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タイトル(別表記) Case Concerning Certain Property, Preliminary Objections, Judgment of 10 February 2005
フルテキストURL olj_055_1_208_191.pdf
著者 玉田 大|
出版物タイトル 岡山大學法學會雜誌
発行日 2005-09-30
55巻
1号
開始ページ 208
終了ページ 191
ISSN 0386-3050
言語 日本語
論文のバージョン publisher
NAID 120005372649
タイトル(別表記) Affaire relative à la licéité de l'emploi de la force, Exceptions préliminaires, Arrêt du 15 décembre 2004.
フルテキストURL olj_055_1_228_209.pdf
著者 玉田 大|
出版物タイトル 岡山大學法學會雜誌
発行日 2005-09-30
55巻
1号
開始ページ 228
終了ページ 209
ISSN 0386-3050
言語 日本語
論文のバージョン publisher
NAID 120005372650
JaLCDOI 10.18926/AMO/52145
フルテキストURL 68_1_53.pdf
著者 Terasaka, Tomohiro| Ueta, Eijiro| Ebara, Hirotaka| Waseda, Koichi| Hanayama, Yoshihisa| Takaki, Akinobu| Kawabata, Tomoko| Sugiyama, Hitoshi| Hidan, Ko| Otsuka, Fumio|
抄録 A 64-year-old man suffering polyarthralgia and bone pain was referred to our hospital. Renal dysfunction, hypophosphatemia and increased levels of bone alkaline phosphatase were found. The patientʼs serum creatinine level had gradually increased after the initiation of adefovir dipivoxil administration for hepatitis B. In agreement with multifocal uptakes of bone scintigraphy, iliac bone biopsy revealed an abnormal increase in osteoid tissues. Reducing the dose of adefovir and initiating the administration of eldecalcitol were effective for reducing proteinuria and glucosuria, and for ameliorating bone pain with an increase in serum phosphate level. This case first showed a clinical course of hypophosphatemic osteomalacia caused by secondary Fanconiʼs syndrome for 8 years after adefovir administration. Early diagnosis is important for the reversibility of bone damage and for a better renal prognosis.
キーワード adefovir dipivoxil (ADV) eldecalcitol Fanconi's syndrome hypophosphatemia osteomalacia
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2014-02
68巻
1号
出版者 Okayama University Medical School
開始ページ 53
終了ページ 56
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24553490
JaLCDOI 10.18926/AMO/52144
フルテキストURL 68_1_47.pdf
著者 Ishikawa, Tsutomu| Araki, Motoo| Hirata, Takeshi| Watanabe, Masami| Ebara, Shin| Watanabe, Toyohiko| Nasu, Yasutomo| Kumon, Hiromi|
抄録 We report 3 patients with the rare complication of an indwelling urethral catheter misdirected into the ureter. This is the largest series to date. Patients were referred to us for a variety of reasons following exchange of their chronic indwelling urinary catheters. CT in all cases demonstrated the urinary catheters residing in the left ureter. The ages of the patients were 37, 67 and 81 years old. All patients suffered from neurogenic bladder. Two patients were female, one was male, and 2 of the 3 had a sensory disorder inhibiting their pain response. The catheters were replaced with open-end Foley catheters. Extensive follow-up CT scans were obtained in one case, demonstrating improvement of hydronephrosis and no evidence of ureteral stenosis. Cystoscopy in this patient demonstrated normally positioned and functioning ureteral orifices. Although the placement of an indwelling urethral catheter is a comparatively safe procedure, one must keep in mind that this complication can occur, particularly in female patients with neurogenic bladder. CT without contrast is a noninvasive, definitive diagnostic tool.
キーワード complication indwelling urethral catheter imaging computed tomography ureter
Amo Type Case Report
出版物タイトル Acta Medica Okayama
発行日 2014-02
68巻
1号
出版者 Okayama University Medical School
開始ページ 47
終了ページ 51
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24553489
Web of Science KeyUT 000331592800008
JaLCDOI 10.18926/AMO/52143
フルテキストURL 68_1_43.pdf
著者 Miyatake, Nobuyuki| Shikata, Kenichi| Makino, Hirofumi| Numata, Takeyuki|
抄録 The link between lifestyle modification and changes in both proteinuria and estimated glomerular filtration rates (eGFRs) was evaluated in Japanese subjects with proteinuria who were not taking medications. We used data from 51 men (35.8±10.0 years) and 74 women (38.0±11.0 years) with proteinuria at baseline and a 1-year follow up. eGFR was defined by a new equation developed specifically for Japanese subjects. Subjects were given advice for dietary and lifestyle improvement at the initial appointment. At the 1-year follow up, eGFR was increased in both sexes, but not at significant levels. (men:p=0.7709, women:p=0.2180). Proteinuria was also improved in many subjects. A decrease in proteinuria may be associated with improving eGFR in Japanese.
キーワード proteinuria estimated glomerular filtration rate (eGFR) lifestyle modification
Amo Type Short Communication
出版物タイトル Acta Medica Okayama
発行日 2014-02
68巻
1号
出版者 Okayama University Medical School
開始ページ 43
終了ページ 46
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24553488
Web of Science KeyUT 000331592800007
JaLCDOI 10.18926/AMO/52142
フルテキストURL 68_1_35.pdf
著者 Araki, Motoo| Jeong, Wooju| Park, Sung Yul| Lee, Young Hoon| Nasu, Yasutomo| Kumon, Hiromi| Hong, Sung Joon| Rha, Koon Ho|
抄録 The purpose of this study was to compare the positive surgical margin (PSM) rates of 2 techniques of robot-assisted radical prostatectomy (RARP) for pT2 (localized) prostate cancer. A retrospective analysis was conducted of 361 RARP cases, performed from May 2005 to September 2008 by a single surgeon (KHR) at our institution (Yonsei University College of Medicine). In the conventional technique, the bladder neck was transected first. In the modified ultradissection, the lateral border of the bladder neck was dissected and then the bladder neck was transected while the detrusor muscle of the bladder was well visualized. Perioperative characteristics and outcomes and PSM rates were analyzed retrospectively for pT2 patients (n=217), focusing on a comparison of those undergoing conventional (n=113) and modified ultradissection (n=104) techniques. There was no difference between the conventional and modified ultradissection group in mean age, BMI, PSA, prostate volume, biopsy Gleason score, and DʼAmico prognostic criteria distributions. The mean operative time was shorter (p<0.001) and the estimated blood loss was less (p<0.01) in the modified ultradissection group. The PSM rate for the bladder neck was significantly reduced by modified ultradissection, from 6.2% to 0% (p<0.05). In conclusion, modified ultradissection reduces the PSM rate for the bladder neck.
キーワード robot-assisted radical prostatectomy prostate cancer surgery surgical margin technique
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2014-02
68巻
1号
出版者 Okayama University Medical School
開始ページ 35
終了ページ 41
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24553487
Web of Science KeyUT 000331592800006
JaLCDOI 10.18926/AMO/52141
フルテキストURL 68_1_27.pdf
著者 Yoshida, Masao| Ishikawa, Mamoru| Karita, Kanae| Kokaze, Akatsuki| Harada, Matsuko| Take, Shinichiro| Ohno, Hideki|
抄録 To clarify whether high blood pressure (BP) and high body mass index (BMI) are associated with elevated intraocular pressure (IOP), a cross-sectional and longitudinal study was conducted. This epidemiological study analyzed health examination data obtained between 2001 and 2005 from 896 Japanese individuals (aged 32-79 years) who had not undergone any ocular surgery or medical treatment for hypertension, ocular hypertension, or glaucoma. Multiple-regression analysis of our cross-sectional data showed that systolic and diastolic BP (SBP and DBP) and BMI had significant and near-significant positive associations with IOP in men (p<0.05) and women (p<0.1). Our longitudinal study from analyses of covariance found that the adjusted mean level of changes in IOP tended to increase with increased levels of SBP, DBP, and BMI in men (p<0.1). In women also, changes in SBP and BMI tended to be positively related with that of IOP (p<0.1). The results of this study suggested that BP and BMI were positively associated with IOP in middle-aged and older Japanese. Therefore, management of BP and improvement of obesity might be especially important to Japanese patients with open-angle glaucoma or ocular hypertension as they have a higher incidence of normal-tension glaucoma than Europeans and Americans.
キーワード intraocular pressure blood pressure body mass index epidemiology glaucoma
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2014-02
68巻
1号
出版者 Okayama University Medical School
開始ページ 27
終了ページ 34
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24553486
Web of Science KeyUT 000331592800005
JaLCDOI 10.18926/AMO/52140
フルテキストURL 68_1_23.pdf
著者 Ueno, Tsuyoshi| Toyooka, Shinichi| Fukazawa, Takuya| Kubo, Takafumi| Soh, Junichi| Asano, Hiroaki| Muraoka, Takayuki| Tanaka, Norimitsu| Maki, Yuho| Shien, Kazuhiko| Furukawa, Masashi| Sakaguchi, Masakiyo| Yamamoto, Hiromasa| Tsukuda, Kazunori| Miyoshi, Shinichiro|
抄録 The microRNA-34s (miR-34s) have p53 response elements in their 5ʼ-flanking regions and demonstrate tumor-suppressive functions. In malignant pleural mesothelioma (MPM), we previously reported that expression of miR-34b and miR-34c (miR-34b/c) was frequently downregulated by methylation in MPM cell lines and primary tumors. The forced overexpression of miR-34b/c showed significant antitumor effects with the induction of apoptosis in MPM cells. In this study, we examined the in vivo antitumor effects of miR-34b/c using adenovirus vector on MPM. We subcutaneously transplanted NCI-H290, a human MPM cell line, into BALB/C mice and injected adenovirus vector expressing miR-34b/c, luciferase driven by the cytomegalovirus promoter (Ad-miR-34b/c or Ad-Luc), or PBS control into tumors over 5mm in diameter. A statistically significant growth inhibition of the tumor volume was observed in the Ad-miR-34b/c group from day 6 onward compared to the Ad-Luc group. The inhibition rate of Ad-miR-34b/c, compared to the tumor volume treated with Ad-Luc, was 58.6% on day 10 and 54.7% on day13. Our results indicate that adenovirus-mediated miR-34b/c gene therapy could be useful for the clinical treatment of MPM.
キーワード mesothelioma microRNA microRNA-34b/c p53
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2014-02
68巻
1号
出版者 Okayama University Medical School
開始ページ 23
終了ページ 26
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24553485
Web of Science KeyUT 000331592800004
JaLCDOI 10.18926/AMO/52139
フルテキストURL 68_1_17.pdf
著者 Moritou, Yuki| Ikeda, Fusao| Iwasaki, Yoshiaki| Baba, Nobuyuki| Takaguchi, Kouichi| Senoh, Tomonori| Nagano, Takuya| Takeuchi, Yasuto| Yasunaka, Tetsuya| Ohnishi, Hideki| Miyake, Yasuhiro| Takaki, Akinobu| Nouso, Kazuhiro| Yamamoto, Kazuhide|
抄録 The impact of hepatic steatosis on interferon therapy for patients with chronic hepatitis C (CHC) has been associated with single-nucleotide polymorphisms (SNP) of IL28B, patatin-like phospholipase domain-containing protein 3 (PNPLA3), and low-density lipoprotein (LDL) receptor. Whether this holds true for Japanese patients, however, remains unresolved. The present study prospectively enrolled 226 Japanese patients with CHC, and investigated the impact of hepatic steatosis and its related SNPs, including rs8099917 of IL28B, rs738409 of PNPLA3, and rs14158 of LDL receptor, on outcomes of peg-interferon and ribavirin therapy. In multivariate logistic regression analysis, significant factors affecting the severity of hepatic steatosis were high body mass index and the minor alleles of IL28B SNP (p=0.020 and 0.039, respectively). The risk alleles of PNPLA3 SNP also showed weak association (p=0.059). Severe steatosis and the minor alleles of IL28B SNP were significantly associated with null or partial virological response in patients with HCV genotype 1, as were female gender, and low LDL cholesterol (p=0.049, and <0.001, respectively). The SNP genotype of PNPLA3 and LDL receptor did not have a significant impact on therapeutic outcomes. With respect to the SNP sites examined, the SNP of PNPLA3 has a weak association with severe hepatic steatosis, but not with the outcome of interferon therapy.
キーワード hepatic steatosis genetic polymorphism interferon HCV
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2014-02
68巻
1号
出版者 Okayama University Medical School
開始ページ 17
終了ページ 22
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24553484
Web of Science KeyUT 000331592800003
JaLCDOI 10.18926/AMO/52138
フルテキストURL 68_1_7.pdf
著者 Horimoto, Naoya| Kitamura, Shinji| Tsuji, Kenji| Makino, Hirofumi|
抄録 Immunosuppressive agents are generally administered to treat kidney diseases. However, it is unclear whether renal stem/progenitor cells are directly affected by the immunosuppressive agents. We used normal rat kidney cells, ureteric bud cells and rat kidney stem/progenitor cells in this study. Mizoribine (MZR), cyclophosphamide (CPA) and cyclosporine (CyA) were added to the culture media of these cells. We evaluated the effects of these immunosuppressive agents on cell proliferation using an electrical cell-substrate impedance sensing system (ECIS) and their effects on the process of renal regeneration using the ischemia-reperfusion (I/R) injury rat model. The ECIS data showed that proliferation of each of the 3 types of cells was significantly suppressed by MZR. MZR treatment enhanced renal tubular injury in ischemia-reperfusion (I/R) injured rats, and significantly decreased levels of M-phase cells and Nestin-positive cells. These results suggested that MZR inhibits the cell cycle of renal stem/progenitor cells;thus, physicians should take note that MZR might affect not only inflammation but also renal regeneration.
キーワード cell biology immunosuppression stem cells
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2014-02
68巻
1号
出版者 Okayama University Medical School
開始ページ 7
終了ページ 15
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24553483
Web of Science KeyUT 000331592800002
関連URL http://ousar.lib.okayama-u.ac.jp/metadata/52247
JaLCDOI 10.18926/AMO/52137
フルテキストURL 68_1_1.pdf
著者 Tanihara, Shinichi| Imatoh, Takuya| Momose, Yoshito|
抄録 Setting public health priorities requires precise estimation of the burden of disease, including disease-specific medical expenditure. Information on multiple and ruled-out diagnoses on health insurance claims (HICs) has been ignored in traditional analyses of disease-specific medical expenditures in Japan. This study reviewed 448 inpatients with at least one diagnosis of sepsis on their HICs, who were insured by corporate health insurance organizations making claims on services provided from April 2006 to March 2007 in Japan. Subjects in whom sepsis-related diagnoses were specified as “ruled-out” were compared with subjects in whom sepsis-related diagnoses were classified as “not-ruled-out” (i.e., subjects in whom sepsis was considered possibly or likely present). Direct medical expenditure, length of stay (LOS), cost per day, cost of antibiotics, and proportion of administered cephalosporin and carbapenems were significantly higher in subjects classified as not-rule-out. When using health insurance claims in Japan, the statistics of medical expenditures and LOS are influenced by procedures performed to rule out a diagnosis, as well as those performed to treat a confirmed diagnosis of sepsis.
キーワード health insurance claims length of stay medical expenditures ruled-out diagnoses sepsis
Amo Type Original Article
出版物タイトル Acta Medica Okayama
発行日 2014-02
68巻
1号
出版者 Okayama University Medical School
開始ページ 1
終了ページ 6
ISSN 0386-300X
NCID AA00508441
資料タイプ 学術雑誌論文
言語 英語
著作権者 CopyrightⒸ 2014 by Okayama University Medical School
論文のバージョン publisher
査読 有り
PubMed ID 24553482
Web of Science KeyUT 000331592800001
著者 杉浦 裕子| 曽我 賢彦| 前田 嘉信|
発行日 2010-09-01
出版物タイトル 造血細胞移植now&future
20巻
資料タイプ 一般雑誌記事
著者 岡山大学教育学部社会科地理学教室|
発行日 1982
出版物タイトル 岡大教育社会地理巡検シリーズ
9巻
資料タイプ 図書
著者 岡山大学教育学部社会科地理学教室|
発行日 1979
出版物タイトル 岡大教育社会地理巡検シリーズ
8巻
資料タイプ 図書
著者 岡山大学教育学部社会科地理学教室|
発行日 1973
出版物タイトル 岡大教育社会地理巡検シリーズ
7巻
資料タイプ 図書
著者 岡山大学教育学部社会科地理学教室|
発行日 1971
出版物タイトル 岡大教育社会地理巡検シリーズ
6巻
資料タイプ 図書
著者 岡山大学教育学部社会科地理学教室|
発行日 1965
出版物タイトル 岡大教育社会地理巡検シリーズ
4巻
資料タイプ 図書
著者 岡山大学農学部|
発行日 2014-02-01
出版物タイトル 岡山大学農学部学術報告
103巻
資料タイプ その他
著者 岡山大学農学部|
発行日 2014-02-01
出版物タイトル 岡山大学農学部学術報告
103巻
資料タイプ その他
著者 岡山大学農学部|
発行日 2014-02-01
出版物タイトル 岡山大学農学部学術報告
103巻
資料タイプ その他