ID 56681
フルテキストURL
著者
Elgaml, Abdelaziz Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
Miyoshi, Shin-ichi Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University
抄録
Vibrio vulnificus is a halophilic estuarine bacterium, but this species causes fatal septicemia in humans. V. vulnificus may encounter many kinds of stresses either in the natural environment or in the human body. One of the striking stresses is the exposure to the reactive oxygen species including nitric oxide (NO). The present study revealed that NO could participate in the regulation of the V. vulnificus community behavior. When the bacterium was cultivated in the presence of sub-lethal doses of an NO donor, the expression of the genes encoding NO-detoxifying enzymes was significantly increased. The NO donor was also found to cause significant increase in production of a metalloprotease, a putative virulence factor, by the bacterium.
キーワード
Vibrio vulnificus
Nitric oxide
Oxidative stress
Detoxification
備考
Note
発行日
2015
出版物タイトル
Biocontrol Science
20巻
3号
出版者
The Society for Antibacterial and Antifungal Agents
開始ページ
199
終了ページ
203
ISSN
13424815
NCID
AA11169621
資料タイプ
学術雑誌論文
言語
English
OAI-PMH Set
岡山大学
論文のバージョン
Publisher
PubMed ID
DOI
Web of Science KeyUT
関連URL
isVersionOf https://doi.org/10.4265/bio.20.199
プロジェクト
インド感染症共同研究
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