, 2). 2) A series of baths: The author examined the serum iron values of patients with rheumatic disorders before and 3rd, 7th, 14th, 21st and 28th days after in the course of "a series of baths" in radioactive hot spring. Patients bathed in water of 41 ± 2℃ in temperature, for 5-10 minutes, 2 or 3 times daily. A fall in the serum iron values was seen on the 3rd to 7th days. At that time the pattern of iron absorption from intestine showed a iron dificiency anemia type. The rate of absorption of iron was rapid. At about the 14th day, the serum iron values of patients tended to increase but unbound iron-binding capacity of the serum decreased. Subsequently, the serum iron values returned to the initial levels between the 21st and 28th day (Table 3, 4, 5, and Fig. 3, 4, 5), 3) It is said that the reticulo-endothelial system plays an inportant part in iron metabolism. The author injected 5 ml of Indian ink into the aural vein of rabbits for the purpose of blocking the reticulo-endothelial system. These procedures were carried out once a day for 7 successive days. The rabbits with "a blockade of R. E. S." had no significant change in the serum iron values during a series of baths. From what has been stated in the above, it may be said that bathing in radioactive hot springs regubtes the iron metabolism of patients with anemia and brings about the acceleration of the medullary function.
Publication Title 岡山大学温泉研究所報告
Published Date 1970-03-30
Volume volume39
Start Page 61
End Page 75
ISSN 0369-7142
language Japanese
File Version publisher
NAID 40017532352
Author Inoue, Taeko| Ikegami, Tadaoki| Morinaga, Hiroshi|
Published Date 1970-03-30
Publication Title 岡山大学温泉研究所報告
Volume volume39
Content Type Data or Dataset
JaLCDOI 10.18926/40170
Title Alternative Study on the conbined therapy of spa and gold salt in rheumatoid arthritis Part II. An experience of granulocytopenia possibly caused by gold salt preparation
FullText URL pitsr_039_037_042.pdf
Author Ikegami, Tadaoki| Yahata, Takaaki| Kitayama, Minoru| Morinaga, Hiroshi|
Abstract A thirty seven years old woman with rheumatoid arthritis was instituted gold salt intramuscularly twice a week on the nineteenth hospital day. On the fifty fourth day, however, it was discontinued at the total dosis of 180 mg because of the skin rush. In about ten days after stopping gold injection appeared high fever with shivering and granulocytopenia was demonstrated. With immediate administration of ACTH, adrenocortical hormons etc. including blood transfusion the abnormal findings of the blood pictures returned to normal and the patient became well. Recently, gold salts are so widely used in treatment of rheumatoid arthritis as one of specific antirheumatic agents that the possible severe side effect such as granulocytopenia, if quite rare, should always be considered in the course of gold therapy.
Publication Title 岡山大学温泉研究所報告
Published Date 1970-03-30
Volume volume39
Start Page 13
End Page 35
ISSN 0369-7142
language Japanese
File Version publisher
JaLCDOI 10.18926/40169
Title Alternative Clinical studies on electromyographic changes in rheumatoid arthritis Part II. Electromyographic changes in treated rheumatoid arthritis during 3 months after admission
FullText URL 039_013_035.pdf
Author Ikegami, Tadaoki|
Abstract Electromyograms were recorded on 15 patients with rheumatoid arthritis (12 cases of classical rheumatoid arthritis and 3 cases of definite rheumatoid arthritis) and 5 cases of healthy controls. The muscles selected were the biceps brachii, opponens pollicis and abductor pollieis brevis, and following results were obtained: 1) The amplitude and mean potential duration in rheumatoid arthritis were less than controls, the differences being statistically significant. 2) Electromyographic evidence of myogenic atrophy was demonstrated in the small hand muscles and proximal muscles. 3) Myogenic atrophy due to steroid therapy was considered in proximal muscles, while the small hand muscles were affected more rarely. 4) Myogenic atrophy in stage III-IV were less than those in stage I-II, but in the m. opponens pollicis there were little differences. 5) Myogenic atrophy in inactive rheumatoid arthritis were significantly less than those in active, but in the m. opponens pollicis no marked changes were observed. 6) Myogenic atrophy of the m. opponens pollicis were more than that of m. abductor pollicis brevis.
Publication Title 岡山大学温泉研究所報告
Published Date 1970-03-30
Volume volume39
Start Page 13
End Page 35
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398497
JaLCDOI 10.18926/40168
Title Alternative Clinical studies on electromyographic changes in rheumatoid arthritis Part I. Electromyographic changes in rheumatoid arthritis
FullText URL pitsr_039_001_012.pdf
Author Ikegami, Tadaoki|
Abstract Electromyograms were recorded on 15 patients with rheumatoid arthritis (12 cases of classical rheumatoid arthritis and 3 cases of definite rheumatoid arthritis) and 5 cases of healthy controls. The muscles selected were the biceps brachii, opponens pollicis and abductor pollieis brevis, and following results were obtained: 1) The amplitude and mean potential duration in rheumatoid arthritis were less than controls, the differences being statistically significant. 2) Electromyographic evidence of myogenic atrophy was demonstrated in the small hand muscles and proximal muscles. 3) Myogenic atrophy due to steroid therapy was considered in proximal muscles, while the small hand muscles were affected more rarely. 4) Myogenic atrophy in stage III - IV were less than those in stage I·II, but in the m. opponens pollicis there were little differences. 5) Myogenic atrophy in inactive rheumatoid arthritis were significantly less than those in active, but in the m. opponens pollicis no marked changes were observed. 6) Myogenic atrophy of the m. opponens pollicis were more than that of m. abductor pollicis brevis.
Publication Title 岡山大学温泉研究所報告
Published Date 1970-03-30
Volume volume39
Start Page 1
End Page 12
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398496
Author 岡山大学温泉研究所|
Published Date 1970-03-30
Publication Title 岡山大学温泉研究所報告
Volume volume39
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1970-03-30
Publication Title 岡山大学温泉研究所報告
Volume volume39
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1971-03-26
Publication Title 岡山大学温泉研究所報告
Volume volume40
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1971-03-26
Publication Title 岡山大学温泉研究所報告
Volume volume40
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1971-03-26
Publication Title 岡山大学温泉研究所報告
Volume volume40
Content Type Others
JaLCDOI 10.18926/40162
Title Alternative Isotopic study of Hot Springs in Japan, I Techniques for oxygen isotopic analysis of spring water
FullText URL pitsr_040_033_040.pdf
Author Matsubaya, Osamu| Sakai, Hitoshi| Tanaka, Hinako| Uemura, Tazue|
Abstract The CO(2)-H(2)O isotopic equilibration technique was studied for the routine analyses of the oxygen isotopic ratios of hot spring water. A reaction vessel containing 2 ml of water and 0.16 m mole of tank CO(2) was shaken for 18 hrs. in a constant-temperature bath at 25.0℃ (Figs. 1, 2, and 3), and the CO(2) was analyzed for the oxygen isotopic ratio by a MCKINNEY type mass spectrometer. Several aliquots of 1, 2 and 5 ml from a same water were each analyzed three times by successive equilibration (Table 1). The observed values differ depending on the volume of water but the corrected values by equation (6) indicate excellent agreement, implying the whole processes to be well controlled. The reproducibility of the isotopic analyses is better than ± 0.1‰ (Table 2) in most cases, and the accuracy would not be worse than ± 0.2‰ as demonstrated by the interlaboratory comparison of some standard samples (Table 3). Oxygen isotopic ratios of water from more than 70 hot springs in Japan are presented (Table 5). Although the results will be discussed in the following issues of this series of paper, most hot spring water have the δ(18)O values similar to those of meteoric waters in Japan. However, spring water from Arima Hot Springs, Hyogo-Pref., which has been known by its abnormally high chloride and low sulfate concentrations is of an exceptionally high δ(18)O value.
Publication Title 岡山大学温泉研究所報告
Published Date 1971-03-26
Volume volume40
Start Page 33
End Page 40
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398154
JaLCDOI 10.18926/40161
Title Alternative Studies on the uptake of (75)Se-selenomethionine by the pancreas Attempt to augment by the effects of protocols
FullText URL pitsr_040_019_031.pdf
Author Tokunou, Tsuneo|
Abstract Since the introduction of the pancreatic scanning using (75)Se-selenomethionine, there has been various protocols proposed to increase the pancreatic uptake of this isotope. In this experiment several protocols; as diets high carbohydrate meal, high protein meal, high fat meal, and as medicaments pancreozymin, secretin and phydroxyphenylsalicylamide (PHPS), were tested for determining the effects on the uptake of (75)Se-selenomethionine by the pancreas and the liver of the dog. The animals given protocols were sacrified at each of a number of selected times to compare P/L ratio on a percentper-gram concentration of (75)Se-selenomethionine and the total organ concentration of (75)Se-selenomethionine in the pancreas and in the liver. A controlled group of animals were fasted for 24-hour and sacrificed at each of same times. On P/L ratio basis it was found that animals with high carbohydrate meal had better ratio than those with no preparation during first 4-hour post administration. However, animals with each of high protein meal. fat meal and PI-IPS had lower ratio than those with no preparation. On the blood concentration, animals with each of high carbohydrate meal and secretin had lower variation of blood concentration than controlled group. Thus, from the results mentioned above, the protocol by high carbohydrate meal is proved to be useful in pancreatic scanning.
Publication Title 岡山大学温泉研究所報告
Published Date 1971-03-26
Volume volume40
Start Page 19
End Page 31
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398153
JaLCDOI 10.18926/40160
Title Alternative Clinical studies on electromyographic changes in rheumatoid arthritis Part III. Effect of radioactive hot spring baths
FullText URL pitsr_040_001_017.pdf
Author Ikegami, Tadaoki|
Abstract The author observed the changes in electromyographic patterns of 14 patients with rheumatoid arthritis (13 cases of classical rheumatoid arthritis and one case of definite rheumatoid arthritis) bathed 2 or 3 times daily in hot spring water at Misasa Spa, at a temperature of 40±1℃, 5-10 minutes. The electromyographic examination was performed on the biceps brachii, opponens pollicis and the abductor pollicis brevis. Intramuscular temperature was measured in the deltoid muscle. The results were as follows. 1) The intramuscular temperature in cases of rheumatoid arthritis did not deviate from normal subjects. 2) After the general spring bathing the intramuscular temperature increased about 1℃ and it had no difference between the patients with rheumatoid arthritis and normal subjects. 3) With increasing intramuscular temperature by the general spring bathing in cases of active rheumatoid arthritis the mean potential amplitude decreased and the mean potential duration increased. 4) With increasing intramuscular temperature by the general spring bathing in cases of inactive rheumatiod arthritis the mean amplitude increased and the mean duration decreased. 5) The patterns of potential duration and amplitude before and after a bath on re-examination, one month after a series of the general spring baths, showed a tendency of reverse of the initial patterns. 6) After two months of a series of the general spring baths, the patterns of electromyographic changes of patients with rheumatoid arthritis following the bathing were similar to the initial patterns.
Publication Title 岡山大学温泉研究所報告
Published Date 1971-03-26
Volume volume40
Start Page 1
End Page 17
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002398152
Author 岡山大学温泉研究所|
Published Date 1971-03-26
Publication Title 岡山大学温泉研究所報告
Volume volume40
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1971-03-26
Publication Title 岡山大学温泉研究所報告
Volume volume40
Content Type Others