Carrier PNA for shRNA delivery into cells

ID	46938
FullText URL	BMCL_19_13_3410-3413.pdf 123 KB
Author	Kitamatsu, Mizuki Kaken ID publons researchmap Kubo, Takanori Matsuzaki, Rino Endoh, Tamaki Ohtsuki, Takashi ORCID Kaken ID publons researchmap Sisido, Masahiko
Abstract	A peptide nucleic acid (PNA)-cell-penetrating peptide (CPP) conjugate (carrier PNA) was used as 'bridgebuilder' to connect a CPP with an shRNA. The carrier PNA successfully formed a hybrid with an shRNA bearing complementary dangling bases and the shRNA was introduced into cells by the carrier PNA, and RNAi was induced by the shRNA.
Keywords	Peptide nucleic acid Cell-penetrating peptide RNA interference
Published Date	2009-07-01
Publication Title	Bioorganic & Medicinal Chemistry Letters
Volume	volume19
Issue	issue13
Publisher	Elsevier Ltd.
Start Page	3410
End Page	3413
ISSN	0960-894X
NCID	AA1079577X
Content Type	Journal Article
language	English
Copyright Holders	Crown Copyright © 2009 Published by Elsevier Ltd. All rights reserved.
File Version	author
Refereed	True
DOI	10.1016/j.bmcl.2009.05.031
PubMed ID	19481448
Web of Science KeyUT	000266822800010