result 893 件
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ikegawa, Shuntaro| Matsuoka, Ken-ichi| |
| Keywords | regulatory T cell graft-versus-host disease interleukin 2 immune checkpoint inhibitor post-transplant cyclophosphamide |
| Published Date | 2021-08-30 |
| Publication Title | Frontiers In Immunology |
| Volume | volume12 |
| Publisher | Frontiers Media SA |
| Start Page | 713358 |
| ISSN | 1664-3224 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Ikegawa and Matsuoka. |
| File Version | publisher |
| PubMed ID | 34526990 |
| DOI | 10.3389/fimmu.2021.713358 |
| Web of Science KeyUT | 000698797000001 |
| Related Url | isVersionOf https://doi.org/10.3389/fimmu.2021.713358 |
| FullText URL | fulltext20210924-1.pdf |
|---|---|
| Author | Ho, Dung Thi| Pham, Hung Hoang Son| Aota, Wataru| Matsubayashi, Makoto| Tsuji, Naotoshi| Hatabu, Toshimitsu| |
| Keywords | Eimeria tenella Local immune response Macrophage |
| Note | © 2021 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 License.http://creativecommons.org/licenses/by-nc-nd/4.0/.This is the accepted manuscript version. The formal published version is available at https://doi.org/10.1016/j.rvsc.2021.07.003. | |
| Published Date | 2021-10 |
| Publication Title | Research in Veterinary Science |
| Volume | volume139 |
| Publisher | Elsevier BV |
| ISSN | 0034-5288 |
| NCID | AA00816614 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Elsevier Ltd. |
| File Version | author |
| PubMed ID | 34252703 |
| DOI | 10.1016/j.rvsc.2021.07.003 |
| Web of Science KeyUT | 000692610100009 |
| Related Url | isVersionOf https://doi.org/10.1016/j.rvsc.2021.07.003 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Hutami, Islamy Rahma| Izawa, Takashi| Khurel-Ochir, Tsendsuren| Sakamaki, Takuma| Iwasa, Akihiko| Tanaka, Eiji| |
| Keywords | HIF1 M1/M2 macrophage S1P wound healing |
| Published Date | 2021-08-20 |
| Publication Title | International Journal of Molecular Sciences |
| Volume | volume22 |
| Issue | issue16 |
| Publisher | MDPI |
| Start Page | 8992 |
| ISSN | 1422-0067 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34445695 |
| DOI | 10.3390/ijms22168992 |
| Web of Science KeyUT | 000689169900001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijms22168992 |
| JaLCDOI | 10.18926/AMO/62378 |
|---|---|
| FullText URL | 75_4_403.pdf |
| Author | Matoba, Ryo| Morizane, Yuki| |
| Abstract | Epiretinal membrane (ERM) is a common retinal disease characterized by cellular proliferation and metaplasia that lead to the formation of a pathological fibrocellular membrane immediately superjacent to the inner retinal surface. The vast majority of ERMs are considered idiopathic. However, ERM formation can result from various primary intraocular diseases, including retinal breaks and detachment, retinal vascular diseases, and vitreoretinal inflammatory conditions. Although ERMs are generally asymptomatic or cause mild metamorphopsia and/or a modest decrease in visual acuity, some can cause severe macular distortion and macular edema, resulting in significantly impaired function. Surgical removal of ERM is the only treatment, and improvements in vitrectomy systems have enabled less invasive treatment. However, there are currently no standardized criteria for ERM surgery, and the indications for surgery are determined from the patient’s subjective symptoms. Another problem with ERM surgery is that not all patients show satisfactory postoperative recovery of visual function. Thus, further research is needed to determine the criteria for ERM surgery and methods to improve the postoperative prognosis. |
| Keywords | epiretinal membrane vitrectomy optical coherence tomography internal limiting membrane lamellar macular hole |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-08 |
| Volume | volume75 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 403 |
| End Page | 413 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34511606 |
| Web of Science KeyUT | 000697944600001 |
| NAID | 120007146059 |
| FullText URL | fulltext20210824-3.pdf |
|---|---|
| Author | Yamaguchi, Takahiro| Yoshimura, Teizo| Ohara, Toshiaki| Fujisawa, Masayoshi| Tong, Gao| Matsukawa, Akihiro| |
| Keywords | Toll-like receptors cell migration metastasis epithelial mesenchymal transformation |
| Note | This is a post-peer-review, pre-copyedit version of an article published in Molecular Biology Reports. The final authenticated version is available online at: https://doi.org/10.1007/s11033-021-06625-1| |
| Published Date | 2021-8-14 |
| Publication Title | Molecular Biology Reports |
| Publisher | Springer Science and Business Media LLC |
| ISSN | 0301-4851 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 34390443 |
| DOI | 10.1007/s11033-021-06625-1 |
| Web of Science KeyUT | 000684897400002 |
| Related Url | isVersionOf https://doi.org/10.1007/s11033-021-06625-1 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Abu Quora, Hagar A.| Zahra, Maram H.| El-Ghlban, Samah| Nair, Neha| Afify, Said M.| Hassan, Ghmkin| Nawara, Hend M.| Sheta, Mona| Monzur, Sadia| Fu, Xiaoying| Osman, Amira| Seno, Akimasa| Seno, Masaharu| |
| Keywords | Mammary fat pad microenvironment iPSCs CSCs breast cancer |
| Published Date | 2021 |
| Publication Title | American Journal of Cancer Research |
| Volume | volume11 |
| Issue | issue7 |
| Publisher | e-Century Publishing Corp. |
| Start Page | 3475 |
| End Page | 3495 |
| ISSN | 2156-6976 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | AJCR (c)2021 e-Century Publishing Corp. |
| File Version | publisher |
| PubMed ID | 34354856 |
| Web of Science KeyUT | 000680048600006 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nakamura, Makoto| Meguri, Yusuke| Ikegawa, Shuntaro| Kondo, Takumi| Sumii, Yuichi| Fukumi, Takuya| Iwamoto, Miki| Sando, Yasuhisa| Sugiura, Hiroyuki| Asada, Noboru| Ennishi, Daisuke| Tomida, Shuta| Fukuda-Kawaguchi, Emi| Ishii, Yasuyuki| Maeda, Yoshinobu| Matsuoka, Ken-Ichi| |
| Published Date | 2021-06-23 |
| Publication Title | Scientific Reports |
| Volume | volume11 |
| Issue | issue1 |
| Publisher | Nature Research |
| Start Page | 13125 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2021 |
| File Version | publisher |
| PubMed ID | 34162921 |
| DOI | 10.1038/s41598-021-92526-z |
| Web of Science KeyUT | 000669995600012 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-021-92526-z |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsuda, Tatsuo| Umeda, Yuzo| Matsuda, Tadakazu| Endo, Yoshikatsu| Sato, Daisuke| Kojima, Toru| Sui, Kenta| Inagaki, Masaru| Ota, Tetsuya| Hioki, Masayoshi| Oishi, Masahiro| Kimura, Masashi| Murata, Toshihiro| Ishido, Nobuhiro| Yagi, Takahito| Fujiwara, Toshiyoshi| |
| Keywords | Intrahepatic cholangiocarcinoma Postoperative complication Prognostic nutritional index |
| Published Date | 2021-06-16 |
| Publication Title | BMC Cancer |
| Volume | volume21 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 708 |
| ISSN | 1471-2407 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s). 2021 |
| File Version | publisher |
| PubMed ID | 34130648 |
| DOI | 10.1186/s12885-021-08424-0 |
| Web of Science KeyUT | 000664089600001 |
| Related Url | isVersionOf https://doi.org/10.1186/s12885-021-08424-0 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kageyama, Misaki| Hagiya, Hideharu| Ueda, Yasutaka| Ohtani, Katsuki| Fukumori, Yasuo| Inoue, Norimitsu| Wakamiya, Nobutaka| Yoneda, Nanoka| Kimura, Keigo| Nagasawa, Motonori| Nakagami, Futoshi| Nishi, Isao| Sugimoto, Ken| Rakugi, Hiromi| |
| Keywords | complement addition test complement deficiency disseminated gonococcal infection genome analysis Neisseria gonorrhoeae sexually transmitted infection |
| Published Date | 2021-04-02 |
| Publication Title | Medicine |
| Volume | volume100 |
| Issue | issue13 |
| Publisher | LIPPINCOTT WILLIAMS & WILKINS |
| Start Page | e25265 |
| ISSN | 0025-7974 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 the Author(s). |
| File Version | publisher |
| PubMed ID | 33787610 |
| DOI | 10.1097/MD.0000000000025265 |
| NAID | 120007098535 |
| Web of Science KeyUT | 000658960700045 |
| Related Url | isVersionOf https://doi.org/10.1097/MD.0000000000025265 |
| JaLCDOI | 10.18926/AMO/62237 |
|---|---|
| FullText URL | 75_3_397.pdf |
| Author | Sekito, Takanori| Takamoto, Atsushi| Kobayashi, Yasuyuki| Mitsui, Masao| Watari, Shogo| Kubota, Risa| Sadahira, Takuya| Iwata, Takehiro| Nishimura, Shingo| Edamura, Kohei| Sako, Tomoko| Araki, Motoo| Watanabe, Masami| Watanabe, Toyohiko| Shibata, Rei| Ennishi, Daisuke| Nasu, Yasutomo| |
| Abstract | We report a 62-year-old male with metastatic fumarate hydratase-deficient renal cell carcinoma (FH-deficient RCC) without fumarate hydratase (FH) mutation (FH-deficient–like RCC). The International Metastatic RCC Database Consortium risk score was intermediate, and immunotherapy with nivolumab and ipilimumab (Ipi/ Nivo) was initiated. Four cycles of Ipi/Nivo and 5 cycles of nivolumab resulted in a complete response of the metastases. Hypophysitis occurred as an immune-related adverse event after four cycles of Ipi/Nivo. The prognosis of patients with FH-deficient RCC is generally poor. Few reports of FH-deficient RCC successfully treated with Ipi/Nivo have been published. Ipi/Nivo can be effective for treating FH-deficient RCC. |
| Keywords | fumarate hydratase fumarate hydratase-deficient renal cell carcinoma renal cell carcinoma ipilimumab nivolumab |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-06 |
| Volume | volume75 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 397 |
| End Page | 402 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34176946 |
| Web of Science KeyUT | 000667147700017 |
| NAID | 120007089822 |
| JaLCDOI | 10.18926/AMO/62228 |
|---|---|
| FullText URL | 75_3_335.pdf |
| Author | Chikuie, Nobuyuki| Hamamoto, Takao| Ueda, Tsutomu| Taruya, Takayuki| Kono, Takashi| Furuie, Hiromi| Ishino, Takashi| Takeno, Sachio| |
| Abstract | Recurrent or metastatic head and neck squamous cell carcinoma (R/MHNSCC) has a poor prognosis. Although nivolumab is approved in Japan for treating R/MHNSCC, the response rate is low. Therefore, identifying pretreatment prognostic factors is necessary. This study assessed the utility of the neutrophil-to-lymphocyte ratio (NLR) and Glasgow Prognostic Score (GPS) as biomarkers of response to nivolumab. We retrospectively collected the data of 56 R/MHNSCC patients treated with nivolumab between May 2017 and December 2019. The Kaplan–Meier method and log-rank test were used to estimate overall survival (OS) and progression-free survival (PFS), and multivariate Cox hazard regression analysis was used to identify independent predictors of survival. Patients with a low pretreatment NLR had prolonged OS, and patients with a low pretreatment GPS had increased OS and PFS. A performance score (PS) of 0-1, development of immune-related adverse events, and GPS of 0-1 were significantly associated with OS in multivariate analysis. In summary, baseline pretreatment NLR and GPS are independently associated with OS in R/MHNSCC patients treated with nivolumab. Administration of nivolumab while maintaining the PS reflects a immune status of the host and leads to a good OS. |
| Keywords | neutrophil-to-lymphocyte ratio nivolumab Glasgow Prognostic Score recurrent or metastatic head and neck squamous cell carcinoma (R/MHNSCC) |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-06 |
| Volume | volume75 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 335 |
| End Page | 343 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34176937 |
| Web of Science KeyUT | 000667147700008 |
| NAID | 120007089825 |
| JaLCDOI | 10.18926/AMO/62219 |
|---|---|
| FullText URL | 75_3_279.pdf |
| Author | Nishinohara, Masa-aki| Nishimori, Hisakazu| Fujiwara, Hideaki| Asada, Noboru| Ennishi, Daisuke| Matsuoka, Ken-ichi| Fujii, Keiko| Fujii, Nobuharu| Maeda, Yoshinobu| |
| Abstract | A bloodstream infection (BSI) is the most common serious infectious complication of hematopoietic stem cell transplantation (HSCT). BSI promotes an inflammatory state, which exacerbates acute graft-versus-host disease (GVHD). We investigated whether a Gram-negative rod bloodstream infection (GNR-BSI), which develops early after allo-HSCT, affected the onset or exacerbated acute GVHD in 465 patients who underwent allo-HSCT from 1995 through 2015 at a single institution. Eighty-eight patients (19%) developed BSI during the study period. Among the cultures, 50 (57%) were Gram-positive cocci (GPC) and 31 (35%) were GNR. Of the 465 patients, 187 (40%) developed acute GVHD of grade II or higher within the first 100 days post-allogeneic HSCT: 124 (27%) had acute GVHD grade II, 47 (10%) had grade III, and 16 (3%) had grade IV. Multivariate analysis revealed that GNR-BSI was a significant risk factor for grade II-IV acute GVHD (grade II-IV: hazard ratio [HR] 1.75, 95% confidence interval [CI] 1.03-2.97; grade III-IV: HR 2.37, 95% CI 1.03-5.43). These results suggest that GNR-BSI may predict the onset and exacerbation of acute GVHD. |
| Keywords | blood stream infection graft-versus-host disease gram negative rods |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-06 |
| Volume | volume75 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 279 |
| End Page | 287 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34176931 |
| Web of Science KeyUT | 000667147700003 |
| NAID | 120007089834 |
| JaLCDOI | 10.18926/AMO/62218 |
|---|---|
| FullText URL | 75_3_269.pdf |
| Author | Katsui, Kuniaki| Ogata, Takeshi| Watanabe, Kenta| Yoshio, Kotaro| Kuroda, Masahiro| Hiraki, Takao| Kiura, Katsuyuki| Maeda, Yoshinobu| Toyooka, Shinichi| Kanazawa, Susumu| |
| Abstract | Palliative concurrent chemoradiotherapy (CCRT) is often administered to patients with stage III non-small cell lung cancer (NSCLC). We investigated the clinical outcomes of patients receiving palliative CCRT for NSCLC. Data of patients with NSCLC who underwent palliative CCRT (n=16), preoperative CCRT plus surgery (n=97), or definitive CCRT (n=48) were evaluated. In all groups, the concurrent chemotherapy regimens consisted of cisplatin and docetaxel. Rates of local control (LC), distant metastasis-free survival (DMFS), progression-free survival (PFS), overall survival (OS), and prognosis were compared. The 2-year rates of LC, DMFS, PFS, and OS in 16 patients who underwent palliative CCRT were 44.4%, 12.5%, 12.5%, and 18.8%, respectively. Univariate analysis showed that palliative CCRT was associated with poor LC (p<0.001), DMFS (p<0.001), PFS (p<0.001), and OS (p<0.001) outcomes in patients who completed CCRT as a preoperative treatment and poor LC (p=0.01), DMFS (p=0.003), PFS (p=0.04), and OS (p=0.004) outcomes in patients who were considered for definitive CCRT. Although there were some long-term survivors, the clinical outcomes of palliative CCRT were significantly inferior to those of the ideal treatments. Therefore, careful determination of the appropriate treatment indications and further studies are warranted. |
| Keywords | palliative concurrent chemoradiotherapy cisplatin/docetaxel stage III non-small cell lung cancer |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-06 |
| Volume | volume75 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 269 |
| End Page | 277 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34176930 |
| Web of Science KeyUT | 000667147700002 |
| NAID | 120007089833 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yoshinaga, Kasumi| Araki, Motoo| Wada, Koichiro| Sekito, Takanori| Watari, Shogo| Maruyama, Yuki| Mitsui, Yosuke| Sadahira, Takuya| Kubota, Risa| Nishimura, Shingo| Edamura, Kohei| Kobayashi, Yasuyuki| Tanabe, Katsuyuki| Takeuchi, Hidemi| Kitagawa, Masashi| Kitamura, Shinji| Wada, Jun| Watanabe, Masami| Watanabe, Toyohiko| Nasu, Yasutomo| |
| Keywords | diabetes mellitus kidney function kidney transplantation marginal donor |
| Published Date | 2021-06-08 |
| Publication Title | Immunity Inflammation and Disease |
| Publisher | Wiley |
| ISSN | 2050-4527 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Authors. |
| File Version | publisher |
| PubMed ID | 34102025 |
| DOI | 10.1002/iid3.470 |
| NAID | 120007053366 |
| Web of Science KeyUT | 000658836600001 |
| Related Url | isVersionOf https://doi.org/10.1002/iid3.470 |
| FullText URL | K0006422_abstract_review.pdf K0006422_fulltext.pdf |
|---|---|
| Author | Sakai, Shunsuke| |
| Published Date | 2021-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6422号 |
| Granted Date | 2021-03-25 |
| Thesis Type | Doctor of Philosophy in Agriculture |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Ishii, Hiroko| Afify, Said M.| Hassan, Ghmkin| Salomon, David S.| Seno, Masaharu| |
| Keywords | Cripto-1 TGF-beta cancer stem cells immunotherapy antibody |
| Published Date | 2021-05-20 |
| Publication Title | Cancers |
| Volume | volume13 |
| Issue | issue10 |
| Publisher | MDPI |
| Start Page | 2491 |
| ISSN | 2072-6694 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| DOI | 10.3390/cancers13102491 |
| NAID | 120007042393 |
| Web of Science KeyUT | 000654727400001 |
| Related Url | isVersionOf https://doi.org/10.3390/cancers13102491 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Morichika, Daisuke| Taniguchi, Akihiko| Oda, Naohiro| Fujii, Utako| Senoo, Satoru| Itano, Junko| Kanehiro, Arihiko| Kitaguchi, Yoshiaki| Yasuo, Masanori| Hanaoka, Masayuki| Satoh, Takashi| Akira, Shizuo| Kiura, Katsuyuki| Maeda, Yoshinobu| Miyahara, Nobuaki| |
| Keywords | Chronic obstructive pulmonary disease COPD HGF VEGF |
| Published Date | 2021-05-15 |
| Publication Title | Respiratory Research |
| Volume | volume22 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 150 |
| ISSN | 1465-993X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2021. |
| File Version | publisher |
| PubMed ID | 33992109 |
| DOI | 10.1186/s12931-021-01705-z |
| Web of Science KeyUT | 000650826300001 |
| Related Url | isVersionOf https://doi.org/10.1186/s12931-021-01705-z |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sugiura, Hiroyuki| Matsuoka, Ken-Ichi| Fukumi, Takuya| Sumii, Yuichi| Kondo, Takumi| Ikegawa, Shuntaro| Meguri, Yusuke| Iwamoto, Miki| Sando, Yasuhisa| Nakamura, Makoto| Toji, Tomohiro| Ishii, Yasuyuki| Maeda, Yoshinobu| |
| Keywords | chronic graft-versus-host disease hematopoietic stem cell transplantation iNKT cells regulatory T cells Tfh cells alpha-galactosylceramide |
| Published Date | 2021-05-04 |
| Publication Title | Immunity Inflammation and Disease |
| Publisher | Wiley |
| ISSN | 2050-4527 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 The Authors. |
| File Version | publisher |
| PubMed ID | 33942544 |
| DOI | 10.1002/iid3.425 |
| NAID | 120007037388 |
| Web of Science KeyUT | 000646539700001 |
| Related Url | isVersionOf https://doi.org/10.1002/iid3.425 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Lin, Wenfeng| Li, Chaoming| Xu, Naijin| Watanabe, Masami| Xue, Ruizhi| Xu, Abai| Araki, Motoo| Sun, Ruifen| Liu, Chunxiao| Nasu, Yasutomo| Huang, Peng| |
| Keywords | prostate cancer PLGA indocyanine green resiquimod photothermal therapy immunotherapy |
| Published Date | 2021-04-12 |
| Publication Title | International Journal of Nanomedicine |
| Volume | volume16 |
| Publisher | Dove Medical Press Ltd. |
| Start Page | 2775 |
| End Page | 2787 |
| ISSN | 1178-2013 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Lin et al. |
| File Version | publisher |
| PubMed ID | 33880023 |
| DOI | 10.2147/IJN.S301552 |
| NAID | 120007034434 |
| Web of Science KeyUT | 000639251200001 |
| Related Url | isVersionOf https://doi.org/10.2147/IJN.S301552 |
| JaLCDOI | 10.18926/AMO/61906 |
|---|---|
| FullText URL | 75_2_231.pdf |
| Author | Endo, Motochika| Yano, Shuya| Asano, Hiroaki| Takeda, Sho| Hamada, Yuki| Kondo, Yoshitaka| Kuroda, Shinji| Shigeyasu, Kunitoshi| Kikuchi, Satoru| Tanaka, Takehiro| Teraishi, Fuminori| Nishizaki, Masahiko| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| |
| Abstract | Targeted therapies for malignant melanoma have improved patients’ prognoses. A primary gastrointestinal malignant melanoma is very rare, with no standard treatment strategy. We treated a 78-year-old Japanese female with advanced primary gastrointestinal melanoma of the descending colon and gallbladder. We administered a multidisciplinary treatment: surgical resection of the descending colon and gallbladder tumors, resection of the metastatic lymph nodes behind the pancreas head, and immune checkpoint antibody-blockade therapy (nivolumab) for ~4 years. PET/CT demonstrated no recurrent lesion for > 3 years. Multidisciplinary therapies (e.g., surgery, chemotherapy, radiotherapy, target therapy, and immune checkpoint antibody-blockade therapy) can successfully treat primary gastrointestinal malignant melanoma. |
| Keywords | primary gastrointestinal melanoma laparoscopic surgery immune checkpoint antibody-blockade inhibitor |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-04 |
| Volume | volume75 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 231 |
| End Page | 238 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 33953431 |
| NAID | 120007029881 |
