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JaLCDOI 10.18926/40347
Title Alternative KLINISCHE UND EXPERIMENTELLE UNTERSUCHUNGEN ÜBER DIE WIRKUNG VON THERMALBÄDERN AUF DIE SEXUALFUNKTION VON FRAUEN (5) UNTERSUCHUNGEN ÜBER DIE BEEINFLUSSUNG DER QUAINTITÄT DER ACETYLCHOLINARTIGEN SUBSTANZ IN ZWISCHENHIRN DER RATTE NACH THERMALBADE
FullText URL pitsr_013_031_035.pdf
Author Tanaka, Yosinori|
Abstract In frühen Arbeiten habe ich den Nachweiss erbracht, dass Thermalbädern den Brunstzyklus der weiblichen Ratten regelmässig werden lassen, und diese Erscheinung auf die Steigerung der Hupophysenvorderlappenfunktion zurückzuführen ist. Andererseits ist es bekannt, dass Zunahme der acetylcholinartigen Substanz der Zwischenhirn die Steigerung der Hypophysenvorderlappenfunktion mit sich bringt. Unter diesen Gesichtspunkten wurden die Bestimmnngen der acetylcholinartigen Substanz in zwischenhirn der Ratte nach Thermalbade vorgennommen. 47 männliche Ratte wurden in Misasa Therma - radioaktive Thermen - 10 Minuten lang bei 42°C gebadet, dann in 4 Gruppen geteilt, und εfort, an 30., 60., und 90. Minute nach dem Bade wurde diese Subfotanz nach Methode von M. rectus abdeminis der Frosch bestimmt, und mit kontrolltiere verglichen. Es wurde festgestellt, dass freie acetylcholinartige Snbstanz sich an 30. Minute nach dem Bade vermehrte, aber an anderen Zeiten kein statistisch signifikanter Unterschied zwischen Badgruppe lmd Kontrollgruppre hinisichtlich des Gehalt der freien, kombinierten und gesamten acetylcholinartigen Subtanz war. Die Tatsachen lassen daran denken, dass Zunahme der freien acetylcholinartigen Substanz in Zwischenhirn, die gescbah nach dem Thermalbade, sich an Verbesserung der Sexualfunktion von Thermalbädern vielleicht beteiligt. Üher diese Erscheinungen werden die Rolle der Radiumemanation im Thermalwasser und Unterschied zwischen Thermalwasser und Süsswasser in künftigen Arbeiten untersucht werden.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 31
End Page 35
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40340
language Japanese
File Version publisher
NAID 120002484881
JaLCDOI 10.18926/40346
Title Alternative STUDIES ON SERUM MUCOPROTEIN (2) RELATION BETWEEN SERUM MUCOPROTEIN LEVEL AND DIFFERENTIAL AGGLUTINATION TEST FOR RHEUMATOID ARTHRITIS. AN EXPERIMENTAL AND CLINICAL STUDY
FullText URL 013_024_030.pdf
Author Ueda, Yoshio|
Abstract (1) Mucoprotein level in serum and agglutination reaction by Rose for rheumatoid arthritis were measured in 40 cases of rheumatoid arthritis, cancer, pulmonary tuberculosis or liver disease (mostly acute hepatitis). A raised titer of mucoprotein was often observed in cancer, and a marked rise in agglutination titer was often proved in rheumatoid arthritis. But no significant correlation was proved between the serum mucoprotein level and agglutination test in patients. (2) [n animal experiment an inereased agglutination titer was caused by sensitization with egg albumin, Arthus' s phenomenon, anaphylactic, shock, thermal spring bath, X-ray irradiation, blocking of reticuloendothelial system, liver injuries, injection of A. C. T. H., adrenaline, atropin or pilocarpin. A simultaneoas rise in serum mucoprotein level was observed after sensitization, thermal bath, X-ray irradiation, administmtion of chloroform, injection of toxic agents to vegetative nerve system. And a significant positive linear correlation was proved between the serum mucoprotein level and agglutination titer in the animal experiment on the whole. But a dissociation in this relation was observed during anaphylactic shok. Namely serum mucoprotein level tended to fall soon after the reinjection, while the agglutination titer rose higher temporarily and then both showed a tendency to decrease.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 24
End Page 30
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40340
language Japanese
File Version publisher
NAID 40017532450
JaLCDOI 10.18926/40345
Title Alternative BALNEOLOGICAL STUDIES USING RADIOACTIVE ISOTOPES (3)
FullText URL pitsr_013_018_023.pdf
Author Yokota, Takeo| Ashizawa, Takashi|
Abstract By using labelled sodium sulfate or calcium sulfate (sulfate containing S(35)) the transition of sulfate ion into the body across the skin was investigated soon after taking a bath in sodium sulfate or calcium sulfate solution under varing conditions. Mice were used for experiments. The percutaneous absorption of sulfate ion proved to decrease gradually in the course of serial baths in sodium sulfate solntion and was accelerated by making a fresh burn on the skin of the bathed animals, but it showed a tendency to decrease as the wound became more and more healed. The application of basic dye to the skin (e.g. 1% methylenblue or 1% fuchsin solution) increased the transition of sulfate ion into the test animal. Little difference was proved between the bath in sodium sulfate and calcium sulfate solution with respect to the penetration of sulfate ion. Passage of sulfate ion from the bath water through the skin was a little promoted by the use of sodium sulfate solution than by the use of calcium sulfate solution.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 18
End Page 23
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40340
language Japanese
File Version publisher
NAID 120002484880
JaLCDOI 10.18926/40344
Title Alternative STUDIES ON VITRIOL SPRINGS (4) ON THE COPPER, ZINC, NICKEL, AND COBALT CONTENTS OF BLOOD AFTER THE INTERNAL USE OF A VITRIOL WATER
FullText URL 013_015_017.pdf
Author Oshima, Yoshio| Ashizawa, Takashi|
Abstract Sotozono proved that the administration of daily 20cc of Fujino Mineral Water (an acid vitriol water containing copper, zinc, nickel and cobalt) has a remarkably beneficial effect on several kinds of hypochromic anemia. It contains 9.56gms of iron, 0.007gm of zinc, 0.005gm of copper 0.001gm of nickel, and 0.006gm of cobalt in one liter. 20 - 40cc of Fujino water was diluted 5 - 10 fold with plain water and administered to the fasting patients perorally. Blood samples were taken from cubital vein before, 1, 2, 4, 6, 24, 48, and 72 hours after the intake of the vitriol water. Copper, zinc, nickel and cobalt contents of the blood samples were measured by Ashizawa' s dithizone- chromatographic method. It was shown that copper, nickel, and cobalt contents of blood rose unexpectedly high temporarily, in a manner that did not correspond to their amount in the given mineral water. So that the mobilization of copper, nickel, and cobalt in the body after the intake of the mineral IVrter was susrected. Zinc content of blood showed no constant tendency.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 15
End Page 17
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002484879
JaLCDOI 10.18926/40343
Title Alternative STUDIES ON VITRIOL SPRINGS (3) EFFECT OF THE INTERNAL USE OF VITRIOL WATER OF FUJINO ON THE GASTRIC ACIDITY
FullText URL pitsr_013_009_014.pdf
Author Morinaga, Hiroshi|
Abstract Fujino Spring is the foremost acid vitriol spring of Japan in ferrous and ferric ion contents. Six years ago the author reported that its internal use had an remarkable hemopoietic effect on hypochromic anemia and delayed the curve of alimentary hyperglycemia in rabbit. Twenty ml. of this vitriol water was diluted with plain water to two hundred ml. and was given to twenty one patients by stomach tube at 37°C. Gastric acidity of the patients was measured at 30 minutes intervals during the following 150 minutes after the administration of the water. In six cases of normal acidity no significant difference was proved between the effects of the mineral water and of caffein control (0.2g. in 200 ml.). In six cases of hyperacidity it seemed that the vitriol water decreased in the acidity curve compared with control. In nine patients of hypo- and anacidity both free and total acidity curve was elevated by the use of the mineral water compared with caffein control. The internal use of Fujino Spring in moderate dilution with plain water regulated the gastric acidity.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 9
End Page 14
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002484879
JaLCDOI 10.18926/40342
Title Alternative ON THE EXISTENCE OF RADIUM B, RADIUM C AND THORIUM B IN MISASA HOT SPRINGS
FullText URL pitsr_013_005_008.pdf
Author Sato, Mitsuo|
Abstract The author tried to measure RaB, RaC and ThB in the hot spring waters using G-M counter and proved the existence of RaB and ThB in Misasa Hot Springs. To 100 liters of spring water ahout 20 gms of ferric chloride and then sodium hydroxide were added. Precipitate was dissolved in hydrochloric acid and after adding bismuth and lead, the solution was saturated with hydrogen sulfide. The precipitate of sulfides was filtered and ignited to ashes after drying. The β-activity of the ashes was measured by a mica-window type G-M counter with the recording circuits of scale of 16. Natural background was 50±5 connts per minutes. Six spring waters of Misasa, namely "Spring of Branch Laboratory", "Nakayu", "Gunze" "O-T-R", "Jwayu", and "Tsukiminoyu" were investigated. RaB was detected in all samples. ThB was found only in "Gunze" and "O-T-R". ThB content of "Gunze" was estimated, to be roughly 1×10(-12) Curie units per liter.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 5
End Page 8
ISSN 0369-7142
language English
File Version publisher
NAID 120002484878
JaLCDOI 10.18926/40341
FullText URL pitsr_013_001_005.pdf
Author Umemoto, Shunji|
Abstract Various colormetric methods for determining magnesium in natural waters have been studied, and the methods using 8-oxyquinolin, ammonium molybdate and titan yellow were studied most frequently(1)), following the studies on the interfering ions(2)). Brilliant yellow(3)), l-amino-2-naphthol-6-sulfonic acid(4)) and other new reagents were also used. E. D. T. A. was used, but the determination by using this reagent is not exact. Present reagent already reported by T. Ashizawa(5)), magneson II, is insoluble in water, soluble in alkali and hardly soluble in ethanol. In the existence of magnesium ion, the color of solution varies from pink-violet (in alkali) and orange (in ethanol) to blue-violet. This variation of color was evaluated photometrically by Shimadzu photoelectric spectrophotometer, and moreover the grades of interference by interfering ions were clarified.
Publication Title 岡山大学温泉研究所報告
Published Date 1953-12
Volume volume13
Start Page 1
End Page 5
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40340
language English
File Version publisher
NAID 120002484877
Author 岡山大学温泉研究所|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author Oshima, Yoshio|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author Seki, Masaji|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author 大島 良雄|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author 淸水 多栄|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author Institute for Thermal Spring Research, Okayama University|
Published Date 1953-12
Publication Title 岡山大学温泉研究所報告
Volume volume13
Content Type Others
Author 岡山大学温泉研究所|
Published Date 1954-03
Publication Title 岡山大学温泉研究所報告
Volume volume14
Content Type Others
JaLCDOI 10.18926/40332
Title Alternative MEDICAL STUDIES ON THE RURAL PEOPLE (II) A STUDY ON THE INCIDENCE OF STRUMA IN THE SOUTH-WESTERN RURAL DISTRICTS OF OKAYAMA PREFECTURE, JAPAN
FullText URL pitsr_014_051_056.pdf
Author Morinaga, Hiroshi|
Abstract The author investigated the thyroid glands of 1480 school children (aged from 6 to 14) living in the vicinity of Yakage, the south-western rural district of Okayama Prefecture, and 1516 out-patients of Yakage Hospital, in 1950. The incidence of struma among the school children was 4.6 per cent and among the out-patients 4.7% on an average, and the percentage of struma in the spring (7.8%) was higher than in the summer (2.98%). This result suggests that thyroid glands are in some way susceptible to seasonal influences, and it is therefore necessary to consider the effect of season during investigation. The white blood pictures of seven patients showed no specific findings.
Publication Title 岡山大学温泉研究所報告
Published Date 1954-03
Volume volume14
Start Page 51
End Page 56
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002462907
JaLCDOI 10.18926/40331
Title Alternative MEDICAL STUDIES ON THE RURAL PEOPLE (I) CLINICAL AND STATISTICAL OBSERVATIONS ON HOOKWORM DISEASE IN RURAL DISTRICTS
FullText URL pitsr_014_045_050.pdf
Author Morinaga, Hiroshi|
Abstract The author studied statistically 160 cases of hookworm infection who had been admitted to Misasa Branch of Okayama University Hospital, Misasa Hot Springs in Tottori prefecture, during 1946~1949 and 162 cases of out-patients with anchylostomiasis in Yakage Hospital, Okayama Prefecture, during 1949~1950. The clinical findings were as follows: (1). Females showed a higher incidence than males and the incidence ratio of infected persons to total out-patients increased with age up to the 50~69 years group. (2). The most patients consulted our hospital for the first time in April~May and in August, and 62 per cent of cases came within 3 months scince they had noticed disorders in some way, but 22% remained at home without medical cure more than a year. (3). Chief subjective complaints were palpitation of heart (35.3%), lassitude of legs (31.2%), pains in the abdomen (22.9%), feeling of dizziness (21.6%) and so on. (4). Laboratory findings: The total number of erythrocytes was between 1.23 and 5.54 millions per cubic millimeter and a moderate anemia almost always developed in the hookworm disease (77.9% of all cases). The number of white cells was normal or slightly increased. Relative or absolute eosinophilia was recognized in 83.5% of all patients. Wassermann's test was positive in 20%, and Takata's reaction positive in 53% of the cases. The acidity of the gastric juice was lower than normal. Hypo- and anacidity were verified in 58%. Both albumen and urobilinogen test in urine were positive in 5.4% of 61 cases. Sugar in none. (5). Treatment: Thymol, tetrachlorethylene and oil of chenopodium were used alternately to remove the worms. The eggs in stool became negative after 3-4 times of the administration of anthelmintics in 76 per cent of 151 cases. As mentioned above, the patients infected with hookworm had various functional disorders of bodies, but they consulted the hospital only when the farmer's busy season began and their trouble became unbearable. And then the recovery of anemia took a month or two. Prof. Kitayama reported that the cold environment under 9°C. in the winter had perished the larva of hookworm in the soil. From these viewpoints, the author proposed that examination and cure of hookworms should be carried out in the winter, the slack season for farming, to prevent the fall of working ability due to anchylostomiasis during the busy farming seasons.
Publication Title 岡山大学温泉研究所報告
Published Date 1954-03
Volume volume14
Start Page 45
End Page 50
ISSN 0369-7142
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/40330
language Japanese
File Version publisher
NAID 120002462906
Author 岡山大学温泉研究所|
Published Date 1954-03
Publication Title 岡山大学温泉研究所報告
Volume volume14
Content Type Others
JaLCDOI 10.18926/40329
Title Alternative DIE ERFAHRUNGEN VON GYNEKOLOGISCHEN BALNEOTHERAPIE (5) DER EINFLUSS VON ORALEN ANWENDUNG VON THERMALWASSER AUF DIE LEBERFUNKTION VON SCHWANGEREN FRAU
FullText URL 014_038_044.pdf
Author Hasegawa, Yasumasa|
Abstract Nach oraler Anwendung vom kochsalzhaitigen schwach radioaktiven Thermalwasser von MISASA 500 ccm bei 20 schwangeren Frauen (meistens S. S. IIM. bis S. S. IVM.) wurden die folgneden Untersuchungen über Leberfunktionen angestellt und mit dem Resultat nach oralen Anwendung von Süsswasser verglichen. 1) Das Thermalwasser steigerte die Zusammensetzungsfähigkeit von Hippursäure d. h· Entgiftungsfähigkeit von Leber. 2) Nach Asorbin S Methode erwies sich keine Veränderung. 3) Die Aussheidungsfähigkeit von Bromsulfalein wurde schwach. 4) 4 stundige Harnmenge nach den oralen Anwendung war weniger bei dem Thermalwasser als bei Süsswasser, und NaCl Menge in beiden Harn war gleich. In Rücksicht auf oben genannten Untersuchungen, trotz des speziellen Einflusses auf die Leberfunktion, wegen antidiuretischer Wirkung darf orale Anwendung des Thermalwassers von MISASA bei schwangeren Frau nur mit einer gewissen Vorsicht gemacht werden.
Publication Title 岡山大学温泉研究所報告
Published Date 1954-03
Volume volume14
Start Page 38
End Page 44
ISSN 0369-7142
language Japanese
File Version publisher
NAID 40017532463
JaLCDOI 10.18926/40328
Title Alternative KLINISCHE UND EXPERIMENTELLE UNTERSUCHUENGN ÜBER DIE WIRKUNG VON THERMALBÄDERN AUF DIE SEXUALFUNKTION VON FRAUEN (6) KONSCHE SILBERREAKTION VON HYPOPHYSEN-HYPOPHYSEN VORDERLAPPEN, OVARIUM UND NEBENNIERE VON RATTE UND DAS THERMALBAD
FullText URL pitsr_014_033_037.pdf
Author Tanaka, Yosinori| Hasegawa, Yasumasa|
Abstract Konsche Siberreaktion (Kon : Silberreaktion der Zellen - Gustav Fischer) ist eine histochemische methode für den Nachweis der Reduktionskraft der Zellen, die von Professor Kon erfunden wurde und im Zusammenhang mit Vitalität der Zellen besonders der endokrinen Organe steht. Also bedeutet die starke Offenbarung dieser Reaktion die gesteigerte Funktion der Gewebe. Um zu forschen ob die geschlechtsfunktion durch Thermalbad beeinflusst wurde, wurde diese Reaktion auf die Hypophysenvorderlappen, Ovarium und Nebenniere der Ratte nach Thermalbad (schwach radioaktive Therme und H2S Therme, 42°C, 5 Minuten lang) angewandt. Sofort nach einmaligem Bad handelte es sich kein Unterschied zwischen Badgruppe und Komtrollgruppe. Nach eimal täglich 50 tägigen Btidern verstaerkte sich die Reaktion von Hypophysenvorderlappen und Corpus luteum von Ovarium (besonders bei H(2)S Therme) aber in anderer Gewebe befand keine Veraenderung sich. Also ist es klar, dass Funktion von Hypophysenvorderlappen und Ovarium nach wiederholten Thermalbaedern sich steigert.
Publication Title 岡山大学温泉研究所報告
Published Date 1954-03
Volume volume14
Start Page 33
End Page 37
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002462905