result 47942 件
| FullText URL | fulltext20230619-06.pdf |
|---|---|
| Author | Sone, Sota| Miyatake, Takahisa| |
| Keywords | Behavior LED Light response Photoresponse Red flour beetle Stored insects |
| Note | The version of record of this article, first published in Applied Entomology and Zoology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s13355-023-00829-6| |
| Published Date | 2023-06-07 |
| Publication Title | Applied Entomology and Zoology |
| Volume | volume58 |
| Issue | issue3 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 257 |
| End Page | 263 |
| ISSN | 0003-6862 |
| NCID | AA00543238 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| DOI | 10.1007/s13355-023-00829-6 |
| Web of Science KeyUT | 001003129000001 |
| Related Url | isVersionOf https://doi.org/10.1007/s13355-023-00829-6 |
| FullText URL | fulltext20230619-05.pdf |
|---|---|
| Author | Imajo, Satoshi| Tanabe, Yoshinori| Nakamura, Nobue| Honda, Mitsugi| Kuroda, Masahiro| |
| Keywords | panoramic radiography quantitative evaluation deformable image registration peak signal-to-noise ratio |
| Published Date | 2023-05-04 |
| Publication Title | Polish Journal of Medical Physics and Engineering |
| Volume | volume29 |
| Issue | issue2 |
| Publisher | Sciendo |
| Start Page | 85 |
| End Page | 91 |
| ISSN | 1898-0309 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Satoshi Imajo et al. |
| File Version | publisher |
| DOI | 10.2478/pjmpe-2023-0010 |
| Web of Science KeyUT | 000981963000001 |
| Related Url | isVersionOf https://doi.org/10.2478/pjmpe-2023-0010 |
| FullText URL | fulltext20230619-04.pdf |
|---|---|
| Author | Tsuneishi, Taichi| Kojima, Keiichi| Kubota, Fumika| Harashima, Hideyoshi| Yamada, Yuma| Sudo, Yuki| |
| Published Date | 2023 |
| Publication Title | Chemical Communications |
| Volume | volume59 |
| Issue | issue49 |
| Publisher | Royal Society of Chemistry (RSC) |
| Start Page | 7591 |
| End Page | 7594 |
| ISSN | 1359-7345 |
| NCID | AA11071130 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Royal Society of Chemistry 2023 |
| File Version | publisher |
| PubMed ID | 37254694 |
| DOI | 10.1039/d3cc02056h |
| Web of Science KeyUT | 000999015900001 |
| Related Url | isVersionOf https://doi.org/10.1039/D3CC02056H |
| FullText URL | fulltext20230619-03.pdf fig1_20230619-03.pdf fig2_20230619-03.pdf fig3_20230619-03.pdf suppl20230619-03.pdf |
|---|---|
| Author | Akiyama, Mari| Akiyama, Tomoyuki| Saigusa, Daisuke| Hishinuma, Eiji| Matsukawa, Naomi| Shibata, Takashi| Tsuchiya, Hiroki| Mori, Atsushi| Fujii, Yuji| Mogami, Yukiko| Tokorodani, Chiho| Kuwahara, Kozue| Numata-Uematsu, Yurika| Inoue, Kenji| Kobayashi, Katsuhiro| |
| Keywords | Amino acids Biomarkers Intractable epilepsy Ketone bodies Organic acids |
| Note | © 2023 British Epilepsy Association. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at https://doi.org/10.1016/j.seizure.2023.03.014.| This fulltext file will be available in Apr. 2024.| |
| Published Date | 2023-04 |
| Publication Title | Seizure |
| Volume | volume107 |
| Publisher | Elsevier BV |
| Start Page | 52 |
| End Page | 59 |
| ISSN | 1059-1311 |
| NCID | AA1091615X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 British Epilepsy Association. |
| File Version | author |
| PubMed ID | 36958064 |
| DOI | 10.1016/j.seizure.2023.03.014 |
| Web of Science KeyUT | 000994635600001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.seizure.2023.03.014 |
| FullText URL | fulltext20230619-02.pdf |
|---|---|
| Author | Thu, Myat| Yanai, Kouta| Shigeto, Hajime| Yamamura, Shohei| Watanabe, Kazunori| Ohtsuki, Takashi| |
| Published Date | 2023 |
| Publication Title | Analyst |
| Volume | volume148 |
| Issue | issue11 |
| Publisher | Royal Society of Chemistry (RSC) |
| Start Page | 2626 |
| End Page | 2632 |
| ISSN | 0003-2654 |
| NCID | AA00524823 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Royal Society of Chemistry 2023 |
| File Version | publisher |
| PubMed ID | 37191032 |
| DOI | 10.1039/d3an00554b |
| Web of Science KeyUT | 000988019800001 |
| Related Url | isVersionOf https://doi.org/10.1039/D3AN00554B |
| FullText URL | fulltext20230619-01.pdf |
|---|---|
| Author | Matsumoto, Yoshinori| Rottapel, Robert| |
| Keywords | PARsylation ubiquitylation proteasomal degradation Cherubism tankyrase PARPs |
| Published Date | 2023-05 |
| Publication Title | Trends in Molecular Medicine |
| Volume | volume29 |
| Issue | issue5 |
| Publisher | Elsevier BV |
| Start Page | 390 |
| End Page | 405 |
| ISSN | 1471-4914 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 The Authors. |
| File Version | publisher |
| PubMed ID | 36948987 |
| DOI | 10.1016/j.molmed.2023.02.001 |
| Web of Science KeyUT | 000994672600001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.molmed.2023.02.001 |
| JaLCDOI | 10.18926/AMO/65504 |
|---|---|
| FullText URL | 77_3_335.pdf |
| Author | Fujii, Kentaro| Hirano, Shuichiro| Kurozumi, Kazuhiko| Date, Isao| |
| Abstract | An 85-year-old woman presented with aphasia due to an occupying lesion in the left frontal lobe near the language area. Complete resection of the contrast-enhancing lesion was performed under awake conditions. The pathological diagnosis was anaplastic astrocytoma, and postoperative radiochemotherapy was administered. Awake surgery is a useful technique to reduce postoperative neurological sequelae and to maximize surgical resection. Although the patient was elderly, which is generally considered high risk, she did not have any severe neurological deficits and had a good outcome. Even in the extreme elderly, awake surgery can be useful for gliomas in language cortices. |
| Keywords | awake surgery high-grade glioma eloquent area elderly patient |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 335 |
| End Page | 340 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357636 |
| Web of Science KeyUT | 001026663400002 |
| JaLCDOI | 10.18926/AMO/65503 |
|---|---|
| FullText URL | 77_3_331.pdf |
| Author | Watanabe, Mototsugu| Yamamoto, Hiromasa| Miyoshi, Kentaroh| Sugimoto, Seiichiro| Toyooka, Shinichi| |
| Abstract | Masaoka stage I type A thymomas rarely recur. We report the case of an 82-year-old man who developed endobronchial metastasis after thymothymectomy for Masaoka stage I type A thymoma. Twenty years after surgery, the patient developed bloody sputum, and chest computed tomography revealed a neoplasm obstructing the right upper lobe bronchus of the lung with enlarged mediastinal lymph nodes. He underwent right upper lobectomy and mediastinal lymph node dissection. Although preoperative pathological diagnosis was squamous cell carcinoma of the lung, postoperative histopathology revealed endobronchial metastasis of the thymoma. Nine years later, at age 89, the patient is alive and well. |
| Keywords | endobronchial metastasis type A thymoma bloody sputum |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 331 |
| End Page | 334 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357635 |
| Web of Science KeyUT | 001026663400001 |
| JaLCDOI | 10.18926/AMO/65502 |
|---|---|
| FullText URL | 77_3_323.pdf |
| Author | Makino, Keigo| Otani, Yoshihiro| Fujii, Kentaro| Ishida, Joji| Hirano, Shuichiro | Suruga, Yasuki| Washio, Kana| Nishida, Kenji| Yanai, Hiroyuki| Tomida, Shuta| Ennishi, Daisuke| Date, Isao| |
| Abstract | In the current World Health Organization classification of central nervous system tumors, comprehensive genetic and epigenetic analyses are considered essential for precise diagnosis. A 14-year-old male patient who presented with a cerebellar tumor was initially diagnosed with glioblastoma and treated with radiation and concomitant temozolomide chemotherapy after resection. During maintenance temozolomide therapy, a new contrast-enhanced lesion developed in the bottom of the cavity formed by the resection. A second surgery was performed, but the histological findings in specimens from the second surgery were different from those of the first surgery. Although genome-wide DNA methylation profiling was conducted using frozen tissue for a precise diagnosis, the proportion of tumor cells was insufficient and only normal cerebellum was observed. We then performed comprehensive genetic analysis using formalin-fixed paraffin-embedded sections, which revealed MYCN amplification without alteration of IDH1, IDH2, or Histone H3. Finally, the patient was diagnosed with pediatric-type diffuse high-grade glioma, H3-wildtype and IDH-wildtype. In conclusion, comprehensive genetic and epigenetic analysis should be considered in pediatric brain tumor cases. |
| Keywords | comprehensive genomic profiling pediatric brain tumor genome-wide DNA methylation MYCN |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 323 |
| End Page | 330 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357634 |
| Web of Science KeyUT | 001025850000001 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Shigeyasu, Yoshie| Okada, Ayumi| Fujii, Chikako| Tanaka, Chie| Sugihara, Akiko| Horiuchi, Makiko| Yorifuji, Takashi| Tsukahara, Hirokazu| |
| Keywords | Quality of life Orthostatic intolerance Psychosomatic factors School nonattendance Postural orthostatic tachycardia syndrome School-aged children Adolescence |
| Note | The version of record of this article, first published in BioPsychoSocial Medicine, is available online at Publisher’s website: http://dx.doi.org/10.1186/s13030-023-00278-1| |
| Published Date | 2023-06-12 |
| Publication Title | BioPsychoSocial Medicine |
| Volume | volume17 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 23 |
| ISSN | 1751-0759 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023. |
| File Version | publisher |
| PubMed ID | 37308984 |
| DOI | 10.1186/s13030-023-00278-1 |
| Web of Science KeyUT | 001003656700001 |
| Related Url | isVersionOf https://doi.org/10.1186/s13030-023-00278-1 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Goux, Pierre| Glessgen, Franz| Gazzola, Enrico| Reen, Mandeep Singh| Focillon, William| Gonin, Michel| Tanaka, Tomoyuki| Hagiwara, Kaito| Ali, Ajmi| Sudo, Takashi| Koshio, Yusuke| Sakuda, Makoto| Collazuol, Gianmaria| Kimura, Atsushi| Nakamura, Shoji| Iwamoto, Nobuyuki| Harada, Hideo| Wurm, Michael| |
| Published Date | 2023-05-05 |
| Publication Title | Progress of Theoretical and Experimental Physics |
| Volume | volume2023 |
| Issue | issue6 |
| Publisher | Oxford University Press |
| Start Page | 063H01 |
| ISSN | 2050-3911 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023. |
| File Version | publisher |
| DOI | 10.1093/ptep/ptad059 |
| Web of Science KeyUT | 000999497600002 |
| Related Url | isVersionOf https://doi.org/10.1093/ptep/ptad059 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Okada, Nobuhiro| Ueki, Chihiro| Shimazaki, Masahiro| Tsujimoto, Goki| Kohno, Susumu| Muranaka, Hayato| Yoshikawa, Kiyotsugu| Takahashi, Chiaki| |
| Note | The version of record of this article, first published in Communications Biology, is available online at Publisher’s website: http://dx.doi.org/10.1038/s42003-023-04987-9| |
| Published Date | 2023-06-02 |
| Publication Title | Communications Biology |
| Volume | volume6 |
| Issue | issue1 |
| Publisher | nature portfolio |
| Start Page | 596 |
| ISSN | 2399-3642 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| PubMed ID | 37268670 |
| DOI | 10.1038/s42003-023-04987-9 |
| Web of Science KeyUT | 000999915600001 |
| Related Url | isVersionOf https://doi.org/10.1038/s42003-023-04987-9 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Uchiyama, Takaki| Goto, Hidenori| Uesugi, Eri| Takai, Akihisa| Zhi, Lei| Miura, Akari| Hamao, Shino| Eguchi, Ritsuko| Ota, Hiromi| Sugimoto, Kunihisa| Fujiwara, Akihiko| Matsui, Fumihiko| Kimura, Koji| Hayashi, Kouichi| Ueno, Teppei| Kobayashi, Kaya| Akimitsu, Jun| Kubozono, Yoshihiro| |
| Note | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-023-27701-5| |
| Published Date | 2023-01-11 |
| Publication Title | Scientific Reports |
| Volume | volume13 |
| Issue | issue1 |
| Publisher | nature portfolio |
| Start Page | 537 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023 |
| File Version | publisher |
| PubMed ID | 36631625 |
| DOI | 10.1038/s41598-023-27701-5 |
| Web of Science KeyUT | 000986510100067 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-023-27701-5 |
| JaLCDOI | 10.18926/AMO/65497 |
|---|---|
| FullText URL | 77_3_319.pdf |
| Author | Kashihara, Kenichi| |
| Abstract | I report a case of arterial spine-labelled MR imaging (ASL)-detected cerebral hypoperfusion during migraine and panic attacks. A 20-year-old woman with a history of headache for 6 years and independent panic attacks for 3 years was transferred to Okayama Kyokuto Hospital for panic attacks. On that day, she had had severe headache that was improved by taking non-steroidal anti-inflammatory drug, but panic attacks initiated. On arrival, she also complained of a mild headache. ASL revealed cerebral hypoperfusion in the right temporo-occipital region. The threshold to induce panic attacks in migraine patients could be lowered by the physiopathology underlying migraine attacks. |
| Keywords | migraine panic attack arterial spine-labelled magnetic resonance imaging aura cortical spreading depression |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 319 |
| End Page | 321 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357633 |
| Web of Science KeyUT | 001026279600010 |
| JaLCDOI | 10.18926/AMO/65496 |
|---|---|
| FullText URL | 77_3_311.pdf |
| Author | Miura, Takanori| Kijima, Hiroaki| Tazawa, Hiroshi| Miyakoshi, Naohisa| |
| Abstract | Japan’s hip fracture management guidelines now recommend the use of cemented stems in cases of bone fragility. However, the current stem selection practices in bipolar hemiarthroplasty (BHA) in a super-aging area in Japan remain unclear. This study aimed to examine the stem selection policies, the surgeons’ concerns about cemented stems, and factors affecting their confidence in their ability to coach others on cemented stem procedures. Ninety-four orthopedic surgeons (27 facilities) responded to our web-based questionnaire conducted in January/February 2022. Cementless stem was the first choice of 97.8% of the surgeons; <15% of the respondents expected to increase their use of cemented stems in the future. The cement technique was the greatest concern; almost half of the surgeons described having insufficient experience with cemented stems. The factor that most affected the surgeons’ expertise in using cemented stems is the number of surgeries they had conducted with a cemented stem (multivariable analysis odds ratio 8.42, p=0.001). Greater experience was associated with increased expertise of the surgeons in using cemented stems, with a threshold of 11 cases showing sensitivity of 41.7% and specificity of 98.3% for their confidence to instruct cemented stems. |
| Keywords | hip fracture arthroplasty bone cement questionnaire |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 311 |
| End Page | 318 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357632 |
| Web of Science KeyUT | 001026279600009 |
| JaLCDOI | 10.18926/AMO/65495 |
|---|---|
| FullText URL | 77_3_301.pdf |
| Author | Kato, Takahide| Miyoshi, Seigo| Hamada, Chizuru| Sano, Yoshifumi| Nogami, Naoyuki| Yamaguchi, Osamu| Hamaguchi, Naohiko| |
| Abstract | Acute exacerbation (AE) of interstitial lung disease (ILD) is a severe complication of lung resection in lung cancer patients with ILD (LC-ILD). This study aimed to assess the predictive value of comorbidities other than ILD for postoperative AE in patients with LC-ILD. We retrospectively evaluated 68 patients with LC-ILD who had undergone lung resection. We classified them into two groups: those who had developed postoperative AE within 30 days after resection and those who had not. We analyzed patient characteristics, high-resolution computed tomography findings, clinical data, pulmonary function, and intraoperative data. The incidence of postoperative AEs was 11.8%. In univariate analysis, performance status (PS), honeycombing, forced vital capacity (FVC), and high hemoglobin A1c (HbA1c) levels without comorbidities were significantly associated with postoperative AE. Patients were divided into two groups according to cutoff levels of those four variables as determined by receiver operating characteristic curves, revealing that the rates of patients without postoperative AE differed significantly between groups. The present results suggested that preoperative comorbidities other than ILD were not risk factors for postoperative AE in patients with LC-ILD. However, a high preoperative HbA1c level, poor PS, low FVC, and honeycombing may be associated with postoperative AE of LC-ILD. |
| Keywords | lung cancer interstitial lung disease acute exacerbation comorbidity |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 301 |
| End Page | 309 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357631 |
| Web of Science KeyUT | 001026279600008 |
| JaLCDOI | 10.18926/AMO/65494 |
|---|---|
| FullText URL | 77_3_291.pdf |
| Author | Himei, Hitomi| Kato, Hironari| Saragai, Yosuke| Fujii, Yuki| Yamazaki, Tatsuhiro| Uchida, Daisuke| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Tsutsumi, Koichiro| Okada, Hiroyuki| |
| Abstract | We investigated the efficacy and safety of endoscopic plastic stent (PS) placement for hilar benign biliary strictures (BBSs) and compared cases with PS placement above (inside stent, IS) and across (usual stent, US) the sphincter of Oddi. Patients who underwent initial endoscopic PS placement for hilar BBSs between August 2012 and December 2021 were retrospectively analyzed. Hilar BBSs in 88 patients were investigated. Clinical success was achieved in 81 of these cases (92.0%), including 38 patients in the IS group and 43 patients in the US group. Unexpected stent exchange (uSE) before the first scheduled PS exchange occurred in 18 cases (22.2%). The median time from first stent placement to uSE was 35 days. There was no significant difference in the rate and median time to uSE between the two groups. The rates of adverse events such as pancreatitis or cholangitis in the two groups did not significantly differ. However, the rate of difficult stent removal in the IS group (15.8%) was significantly higher than that in the US group (0%) (p=0.0019). US placement is preferable to IS placement for scheduled stent exchange, as it offers the same effectiveness and risk of adverse events with easier stent removal. |
| Keywords | benign biliary stricture inside stent plastic stent |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 291 |
| End Page | 299 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357630 |
| Web of Science KeyUT | 001026279600007 |
| JaLCDOI | 10.18926/AMO/65493 |
|---|---|
| FullText URL | 77_3_281.pdf |
| Author | Mukai, Yuko| Taira, Naruto| Kajiwara, Yukiko| Iwamoto, Takayuki| Kitaguchi, Yohei| Saiga, Miho| Watanabe, Satoko| Shien, Tadahiko| Doihara, Hiroyoshi| Kimata, Yoshihiro| |
| Abstract | Although immediate breast reconstruction following mastectomy has become increasingly common, its oncological safety has been debated. We enrolled patients with breast cancer who underwent surgery at Okayama University Hospital between 2007 and 2013. The primary outcome was relapse-free survival (RFS). Secondary outcomes were overall survival and the duration from the surgery to the initiation of adjuvant chemotherapy. We divided into immediate breast reconstruction, mastectomy alone, and breast conservative surgery groups. Outcomes were compared using Cox’s regression analysis. A total of 614 patients were included (reconstruction: 125, mastectomy: 128, breast conservative surgery: 361). The median follow-up duration was 79.0±31.9 months. The immediate-reconstruction patients were younger, had more lymph node metastases, and more often received postoperative chemotherapy. The RFS was better after the breast conservative surgery compared to after reconstruction (hazard ratio 0.33, 95% confidence interval: 0.144-0.763). The proportion of local recurrence was highest in the reconstruction group. No patients in the reconstruction group underwent postoperative radiation therapy. However, reconstruction did not affect overall survival or the time to the initiation of adjuvant chemotherapy. Surgeons should explain the risks of breast reconstruction to their patients preoperatively. Careful long-term follow-up is required after such procedures. |
| Keywords | immediate breast reconstruction oncological safety local recurrence postoperative radiation therapy time to initiation of adjuvant chemotherapy |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 281 |
| End Page | 290 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357629 |
| Web of Science KeyUT | 001026279600006 |
| JaLCDOI | 10.18926/AMO/65492 |
|---|---|
| FullText URL | 77_3_273.pdf |
| Author | Shimizu, Yudai| Kuroda, Masahiro| Nakamitsu, Yuki| Al-Hammad, Wlla E.| Yoshida, Suzuka| Fukumura, Yuka| Nakamura, Yoshihide| Kuroda, Kazuhiro| Kamizaki, Ryo| Imajoh, Satoshi| Tanabe, Yoshinori| Sugimoto, Kohei| Oita, Masataka| Sugianto, Irfan| Bamgbose, Babatunde O.| Yanagi, Yoshinobu| Asaumi, Junichi| |
| Abstract | Diffusion kurtosis (DK) imaging (DKI), a type of restricted diffusion-weighted imaging, has been reported to be useful for tumor diagnoses in clinical studies. We developed a software program to simultaneously create DK images with apparent diffusion coefficient (ADC) maps and conducted an initial clinical study. Multi-shot echo-planar diffusion-weighted images were obtained at b-values of 0, 400, and 800 sec/mm2 for simple DKI, and DK images were created simultaneously with the ADC map. The usefulness of the DK image and ADC map was evaluated using a pixel analysis of all pixels and a median analysis of the pixels of each case. Tumor and normal tissues differed significantly in both pixel and median analyses. In the pixel analysis, the area under the curve was 0.64 for the mean kurtosis (MK) value and 0.77 for the ADC value. In the median analysis, the MK value was 0.74, and the ADC value was 0.75. The MK and ADC values correlated moderately in the pixel analysis and strongly in the median analysis. Our simple DKI system created DK images simultaneously with ADC maps, and the obtained MK and ADC values were useful for differentiating head and neck tumors from normal tissue. |
| Keywords | simple diffusion kurtosis imaging mean kurtosis clinical trial head and neck tumor magnetic resonance imaging |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 273 |
| End Page | 280 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357628 |
| Web of Science KeyUT | 001026279600005 |
| JaLCDOI | 10.18926/AMO/65491 |
|---|---|
| FullText URL | 77_3_263.pdf |
| Author | Guo, Yusheng| Kosaka, Junko| Morimatsu, Hiroshi| |
| Abstract | Continuous renal replacement therapy (CRRT) is widely used to control fluid balance, but the optimal fluid balance to improve the prognosis of patients remains debated. Appropriate fluid management may depend on hemodynamic status. We investigated the association between 90-day mortality and fluid balance/mean arterial pressure (MAP) in patients receiving CRRT. This single-center retrospective study was conducted between May 2018 and March 2021. Based on the cumulative fluid balance at 72 h after initiation of CRRT, the cases were divided into negative (< 0 mL) and positive (> 0 mL) fluid balance groups. Ninety-day mortality was higher in the positive fluid balance group (p=0.009). At 4 h before and after CRRT initiation, the mean MAP was lower in the positive fluid balance group (p<0.05). After multivariate cox adjustment, 72-h positive fluid balance was independently associated with 90-day mortality (p=0.004). In addition, the cumulative fluid balance was associated with 90-day mortality (p<0.05) in cases without shock, high APACHE II score, sepsis, dialysis dependence, or vasopressor use. A 72-h positive fluid balance was associated with 90-day mortality in patients receiving CRRT. |
| Keywords | fluid management continuous renal replacement therapy mortality mean arterial pressure daily cumulative fluid balance |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 263 |
| End Page | 272 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357627 |
| Web of Science KeyUT | 001026279600004 |
