JaLCDOI 10.18926/AMO/71343
FullText URL 80_5_333.pdf
Author Yamamoto, Masahiro| Sada, Ken-ei| Kawada, Satoshi| Furihata, Taeko| Muramatsu, Sachiko| Miyamoto, Daichi| Yano, Akihiko| Miyashita, Kohei| Saisaka, Yuichi| Ishii, Takayuki|
Abstract A 79-year-old woman with severe fever with thrombocytopenia syndrome (SFTS) developed progressive atrioventricular (AV) conduction disturbances during hospitalization. On hospital day 6, first-degree AV block progressed to transient complete AV block, causing syncope and a 15-sec asystolic pause. Echocardiography showed preserved ventricular function, and cardiac magnetic resonance imaging did not support clinically overt myocarditis. A temporary transvenous pacemaker was inserted, and AV conduction recovered spontaneously; pacing was discontinued by day 9 without permanent pacemaker implantation. This case suggests that SFTS can cause reversible high-degree AV block and may warrant continuous twelve-lead electrocardiography (ECG) monitoring and timely temporary pacing.
Keywords severe fever with thrombocytopenia syndrome atrioventricular block bradyarrhythmia temporary pacing myocarditis
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2026-10
Volume volume80
Issue issue5
Publisher Okayama University Medical School
Start Page 333
End Page 337
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/71342
FullText URL 80_5_327.pdf
Author Hata, Yurika| Tabuchi, Motoyasu| Sakamoto, Shinya| Tamura, Shuta| Uemura, Sunao| Tokumaru, Teppei| Yoshimatu, Rika| Okabayashi, Takehiro|
Abstract A 67-year-old man presented with sudden-onset abdominal pain and hemorrhagic shock. Contrast-enhanced CT revealed a large hematoma in hepatic segments VI-VII with capsular rupture and hemoperitoneum. CT angiography demonstrated a saccular pseudoaneurysm in a posterior segmental branch of the right hepatic artery and a beaded appearance with irregular dilatation and segmental narrowing of the right hepatic artery branches, without inflammatory or atherosclerotic findings, supporting a diagnosis of segmental arterial mediolysis (SAM). Emergency angiography followed by coil embolization achieved hemostasis. Follow-up CT at 5 months showed complete exclusion of the aneurysmal lesions, with no evidence of recurrence or new vascular lesions. Coil embolization may be an effective, minimally invasive option for ruptured intrahepatic SAM lesions.
Keywords segmental arterial mediolysis hepatic artery intra-abdominal hemorrhage
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2026-10
Volume volume80
Issue issue5
Publisher Okayama University Medical School
Start Page 327
End Page 332
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/71341
FullText URL 80_5_317.pdf
Author Saito, Hayato| Fukui, Ryohei| Sugihara, Hanako| Tada, Akihiro| Nagao, Shoji| Iguchi, Toshihiro|
Abstract This study evaluated the feasibility of predicting pathogenic BRCA1/2 variants in ovarian cancer using radiogenomic analysis of contrast-enhanced MRI. Twenty six patients were analyzed, including 14 with pathogenic BRCA1/2 variants and 12 without. Contrast enhanced MRI was used to generate two dimensional (2D) and three dimensional (3D) tumor segmentations. Radiomic features extracted with PyRadiomics were reduced using least absolute shrinkage and selection operator (LASSO) regression, yielding two selected features. Linear discriminant analysis (LDA) models were trained on 18 patients and tested on 8, with performance assessed using sensitivity, specificity, accuracy, and the area under the receiver operating characteristic (ROC) curve. The DeLong test compared AUCs between segmentation methods. Automated machine learning (AutoML) was performed with a training set of 20 patients and a test set of 6, with multiple performance metrics calculated. LDA achieved approximately 60% accuracy in both 2D and 3D test datasets. AUCs were 0.80 (3D) and 0.77 (2D), with no significant difference (p=0.85). AutoML identified CatBoost_BAG_L2_FULL as the optimal model, achieving accuracy above 80%. MRI-based radiogenomic analysis demonstrated moderate classification performance for identifying pathogenic BRCA1/2 variants in ovarian cancer. These preliminary findings suggest a potential role for noninvasive prediction, warranting further validation in larger cohorts.
Keywords ovarian cancer BRCA1/2 radiogenomics machine learning MRI
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-10
Volume volume80
Issue issue5
Publisher Okayama University Medical School
Start Page 317
End Page 325
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/71340
FullText URL 80_5_309.pdf
Author Egashira, Saki| Nakano, Takafumi| Irie, Keiichi| Ushio, Soichiro| Manabe, Akiko| Masaki, Ayuko| Mukai, Rie| Nakamura, Yoshihiko| Hosokawa, Masato| Satho, Tomomitsu| Sano, Kazunori| Mishima, Kenichi|
Abstract This study examined the dynamics of serum amyloid A (SAA) levels in the blood, brain, and liver over time using a mouse model of focal cerebral ischemia induced by occlusion of the middle cerebral artery (MCA) for 4 h followed by reperfusion. Blood SAA concentrations increased transiently after cerebral infarction, coinciding with changes in brain and liver SAA gene expression and protein levels. SAA concentrations in the brain, liver, and blood increased at similar time points after cerebral infarction, suggesting that SAA may serve as an important indicator of the associated pathological condition.
Keywords stroke cerebral ischemia serum amyloid A temporal dynamics
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-10
Volume volume80
Issue issue5
Publisher Okayama University Medical School
Start Page 309
End Page 316
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/71339
FullText URL 80_5_299.pdf
Author Xu, Tao| Zheng, Ying| Huang, Xuemei| Luo, Hong|
Abstract This study evaluated the prognostic significance of the C-reactive protein–albumin–lymphocyte (CALLY) index and systemic immune-inflammation (SII) index in predicting postoperative outcomes in patients with esophageal squamous cell carcinoma (ESCC). A retrospective analysis was performed on clinical data from 102 patients with ESCC who underwent surgical resection at Western Theater General Hospital of China between January 2020 and July 2023. The associations between preoperative CALLY and SII indices and relapse-free survival (RFS) and overall survival (OS) were examined. Survival curves were generated using the Kaplan–Meier method, and prognostic factors were identified using Cox proportional hazards regression analysis. Patients with a high CALLY index had significantly longer RFS (HR=0.30, 95% CI: 0.13-0.71), and those with a low SII index also had significantly longer RFS (HR=2.23, 95% CI: 1.12-4.41). Similarly, patients with a high CALLY index had significantly longer OS (HR=0.27, 95% CI: 0.13-0.55), and those with a low SII index had significantly longer OS (HR=2.27, 95% CI: 1.09-4.71). When patients were stratified into four groups, the low-CALLY–high-SII group showed significantly shorter RFS than the high-CALLY–low-SII group (HR=0.26, 95% CI: 0.11-0.61; p=0.013), and OS was also significantly worse in the low-CALLY–high-SII group (HR=0.22, 95% CI: 0.09-0.54; p=0.016). Univariate Cox regression analysis identified both CALLY and SII as significant prognostic factors. In multivariate analysis, the CALLY index and N stage were independently associated with RFS, whereas only tumor size remained independently associated with OS. The combined assessment of preoperative CALLY and SII indices may be useful for prognostic stratification in patients with ESCC undergoing upfront surgical resection. It may help identify high-risk patient subgroups with distinct survival outcomes, thereby providing a potential rationale for stratifying postoperative surveillance and tailoring individualized adjuvant strategies, although validation in larger prospective cohorts is warranted.
Keywords CALLY index SII index esophageal squamous cell carcinoma prognosis
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-10
Volume volume80
Issue issue5
Publisher Okayama University Medical School
Start Page 299
End Page 308
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/71338
FullText URL 80_5_289.pdf
Author Komuta, Yuki| Imai, Norio| Homma, Daisuke| Funayama, Kazuhisa| Hirano, Yuki| Horigome, Yoji| Minato, Izumi| Kawashima, Hiroyuki|
Abstract The “CR Alignment” function was recently introduced in ZedHip®, the hip joint module of ZedView®, to evaluate pelvic tilt in non-supine positions via two-dimensional (2D)‒3D matching using radiographs. However, its ccuracy has not been validated. This study therefore evaluated the accuracy of pelvic tilt measurements using the CR Alignment function in dry pelvic bone specimens. Two cadaveric pelvic bone models were placed in nine orientations (anterior/posterior tilt and left/right rotation). Both radiographic and CT images were acquired in each position. In Study 1, pelvic tilt measured directly from CT images was defined as the “true value.” Three observers used the CR Alignment function to calculate pelvic tilt on radiographs, and measurement errors were determined relative to the true values. In Study 2, measurement errors were compared between matched (same position) and mismatched (different position) imaging. In Study 1, the mean measurement error was 1.28±0.64°. Intra- and interobserver intraclass correlation coefficients were 0.996-0.998 and 0.997, respectively. In Study 2, the mean errors were 1.20±0.88° (matched) and 1.32±1.03° (mismatched). This software exhibited high accuracy and reproducibility in 2D‒3D matching of pelvic tilt, with lower variability under matched acquisition, demonstrating its utility for pre- and postoperative assessment in joint arthroplasty.
Keywords total hip arthroplasty pelvic tilt three-dimensional planning software two-dimensional and threedimensional matching radiographic analysis
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-10
Volume volume80
Issue issue5
Publisher Okayama University Medical School
Start Page 289
End Page 298
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/71337
FullText URL 80_5_279.pdf
Author Miyamoto, Satoshi| Matsumoto, Naomi| Mitsuhashi, Toshiharu| Takao, Soshi| Yorifuji, Takashi|
Abstract Diabetes mellitus is a well-established risk factor for severe COVID-19; however, few studies have examined this association during the Omicron-dominant period. We conducted a population-based study using surveillance data from the Okayama City Public Health Center in Japan to compare the risk of severe COVID-19 and pneumonia among patients with diabetes mellitus between the pre-Omicron (March 2020–December 2021) and Omicron-dominant (January–September 2022) periods. Among 98,905 COVID-19 patients aged 10 years or older, we calculated adjusted odds ratios (aORs) controlling for age, sex, smoking status, comorbidities, obesity, and the number of COVID-19 vaccine doses received. In the pre-Omicron period, diabetes mellitus was significantly associated with severe COVID-19 (aOR: 1.36; 95% CI: 1.03-1.78), and this association persisted in the Omicron-dominant period (aOR: 1.54; 95% CI: 1.10-2.17). Similar findings were observed for pneumonia. The association was more pronounced among patients aged 40-69 years than among those aged 70 years or older. These findings suggest that diabetes mellitus remains an important risk factor for severe COVID-19 even during the Omicron-dominant period, highlighting the need for continued clinical vigilance and early intervention in patients with diabetes mellitus.
Keywords COVID-19 diabetes mellitus Omicron variant severity population-based study
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-10
Volume volume80
Issue issue5
Publisher Okayama University Medical School
Start Page 279
End Page 288
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
JaLCDOI 10.18926/AMO/71336
FullText URL 80_5_271.pdf
Author Sato, Ryosuke| Matsumoto, Kazuyuki| Otsuka, Motoyuki|
Abstract Peroral cholangioscopy (POCS) enables direct intraductal visualization and targeted biopsies for indeterminate biliary strictures. However, its diagnostic performance remains operator-dependent and is limited by sampling error. As artificial intelligence (AI) has rapidly advanced in gastrointestinal endoscopy, AI-assisted cholangioscopy has progressed from proof-of-concept image classification to multicenter validation, feature detection, and real-time application. Recent studies using digital single-operator cholangioscopy have reported diagnostic accuracy comparable to that of experts in differentiating malignant from benign strictures, and feature-based approaches can automatically detect tumor vessels and other key visual characteristics. Beyond classification, generative models may enhance mucosal and margin visualization through virtual chromoendoscopy, potentially improving lesion-margin assessment. Furthermore, new models compatible with multiple systems are emerging to address device heterogeneity, which is a key barrier to routine practice. This review summarizes the current evidence on AI-assisted POCS, discusses practical considerations for clinical translation, and highlights future directions, including real-time integration and multimodal decision support.
Keywords peroral cholangioscopy artificial intelligence biliary stricture deep learning virtual chromoendoscopy
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2026-10
Volume volume80
Issue issue5
Publisher Okayama University Medical School
Start Page 271
End Page 277
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
FullText URL fulltext_20261019-01.pdf
Author Hanaya, Tadashi| Yamamoto, Hiroshi|
Note This is the peer reviewed version of the following article: Hanaya, T. and Yamamoto, H. (2002), A New Route for Preparation of 5-Deoxy-5-(hydroxyphosphinyl)- D-mannopyranose and -L-gulopyranose Derivatives. HCA, 85: 2608-2618. https://doi.org/10.1002/1522-2675(200209)85:9<2608::AID-HLCA2608>3.0.CO;2-F, which has been published in final form at https://doi.org/10.1002/1522-2675(200209)85:9<2608::AID-HLCA2608>3.0.CO;2-F. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.|
Published Date 2002-09
Publication Title Helvetica Chimica Acta
Volume volume85
Issue issue9
Publisher Wiley
Start Page 2608
End Page 2618
ISSN 0018-019X
NCID AA00663251
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2002 Neue Schweizerische Chemische Gesellschaft, Switzerland
File Version author
DOI 10.1002/1522-2675(200209)85:9<2608::aid-hlca2608>3.0.co;2-f
Web of Science KeyUT 000178628100003
Related Url isVersionOf https://doi.org/10.1002/1522-2675(200209)85:9<2608::aid-hlca2608>3.0.co;2-f
FullText URL fulltext.pdf
Author Nagashima, Satomu| Taniguchi, Masaharu| Taylor, George|
Keywords Traveling front V-form Reaction–diffusion equation
Published Date 2026-10-15
Publication Title Partial Differential Equations and Applications
Volume volume7
Issue issue6
Publisher Springer Science and Business Media LLC
Start Page 48
ISSN 2662-2963
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2026
File Version publisher
DOI 10.1007/s42985-026-00410-0
Related Url isVersionOf https://doi.org/10.1007/s42985-026-00410-0
FullText URL fulltext.pdf
Author Hisano, Hiroshi|
Keywords CRISPR/Cas9 genome editing Hordeum vulgare plant breeding transformation amenability
Published Date 2026-09
Publication Title Contig
Volume volume1
Issue issue3
Publisher Kazakhstan Society of Geneticists and Breeders
Start Page 202615
ISSN 3134-6359
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 Hiroshi Hisano.
File Version publisher
DOI 10.66273/3134-6359.2026.1.3.003
Related Url isVersionOf https://doi.org/10.66273/3134-6359.2026.1.3.003
FullText URL fulltext.pdf
Author Huong, Ngo Thanh| Kodama, Susumu| Ono, Atsushi|
Keywords Arsenic toxicity Nrf2 activator QSAR modeling Food-derived compounds In vitro
Published Date 2026
Publication Title The Journal of Toxicological Sciences
Volume volume51
Issue issue10
Publisher Japanese Society of Toxicology
Start Page 533
End Page 547
ISSN 0388-1350
NCID AN00002808
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 Author(s)
File Version publisher
PubMed ID 42816373
DOI 10.2131/jts.51.533
CRID 1390309758326043520
Related Url isVersionOf https://doi.org/10.2131/jts.51.533
FullText URL fulltext.pdf
Author Huaman Palomino, Katia Sara| Hirata, Yoshitsugu|
Keywords acculturation intensive surveillance Japan maternal identity Peruvian migration reflexive continuity Third Space transnational motherhood
Published Date 2026-10-12
Publication Title Frontiers in Sociology
Volume volume11
Publisher Frontiers Media SA
Start Page 1944754
ISSN 2297-7775
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 Huaman Palomino and Hirata.
File Version publisher
DOI 10.3389/fsoc.2026.1944754
Related Url isVersionOf https://doi.org/10.3389/fsoc.2026.1944754
FullText URL fulltext.pdf
Author Thongin, Thanyamai| Sermkaew, Namfa| Atipairin, Apichart| Krobthong, Sucheewin| Aonbangkhen, Chanat| Uchiyama, Jumpei| Songnaka, Nuttapon|
Keywords Brevibacillus sp. antimicrobial peptide AMP mangrove genome anti-MRSA
Published Date 2026-10-10
Publication Title Life
Volume volume16
Issue issue10
Publisher MDPI AG
Start Page 1697
ISSN 2075-1729
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 by the authors.
File Version publisher
DOI 10.3390/life16101697
Related Url isVersionOf https://doi.org/10.3390/life16101697
FullText URL fulltext.pdf
Author Geng, Tingting| Kajiwara, Yuki| Morimoto, Michiko|
Keywords chronic kidney disease self-efficacy self-care cultural adaptation psychometric evaluation exploratory structural equation modeling
Published Date 2026-10-12
Publication Title Healthcare
Volume volume14
Issue issue20
Publisher MDPI AG
Start Page 3393
ISSN 2227-9032
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 by the authors.
File Version publisher
DOI 10.3390/healthcare14203393
Related Url isVersionOf https://doi.org/10.3390/healthcare14203393
Author Mimura, Souta| Kanda, Takefumi| Yamaguchi, Daisuke| Kubo, Kazuki| Wakimoto, Shuichi|
Note This is an Accepted Manuscript of an article published by IOP Publishing.| This fulltext file will be available in Apr. 2027.|
Published Date 2026-04-06
Publication Title Japanese Journal of Applied Physics
Volume volume65
Issue issue7
Publisher IOP Publishing
Start Page 07SP13
ISSN 0021-4922
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Japan Society of Applied Physics.
File Version author
DOI 10.35848/1347-4065/ae5116
Web of Science KeyUT 001733382700001
Related Url isVersionOf https://doi.org/10.35848/1347-4065/ae5116
FullText URL fulltext20261014-01.pdf
Author Hanaya, Tadashi| Imai, Kumiko| Prikhod’ko, Yurij V.| Yamamoto, Hiroshi|
Keywords Phospho sugar 6-Deoxy-6-phosphinyl-d-fructopyranose Hydroxyphosphinyl group Acetyl migration Conformational analysis
Note © 2004 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/|
Published Date 2005-01-17
Publication Title Carbohydrate Research
Volume volume340
Issue issue1
Publisher Elsevier BV
Start Page 31
End Page 37
ISSN 0008-6215
NCID AA00598932
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2004 Elsevier Ltd.
File Version author
PubMed ID 15620664
DOI 10.1016/j.carres.2004.10.020
Web of Science KeyUT 000226538800004
Related Url isVersionOf https://doi.org/10.1016/j.carres.2004.10.020
FullText URL fulltext.pdf
Author Shibuya, Kohjiro| Matsumura, Kentarou| Miyatake, Takahisa|
Keywords Avoiding attack Beetle Playing dead Thanatosis Post-contact immobility Tonic immobility
Published Date 2026-10-07
Publication Title Journal of Ethology
Publisher Springer Science and Business Media LLC
ISSN 0289-0771
NCID AA10754455
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2026
File Version publisher
DOI 10.1007/s10164-026-00905-8
Related Url isVesionOf https://doi.org/10.1007/s10164-026-00905-8
FullText URL fulltext.pdf
Author Sato, Kazuhiro| Morita, Maho| Yamaji, Nami| Kako, Rinka| Ushijima, Tomokazu| Hisano, Hiroshi|
Keywords Cinnamyl Alcohol Dehydrogenase (CAD) Barley Orange lemma Lignin Genome editing
Published Date 2026-07-04
Publication Title Scientific Reports
Volume volume16
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 30805
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2026
File Version publisher
PubMed ID 42401638
DOI 10.1038/s41598-026-59416-8
Related Url isVersionOf https://doi.org/10.1038/s41598-026-59416-8
FullText URL fulltext.pdf
Author Tanabe, Shihori| Quader, Sabina| Ono, Ryuichi| Tanaka, Hiroyoshi Y.| Cabral, Horacio|
Keywords coronavirus EIF2 signaling microRNA molecular pathway network activation
Published Date 2026-02-04
Publication Title International Journal of Molecular Sciences
Volume volume27
Issue issue3
Publisher MDPI AG
Start Page 1525
ISSN 1422-0067
NCID AA12038549
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 by the authors.
File Version publisher
PubMed ID 41683944
DOI 10.3390/ijms27031525
CRID 1871434918649812352
Related Url isVesionOf https://doi.org/10.3390/ijms27031525