| ID | 17575 |
| Eprint ID | 17575
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| FullText URL | |
| Title Alternative | Studies on the induction and development of Iymphosarcoma by N-Nitrosobutylurea in RF Mice. Ⅰ. Histological and cytological observations
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| Author |
Tanzi, Tameyo
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| Abstract | In order to study the carcinogenicity and its mechanism of N-Nitrosobutylurea (NBU), 10 week old RF mice was abministrated with 0.025% NBU water solution as drinking water every day. 1. Thymoma was induced after an average latency of 93 days and average rate of the tumor induction was 88.6%. Both sexes were equally susceptible. 2. Histologically thymoma was lymphosarcoma and other lymphatic organs also showed lymphosarcoma. However leukemic signs were not found in the peripheral blood and by clinical tissue culture. 3. Leukemia virus was not found in the electron microscpic observation and cell free transmission of leukemia was unsuccessfull.
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| Published Date | 1973-08-30
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| Publication Title |
岡山医学会雑誌
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| Publication Title Alternative | Journal of Okayama Medical Association
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| Volume | volume85
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| Issue | issue7-8
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| Publisher | 岡山医学会
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| Publisher Alternative | Okayama Medical Association
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| Start Page | 249
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| End Page | 264
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| ISSN | 0030-1558
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| NCID | AN00032489
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| Content Type |
Journal Article
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| Official Url | https://www.jstage.jst.go.jp/article/joma1947/85/7-8/85_7-8_249/_article/-char/ja/
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| Related Url | http://www.okayama-u.ac.jp/user/oma/
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| language |
Japanese
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| Copyright Holders | 岡山医学会
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| File Version | publisher
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| Refereed |
True
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| Eprints Journal Name | joma
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