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ID 62781
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Author
Ino, Riku Department of Internal Medicine, Kochi Prefectural Hata-Kenmin Hospital
Sada, Ken-ei Department of Internal Medicine, Kochi Prefectural Hata-Kenmin Hospital
Miyauchi, Atsushi Department of Internal Medicine, Kochi Prefectural Hata-Kenmin Hospital
Hashimoto, Daisuke Department of Internal Medicine, Kochi Prefectural Hata-Kenmin Hospital
Nojima, Shigeru Department of Internal Medicine, Kochi Prefectural Hata-Kenmin Hospital
Yamanaka, Shingo Department of Internal Medicine, Kochi Prefectural Hata-Kenmin Hospital
Kawamura, Masafumi Department of Internal Medicine, Kochi Prefectural Hata-Kenmin Hospital
Abstract
A 77-year-old woman with no history of malignancy presented with anorexia and bilateral lower extremity weakness. Her consciousness level worsened daily, so we performed a lumbar puncture. Cerebrospinal fluid (CSF) analysis indicated meningitis, but three rounds of CSF cytology showed no malignant cells. The patient’s carcinoembryonic antigen (CEA) level was highly elevated in CSF, but normal in serum. Through gadolinium-enhanced brain/spinal magnetic resonance imaging and gastrointestinal endoscopy, she was diagnosed with leptomeningeal carcinomatosis (LC) from gastric cancer. CEA level in CSF facilitated the diagnosis of LC from gastric cancer because there were no malignant cells on CSF cytology.
Keywords
leptomeningeal carcinomatosis
gastric cancer
carcinoembryonic antigen
cerebrospinal fluid cytology
Amo Type
Case Report
Publication Title
Acta Medica Okayama
Published Date
2021-10
Volume
volume75
Issue
issue5
Publisher
Okayama University Medical School
Start Page
659
End Page
661
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
English
Copyright Holders
CopyrightⒸ 2021 by Okayama University Medical School
File Version
publisher
Refereed
True
PubMed ID
Web of Science KeyUT
NAID