FullText URL fulltext.pdf
Author Hasei, Joe| Nakahara, Ryuichi| Otsuka, Yujiro| Nakamura, Yusuke| Ikuta, Kunihiro| Osaki, Shuhei| Hironari, Tamiya| Miwa, Shinji| Ohshika, Shusa| Nishimura, Shunji| Kahara, Naoaki| Yoshida, Aki| Fujiwara, Tomohiro| Nakata, Eiji| Kunisada, Toshiyuki| Ozaki, Toshifumi|
Keywords osteosarcoma medical image annotation anatomical annotation method rare cancer
Published Date 2024-12-25
Publication Title Cancers
Volume volume17
Issue issue1
Publisher MDPI
Start Page 29
ISSN 2072-6694
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 39796660
DOI 10.3390/cancers17010029
Web of Science KeyUT 001393409100001
Related Url isVersionOf https://doi.org/10.3390/cancers17010029
FullText URL fulltext.pdf
Author Otani, Yusuke| Tanaka, Atsushi| Maekawa, Masaki| Peña, Tirso| Rogachevskaya, Anna| Ando, Teruhiko| Itano, Takuto| Katayama, Haruyoshi| Nakata, Eiji| Ozaki, Toshifumi| Toyooka, Shinichi| Doihara, Hiroyoshi| Roehrl, Michael H.| Fujimura, Atsushi|
Keywords C1orf50 Luminal A breast cancer Cell cycle Immune evasion YAP/TAZ
Note The version of record of this article, first published in Breast Cancer, is available online at Publisher’s website: http://dx.doi.org/10.1007/s12282-024-01653-8|
Published Date 2024-11-28
Publication Title Breast Cancer
Volume volume32
Issue issue2
Publisher Springer Science and Business Media LLC
Start Page 292
End Page 305
ISSN 1340-6868
NCID AA1103354X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 39604563
DOI 10.1007/s12282-024-01653-8
Web of Science KeyUT 001365140400001
Related Url isVersionOf https://doi.org/10.1007/s12282-024-01653-8
FullText URL fulltext.pdf
Author Futagawa, Mashu| Okazaki, Tetsuya| Nakata, Eiji| Fukano, Chika| Osumi, Risa| Kato, Fumino| Urakawa, Yusaku| Yamamoto, Hideki| Ozaki, Toshifumi| Hirasawa, Akira|
Note The version of record of this article, first published in Human Genome Variation, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41439-024-00299-4|
Published Date 2024-11-26
Publication Title Human Genome Variation
Volume volume11
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 42
ISSN 2054-345X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 39592598
DOI 10.1038/s41439-024-00299-4
Web of Science KeyUT 001363412200001
Related Url isVersionOf https://doi.org/10.1038/s41439-024-00299-4
FullText URL fulltext.pdf
Author Furumatsu, Takayuki| Kintaka, Keisuke| Higashihara, Naohiro| Tamura, Masanori| Kawada, Koki| Xue, Haowei| Ozaki, Toshifumi|
Keywords Medial meniscus Posterior root Partial tear Meniscal extrusion Operative indication
Note The version of record of this article, first published in Knee Surgery & Related Research, is available online at Publisher’s website: http://dx.doi.org/10.1186/s43019-023-00182-6|
Published Date 2023-03-14
Publication Title Knee Surgery & Related Research
Volume volume35
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 8
ISSN 2234-2451
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023.
File Version publisher
PubMed ID 36918982
DOI 10.1186/s43019-023-00182-6
Web of Science KeyUT 000949319200001
Related Url isVersionOf https://doi.org/10.1186/s43019-023-00182-6
JaLCDOI 10.18926/AMO/67655
FullText URL 78_5_357.pdf
Author Yamawaki, Ryoko| Oda, Yoshiaki| Yamane, Shuhei| Uotani, Koji| Misawa, Haruo| Katayama, Yoshimi| Hamada, Masanori| Ozaki, Toshifumi|
Abstract Research on postural control in patients with adolescent idiopathic scoliosis (AIS) has focused on static postural control, with few studies assessing dynamic postural control. We aimed to identify factors affecting index of postural stability (IPS), a dynamic postural control parameter, in patients with AIS. The participants comprised 50 female patients with AIS. We measured the IPS using stabilometry to evaluate dynamic postural control ability. We investigated age of the participants, major curve position (thoracic or thoracolumbar/lumbar), Cobb angle, and coronal balance. We then assessed the relationships between stabilometry parameters and other variables. IPS was analyzed with a linear regression model. Coronal balance, major curve position, and age each correlated with dynamic postural control ability. The Cobb angle showed no correlation with any of the parameters. Our results offer new insights into the assessment of postural control in patients with AIS.
Keywords adolescent idiopathic scoliosis postural control coronal balance index of postural stability stabilometry
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-10
Volume volume78
Issue issue5
Publisher Okayama University Medical School
Start Page 357
End Page 362
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 39467653
Web of Science KeyUT 001343346400001
FullText URL fulltext.pdf
Author Uotani, Koji| Fujiwara, Tomohiro| Ueda, Koji| Yoshida, Aki| Iwata, Shintaro| Morita, Takuya| Kiyono, Masahiro| Kunisada, Toshiyuki| Takeda, Ken| Hasei, Joe| Yoshioka, Yusuke| Ochiya, Takahiro| Ozaki, Toshifumi|
Keywords circulating biomarker Ewing sarcoma extracellular vesicles liquid biopsy proteome
Published Date 2024-09-22
Publication Title Cancer Science
Volume volume115
Issue issue11
Publisher Wiley
Start Page 3660
End Page 3671
ISSN 1347-9032
NCID AA11808050
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Author(s).
File Version publisher
PubMed ID 39307979
DOI 10.1111/cas.16343
Web of Science KeyUT 001318444100001
Related Url isVersionOf https://doi.org/10.1111/cas.16343
FullText URL fulltext.pdf
Author Hasei, Joe| Nakahara, Ryuichi| Otsuka, Yujiro| Nakamura, Yusuke| Hironari, Tamiya| Kahara, Naoaki| Miwa, Shinji| Ohshika, Shusa| Nishimura, Shunji| Ikuta, Kunihiro| Osaki, Shuhei| Yoshida, Aki| Fujiwara, Tomohiro| Nakata, Eiji| Kunisada, Toshiyuki| Ozaki, Toshifumi|
Keywords artificial intelligence clinical decision support diagnostic imaging image annotation osteosarcoma detection
Published Date 2024-09-02
Publication Title Cancer Science
Volume volume115
Issue issue11
Publisher Wiley
Start Page 3695
End Page 3704
ISSN 1347-9032
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Author(s).
File Version publisher
PubMed ID 39223070
DOI 10.1111/cas.16330
Web of Science KeyUT 001302420900001
Related Url isVersionOf https://doi.org/10.1111/cas.16330
FullText URL fulltext.pdf
Author Ueda, Masataka| Tetsunaga, Tomoko| Tetsunaga, Tomonori| Nishida, Keiichiro| Takatori, Ryo| Shitozawa, Hisakazu| Uotani, Koji| Shinohara, Kennsuke| Oda, Yoshiaki| Ozaki, Toshifumi|
Keywords AIS cognitive-behavioral therapy EQ5D HADS insomnia pain-liaison outpatient clinic sleep disorders
Published Date 2024-08-09
Publication Title Medicine
Volume volume103
Issue issue32
Publisher Lippincott, Williams & Wilkins
Start Page e39113
ISSN 0025-7974
NCID AA00728867
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 the Author(s).
File Version publisher
PubMed ID 39121265
DOI 10.1097/MD.0000000000039113
Web of Science KeyUT 001287977800045
Related Url isVersionOf https://doi.org/10.1097/MD.0000000000039113
FullText URL fulltext.pdf
Author Hasei, Joe| Ishida, Hisashi| Katayama, Hideki| Maeda, Naoko| Nagano, Akihito| Ochi, Motoharu| Okamura, Masako| Iwata, Shintaro| Ikuta, Kunihiro| Yoshida, Shinichirou| Fujiwara, Tomohiro| Nakata, Eiji| Nakahara, Ryuichi| Kunisada, Toshiyuki| Ozaki, Toshifumi|
Keywords virtual reality metaverse adolescent and young adult rare cancer mental health
Published Date 2024-07-23
Publication Title Cancers
Volume volume16
Issue issue15
Publisher MDPI
Start Page 2617
ISSN 2072-6694
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 39123345
DOI 10.3390/cancers16152617
Web of Science KeyUT 001287028100001
Related Url isVersionOf https://doi.org/10.3390/cancers16152617
FullText URL fulltext.pdf
Author Kunisada, Toshiyuki| Nakata, Eiji| Fujiwara, Tomohiro| Hata, Toshiaki| Sato, Kohei| Katayama, Haruyoshi| Kondo, Ayana| Ozaki, Toshifumi|
Keywords hydroxyapatite bone tumor orthopedic surgery unidirectional porous hydroxyapatite bone graft
Published Date 2024-05-15
Publication Title Biomimetics
Volume volume9
Issue issue5
Publisher MDPI
Start Page 294
ISSN 2313-7673
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 38786504
DOI 10.3390/biomimetics9050294
Web of Science KeyUT 001232206900001
Related Url isVersionOf https://doi.org/10.3390/biomimetics9050294
FullText URL fulltext.pdf
Author Nakata, Eiji| Sugihara, Shinsuke| Nakahara, Ryuichi| Katayama, Haruyoshi| Itano, Takuto| Ozaki, Toshifumi|
Keywords spinal metastases spinal instability neoplastic score radiotherapy posterolateral involvement of spinal elements risk factor
Published Date 2024-04-30
Publication Title Cancer Control
Volume volume31
Publisher SAGE Publications
ISSN 1073-2748
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 38686892
DOI 10.1177/10732748241250219
Web of Science KeyUT 001210831600001
Related Url isVersionOf https://doi.org/10.1177/10732748241250219
FullText URL fulltext.pdf
Author Uotani, Koji| Tazawa, Hiroshi| Hasei, Joe| Fujiwara, Tomohiro| Yoshida, Aki| Yamakawa, Yasuaki| Omori, Toshinori| Sugiu, Kazuhisa| Komatsubara, Tadashi| Kondo, Hiroya| Morita, Takuya| Kiyono, Masahiro| Yokoo, Suguru| Hata, Toshiaki| Kunisada, Toshiyuki| Takeda, Ken| Urata, Yasuo| Fujiwara, Toshiyoshi| Ozaki, Toshifumi|
Published Date 2024-02-20
Publication Title PLoS ONE
Volume volume19
Issue issue2
Publisher Public Library of Science
Start Page e0298292
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Uotani et al.
File Version publisher
PubMed ID 38377118
DOI 10.1371/journal.pone.0298292
Web of Science KeyUT 001176939600021
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0298292
JaLCDOI 10.18926/AMO/66924
FullText URL 78_2_151.pdf
Author Komatsubara, Tadashi| Tazawa, Hiroshi| Hasei, Joe| Omori, Toshinori| Sugiu, Kazuhisa| Mochizuki, Yusuke| Demiya, Koji| Yoshida, Aki| Fujiwara, Tomohiro| Kunisada, Toshiyuki| Urata, Yasuo| Kagawa, Shunsuke| Ozaki, Toshifumi| Fujiwara, Toshiyoshi|
Abstract Soft-tissue sarcoma (STS) is a heterogeneous group of rare tumors originating predominantly from the embryonic mesoderm. Despite the development of combined modalities including radiotherapy, STSs are often refractory to antitumor modalities, and novel strategies that improve the prognosis of STS patients are needed. We previously demonstrated the therapeutic potential of two telomerase-specific replication-competent oncolytic adenoviruses, OBP-301 and tumor suppressor p53-armed OBP-702, in human STS cells. Here, we demonstrate in vitro and in vivo antitumor effects of OBP-702 in combination with ionizing radiation against human STS cells (HT1080, NMS-2, SYO-1). OBP-702 synergistically promoted the antitumor effect of ionizing radiation in the STS cells by suppressing the expression of B-cell lymphoma-X large (BCL-xL) and enhancing ionizing radiation-induced apoptosis. The in vivo experiments demonstrated that this combination therapy significantly suppressed STS tumors’ growth. Our results suggest that OBP-702 is a promising antitumor reagent for promoting the radiosensitivity of STS tumors.
Keywords soft-tissue sarcoma radiotherapy oncolytic adenovirus p53 BCL-xL
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 151
End Page 161
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688833
Web of Science KeyUT 001229151800007
FullText URL fulltext.pdf
Author Fujiwara, Tomohiro| Kunisada, Toshiyuki| Nakata, Eiji| Nishida, Kenji| Yanai, Hiroyuki| Nakamura, Tomoki| Tanaka, Kazuhiro| Ozaki, Toshifumi|
Keywords alveolar soft part sarcoma surgery chemotherapy targeted therapy immunotherapy
Published Date 2023-08-25
Publication Title Japanese Journal of Clinical Oncology
Volume volume53
Issue issue11
Publisher Oxford University Press (OUP)
Start Page 1009
End Page 1018
ISSN 1465-3621
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023.
File Version publisher
PubMed ID 37626447
DOI 10.1093/jjco/hyad102
Web of Science KeyUT 001080372000001
Related Url isVersionOf https://doi.org/10.1093/jjco/hyad102
FullText URL fulltext.pdf
Author Nakamichi, Ryo| Saito, Taichi| Shimamura, Yasunori| Hamada, Masanori| Nishida, Keiichiro| Ozaki, Toshifumi|
Keywords Carpal tunnel syndrome Mini-open Endoscopy Patient-oriented evaluation
Note The version of record of this article, first published in BMC Musculoskeletal Disorders, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12891-023-07151-w|
Published Date 2024-04-01
Publication Title BMC Musculoskeletal Disorders
Volume volume25
Issue issue1
Publisher BMC
Start Page 251
ISSN 1471-2474
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024.
File Version publisher
PubMed ID 38561698
DOI 10.1186/s12891-023-07151-w
Web of Science KeyUT 001195650000009
Related Url isVersionOf https://doi.org/10.1186/s12891-023-07151-w
FullText URL fulltext.pdf
Author Takihira, Shota| Yamada, Daisuke| Osone, Tatsunori| Takao, Tomoka| Sakaguchi, Masakiyo| Hakozaki, Michiyuki| Itano, Takuto| Nakata, Eiji| Fujiwara, Tomohiro| Kunisada, Toshiyuki| Ozaki, Toshifumi| Takarada, Takeshi|
Note The version of record of this article, first published in British Journal of Cancer, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41416-024-02632-8|
Published Date 2024-03-06
Publication Title British Journal of Cancer
Volume volume130
Issue issue9
Publisher Springer Science and Business Media LLC
Start Page 1493
End Page 1504
ISSN 0007-0920
NCID AA00574355
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 38448751
DOI 10.1038/s41416-024-02632-8
Web of Science KeyUT 001180796100003
Related Url isVersionOf https://doi.org/10.1038/s41416-024-02632-8
FullText URL fulltext.pdf
Author Hotta, Yoshifumi| Nishida, Keiichiro| Yoshida, Aki| Nasu, Yoshihisa| Nakahara, Ryuichi| Naniwa, Shuichi| Shimizu, Noriyuki| Ichikawa, Chinatsu| Lin, Deting| Fujiwara, Tomohiro| Ozaki, Toshifumi|
Keywords osteoarthritis chondrocyte mechanical stress tankyrases XAV939 SOX9 ADAMTS-5 MMP-13 IL-1β NF-κB β-catenin
Published Date 2024-01-24
Publication Title International Journal of Molecular Sciences
Volume volume25
Issue issue3
Publisher MDPI
Start Page 1443
ISSN 1661-6596
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 38338721
DOI 10.3390/ijms25031443
Web of Science KeyUT 001161430700001
Related Url isVersionOf https://doi.org/10.3390/ijms25031443
JaLCDOI 10.18926/AMO/66673
FullText URL 78_1_071.pdf
Author Kaneda, Daisuke| Nishida, Keiichiro| Nasu, Yoshihisa| Nakahara, Ryuichi| Harada, Ryozo| Hotta, Yoshifumi| Naniwa, Shuichi| Ozaki, Toshifumi|
Abstract We retrospectively investigated the mid-term outcomes of arthroplasty using the AVANTA silicone implant for thumb metacarpophalangeal (MCP) joints with boutonniere deformity in patients with rheumatoid arthritis (RA). This study involved 36 thumbs of 33 RA patients with a mean follow-up period of 5.1 years (range, 2.0-13.3). Postoperatively, the mean extension was significantly increased and the mean flexion was significantly decreased (p<0.001, p<0.001, respectively), resulting in the mean arc of range of motion (ROM) shifting in the direction of extension after surgery. Implant fracture was observed in 10 thumbs (28%), and 4 of these (11%) underwent revision surgery. The survivorship with implant fracture and revision surgery as endpoints were 73.4% and 91.8% at 5 years, respectively. The preoperative arc of ROM and the postoperative flexion range of the implant-fracture group were significantly greater than those in the no-implant-fracture group (p=0.039, 0.034, respectively). These results suggest the importance of patient education and careful rehabilitation to prevent excessive flexion. Overall, the AVANTA silicone implant showed a relatively high rate of implant fracture at our institute.
Keywords AVANTA silicone implant boutonniere deformity implant fracture thumb metacarpophalangeal joint arthroplasty rheumatoid arthritis
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-02
Volume volume78
Issue issue1
Publisher Okayama University Medical School
Start Page 71
End Page 78
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38419317
Web of Science KeyUT 001203658200011
JaLCDOI 10.18926/AMO/66667
FullText URL 78_1_021.pdf
Author Tamura, Masanori| Furumatsu, Takayuki| Yokoyama, Yusuke| Kintaka, Keisuke| Higashihara, Naohiro| Kawada, Koki| Ozaki, Toshifumi|
Abstract The use of various strategies for arthroscopic meniscal repairs to save the meniscus and prevent the progression of knee osteoarthritis has gradually increased. We investigated the frequency of various arthroscopic treatments and the short-term clinical outcomes of symptomatic isolated medial meniscus (MM) injuries. This retrospective observational study included 193 patients (197 knees) who underwent arthroscopic meniscal treatment for isolated MM injuries between January 2016 and April 2019. Arthroscopic meniscal repairs were divided into two groups: transtibial pullout repairs of MM posterior root tears (MMPRTs) and arthroscopic meniscal repairs for other types of MM injuries. MMPRT pullout repair, other meniscal repairs, and partial meniscectomy were performed in 71.0%, 16.8%, and 12.2% of the knees, respectively. The ratio of women to men and the patient age were higher in the pullout-repair group than the meniscal-repair group. The Preoperative Knee Injury and Osteoarthritis Outcome Score subscale (as an index of daily living activities) was significantly lower in the pullout-repair group than the meniscus-repair group. However, no significant differences were observed in these scores among the two groups postoperatively. Our results suggest that familiarity with the diagnosis and treatment of MMPRTs is necessary for orthopedic surgeons to manage isolated MM injuries.
Keywords knee medial meniscus posterior root tear arthroscopy pullout repair
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-02
Volume volume78
Issue issue1
Publisher Okayama University Medical School
Start Page 21
End Page 27
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38419311
Web of Science KeyUT 001203658200002
FullText URL fulltext.pdf
Author Tamura, Masanori| Furumatsu, Takayuki| Yokoyama, Yusuke| Higashihara, Naohiro| Kawada, Koki| Ozaki, Toshifumi|
Keywords Knee injuries Arthroscopy Meniscus Root tear
Note The version of record of this article, first published in Knee Surgery & Related Research, is available online at Publisher’s website: http://dx.doi.org/10.1186/s43019-023-00206-1|
Published Date 2024-02-08
Publication Title Knee Surgery & Related Research
Volume volume36
Issue issue1
Publisher Springer Nature
Start Page 8
ISSN 2234-2451
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024.
File Version publisher
PubMed ID 38331953
DOI 10.1186/s43019-023-00206-1
Web of Science KeyUT 001160637100001
Related Url isVersionOf https://doi.org/10.1186/s43019-023-00206-1