result 4380 件
| FullText URL | tetrahed_lett_59_11_955.pdf |
|---|---|
| Author | Takamura, Hiroyoshi| |
| Keywords | Natural product Stereodivergent synthesis Stereodiversification Stereoisomer |
| Published Date | 2018-02-10 |
| Publication Title | Tetrahedron Letters |
| Volume | volume59 |
| Issue | issue11 |
| Publisher | Pergamon Press |
| Start Page | 955 |
| End Page | 966 |
| ISSN | 00404039 |
| NCID | AA00861801 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| DOI | 10.1016/j.tetlet.2018.02.004 |
| Web of Science KeyUT | 000427217400001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.tetlet.2018.02.004 |
| JaLCDOI | 10.18926/AMO/56655 |
|---|---|
| FullText URL | 73_2_181.pdf |
| Author | Okamura, Tomoka| Washio, Yousuke| Yoshimoto, Junko| Tani, Kazumasa| Tsukahara, Hirokazu| Shimada, Akira| |
| Abstract | Most cases of transient abnormal myelopoiesis (TAM) in neonates with Down syndrome (DS) resolve spontaneously; however, DS-TAM neonates with hydrops fetalis (HF) show poor clinical outcomes. We report three infants with DS-TAM and HF who were treated with exchange transfusion (ET) followed by low-dose cytarabine (LD-CA). All of them survived without developing liver failure, acute leukemia, or other serious adverse events. Our results suggest that this combination treatment with ET and LD-CA would be safe, tolerable and effective as an novel approach for DS-TAM patients with HF. |
| Keywords | cytarabine Down syndrome exchange transfusion hydrops fetalis transient abnormal myelopoiesis |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-04 |
| Volume | volume73 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 181 |
| End Page | 188 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31015754 |
| JaLCDOI | 10.18926/AMO/56654 |
|---|---|
| FullText URL | 73_2_177.pdf |
| Author | Okita, Atsushi| Ohtani, Jun| |
| Abstract | We report a rare case of fistulation to the jejunum after percutaneous endoscopic gastrostomy (PEG). An 85-year-old man with previous cerebral infarction and swallowing disturbance underwent PEG. Nine months later, he developed a high fever and discharge around the gastrostomy button. He was diagnosed with aspiration pneumonia, and administered antibiotic therapy. Examination showed digestive fluid around the gastrostomy button. Gastrointestinal contrast-enhanced CT revealed a gastrojejunocutaneous fistula. The button was removed, and the fistula closed naturally. PEG was performed again. The patient’s postoperative course was uneventful. Gastrojejunocutaneous fistula should be considered in cases involving increased discharge from a gastrostomy fistula. |
| Keywords | percutaneous endoscopic gastrostomy gastrojejunocutaneous fistula |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-04 |
| Volume | volume73 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 177 |
| End Page | 180 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31015753 |
| JaLCDOI | 10.18926/AMO/56649 |
|---|---|
| FullText URL | 73_2_135.pdf |
| Author | Maeba, Takahiro| Yonezawa, Tomoko| Ono, Mitsuaki| Tomono, Yasuko| Heljasvaara, Ritva| Pihlajaniemi, Taina| Inagawa, Kiichi| Oohashi, Toshitaka| |
| Abstract | The basement membrane (BM) is composed of various extracellular molecules and regulates tissue regeneration and maintenance. Here, we demonstrate that collagen XVIII was spatiotemporally expressed in the BM during skin wound healing in a mouse excisional wound-splinting model. Re-epithelialization was detected at days 3 and 6 post-wounding. The ultrastructure of epidermal BM was discontinuous at day 3, whereas on day 6 a continuous BM was observed in the region proximal to the wound edge. Immunohistochemistry demonstrated that collagen XVIII was deposited in the BM zone beneath newly forming epidermis in day 3 and 6 wounds. Laminin-332, known to be the earliest BM component appearing in wounds, was colocalized with collagen XVIII in the epidermal BM zone at days 3 and 6. The deposition of α1(IV) collagen and nidogen-1 in the epidermal BM zone occurred later than that of collagen XVIII. We also observed the short isoform of collagen XVIII in the epidermal BM zone at day 3 post-wounding. Collectively, our results suggested that collagen XVIII plays a role in the formation of the dermal-epidermal junction during re-epithelialization, and that it is the short isoform that is involved in the early phase of re-epithelialization. |
| Keywords | collagen XVIII basement membrane wound healing re-epithelialization skin |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-04 |
| Volume | volume73 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 135 |
| End Page | 146 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 31015748 |
| JaLCDOI | 10.18926/AMO/56464 |
|---|---|
| FullText URL | 73_1_85.pdf |
| Author | Abe, Yoshiyuki| Fujibayashi, Kazutoshi| Nishizaki, Yuji| Yanagisawa, Naotake| Nojiri, Shuko| Nakano, Soichiro| Tada, Kurisu| Yamaji, Ken| Tamura, Naoto| |
| Abstract | Pneumocystis pneumonia (PCP) due to Pneumocystis jirovecii infection is the leading cause of fatal opportunistic infections in immunocompromised patients. We will determine whether a daily sulfamethoxazole-trimethoprim (SMX/TMP) dose of 200/40 mg was non-inferior to 400/80 mg for PCP prevention in patients with systemic rheumatic disease under immunosuppressive therapy. This is a randomized, open-label, multicenter controlled trial. The primary outcome is the rate of PCP prevention at 52 weeks. The secondary outcome is the discontinuation rate of SMX/TMP. The trial will evaluate the optimal dose of SMX/TMP for PCP prevention in patients with systemic rheumatic disease under immunosuppressive therapy. |
| Keywords | pneumocystis pneumonia prophylaxis systemic rheumatic disease sulfamethoxazole-trimethoprim conventional-dose versus half-dose |
| Amo Type | Clinical Study Protocol |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-02 |
| Volume | volume73 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 85 |
| End Page | 89 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 30820060 |
| JaLCDOI | 10.18926/AMO/56458 |
|---|---|
| FullText URL | 73_1_51.pdf |
| Author | Fujii, Masakuni| Fujimoto, Kenji| Yabe, Syuntaro| Nasu, Junichiro| Miyaike, Jiro| Yoshioka, Masao| Shiode, Junji| Yamamoto, Kazuhide| Matsuda, Shinya| |
| Abstract | We investigated the relationship between body mass index (BMI) and postoperative outcomes in 450 gallbladder cancer patients in Japan. We collected patient information, including sex, age, underlying disease, BMI, stage, surgery method, postoperative time to discharge, and postoperative Medicare fees, from the Japanese administrative database associated with the Diagnosis Procedure Combination system. We classified patient BMIs as underweight (BMI<18.5 kg/m2), normal (BMI≥18.5 kg/m2 and <25 kg/m2) or overweight/obese (BMI≥25 kg/m2), then investigated the relationship between these categories and two postoperative outcomes: time to discharge and postoperative Medicare fees. The median postoperative time to discharge was 12 days in all patients, and 12 days in each of the three weight groups (p=0.62, n.s.). The median postoperative Medicare fees from surgery until discharge were (USD): all patients, $5,002; underweight, $5,875; normal weight, $4,797; and overweight/obese, $5,179 (p=0.146, n.s.). A multivariate analysis with adjustment for competing risk factors revealed that BMI was not associated with increased risk of longer postoperative time to discharge (normal weight: HR 1.17, p=0.29; overweight/obese: HR 1.17, p=0.37) or higher postoperative Medicare fees (OR 0.99, p=0.86, n.s.). Thus, high BMI was not found to be a factor for poor postoperative outcomes in Japanese patients with gallbladder cancer. |
| Keywords | body mass index gallbladder cancer surgery obesity |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2019-02 |
| Volume | volume73 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 51 |
| End Page | 59 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2019 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 30820054 |
| FullText URL | OJE_2019021915240510.pdf |
|---|---|
| Author | Kato, Sadahisa| Hishiyama, Kosuke| Anak Agung Ketut Darmadi| Ngakan Ketut Acwin Dwijendra| Dewa Ngurah Suprapta| |
| Keywords | Telajakan Bali Urban Green Spaces |
| Published Date | 2019-02-20 |
| Publication Title | Open Journal of Ecology |
| Volume | volume9 |
| Publisher | Scientific Research Publishing |
| Start Page | 15 |
| End Page | 24 |
| ISSN | 2162-1993 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | http://creativecommons.org/licenses/by/4.0/ |
| File Version | publisher |
| DOI | 10.4236/oje.2019.92002 |
| Related Url | isVersionOf https://doi.org/10.4236/oje.2019.92002 |
| FullText URL | IPSJ-Z79-7Q-08.pdf |
|---|---|
| Author | 河村 一希| Takeuchi, Koichi| |
| Published Date | 2017-03 |
| Publication Title | 情報処理学会全国大会講演論文集 |
| Volume | volume79 |
| Publisher | 情報処理学会 |
| Start Page | 607 |
| End Page | 608 |
| NCID | AN00349328 |
| Content Type | Conference Paper |
| language | Japanese |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | copyright(c)Information Processing Society of Japan |
| File Version | publisher |
| FullText URL | IPSJ-Z79-7Q-04.pdf |
|---|---|
| Author | 宮田 周| Takeuchi, Koichi| |
| Published Date | 2017-03 |
| Publication Title | 情報処理学会全国大会講演論文集 |
| Volume | volume79 |
| Publisher | 情報処理学会 |
| Start Page | 599 |
| End Page | 600 |
| NCID | AN00349328 |
| Content Type | Conference Paper |
| language | Japanese |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | copyright(c)Information Processing Society of Japan |
| File Version | publisher |
| FullText URL | Association_Natural_Language_Processing_2017.pdf |
|---|---|
| Author | Takeuchi, Koichi| 大野 雅幸| 泉仁 宏太| Taguchi, Masahiro| Inada, Yoshihiko| Iizuka, Masaya| Abo, Tatsuhiko| Ueda, Hitoshi| |
| Published Date | 2017-03 |
| Publication Title | 言語処理学会年次大会発表論文集 |
| Volume | volume23 |
| Publisher | 言語処理学会 |
| Start Page | 839 |
| End Page | 842 |
| NCID | AA11909127 |
| Content Type | Conference Paper |
| language | Japanese |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| FullText URL | Association_Natural_Language_Processing_2018.pdf |
|---|---|
| Author | Ohno, Masayuki| 泉仁 宏太| Takeuchi, Koichi| 小畑 友也| Taguchi, Masahiro| Inada, Yoshihiko| Iizuka, Masaya| 阿保 達彦| 上田 均| |
| Published Date | 2018-03 |
| Publication Title | 言語処理学会年次大会発表論文集 |
| Volume | volume24 |
| Publisher | 言語処理学会 |
| Start Page | 368 |
| End Page | 371 |
| NCID | AA11909127 |
| Content Type | Conference Paper |
| language | Japanese |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| Title Alternative | Proposing an Unsupervised Approach to Evaluate Essays Using IDF on Reference Data |
|---|---|
| FullText URL | NLC2018-33.pdf |
| Author | Ohno, Masayuki| Takeuchi, Koichi| Motojin, Kota| Obata, Yuya| Taguchi, Masahiro| Inada, Yoshihiko| Iizuka, Masaya| Abo, Tatsuhiko| Ueda, Hitoshi| |
| Keywords | 自動採点 (automatic scoring of essays) アノテーション (human annotation) 採点支援 (supporting system of essay evaluation) idf neologd |
| Published Date | 2018-12 |
| Publication Title | IEICE technical report. Natural language processing and models of communication |
| Volume | volume118 |
| Issue | issue355 |
| Publisher | 電子情報通信学会 |
| Start Page | 103 |
| End Page | 108 |
| ISSN | 09135685 |
| NCID | AA11524632 |
| Content Type | Journal Article |
| language | Japanese |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | copyright@2018 |
| File Version | publisher |
| Title Alternative | A Study of Extracting Related Documents for Essay Evaluation Modules |
|---|---|
| FullText URL | NLC2017-24.pdf |
| Author | Motojin, Kota| Takeuchi, Koichi| Ohno, Masayuki| Taguchi, Masahiro| Inada, Yoshihiko| Iizuka, Masaya| Abo, Tatsuhiko| Ueda, Hitoshi| |
| Keywords | 小論文の自動採点 (Automatic scoring of answers of essay-writing tests) 単語ベクトル (Word vector) Skip-gram Wikipedia |
| Published Date | 2017-09 |
| Publication Title | IEICE technical report. Natural language processing and models of communication |
| Volume | volume117 |
| Issue | issue207 |
| Publisher | 電子情報通信学会 |
| Start Page | 47 |
| End Page | 51 |
| ISSN | 09135685 |
| NCID | AA11524632 |
| Content Type | Journal Article |
| language | Japanese |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | copyright©2017 IEICE |
| File Version | publisher |
| FullText URL | Nat_Plants_4_1044.pdf |
|---|---|
| Author | Takami, Tsuneaki| Ohnishi, Norikazu| Kurita, Yuko| Iwamura, Shoko| Ohnishi, Miwa| Kusaba, Makoto| Mimura, Tetsuro| Sakamoto, Wataru| |
| Note | This is an Accepted Manuscript of an article published by Springer Nature Publishing AG| |
| Published Date | 2018-05-12 |
| Publication Title | Nature Plants |
| Volume | volume4 |
| Publisher | Springer Nature Publishing AG |
| Start Page | 1044 |
| End Page | 1055 |
| ISSN | 20550278 |
| NCID | AA1273934X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 30420711 |
| DOI | 10.1038/s41477-018-0291-x |
| Related Url | isVersionOf https://doi.org/10.1038/s41477-018-0291-x |
| FullText URL | Geochem_Cosmochi_Act_235_76.pdf |
|---|---|
| Author | Inoue, Mayuri| Nakamura, Takashi| Tanaka, Yasuaki| Suzuki, Atsushi| Yokoyama, Yusuke| Kawahata, Hodaka| Sakai, Kazuhiko| Gussone, Nikolaus| |
| Keywords | Coral symbiosis calcification pH geochemical tracers |
| Note | This is an Accepted Manuscript of an article published by Elsevier B.V.| |
| Published Date | 2018-08-15 |
| Publication Title | Geochimica et Cosmochimica Acta |
| Volume | volume235 |
| Publisher | Elsevier B.V. |
| Start Page | 76 |
| End Page | 88 |
| ISSN | 00167037 |
| NCID | AA00655038 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| DOI | 10.1016/j.gca.2018.05.016 |
| Related Url | isVersionOf https://doi.org/10.1016/j.gca.2018.05.016 |
| JaLCDOI | 10.18926/AMO/56370 |
|---|---|
| FullText URL | 72_6_539.pdf |
| Author | Hiraki, Takao| Kamegawa, Tetsushi| Matsuno, Takayuki| Komaki, Toshiyuki| Sakurai, Jun| Kanazawa, Susumu| |
| Abstract | Since 2012, we have been developing a remote-controlled robotic system (Zerobot®) for needle insertion during computed tomography (CT)-guided interventional procedures, such as ablation, biopsy, and drainage. The system was designed via a collaboration between the medical and engineering departments at Okayama University, including various risk control features. It consists of a robot with 6 degrees of freedom that is manipulated using an operation interface to perform needle insertions under CT-guidance. The procedure includes robot positioning, needle targeting, and needle insertion. Phantom experiments have indicated that robotic insertion is equivalent in accuracy to manual insertion, without physician radiation exposure. Animal experiments have revealed that robotic insertion of biopsy introducer needles and various ablation needles is safe and accurate in vivo. The first in vivo human trial, therefore, began in April 2018. After its completion, a larger clinical study will be conducted for commercialization of the robot. This robotic procedure has many potential advantages over a manual procedure: 1) decreased physician fatigue; 2) stable and accurate needle posture without tremor; 3) procedure automation; 4) less experience required for proficiency in needle insertion skills; 5) decreased variance in technical skills among physicians; and 6) increased likelihood of performing the procedure at remote hospitals (i.e., telemedicine). |
| Keywords | robot needle insertion CT-guided interventional radiology |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-12 |
| Volume | volume72 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 539 |
| End Page | 546 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 30573907 |
| NAID | 120006545155 |
| FullText URL | PhysRevB_97_064425.pdf |
|---|---|
| Author | Horigane, Kazumasa| Fujii, M.| Okabe, H.| Kobayashi, K.| Horie, R.| Ishii, H.| Liao, Y. F.| Kubozono, Y.| Koda, A.| Kadono, R.| Akimitsu, J.| |
| Note | This is an article published by American Physical Society| |
| Published Date | 2018-02-28 |
| Publication Title | Physical Review B |
| Volume | volume97 |
| Publisher | American Physical Society |
| Start Page | 064425 |
| ISSN | 2469-9950 |
| NCID | AA11187113 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| DOI | 10.1103/PhysRevB.97.064425 |
| Web of Science KeyUT | 000426321000005 |
| Related Url | isVersionOf https://doi.org/10.1103/PhysRevB.97.064425 |
| FullText URL | Nature_556_209.pdf |
|---|---|
| Author | Yu, Long-Jiang| Suga, Michihiro| Wang-Otomo, Zheng-Yu| Shen, Jian-Ren| |
| Note | This is an Accepted Manuscript of an article published by Springer Nature| |
| Published Date | 2018-04-04 |
| Publication Title | Nature |
| Volume | volume556 |
| Publisher | Springer Nature |
| Start Page | 209 |
| End Page | 213 |
| ISSN | 0028-0836 |
| NCID | AA00752384 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 29618814 |
| DOI | 10.1038/s41586-018-0002-9 |
| Web of Science KeyUT | 000430082000040 |
| Related Url | isVersionOf https://doi.org/10.1038/s41586-018-0002-9 |
| FullText URL | Nat_Comm_9_2132.pdf |
|---|---|
| Author | Nishimura, Noriyuki| Tsuchiya, Wataru| Moresco, James J.| Hayashi, Yuki| Satoh, Kouji| Kaiwa, Nahomi| Irisa, Tomoko| Kinoshita, Toshinori| Schroeder, Julian I.| Yates III, John R.| Hirayama, Takashi| Yamazaki, Toshimasa| |
| Published Date | 2018-06-06 |
| Publication Title | Nature Communications |
| Volume | volume9 |
| Publisher | Springer Nature |
| Start Page | 2132 |
| ISSN | 2041-1723 |
| NCID | AA12645905 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| PubMed ID | 29875377 |
| DOI | 10.1038/s41467-018-04437-9 |
| Related Url | isVersionOf https://doi.org/10.1038/s41467-018-04437-9 |
| FullText URL | O0004493_abstract_review.pdf O0004493_summary.pdf |
|---|---|
| Author | Onishi, Yuji| |
| Published Date | 2018-09-27 |
| Content Type | Thesis or Dissertation |
| Grant Number | 乙第4493号 |
| Granted Date | 2018-09-27 |
| Thesis Type | Doctor of Philosophy in Science |
| Grantor | 岡山大学 |
| language | Japanese |
