| FullText URL | fulltext.pdf |
|---|---|
| Author | Iwamuro, Masaya| Tanaka, Takehiro| Kagawa, Shunsuke| Inoo, Shoko| Otsuka, Motoyuki| |
| Keywords | immune checkpoint inhibitor chemotherapy-induced diarrhea immune-related adverse event colitis colonoscopy collagenous colitis |
| Published Date | 2023-05-25 |
| Publication Title | Cureus |
| Volume | volume15 |
| Issue | issue5 |
| Publisher | Springer |
| Start Page | e39466 |
| ISSN | 2168-8184 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 Iwamuro et al. |
| File Version | publisher |
| PubMed ID | 37378156 |
| DOI | 10.7759/cureus.39466 |
| Web of Science KeyUT | 001023091300016 |
| Related Url | isVersionOf https://doi.org/10.7759/cureus.39466 |
| JaLCDOI | 10.18926/AMO/65488 |
|---|---|
| FullText URL | 77_3_235.pdf |
| Author | Kuraoka, Sakiko| Iwamuro, Masaya| Satomi, Takuya| Yamazaki, Tatsuhiro| Hamada, Kenta| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kato, Hironari| Otsuka, Fumio| Okada, Hiroyuki| |
| Abstract | Changes in hormone levels in patients with cancer cachexia after anamorelin administration have not been fully investigated. This study aimed to determine how anamorelin affects the endocrine system in patients with gastrointestinal cancer and cachexia. We prospectively enrolled 13 patients and comprehensively investigated their body weight and levels of serum albumin, hemoglobin A1c (HbA1c), and hormones before (week 0) and 3 and 12 weeks after anamorelin administration. The variables were evaluated at week 3 in 9 patients and at week 12 in 5 patients. At week 3, anamorelin administration resulted in body weight gain and increased the levels of growth hormone and HbA1c, as well as insulin-like growth factor-1 standard deviation scores (IGF-1 SD scores). At the same time, negative correlations were observed between ΔIGF-1 SD score and Δthyroidstimulating hormone (TSH) and between ΔIGF-1 SD score and Δfree testosterone. ΔBody weight and ΔIGF-1 SD score correlated positively at week 12. These results suggest that TSH and free testosterone levels can be affected 3 weeks after anamorelin administration; however, those variables tend to return to a state of equilibrium, and anabolic effects of anamorelin appear in long-term (≥ 12 weeks) users. |
| Keywords | anamorelin body weight cancer cachexia endocrine system |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-06 |
| Volume | volume77 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 235 |
| End Page | 241 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37357624 |
| Web of Science KeyUT | 001026279600001 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Iwamuro, Masaya| Tanaka, Takehiro| Okada, Hiroyuki| |
| Keywords | Diagnosis Diffuse large B-cell lymphoma Duodenal neoplasms Esoph-agogastroduodenoscopy Follicular lymphoma Gastrointestinal lymphoma |
| Published Date | 2023-03-28 |
| Publication Title | World Journal of Gastroenterology |
| Volume | volume29 |
| Issue | issue12 |
| Publisher | Baishideng Publishing Group |
| Start Page | 1852 |
| End Page | 1862 |
| ISSN | 1007-9327 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023. |
| File Version | publisher |
| PubMed ID | 37032723 |
| DOI | 10.3748/wjg.v29.i12.1852 |
| Web of Science KeyUT | 000982154800007 |
| Related Url | isVersionOf https://doi.org/10.3748/wjg.v29.i12.1852 |
| FullText URL | fulltext20230530-03.pdf |
|---|---|
| Author | Iwamuro, Masaya| Kusumoto, Chiaki| Nakagawa, Masahiro| Matsueda, Kazuhiro| Kobayashi, Sayo| Yoshioka, Masao| Inaba, Tomoki| Toyokawa, Tatsuya| Sakaguchi, Chihiro| Tanaka, Shouichi| Tanaka, Takehiro| Okada, Hiroyuki| |
| Keywords | Gastric adenocarcinoma of the fundic gland type (GA-FG) gastric neoplasms oxyntic gland adenoma submucosal invasion |
| Published Date | 2023-03-16 |
| Publication Title | Journal of Gastrointestinal Oncology |
| Volume | volume14 |
| Issue | issue2 |
| Publisher | AME Publishing Company |
| Start Page | 554 |
| End Page | 562 |
| ISSN | 2078-6891 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Journal of Gastrointestinal Oncology. |
| File Version | publisher |
| PubMed ID | 37201070 |
| DOI | 10.21037/jgo-22-870 |
| Web of Science KeyUT | 000992116200001 |
| Related Url | isVersionOf https://dx.doi.org/10.21037/jgo-22-870 |
| Title Alternative | A case of duodenal diverticulitis in a patient receiving tocilizumab for rheumatoid arthritis |
|---|---|
| FullText URL | 134_166.pdf |
| Author | Iwamuro, Masaya| Baba, Yuki| Kawahara, Yoshiro| Okada, Hiroyuki| |
| Abstract | A Japanese woman was diagnosed with rheumatoid arthritis at the age of 41. At the age of 56, her rheumatoid arthritis worsened and a subcutaneous injection of tocilizumab and oral prednisolone was administered, which led to an improvement of arthritis. At the age of 57, right lower abdominal pain and vomiting suddenly appeared. Abdominal computed tomography showed a parapapillary diverticulum in the descending duodenum. The diverticulum was filled with residue, and an inflammation of the surrounding adipose tissue was observed; no free air was found. The patient was diagnosed with duodenal diverticulitis and treated with antibiotics, which resulted in an uneventful recovery. The maximum value of CRP was 1.88㎎/dL on the third day of hospitalization. Esophagogastroduodenoscopy performed on the 8th day of hospitalization revealed a parapapillary diverticulum with adhesion of pus and redness of the mucosa at the opening of the diverticulum, consistent with diverticulitis. This case highlights that diverticulitis in infrequent areas such as the duodenum may occur in patients who are treated with tocilizumab. In addition, inflammation of diverticulitis may be underestimated because abnormal laboratory values such as those induced by inflammatory reactions are less likely to occur during tocilizumab treatment. |
| Keywords | トシリズマブ（tocilizumab） 十二指腸憩室（duodenal diverticulum） 憩室炎（diverticulitis） |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2022-12-01 |
| Volume | volume134 |
| Issue | issue3 |
| Start Page | 166 |
| End Page | 170 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.134.166 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2022 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.134.166 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Iwamuro, Masaya| Takahashi, Takahide| Hirabata, Araki| Tanaka, Takehiro| Otsuka, Fumio| Okada, Horoyuki| |
| Keywords | carcinogenesis lymphocytes helicobacter pylori gastric adenocarcinoma flow cytometry |
| Published Date | 2022-11-20 |
| Publication Title | Cureus Journal Of Medical Science |
| Volume | volume14 |
| Issue | issue11 |
| Publisher | Cureus Inc. |
| Start Page | e31713 |
| ISSN | 2168-8184 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 Iwamuro et al. |
| File Version | publisher |
| PubMed ID | 36569708 |
| DOI | 10.7759/cureus.31713 |
| Web of Science KeyUT | 000918257500029 |
| Related Url | isVersionOf https://doi.org/10.7759/cureus.31713 |
| JaLCDOI | 10.18926/AMO/64365 |
|---|---|
| FullText URL | 77_1_75.pdf |
| Author | Iwamuro, Masaya| Tanaka, Takehiro| Hamada, Kenta| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kawano, Seiji| Kawahara, Yoshiro| Okada, Hiroyuki| |
| Abstract | Herein, we report two patients with autoimmune gastritis who had undergone multiple esophagogastroduodenoscopy procedures for 17 and 9 years, respectively, before their diagnosis. Instead, they had been diagnosed with and treated for Helicobacter pylori-associated gastritis. The correct diagnosis was made when scatterings of tiny whitish protrusions in the gastric mucosa were detected on esophagogastroduodenoscopy. Our findings suggest that scattered tiny whitish bumps may be a clue to the diagnosis of autoimmune gastritis. |
| Keywords | autoimmune gastritis esophagogastroduodenoscopy scattered lesions small white protrusions mucosal lesions |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-02 |
| Volume | volume77 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 75 |
| End Page | 80 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 36849149 |
| Web of Science KeyUT | 000952973200001 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Iwamuro, Masaya| Tanaka, Takehiro| Kono, Yoshiyasu| Kawano, Seiji| Okada, Horoyuki| |
| Keywords | nivolumab ipilimumab immune -related adverse events immune checkpoint inhibitor esophagogastroduodenoscopy |
| Published Date | 2022-12-19 |
| Publication Title | CUREUS JOURNAL OF MEDICAL SCIENCE |
| Volume | volume14 |
| Issue | issue12 |
| Publisher | Cureus |
| Start Page | e32710 |
| ISSN | 2168-8184 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 Iwamuro et al. |
| File Version | publisher |
| PubMed ID | 36686096 |
| DOI | 10.7759/cureus.32710 |
| Web of Science KeyUT | 000905471200003 |
| Related Url | isVersionOf https://doi.org/10.7759/cureus.32710 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Iwamuro, Masaya| Tanaka, Takehiro| Matsumura, Akifumi| Kawano, Seiji| Kawahara, Yoshiro| Okada, Hiroyuki| |
| Published Date | 2022-12-31 |
| Publication Title | Case Reports In Gastrointestinal Medicine |
| Volume | volume2022 |
| Publisher | Hindawi Ltd |
| Start Page | 4637707 |
| ISSN | 2090-6528 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 Masaya Iwamuro et al. |
| File Version | publisher |
| PubMed ID | 36624891 |
| DOI | 10.1155/2022/4637707 |
| Web of Science KeyUT | 000910999400001 |
| Related Url | isVersionOf https://doi.org/10.1155/2022/4637707 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kobashi, Mayu| Iwamuro, Masaya| Kuraoka, Sakiko| Inoo, Shoko| Okanoue, Shotaro| Satomi, Takuya| Hamada, Kenta| Abe, Makoto| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kawano, Seiji| Tanaka, Takehiro| Kawahara, Yoshiro| Okada, Hiroyuki| |
| Keywords | familial adenomatous polyposis gastric adenoma gastric cancer phenotypic variations |
| Published Date | 2022-10-14 |
| Publication Title | Medicine |
| Volume | volume101 |
| Issue | issue41 |
| Publisher | Lippincott Williams & Wilkins |
| Start Page | e30997 |
| ISSN | 0025-7974 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 the Author(s). |
| File Version | publisher |
| PubMed ID | 36254079 |
| DOI | 10.1097/MD.0000000000030997 |
| Web of Science KeyUT | 000868085500032 |
| Related Url | isVersionOf https://doi.org/10.1097/MD.0000000000030997 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Iwamuro, Masaya| Takahashi, Takahide| Watanabe, Natsuki| Abe, Makoto| Sakae, Hiroyuki| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Tanaka, Takehiro| Kawano, Seiji| Otsuka, Fumio| Kawahara, Yoshiro| Yanai, Hiroyuki| Okada, Hiroyuki| |
| Keywords | eradication flow cytometry Helicobacter pylori T lymphocytes |
| Published Date | 2022-08-26 |
| Publication Title | Medicine |
| Volume | volume101 |
| Issue | issue34 |
| Publisher | Lippincott Williams & Wilkins |
| Start Page | e30241 |
| ISSN | 0025-7974 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 the Author(s). |
| File Version | publisher |
| PubMed ID | 36042652 |
| DOI | 10.1097/MD.0000000000030241 |
| Web of Science KeyUT | 000847532100050 |
| Related Url | isVersionOf https://doi.org/10.1097/MD.0000000000030241 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Iwamuro, Masaya| Murayama, Somay Yamagata| Nakamura, Masahiko| Hamada, Kenta| Tanaka, Takehiro| Okada, Hiroyuki| |
| Published Date | 2022-07-20 |
| Publication Title | Case Reports In Gastrointestinal Medicine |
| Volume | volume2022 |
| Publisher | Hindawi Ltd |
| Start Page | 4254605 |
| ISSN | 2090-6528 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 Masaya Iwamuro et al. |
| File Version | publisher |
| PubMed ID | 35911659 |
| DOI | 10.1155/2022/4254605 |
| Web of Science KeyUT | 000853251100001 |
| Related Url | isVersionOf https://doi.org/10.1155/2022/4254605 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Iwamuro, Masaya| Tanaka, Takehiro| Kuraoka, Sakiko| Hamada, Kenta| Abe, Makoto| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kawano, Seiji| Kawahara, Yoshiro| Okada, Hiroyuki| |
| Keywords | esophagogastroduodenoscopy gastric erosion gastric ulcer zinc acetate dihydrate |
| Published Date | 2022-07-01 |
| Publication Title | Internal Medicine |
| Volume | volume61 |
| Issue | issue13 |
| Publisher | The Japanese Society of Internal Medicine |
| Start Page | 1931 |
| End Page | 1938 |
| ISSN | 0918-2918 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 The Japanese Society of Internal Medicine |
| File Version | publisher |
| PubMed ID | 35781269 |
| DOI | 10.2169/internalmedicine.8625-21 |
| Web of Science KeyUT | 000823060200001 |
| Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.8625-21 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kametaka, Daisuke| Iwamuro, Masaya| Takahashi, Takahide| Hirabata, Araki| Hamada, Kenta| Kono, Yoshiyasu| Kanzaki, Hiromitsu| Kawano, Seiji| Tanaka, Takehiro| Otsuka, Fumio| Kawahara, Yoshiro| Okada, Hiroyuki| |
| Keywords | flow cytometry autoimmune gastritis atrophic gastritis Helicobacter pylori |
| Published Date | 2022-05-25 |
| Publication Title | Current Issues In Molecular Biology |
| Volume | volume44 |
| Issue | issue6 |
| Publisher | MDPI |
| Start Page | 2443 |
| End Page | 2452 |
| ISSN | 1467-3037 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 35735608 |
| DOI | 10.3390/cimb44060167 |
| Web of Science KeyUT | 000816477400001 |
| Related Url | isVersionOf https://doi.org/10.3390/cimb44060167 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Iwamuro, Masaya| Kusumoto, Chiaki| Nakagawa, Masahiro| Matsueda, Kazuhiro| Kobayashi, Sayo| Yoshioka, Masao| Inaba, Tomoki| Toyokawa, Tatsuya| Sakaguchi, Chihiro| Tanaka, Shouichi| Tanaka, Takehiro| Okada, Hiroyuki| |
| Keywords | Gastric neoplasms Oxyntic gland adenoma Gastric adenocarcinoma of the fundic gland type |
| Published Date | 2022-06-12 |
| Publication Title | BMC Gastroenterology |
| Volume | volume22 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 294 |
| ISSN | 1471-230X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022. |
| File Version | publisher |
| PubMed ID | 35692036 |
| DOI | 10.1186/s12876-022-02368-w |
| Web of Science KeyUT | 000809663500001 |
| Related Url | isVersionOf https://doi.org/10.1186/s12876-022-02368-w |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Iwamuro, Masaya| Kawai, Yusuke| Uka, Mayu| Matsui, Yusuke| Hiraki, Takao| Kawahara, Yoshiro| Okada, Hiroyuki| |
| Published Date | 2022-04-07 |
| Publication Title | Case Reports In Gastrointestinal Medicine |
| Volume | volume2022 |
| Publisher | Hindawi Ltd. |
| Start Page | 9988216 |
| ISSN | 2090-6528 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 Masaya Iwamuro et al. |
| File Version | publisher |
| PubMed ID | 35433061 |
| DOI | 10.1155/2022/9988216 |
| Web of Science KeyUT | 000791234100001 |
| Related Url | isVersionOf https://doi.org/10.1155/2022/9988216 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Iwamuro, Masaya| Shiraha, Hidenori| Kobashi, Mayu| Horiguchi, Shigeru| Okada, Hiroyuki| |
| Keywords | cancer progression extracellular matrix gastric cancer cells laminin 511-E8 fragment laminin isoforms |
| Published Date | 2022-04-05 |
| Publication Title | Current Issues In Molecular Biology |
| Volume | volume44 |
| Issue | issue4 |
| Publisher | MDPI |
| Start Page | 1539 |
| End Page | 1551 |
| ISSN | 1467-3037 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| DOI | 10.3390/cimb44040105 |
| Web of Science KeyUT | 000785101600001 |
| Related Url | isVersionOf https://doi.org/10.3390/cimb44040105 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsueda, Katsunori| Kanzaki, Hiromitsu| Takenaka, Ryuta| Nakagawa, Masahiro| Matsueda, Kazuhiro| Iwamuro, Masaya| Kawano, Seiji| Kawahara, Yoshiro| Toji, Tomohiro| Tanaka, Takehiro| Yagi, Takahito| Fujiwara, Toshiyoshi| Okada, Hiroyuki| |
| Published Date | 2021-08-27 |
| Publication Title | PLOS ONE |
| Volume | volume16 |
| Issue | issue8 |
| Publisher | Public Library Science |
| Start Page | e0256797 |
| ISSN | 1932-6203 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Matsueda et al. |
| File Version | publisher |
| PubMed ID | 34449813 |
| DOI | 10.1371/journal.pone.0256797 |
| NAID | 120007193739 |
| Web of Science KeyUT | 000752313300044 |
| Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0256797 |
| Title Alternative | Four types of duodenal white lesions (follicular lymphoma, lymphoid hyperplasia, lymphangiectasia, and lymphangioma) : A case report |
|---|---|
| FullText URL | 133_175.pdf |
| Author | Iwamuro, Masaya| Tanaka, Takehiro| Okada, Hiroyuki| |
| Abstract | A 70-year-old Japanese man underwent esophagogastroduodenoscopy that revealed multiple whitish duodenal granules. The histopathological analysis of the biopsied specimen led to the diagnosis of duodenal-type follicular lymphoma. The lesion showed spontaneous improvement ; however, 14 months later a few small whitish granules were observed by esophagogastroduodenoscopy. Observation under magnification revealed slightly elevated opaque white spots and whitish granular protrusions of roughly the same size that were uniformly distributed in the duodenal bulb. The duodenal bulb lesions were histopathologically diagnosed as lymphoid hyperplasia. The patient also exhibited lymphangiectasia (which presented as scattered white spots) and lymphangioma (which presented as a soft submucosal tumor with white spots on the surface) in the second portion of the duodenum. This patient presented with four white lesions in the duodenum : duodenal-type follicular lymphoma, lymphoid hyperplasia, lymphangiectasia, and lymphangioma. Careful endoscopic evaluation enabled a prompt diagnosis in this case. |
| Keywords | 十二指腸濾胞性リンパ腫（duodenal-type follicular lymphoma） リンパ濾胞過形成（lymphoid hyperplasia） リンパ管腫（lymphangioma） リンパ管拡張（lymphangiectasia） |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2021-12-01 |
| Volume | volume133 |
| Issue | issue3 |
| Start Page | 175 |
| End Page | 180 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.133.175 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2021 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.133.175 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Iwamuro, Masaya| Takahashi, Takahide| Watanabe, Natsuki| Tanaka, Takehiro| Inokuchi, Toshihiro| Hiraoka, Sakiko| Otsuka, Fumio| Okada, Hiroyuki| |
| Keywords | central memory T cell flow cytometry natural killer T cells peripheral blood mononuclear cell ulcerative colitis |
| Published Date | 2022-01-12 |
| Publication Title | International Journal of Immunopathology and Pharmacology |
| Volume | volume36 |
| Publisher | Sage Publications Inc. |
| Start Page | 1 |
| End Page | 12 |
| ISSN | 0394-6320 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022 |
| File Version | publisher |
| PubMed ID | 35021918 |
| DOI | 10.1177/20587384211051982 |
| Web of Science KeyUT | 000747491200001 |
| Related Url | isVersionOf https://doi.org/10.1177/20587384211051982 |
