検索結果 - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Clinical Application of the Ratio of Serum Bone Isoform to Total Alkaline Phosphatase in General Practice

JaLCDOI	10.18926/AMO/61205
FullText URL	74_6_467.pdf
Author	Yokota, Yuya\| Nishimura, Yoshito\| Ando, Akemi\| Hanayama, Yoshihisa\| Hasegawa, Kou\| Hagiya, Hideharu\| Ogawa, Hiroko\| Obika, Mikako\| Ueda, Keigo\| Otsuka, Fumio\|
Abstract	Alkaline phosphatase (ALP) is an enzyme that is expressed in a variety of tissues. Among the isoforms of ALP, bone-specific alkaline phosphatase (BAP) is used as a marker for evaluating bone metabolism. We investigated the clinical usefulness of the ratio of serum BAP to total ALP for the diagnosis of various disorders in general practice. We retrospectively analyzed the cases of 107 Japanese patients whose serum BAP levels were exam-ined, focusing on clinical characteristics. We observed that the BAP/ALP ratios of the patients with fever and those with inflammatory diseases were significantly lower than the ratios of other patient groups. The BAP/ALP ratios of the patients with osteoporosis and those with metabolic bone diseases were higher than those of the patients with other conditions. The BAP/ALP ratio was found to be negatively correlated with age, a cor-relation that has not been found in other ethnicities. The serum BAP/ALP ratio was inversely correlated with serum CRP levels but was positively correlated with serum albumin levels and hemoglobin concentrations. Collectively, our results suggest that the BAP/ALP ratio could be a useful predictor for important geriatric con-ditions seen in general practice.
Keywords	alkaline phosphatase BAP CRP inflammation osteoporosis
Amo Type	Original Article
Publication Title	Acta Medica Okayama
Published Date	2020-12
Volume	volume74
Issue	issue6
Publisher	Okayama University Medical School
Start Page	467
End Page	474
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2020 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	33361866
Web of Science KeyUT	000601203600002
NAID	120006948955

Detection of epidermal growth factor receptor mutations in exhaled breath condensate using droplet digital polymerase chain reaction

FullText URL	fulltext.pdf
Author	Nishii, Kazuya\| Ohashi, Kadoaki\| Tamura, Tomoki\| Ninomiya, Kiichiro\| Matsubara, Takehiro\| Senoo, Satoru\| Kano, Hirohisa\| Watanabe, Hiromi\| Oda, Naohiro\| Makimoto, Go\| Higo, Hisao\| Kato, Yuka\| Ninomiya, Takashi\| Kubo, Toshio\| Yamamoto, Hiromasa \| Tomida, Shuta\| Hotta, Katsuyuki\| Tabata, Masahiro\| Toyooka, Shinichi\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Keywords	non-small cell lung cancer epidermal growth factor receptor mutations droplet digital PCR exhaled breath condensate EGFR-TKIs
Published Date	2020-12
Publication Title	Oncology Letters
Volume	volume20
Issue	issue6
Publisher	Spandidos Publications
Start Page	393
ISSN	1792-1074
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	publisher
PubMed ID	33193853
DOI	10.3892/ol.2020.12256
Web of Science KeyUT	000595649300005
Related Url	isVersionOf https://doi.org/10.3892/ol.2020.12256

Life-Course Monitoring of Endogenous Phytohormone Levels under Field Conditions Reveals Diversity of Physiological States among Barley Accessions

FullText URL	fulltext.pdf
Author	Hirayama, Takashi\| Saisho, Daisuke\| Matsuura, Takakazu\| Okada, Satoshi\| Takahagi, Kotaro\| Kanatani, Asaka\| Ito, Jun\| Tsuji, Hiroyuki\| Ikeda, Yoko\| Mochida, Keiichi\|
Keywords	transcriptome barley filed conditions hormone profiling life-course monitoring
Published Date	2020-04-15
Publication Title	Plant and Cell Physiology
Volume	volume61
Issue	issue8
Publisher	Oxford University Press
Start Page	1438
End Page	1448
ISSN	0032-0781
NCID	AA0077511X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	32294217
DOI	10.1093/pcp/pcaa046
Web of Science KeyUT	000593148100008
Related Url	isVersionOf https://doi.org/10.1093/pcp/pcaa046

Geometrical Structure of Honeycomb TCP to Control Dental Pulp-Derived Cell Differentiation

FullText URL	fulltext.pdf
Author	Takabatake, Kiyofumi\| Tsujigiwa, Hidetsugu\| Nakano, Keisuke\| Inada, Yasunori\| Qiusheng, Shan\| Kawai, Hotaka\| Sukegawa, Shintaro \| Fushimi, Shigeko\| Nagatsuka, Hitoshi\|
Keywords	dental pulp honeycomb TCP matrix formation dentin formation geometrical structure scaffold
Published Date	2020-11-16
Publication Title	Materials
Volume	volume13
Issue	issue22
Publisher	MDPI
Start Page	5155
ISSN	1996-1944
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by the authors.
File Version	publisher
PubMed ID	33207665
DOI	10.3390/ma13225155
Web of Science KeyUT	000594220200001
Related Url	isVersionOf https://doi.org/10.3390/ma13225155

Micro-Architectural Investigation of Teleost Fish Rib Inducing Pliant Mechanical Property

FullText URL	fulltext.pdf
Author	Jiao, Yu Yang\| Okada, Masahiro\| Hara, Emilio Satoshi\| Xie, Shi Chao\| Nagaoka, Noriyuki\| Nakano, Takayoshi\| Matsumoto, Takuya\|
Keywords	bone-like material mechanical property orientation layered structure
Published Date	2020-11-12
Publication Title	Materials
Volume	volume13
Issue	issue22
Publisher	MDPI
Start Page	5099
ISSN	1996-1944
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by the authors.
File Version	publisher
PubMed ID	33198178
DOI	10.3390/ma13225099
Web of Science KeyUT	000594906000001
Related Url	isVersionOf https://doi.org/10.3390/ma13225099

Mineralogical alterations in calcite powder flooded with MgCl2 to study Enhanced Oil Recovery (EOR) mechanisms at pore scale

FullText URL	fulltext.pdf
Author	Minde, Mona W.\| Madland, Merete V.\| Zimmermann, Udo\| Egeland, Nina\| Korsnes, Reidar I.\| Nakamura, Eizo\| Kobayashi, Katsura\| Ota, Tsutomu\|
Keywords	Mineral replacement reactions EOR Calcite FE-SEM FE-TEM
Published Date	2020-09
Publication Title	Microporous and Mesoporous Materials
Volume	volume304
Publisher	Elsevier
Start Page	109402
ISSN	1387-1811
NCID	AA11160707
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2019 The Authors.
File Version	publisher
DOI	10.1016/j.micromeso.2019.03.050
Web of Science KeyUT	000546913300015
Related Url	isVersionOf https://doi.org/10.1016/j.micromeso.2019.03.050

Degradation of Mutant Protein Aggregates within the Endoplasmic Reticulum of Vasopressin Neurons

FullText URL	fulltext.pdf
Author	Miyata, Takashi\| Hagiwara, Daisuke\| Hodai, Yuichi\| Miwata, Tsutomu\| Kawaguchi, Yohei\| Kurimoto, Junki\| Ozaki, Hajime\| Mitsumoto, Kazuki\| Takagi, Hiroshi\| Suga, Hidetaka\| Kobayashi, Tomoko\| Sugiyama, Mariko\| Onoue, Takeshi\| Ito, Yoshihiro\| Iwama, Shintaro\| Banno, Ryoichi\| Matsumoto, Mami\| Kawakami, Natsuko\| Ohno, Nobuhiko\| Sakamoto, Hirotaka\| Arima, Hiroshi\|
Published Date	2020-10-23
Publication Title	iScience
Volume	volume23
Issue	issue10
Publisher	Cell Press
Start Page	101648
ISSN	2589-0042
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Authors.
File Version	publisher
PubMed ID	33103081
DOI	10.1016/j.isci.2020.101648
Web of Science KeyUT	000581985500098
Related Url	isVersionOf https://doi.org/10.1016/j.isci.2020.101648

Oxytocin Influences Male Sexual Activity via Non-synaptic Axonal Release in the Spinal Cord

FullText URL	fulltext.pdf
Author	Oti, Takumi\| Satoh, Keita\| Uta, Daisuke\| Nagafuchi, Junta\| Tateishi, Sayaka\| Ueda, Ryota\| Takanami, Keiko\| Young, Larry J.\| Galione, Antony\| Morris, John F.\| Sakamoto, Tatsuya\| Sakamoto, Hirotaka\|
Keywords	oxytocin localized volume transmission spinal cord male sexual activity gastrin-releasing peptide spinal ejaculation generator
Note	© 2020 Elsevier. This manuscript version is made available under the CC-BY-NC-ND 4.0 License.http://creativecommons.org/licenses/by-nc-nd/4.0/.This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.cub.2020.09.089] .\|
Published Date	2020-10-29
Publication Title	Current Biology
Volume	volume31
Issue	issue1
Publisher	Elsevier
Start Page	103
End Page	114.e5
ISSN	0960-9822
NCID	AA1081652X
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
PubMed ID	33125871
DOI	10.1016/j.cub.2020.09.089
Related Url	isVersionOf https://doi.org/10.1016/j.cub.2020.09.089

Concomitant vancomycin and piperacillin/tazobactam treatment is associated with an increased risk of acute kidney injury in Japanese patients

FullText URL	JIC_26.pdf
Author	Haruki, Yuto\| Hagiya, Hideharu\| Haruki, Mai\| Inoue, Yuta\| Sugiyama, Tetsuhiro\|
Keywords	Acute kidney injury β-lactams Piperacillin/tazobactam Vancomycin
Note	This fulltext is available in Oct. 2021.\|
Published Date	2020-10
Publication Title	Journal of Infection and Chemotherapy
Volume	volume26
Issue	issue10
Publisher	Elsevier
Start Page	1026
End Page	1032
ISSN	1341-321X
NCID	AA11057978
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	32561128
DOI	10.1016/j.jiac.2020.05.012
Web of Science KeyUT	000561076200003
Related Url	isVersionOf https://doi.org/10.1016/j.jiac.2020.05.012

Cadmium transfer in contaminated soil-rice systems: Insights from solid-state speciation analysis and stable isotope fractionation

FullText URL	fulltext.pdf
Author	Wiggenhauser, Matthias\| Aucour, Anne-Marie\| Bureau, Sarah\| Campillo, Sylvain\| Telouk, Philippe\| Romani, Marco\| Ma, Jian Feng\| Landrot, Gautier\| Sarret, Géraldine\|
Keywords	Cadmium Rice Isotopes Speciation Membrane transporter Vacuole Sulfur Redox
Published Date	2020-11-09
Publication Title	Environmental Pollution
Volume	volume269
Publisher	Elsevier
Start Page	115934
ISSN	0269-7491
NCID	AA10664567
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Author(s).
File Version	publisher
DOI	10.1016/j.envpol.2020.115934
Related Url	isVersionOf https://doi.org/10.1016/j.envpol.2020.115934

Self-assembling A6K peptide nanotubes as a mercaptoundecahydrododecaborate (BSH) delivery system for boron neutron capture t (BNCT)

FullText URL	fulltext.pdf
Author	Michiue, Hiroyuki\| Kitamatsu, Mizuki\| Fukunaga, Asami\| Tsuboi, Nobushige\| Fujimura, Atsushi\| Matsushita, Hiroaki\| Igawa, Kazuyo\| Kasai, Tomonari\| Kondo, Natsuko\| Matsui, Hideki\| Furuya, Shuichi\|
Keywords	Malignant brain tumor Boron neutron capture therapy (BNCT) Peptide nanotube Boron drug Drug delivery system (DDS) A6K peptide
Published Date	2020-11-11
Publication Title	Journal of Controlled Release
Volume	volume330
Publisher	Elsevier
Start Page	788
End Page	196
ISSN	0168-3659
NCID	AA10458678
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Author(s).
File Version	publisher
PubMed ID	33188824
DOI	10.1016/j.jconrel.2020.11.001
Related Url	isVersionOf https://doi.org/10.1016/j.jconrel.2020.11.001

Roles of CCN2 as a mechano-sensing regulator of chondrocyte differentiation

FullText URL	fulltext.pdf
Author	Nishida, Takashi\| Kubota, Satoshi\|
Keywords	Mechanoreceptors Cellular communication network factor 2 (CCN2) Mechanical stress Chondrocytes
Published Date	2020-11
Publication Title	Japanese Dental Science Review
Volume	volume56
Issue	issue1
Publisher	Elsevier
Start Page	119
End Page	126
ISSN	1882-7616
NCID	AA12334461
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	publisher
PubMed ID	33088364
DOI	10.1016/j.jdsr.2020.07.001
Web of Science KeyUT	000598681800016
Related Url	isVersionOf https://doi.org/10.1016/j.jdsr.2020.07.001

Patient-reported outcomes with first-line durvalumab plus platinum-etoposide versus platinum-etoposide in extensive-stage small-cell lung cancer (CASPIAN): a randomized, controlled, open-label, phase III study

FullText URL	fulltext.pdf
Author	Goldman, Jonathan W.\| Garassino, Marina Chiara\| Chen, Yuanbin\| Özgüroğlu, Mustafa\| Dvorkin, Mikhail\| Trukhin, Dmytro\| Statsenko, Galina\| Hotta, Katsuyuki\| Ji, Jun Ho\| Hochmair, Maximilian J.\| Voitko, Oleksandr\| Havel, Libor\| Poltoratskiy, Artem\| Losonczy, György\| Reinmuth, Niels\| Patel, Nikunj\| Laud, Peter J.\| Shire, Norah\| Jiang, Haiyi\| Paz-Ares, Luis\|
Keywords	Small-cell lung cancer Durvalumab Platinum-etoposide CASPIAN Patient-reported outcomes Health-related quality of life
Published Date	2020-11
Publication Title	Lung Cancer
Volume	volume149
Publisher	Elsevier
Start Page	46
End Page	52
ISSN	0169-5002
NCID	AA10785743
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Authors.
File Version	publisher
PubMed ID	32961445
DOI	10.1016/j.lungcan.2020.09.003
Web of Science KeyUT	000579504300008
Related Url	isVersionOf https://doi.org/10.1016/j.lungcan.2020.09.003

Cryphonectria nitschkei chrysovirus 1 with unique molecular features and a very narrow host range

FullText URL	fulltext.pdf
Author	Shahi, Sabitree\| Chiba, Sotaro\| Kondo, Hideki\| Suzuki, Nobuhiro\|
Keywords	Cryphonectria nitschkei Cryphonectria parasitica Cryphonectria radicalis Chrysovirus Fungal virus dsRNA Host range
Published Date	2021-02
Publication Title	Virology
Volume	volume554
Publisher	Elsevier
Start Page	55
End Page	62
ISSN	0042-6822
NCID	AA00884454
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	33383414
DOI	10.1016/j.virol.2020.11.011
Web of Science KeyUT	000608838900008
Related Url	isVersionOf https://doi.org/10.1016/j.virol.2020.11.011

Self-assembly of Ni–Fe layered double hydroxide at room temperature for oxygen evolution reaction

FullText URL	fulltext.pdf
Author	Kim, Seong Hyun\| Park, Yoo Sei\| Kim, Chiho\| Kwon, Il Yeong\| Lee, Jooyoung\| Jin, Hyunsoo\| Lee, Yoon-Seok\| Choi, Sung Mook\| Kim, Yangdo\|
Keywords	Water electrolysis Oxygen evolution reaction NiFe layered double hydroxide Room temperature synthesis Electrocatalyst
Published Date	2020-12-04
Publication Title	Energy Reports
Volume	volume6
Issue	issueSuppl. 7
Publisher	Elsevier
Start Page	248
End Page	254
ISSN	2352-4847
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Authors.
File Version	publisher
DOI	10.1016/j.egyr.2020.10.007
Web of Science KeyUT	000604361900022
Related Url	isVersionOf https://doi.org/10.1016/j.egyr.2020.10.007

Randomized phase II study to determine the optimal dose of 3-week cycle nab-paclitaxel in patients with metastatic breast cancer

FullText URL	fulltext.pdf
Author	Tsurutani, Junji\| Hara, Fumikata\| Kitada, Masahiro\| Takahashi, Masato\| Kikawa, Yuichiro\| Kato, Hiroaki\| Sakata, Eiko\| Naito, Yoichi\| Hasegawa, Yoshie\| Saito, Tsuyoshi\| Iwasa, Tsutomu\| Taira, Naruto\| Takashima, Tsutomu\| Kashiwabara, Kosuke\| Aihara, Tomohiko\| Mukai, Hirofumi\|
Keywords	Nab-paclitaxel Nanoparticle albumin–bound paclitaxel Metastatic breast cancer Solvent-base paclitaxel Chemotherapy-induced peripheral neuropathy
Published Date	2020-12-09
Publication Title	The Breast
Volume	volume55
Publisher	Elsevier
Start Page	63
End Page	68
ISSN	0960-9776
NCID	AA10844161
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Authors.
File Version	publisher
DOI	10.1016/j.breast.2020.12.002
Related Url	isVersionOf https://doi.org/10.1016/j.breast.2020.12.002

Construction and characterization of the PGN_0296 mutant of Porphyromonas gingivalis

FullText URL	fulltext.pdf
Author	Shahriar, Abu Saleh Muhammad\| Ono, Shintaro\| Nakayama, Masaaki\| Ohara, Naoko\| Ohara, Naoya\|
Keywords	Porphyromonas gingivalis Periodontal diseases Gingipain Bacterial secretion system
Note	© 2020 Japanese Association for Oral Biology. This manuscript version is made available under the CC-BY-NC-ND 4.0 License.http://creativecommons.org/licenses/by-nc-nd/4.0/.This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.job.2020.09.007] .\|
Published Date	2020-12
Publication Title	Journal of Oral Biosciences
Volume	volume62
Issue	issue4
Publisher	Elsevier
Start Page	322
End Page	326
ISSN	1349-0079
NCID	AA11896386
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 Japanese Association for Oral Biology.
File Version	author
PubMed ID	33038516
DOI	10.1016/j.job.2020.09.007
Web of Science KeyUT	000597154900005
Related Url	isVersionOf https://doi.org/10.1016/j.job.2020.09.007

A case of rhinocerebral mucormycosis with brain abscess drained by endoscopic endonasal skull base surgery

FullText URL	fulltext.pdf
Author	Uraguchi, Kensuke\| Kozakura, Kenichi\| Oka, Satoshi\| Higaki, Takaya\| Makihara, Seiichiro\| Imai, Toshi\| Doi, Akira\| Ohta, Tsuyoshi\| Kariya, Shin\| Nishizaki, Kazunori\|
Keywords	Rhinocerebral mucormycosis Acute rhinosinusitis Brain abscess Endoscopic endonasal skull base surgery Acute monocytic leukemia
Published Date	2020-12
Publication Title	Medical Mycology Case Reports
Volume	volume30
Publisher	Elsevier
Start Page	22
End Page	25
ISSN	2211-7539
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Authors.
File Version	publisher
PubMed ID	33083212
DOI	10.1016/j.mmcr.2020.09.004
Web of Science KeyUT	000600608700007
Related Url	isVersionOf https://doi.org/10.1016/j.mmcr.2020.09.004

Extracorporeal membrane oxygenation in Stenotrophomonas maltophilia pneumonia during acute myeloid leukemia: A case report

FullText URL	fulltext.pdf
Author	Saito, Kenki\| Aokage, Toshiyuki\| Sato, Takayuki\| Tsukahara, Kohei\| Tokioka, Fumiaki\| Otake, Takanao\| Irie, Hiromasa\| Ueda, Yasunori\|
Keywords	Stenotrophomonas maltophilia Severe pneumonia Acute panmyelosis with myelofibrosis Acute myeloid leukemia Extracorporeal membrane oxygenation
Published Date	2020-12
Publication Title	Respiratory Medicine Case Reports
Volume	volume31
Publisher	Elsevier
Start Page	101224
ISSN	2213-0071
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Author(s).
File Version	publisher
PubMed ID	32995263
DOI	10.1016/j.rmcr.2020.101224
Web of Science KeyUT	000600668000086
Related Url	isVersionOf https://doi.org/10.1016/j.rmcr.2020.101224

Technique for single-step lymphocyte isolation from an endoscopic biopsy specimen for the diagnosis of gastrointestinal lymphoma

FullText URL	fulltext.pdf
Author	Iwamuro, Masaya\| Takahashi, Takahide\| Watanabe, Natsuki\| Omote, Sizuma\| Matsueda, Katsunori\| Tanaka, Takehiro\| Ennishi, Daisuke\| Otsuka, Fumio\| Yoshino, Tadashi\| Okada, Hiroyuki\|
Keywords	Flow cytometry Light chain restriction Gastrointestinal lymphoma Lymphocyte isolation
Published Date	2020
Publication Title	MethodsX
Volume	volume7
Publisher	Elsevier
Start Page	101095
ISSN	2215-0161
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Author(s).
File Version	publisher
PubMed ID	33102158
DOI	10.1016/j.mex.2020.101095
Web of Science KeyUT	000607658800035
Related Url	isVersionOf https://doi.org/10.1016/j.mex.2020.101095

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