| ID | 53479 |
| FullText URL | |
| Title Alternative | Studies on the molecular evolution (affinity maturation) of antibodies: unexpected encounter
|
| Author |
Ohmori, Hitoshi
|
| Abstract | Antibodies are unique proteins in that they improve their affinity for antigens during
antibody responses. This process termed “affinity maturation” is the result of random
hypermutation of immunoglobulin genes in B cells followed by selection of the clones that acquired
high-affinity antibodies. However, what mechanisms are responsible for the induction of
hypermutation and the subsequent B cell selection in germinal centers has remained unknown in
many respects. I would like to talk about our long-lasting studies on these immunologic
mechanisms focusing on the functional role of follicular dendritic cells
|
| Note | 記念講演要旨 (Summary of Commemorational Lecture)
|
| Published Date | 2015-04
|
| Publication Title |
岡山実験動物研究会報
|
| Publication Title Alternative | Proceedings of Okayama Association for Laboratory Animal Science
|
| Volume | volume31
|
| Publisher | 岡山実験動物研究会
|
| Publisher Alternative | Okayama Association for Laboratory Animal Science
|
| Start Page | 2
|
| End Page | 3
|
| Content Type |
Others
|
| language |
Japanese
|
| File Version | publisher
|
| Refereed |
False
|
| Eprints Journal Name | poalas
|
