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ID 17217
Eprint ID
17217
フルテキストURL
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タイトル(別表記)
Studies on platelet functions in myeloproliferative disorders Part 2. Studies on adenine nucleotides in platelet in myeloproliferative disorders
著者
野崎 宏幸 岡山大学医学部第2内科学教室
抄録
Abnormalities of platelet-function, particularly decrease of platelet aggregation, in myeloproliferative disorders have been already reported in Part 1 of this study. In this paper author studied a relationship between these abnormalities and Adenine Nucleotides (AN) in platelets. Materials were 26 cases of chronic myelocytic leukemia and 4 cases of polycythemia vera. AN in platelets (ADP, ATP) and released-AN (ADP, ATP) from platelets were assayed by Luciferin-Luciferase method. As results followings were obtained. In these myeloproliferative disorders, not only contents of ADP and ATP in platelets but also released-ADP and ATP have been significantly decreased. Furthermore, these cases have been classified into two groups: (i) cases, which showed decreased platelet aggregation and decrease of released-ADP and ATP due to decrease of contents of ADP and ATP in platelets. (ii) cases, which showed decreased platelet aggregation and decrease of released-ADP and ATP inspite of normal ADP and ATP contents in platelets. These results were thought to suggest that hemostatic abnormalities in myeloproliferative disorders might be classified into two categories, namely "Storage pool disease" and "Aspirin like release defect".
発行日
1977-10-30
出版物タイトル
岡山医学会雑誌
出版物タイトル(別表記)
Journal of Okayama Medical Association
89巻
9-10号
出版者
岡山医学会
出版者(別表記)
Okayama Medical Association
開始ページ
1203
終了ページ
1220
ISSN
0030-1558
NCID
AN00032489
資料タイプ
学術雑誌論文
オフィシャル URL
https://www.jstage.jst.go.jp/article/joma1947/89/9-10/89_9-10_1203/_article/-char/ja/
関連URL
http://www.okayama-u.ac.jp/user/oma/
言語
Japanese
著作権者
岡山医学会
論文のバージョン
publisher
査読
有り
Eprints Journal Name
joma