尾崎敏文

Transtibial fixation for medial meniscus posterior root tear reduces posterior extrusion and physiological translation of the medial meniscus in middle-aged and elderly patients

フルテキストURL	fulltext.pdf Figure.pptx Tables.pptx
著者	Kodama, Yuya\| Furumatsu, Takayuki\| Masuda, Shin\| Okazaki, Yoshiki\| Kamatsuki, Yusuke\| Okazaki, Yuki\| Hiranaka, Takaaki\| Miyazawa, Shinichi\| Yasumitsu, Masaharu\| Ozaki, Toshifumi\|
キーワード	Medial meniscus Posterior root tear Transtibial fixation Meniscus extrusion Open magnetic resonance imaging
備考	This is a post-peer-review, pre-copyedit version of an article published in Knee Surgery, Sports Traumatology, Arthroscopy. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00167-019-05810-x.</br>\|
発行日	2019-11-28
出版物タイトル	Knee Surgery, Sports Traumatology, Arthroscopy
巻	28巻
号	11号
出版者	Springer
開始ページ	3416
終了ページ	3425
ISSN	0942-2056
NCID	AA10973641
資料タイプ	学術雑誌論文
言語	English
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	31781798
DOI	10.1007/s00167-019-05810-x
Web of Science KeyUT	000575537100001
関連URL	isVersionOf https://doi.org/10.1007/s00167-019-05810-x

Telomerase-specific oncolytic immunotherapy for promoting efficacy of PD-1 blockade in osteosarcoma

著者	Mochizuki, Yusuke\| Tazawa, Hiroshi\| Demiya, Koji\| Kure, Miho\| Kondo, Hiroya\| Komatsubara, Tadashi\| Sugiu, Kazuhisa\| Hasei, Joe\| Yoshida, Aki\| Kunisada, Toshiyuki\| Urata, Yasuo\| Kagawa, Shunsuke\| Ozaki, Toshifumi\| Fujiwara, Toshiyoshi\|
キーワード	Oncolytic adenovirus hTERT Immunogenic cell death ATP CD8
備考	This is a post-peer-review, pre-copyedit version of an article published in Cancer Immunology, Immunotherapy. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00262-020-02774-7. </br>This fulltext is available in Nov. 2021.\|
発行日	2020-11-05
出版物タイトル	Cancer Immunology, Immunotherapy
出版者	Springer
開始ページ	0340-7004
NCID	AA00598499
資料タイプ	学術雑誌論文
言語	English
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	33151368
DOI	10.1007/s00262-020-02774-7
Web of Science KeyUT	000586350500002
関連URL	isVersionOf https://doi.org/10.1007/s00262-020-02774-7

Transtibial pullout repair of medial meniscus posterior root tears: effects on the meniscus healing score and ICRS grade among patients with mild osteoarthritis of the knee

著者	Kodama, Yuya\| Furumatsu, Takayuki\| Okazaki, Yuki\| Takihira, Shota\| Hiranaka, Takaaki\| Miyazawa, Shinichi\| Kamatsuki, Yusuke\| Ozaki, Toshifumi\|
キーワード	Medial meniscus Posterior root tear Transtibial pullout repair Meniscal healing Cartilage degeneration
備考	This is a post-peer-review, pre-copyedit version of an article published in Knee Surgery, Sports Traumatology, Arthroscopy. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00167-020-06332-7. <br>This fulltext is available in Oct. 2021.\|
発行日	2020-08-28
出版物タイトル	Knee Surgery, Sports Traumatology, Arthroscopy
出版者	Springer
ISSN	0942-2056
NCID	AA10973641
資料タイプ	学術雑誌論文
言語	English
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	33112966
DOI	10.1007/s00167-020-06332-7
Web of Science KeyUT	000584906000002
関連URL	isVersionOf https://doi.org/10.1007/s00167-020-06332-7

Medial meniscus posterior root tear causes swelling of the medial meniscus and expansion of the extruded meniscus: a comparative analysis between 2D and 3D MRI

フルテキストURL	fulltext.pdf
著者	Okazaki, Yoshiki\| Furumatsu, Takayuki\| Yamaguchi, Takuya\| Kodama, Yuya\| Kamatsuki, Yusuke\| Masuda, Shin\| Okazaki, Yuki\| Hiranaka, Takaaki\| Zhang, Ximing\| Ozaki, Toshifumi\|
キーワード	Medial meniscus Posterior root tear Osteoarthritis Meniscal volume Medial extrusion Three-dimensional magnetic resonance imaging Flexed-knee position
備考	This is a post-peer-review, pre-copyedit version of an article published in Knee Surgery, Sports Traumatology, Arthroscopy. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00167-019-05580-6.\|
発行日	2019-06-26
出版物タイトル	Knee Surgery, Sports Traumatology, Arthroscopy
巻	28巻
号	11号
出版者	Springer
開始ページ	3405
終了ページ	3415
ISSN	0942-2056
NCID	AA10973641
資料タイプ	学術雑誌論文
言語	English
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	31243505
DOI	10.1007/s00167-019-05580-6
Web of Science KeyUT	000584542500002
関連URL	isVersionOf https://doi.org/10.1007/s00167-019-05580-6

Multipotent Neurotrophic Effects of Hepatocyte Growth Factor in Spinal Cord Injury

フルテキストURL	fulltext.pdf
著者	Yamane, Kentaro\| Misawa, Haruo\| Takigawa, Tomoyuki\| Ito, Yoshihiro\| Ozaki, Toshifumi\| Matsukawa, Akihiro\|
キーワード	hepatocyte growth factor spinal cord injury neural regeneration
発行日	2019-12-02
出版物タイトル	International Journal of Molecular Sciences
巻	20巻
号	23号
出版者	MDPI
開始ページ	6078
ISSN	1422-0067
資料タイプ	学術雑誌論文
言語	English
OAI-PMH Set	岡山大学
著作権者	© 2019 by the authors.
論文のバージョン	publisher
PubMed ID	31810304
DOI	10.3390/ijms20236078
Web of Science KeyUT	000504428300260
関連URL	isVersionOf https://doi.org/10.3390/ijms20236078

A novel, visible light-induced, rapidly cross-linkable gelatin scaffold for osteochondral tissue engineering

著者	Mazaki, Tetsuro\| Shiozaki, Yasuyuki\| Yamane, Kentaro\| Yoshida, Aki\| Nakamura, Mariko\| Yoshida, Yasuhiro\| Zhou, Di\| Kitajima, Takashi\| Tanaka, Masato\| Ito, Yoshihiro\| Ozaki, Toshifumi\| Matsukawa, Akihiro\|
発行日	2014-03-25
出版物タイトル	Scientific Reports
巻	4巻
資料タイプ	学術雑誌論文

Enhanced in vivo osteogenesis by nanocarrier-fused bone morphogenetic protein-4

著者	Shiozaki, Yasuyuki\| Kitajima, Takashi\| Mazaki, Tetsuro\| Yoshida, Aki\| Tanaka, Masato\| Umezawa, Akihiro\| Nakamura, Mariko\| Yoshida, Yasuhiro\| Ito, Yoshihiro\| Ozaki, Toshifumi\| Matsukawa, Akihiro\|
発行日	2013-04
出版物タイトル	International Journal of Nanomedicine
巻	8巻
号	1号
資料タイプ	学術雑誌論文

Occult Compression Fracture of Metacarpal Head without Evidence of Avascular Necrosis

JaLCDOI	10.18926/AMO/51867
フルテキストURL	67_5_311.pdf
著者	Nishida, Keiichiro\| Hashizume, Hiroyuki\| Matsukawa, Akihiro\| Hashizume, Kenzo\| Shimamura, Yasunori\| Torigoe, Yasuyuki\| Ozaki, Toshifumi\|
抄録	We report a case of 4th metacarpal head collapse of a 19-year-old healthy man. MRI revealed T1 low and T2 high regions in the collapsed 4th metacarpal head, as well as in the right 3rd and left 4th metacarpal head. Our initial diagnosis was occult compression fracture due to avascular necrosis, known as Dieterich's disease. However, pathological findings of surgically resected right 4th metacarpal head were compatible with transient osteoporosis and metacarpal head fracture followed by active tissue repair. The autologous osteochondral transplants from costchondral junction survived and maintained their size and shape even at 10-year follow-up.
キーワード	occult compression fracture metacarpal head avascular necrosis osteochondral autograft
Amo Type	Case Report
発行日	2013-10
出版物タイトル	Acta Medica Okayama
巻	67巻
号	5号
出版者	Okayama University Medical School
開始ページ	311
終了ページ	317
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	English
著作権者	CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	24145731
Web of Science KeyUT	000325836100005

Significant growth suppression of synovial sarcomas by the histone deacetylase inhibitor FK228 in vitro and in vivo

著者	Ito, Tatsuo\| Ouchida, Mamoru\| Morimoto, Yuki\| Yoshida, Aki\| Jitsumori, Yoshimi\| Ozaki, Toshifumi\| Sonobe, Hiroshi\| Inoue, Hajime\| Shimizu, Kenji\|
発行日	2005-06-28
出版物タイトル	Cancer Letters
巻	224巻
号	2号
資料タイプ	学術雑誌論文

Short-term outcomes of mirogabalin in patients with peripheral neuropathic pain: a retrospective study

フルテキストURL	fulltext.pdf
著者	Tetsunaga, Tomoko\| Tetsunaga, Tomonori\| Nishida, Keiichiro\| Misawa, Haruo\| Takigawa, Tomoyuki\| Yamane, Kentaro\| Tsuji, Hironori\| Takei, Yoshitaka\| Ozaki, Toshifumi\|
キーワード	Peripheral neuropathic pain Mirogabalin Pregabalin Adverse event
発行日	2020-05-26
出版物タイトル	Journal of Orthopaedic Surgery and Research
巻	15巻
号	1号
出版者	Springer
開始ページ	191
ISSN	1749-799X
資料タイプ	学術雑誌論文
言語	English
OAI-PMH Set	岡山大学
論文のバージョン	publisher
PubMed ID	32456647
DOI	10.1186/s13018-020-01709-3
Web of Science KeyUT	000538017400002
関連URL	isVersionOf https://doi.org/10.1186/s13018-020-01709-3

An accelerometer-based navigation system provides acetabular cup orientation accuracy comparable to that of computed tomography-based navigation during total hip arthroplasty in the supine position

フルテキストURL	fulltext.pdf
著者	Tetsunaga, Tomonori\| Yamada, Kazuki\| Tetsunaga, Tomoko\| Sanki, Tomoaki\| Kawamura, Yoshi\| Ozaki, Toshifumi\|
キーワード	Hip Navigation system Total hip replacement Retrospective study
発行日	2020-04-15
出版物タイトル	Journal of Orthopaedic Surgery and Research
巻	15巻
号	1号
出版者	BMC
開始ページ	147
ISSN	1749-799X
資料タイプ	学術雑誌論文
言語	English
OAI-PMH Set	岡山大学
PubMed ID	32295628
Web of Science KeyUT	000528950200002
関連URL	isVersionOf https://doi.org/10.1186/s13018-020-01673-y

Medial meniscus posterior root repair decreases posteromedial extrusion of the medial meniscus during knee flexion

著者	Okazaki, Yuki\| Furumatsu, Takayuki\| Okazaki, Yoshiki\| Masuda, Shin\| Hiranaka, Takaaki\| Kodama, Yuya\| Kamatsuki, Yusuke\| Miyazawa, Shinichi\| Tetsunaga, Tomonori\| Ozaki, Toshifumi\|
キーワード	Magnetic resonance imaging Medial meniscus Meniscus extrusion Posterior root tear Three-dimensional assessment
備考	This fulltext is available in Feb. 2021.\|
発行日	2020-01-01
出版物タイトル	The Knee
巻	27巻
号	1号
出版者	Elsevier
開始ページ	132
終了ページ	139
ISSN	09680160
NCID	AA10996272
資料タイプ	学術雑誌論文
言語	English
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	31882388
DOI	10.1016/j.knee.2019.09.005
Web of Science KeyUT	000519666300017
関連URL	isVersionOf https://doi.org/10.1016/j.knee.2019.09.005

Idiopathic Chondrolysis of the Hip Treated by Immunosuppressive Therapy and Arthroscopic Intervention

JaLCDOI	10.18926/AMO/57957
フルテキストURL	74_1_77.pdf
著者	Endo, Hirosuke\| Akazawa, Hirofumi\| Yashiro, Masato\| Yamada, Kazuki\| Sanki, Tomoaki\| Tetsunaga, Tomonori\| Nishida, Keiichiro\| Furumatsu, Takayuki\| Ozaki, Toshifumi\|
抄録	Idiopathic chondrolysis of the hip (ICH), a very rare disorder of unknown etiology, occurs mainly in female adolescents. Characterized by pain, limp, stiffness and radiological narrowing joint space from the rapid destruction of the articular cartilage, ICH sometimes results in ankyloses. We present the case of a 10-year-old girl diagnosed with ICH based on arthroscopic inspection and synovium biopsy. The femoral deformity appeared gradually, like a cam-type femoroacetabular impingement. She was treated with intensive rehabilitation and immunosuppressive drug. We later performed an arthroscopic bumpectomy for residual symptoms. She achieved a favorable outcome as a 15-year-old at the latest follow-up.
キーワード	idiopathic chondrolysis hip joint medication bump arthroscopy
Amo Type	Case Report
発行日	2020-02
出版物タイトル	Acta Medica Okayama
巻	74巻
号	1号
出版者	Okayama University Medical School
開始ページ	77
終了ページ	81
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	English
著作権者	CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	32099253
Web of Science KeyUT	000516606200012
NAID	120006795624

Ten-Year Outcomes of Total Hip Arthroplasty Using Fit-and-Fill Type Cementless Collared Straight Stem Implants: Relationship between the Initial Contact Status and Stress Shielding

JaLCDOI	10.18926/AMO/57947
フルテキストURL	74_1_7.pdf
著者	Sanki, Tomoaki\| Endo, Hirosuke\| Tetsunaga, Tomonori\| Furumatsu, Takayuki\| Yamada, Kazuki\| Ozaki, Toshifumi\|
抄録	We investigated the relationship between the initial contact status and stress shielding in total hip arthroplasty (THA) using fit-and-fill type straight-stem implants. In addition we evaluated the clinical and radiographic outcomes. Subjects were 100 hips of 94 patients who underwent THA and were followed-up for ≥10 years. Contact areas with the femoral cortical bone were investigated according to the zonal distribution of Gruen using postoperative CT images. Depending on the number of contact areas, the patients were classified into high contact [HC], medium contact [MC], and low contact [LC] groups. Radiographic and clinical outcomes were evaluated. In the HC group (20 hips), severe stress shielding was observed in 12 hips, which was statistically significant (p=0.008). In the LC group (29 hips), mild stress shielding was observed in 27 hips which was statistically significant (p<0.001). No significant differences were observed among the 3 groups in clinical outcomes, Harris hip score (p=0.719) or Japanese Orthopedic Association (JOA) score (p=0.301). In insertion of cementless collared fit-and-fill type straight-stem implants, severe late stress shielding of the femoral bone may occur if high contact of the femoral component is achieved. However, the degree of stress shielding does not result in adverse clinical outcomes.
キーワード	fit-and-fill stress shielding cementless straight stem total hip arthroplasty
Amo Type	Original Article
発行日	2020-02
出版物タイトル	Acta Medica Okayama
巻	74巻
号	1号
出版者	Okayama University Medical School
開始ページ	7
終了ページ	15
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	English
著作権者	CopyrightⒸ 2020 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	32099243
Web of Science KeyUT	000516606200002
NAID	120006795614

Very rare solitary primary peripheral nerve onset cytotoxic molecule-positive peripheral T-cell lymphoma (PTCL)

フルテキストURL	NCN7_3_146.pdf Fig.pdf
著者	Matsumoto, Namiko\| Sato, Kota\| Takahashi, Yoshiaki\| Kawahara, Yuko\| Yunoki, Taijun\| Shang, Jingwei\| Takemoto, Mami\| Hishikawa, Nozomi\| Ohta, Yasuyuki\| Yamashita, Toru\| Sakamoto, Maiko\| Kondou, Eisei\| Shibata, Rei\| Yoshino, Tadashi\| Ozaki, Toshifumi\| Abe, Koji\|
キーワード	neurolymphomatosis neuro-oncology peripheral neuropathy peripheral nerve rheumatoid arthritis T-cell lymphoma
備考	This fulltext will be available in Feb 2020\|
発行日	2019-02-19
出版物タイトル	Neurology and Clinical Neuroscience
巻	7巻
号	3号
出版者	Wiley
開始ページ	146
終了ページ	149
ISSN	2049-4173
資料タイプ	学術雑誌論文
言語	English
OAI-PMH Set	岡山大学
論文のバージョン	author
DOI	10.1111/ncn3.12280
Web of Science KeyUT	000466785700011
関連URL	isVersionOf https://doi.org/10.1111/ncn3.12280

Transtibial pullout repair of medial meniscus posterior root tear restores physiological rotation of the tibia in the knee-flexed position

フルテキストURL	OTSR105_1_113.pdf Fig.pdf
著者	Okazaki, Yuki\| Furumatsu, Takayuki\| Kodama, Yuya\| Hino, Tomohito\| Kamatsuki, Yusuke\| Okazaki, Yoshiki\| Masuda, Shin\| Miyazawa, Shinichi\| Endo, Hirosuke\| Tetsunaga, Tomonori\| Yamada, Kazuki\| Ozaki, Toshifumi\|
キーワード	Magnetic resonance imaging Medial meniscus Posterior root tear Tibial rotation Transtibial pullout repair
発行日	2019-02-28
出版物タイトル	Orthopaedics & Traumatology: Surgery & Research
巻	105巻
号	1号
出版者	Elsevier
開始ページ	113
終了ページ	117
ISSN	18770568
資料タイプ	学術雑誌論文
言語	Japanese
OAI-PMH Set	岡山大学
論文のバージョン	author
PubMed ID	30482466
DOI	10.1016/j.otsr.2018.10.005
Web of Science KeyUT	000456541300019
関連URL	isVersionOf https://doi.org/10.1016/j.otsr.2018.10.005

Residual Femoral Deformity and Femoroacetabular Impingement after Intertrochanteric Osteotomy for Slipped Capital Femoral Epiphysis

JaLCDOI	10.18926/AMO/55308
フルテキストURL	71_4_315.pdf
著者	Fujii, Yosuke\| Endo, Hirosuke\| Mitani, Shigeru\| Akazawa, Hirofumi\| Tetsunaga, Tomonori\| Miyake, Takamasa\| Yamada, Kazuki\| Aoki, Kiyoshi\| Ozaki, Toshifumi\|
抄録	We retrospectively reviewed 29 hips in which intertrochanteric osteotomies were performed for severe slipped capital femoral epiphyses. Mean age at surgery: 12.6 years. Mean follow-up period: 6 years. At the final follow-up evaluation, one patient had coxalgia, and six hips showed a limited range of motion. A pistol-grip deformity was observed in 13 hips, osteoarthritis in two hips, and a bump existed in 19 hips on the latest radiographs. Gradual remodeling of the bumps was observed post-operatively in 22 hips. The mean α and β angles and offset α and β improved over time. The remodeling proceeded rapidly for 1 year post-surgery. We compared hips classified as β angles of ≥ 63° to < 63° at the final follow-up evaluation, the mean β angle 1 year post-surgery, and the mean ratio of improvement of the β angle per year from 1 year post-surgery to the final follow up, which differed significantly. Nearly all of the patients who underwent intertrochanteric osteotomies had residual morphologic abnormalities, but few had clinical symptoms. The β angle 1 year post-surgery and the ratio of remodeling of the bump from 1 year post-surgery to the final follow-up can be regarded as a potential predictor of morphologic results after intertrochanteric osteotomy.
キーワード	slipped capital femoral epiphyses intertrochanteric osteotomy residual femoral deformity femoroacetabular impingement bone remodeling
Amo Type	Original Article
発行日	2017-08
出版物タイトル	Acta Medica Okayama
巻	71巻
号	4号
出版者	Okayama University Medical School
開始ページ	315
終了ページ	323
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	English
著作権者	CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	28824187

An Analysis of the Characteristics and Improved Use of Newly Developed CT-based Navigation System in Total Hip Arthroplasty

JaLCDOI	10.18926/AMO/55304
フルテキストURL	71_4_279.pdf
著者	Fujii, Yosuke\| Fujiwara, Kazuo\| Tetsunaga, Tomonori\| Miyake, Takamasa\| Yamada, Kazuki\| Endo, Hirosuke\| Abe, Nobuhiro\| Sugita, Naohiko\| Mitsuishi, Mamoru\| Inoue, Takayuki\| Nakashima, Yoshio\| Ozaki, Toshifumi\|
抄録	We developed a surface matching-type computed tomography (CT)-based navigation system for total hip arthroplasty (the N-navi; TEIJIN NAKASHIMA MEDICAL, Okayama, Japan). In the registration step, surface matching was performed with digitizing points on the pelvic bone surface after coarse paired matching. In the present study, we made model bones from the CT data of patients whose acetabular shapes had various deformities. We measured the distances and angles after surface matching from the fiducial points and evaluated the ability to correct surface-matching registration on each pelvic form, using several areas and numbers of points. When the surface-matching points were taken on the superior area of the acetabulum, the correction was easy for the external direction, but it was difficult to correct for the anterior and proximal directions. The correction was difficult for external and proximal directions on the posterior area. Each area of surface-matching points has particular directions that are easily corrected and other directions that are difficult to correct. The shape of the pelvis also affected the correction ability. Our present findings suggest that checking the position after coarse paired matching and choosing the surface-matching area and points that are optimal to correct will improve the accuracy of total hip arthroplasty and reduce surgical times.
キーワード	total hip arthroplasty CT-based navigation system surface matching
Amo Type	Original Article
発行日	2017-08
出版物タイトル	Acta Medica Okayama
巻	71巻
号	4号
出版者	Okayama University Medical School
開始ページ	279
終了ページ	289
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	English
著作権者	CopyrightⒸ 2017 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	28824183

For Vol.69, No.4, pp205-212 Venous Thromboembolism after Total Hip Arthroplasty Diagnosed by Enhanced Computed Tomography : Comparison of Selective Thromboprophylaxis and No Thromboprophylaxis

JaLCDOI	10.18926/AMO/53680
フルテキストURL	69_5_325.pdf
著者	Okada, Yoshiki\| Endo, Hirosuke\| Mitani, Shigeru\| Fujiwara, Kazuo\| Tetsunaga, Tomonori\| Kagawa, Yohei\| Fujii, Yosuke\| Kunisada, Toshiyuki\| Ozaki, Toshifumi\|
抄録	Total hip arthroplasty (THA) is the most effective treatment for advanced or end-stage hip osteoarthritis. However, venous thromboembolism (VTE) remains one of its unresolved complications. We reviewed the records of 322 patients undergoing primary THA and investigated the efficacy of anticoagulant prophylaxis for VTE. Our study cohort consisted of 60 patients who received no anticoagulants, 100 patients who received a factor Xa inhibitor (fondaparinux), 100 patients who received low molecular weight heparin (enoxaparin), and 62 patients who selectively received no anticoagulant prophylaxis due to perioperative bleeding, weight, and/or hemoglobin concentration. Enhanced 64-slice multidetector row computed tomography was performed postoperatively for 7 days in all cases. The incidence of VTE in the four groups was 15%, 9.0%, 6.0%, and 6.4%, respectively. The incidence of VTE was significantly lower in the groups receiving anticoagulant prophylaxis and the group selectively receiving no anticoagulant prophylaxis than in the group receiving no anticoagulants. Complications of fondaparinux therapy included hepatic dysfunction in 4 cases (4.0%), minor bleeding in 2 cases (2.0%), persistent wound drainage in 3 cases (3.0%), and eruption in 1 case (1.0%). The complications of enoxaparin therapy were persistent wound drainage in 1 case (1.0%) and progression of anemia in 1 case (1.0%). The incidence of VTE was low in patients who selectively received no anticoagulant prophylaxis, so we conclude that anticoagulant prophylaxis should be used selectively in THA cases.
キーワード	total hip arthroplasty venous thromboembolism anticoagulant prophylaxis complications
Amo Type	Erratum
発行日	2015-10
出版物タイトル	Acta Medica Okayama
巻	69巻
号	5号
出版者	Okayama University Medical School
開始ページ	325
終了ページ	325
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	English
著作権者	CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	26490031
関連URL	http://doi.org/10.18926/AMO/53556

Venous Thromboembolism after Total Hip Arthroplasty Diagnosed by Enhanced Computed Tomography : Comparison of Selective Thromboprophylaxis and No Thromboprophylaxis

JaLCDOI	10.18926/AMO/53556
フルテキストURL	69_4_205.pdf
著者	Okada, Yoshiki\| Endo, Hirosuke\| Mitani, Shigeru\| Fujiwara, Kazuo\| Tetsunaga, Tomonori\| Kagawa, Yohei\| Fujii, Yosuke\| Kunisada, Toshiyuki\| Ozaki, Toshifumi\|
抄録	Total hip arthroplasty (THA) is the most effective treatment for advanced or end-stage hip osteoarthritis. However, venous thromboembolism (VTE) remains one of its unresolved complications. We reviewed the records of 322 patients undergoing primary THA and investigated the efficacy of anticoagulant prophylaxis for VTE. Our study cohort consisted of 60 patients who received no anticoagulants, 100 patients who received a factor Xa inhibitor (fondaparinux), 100 patients who received low molecular weight heparin (enoxaparin), and 62 patients who selectively received no anticoagulant prophylaxis due to perioperative bleeding, weight, and/or hemoglobin concentration. Enhanced 64-slice multidetector row computed tomography was performed postoperatively for 7 days in all cases. The incidence of VTE in the four groups was 15ｵ, 9.0ｵ, 6.0ｵ, and 6.4ｵ, respectively. The incidence of VTE was significantly lower in the groups receiving anticoagulant prophylaxis and the group selectively receiving no anticoagulant prophylaxis than in the group receiving no anticoagulants. Complications of fondaparinux therapy included hepatic dysfunction in 4 cases (4.0ｵ), minor bleeding in 2 cases (2.0ｵ), persistent wound drainage in 3 cases (3.0ｵ), and eruption in 1 case (1.0ｵ). The complications of enoxaparin therapy were persistent wound drainage in 1 case (1.0ｵ) and progression of anemia in 1 case (1.0ｵ). The incidence of VTE was low in patients who selectively received no anticoagulant prophylaxis, so we conclude that anticoagulant prophylaxis should be used selectively in THA cases.
キーワード	total hip arthroplasty venous thromboembolism anticoagulant prophylaxis complications
Amo Type	Original Article
発行日	2015-08
出版物タイトル	Acta Medica Okayama
巻	69巻
号	4号
出版者	Okayama University Medical School
開始ページ	205
終了ページ	212
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	English
著作権者	CopyrightⒸ 2015 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	26289911
Web of Science KeyUT	000365519100003
関連URL	http://doi.org/10.18926/AMO/53680

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