検索結果 - 岡山大学学術成果リポジトリ

Surveillance of Pathogenicity of Rhizoctonia solani Japanese Isolates with Varied Anastomosis Groups and Subgroups on Arabidopsis thaliana

フルテキストURL	fulltext.pdf
著者	Abdelghany, Mai Mohsen Ahmed\| Kurikawa, Maria\| Watanabe, Megumi\| Matsui, Hidenori\| Yamamoto, Mikihiro\| Ichinose, Yuki\| Toyoda, Kazuhiro\| Kouzai, Yusuke\| Noutoshi, Yoshiteru\|
キーワード	Rhizoctonia solani anastomosis group phytohormones pathogenicity Arabidopsis thaliana
発行日	2022-01-06
出版物タイトル	Life-Basel
巻	12巻
号	1号
出版者	MDPI
開始ページ	76
ISSN	2075-1729
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 by the authors.
論文のバージョン	publisher
PubMed ID	35054469
DOI	10.3390/life12010076
Web of Science KeyUT	000746520800001
関連URL	isVersionOf https://doi.org/10.3390/life12010076

Diffuse Large B-Cell Lymphoma 18 Years After Bilateral Lacrimal Gland IgG4-Related Disease: Case Report and Literature Review

フルテキストURL	fulltext20220121.pdf
著者	Matsuo, Toshihiko\| Tanaka, Takehiro\| Notohara, Kenji\| Okada, Kazuya\|
キーワード	IgG4-related disease lacrimal gland diffuse large B-cell lymphoma re-immunostaining literature review
発行日	2022-1
出版物タイトル	Journal of Investigative Medicine High Impact Case Reports
巻	10巻
出版者	SAGE Publications
開始ページ	1
終了ページ	10
ISSN	2324-7096
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2022 American Federation for Medical Research
論文のバージョン	publisher
DOI	10.1177/23247096211067894

Estimation of periodontal pocket surface area in small to medium dogs: a proof-of-concept study

フルテキストURL	fulltext.pdf
著者	Tamura, Kazuya\| Tokuzen-Tai, Masako\| Siddiqui, Yasir Dilshad\| Tamura-Naito, Hitomi\| Nagahara, Yoshiharu\| Hatanaka-Takeuchi, Kazu\| Yamamoto, Tadashi\| Takashiba, Shogo\|
キーワード	Dog Periodontitis Periodontal pocket surface area Estimation method Periodontology
発行日	2022-01-03
出版物タイトル	BMC Veterinary Research
巻	18巻
号	1号
出版者	BMC
開始ページ	13
ISSN	1746-6148
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2021.
論文のバージョン	publisher
PubMed ID	34980120
DOI	10.1186/s12917-021-03116-0
Web of Science KeyUT	000737982200010
関連URL	isVersionOf https://doi.org/10.1186/s12917-021-03116-0

Upregulation of a nuclear factor-kappa B-interacting immune gene network in mice cochleae with age-related hearing loss

フルテキストURL	fulltext.pdf
著者	Uraguchi, Kensuke\| Maeda, Yukihide\| Takahara, Junko\| Omichi, Ryotaro\| Fujimoto, Shohei\| Kariya, Shin\| Nishizaki, Kazunori\| Ando, Mizuo\|
発行日	2021-10-22
出版物タイトル	PLOS ONE
巻	16巻
号	10号
出版者	Public Library Science
開始ページ	e0258977
ISSN	1932-6203
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 Uraguchi et al.
論文のバージョン	publisher
PubMed ID	34679122
DOI	10.1371/journal.pone.0258977
Web of Science KeyUT	000733392900043
関連URL	isVersionOf https://doi.org/10.1371/journal.pone.0258977

Efficacy of shear wave elasticity for evaluating myocardial hypertrophy in hypertensive rats

フルテキストURL	fulltext.pdf
著者	Takaya, Yoichi\| Nakamura, Kazufumi\| Nakayama, Rie\| Ohtsuka, Hiroaki\| Amioka, Naofumi\| Kondo, Megumi\| Akazawa, Kaoru\| Ohno, Yuko\| Ichikawa, Keishi\| Saito, Yukihiro\| Akagi, Satoshi\| Yoshida, Masashi\| Miyoshi, Toru\| Ito, Hiroshi\|
発行日	2021-11-24
出版物タイトル	Scientific Reports
巻	11巻
号	1号
出版者	Nature Portfolio
開始ページ	22812
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2021
論文のバージョン	publisher
PubMed ID	34819579
DOI	10.1038/s41598-021-02271-6
Web of Science KeyUT	000722365800023
関連URL	isVersionOf https://doi.org/10.1038/s41598-021-02271-6

Sarcomatoid hepatocellular carcinoma is distinct from ordinary hepatocellular carcinoma: Clinicopathologic, transcriptomic and immunologic analyses

フルテキストURL	K0006480_abstract_review.pdf K0006480_fullext.pdf K0006480_other1_Table.pdf K0006480_other2_Supplementary Material.pdf K0006480_other3_Supplementary Table.pdf
著者	森末遼\|
発行日	2021-09-24
資料タイプ	学位論文
学位授与番号	甲第6480号
学位授与年月日	2021-09-24
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語
著作権者	© 2021 Union for International Cancer Control.

Protective effects of edaravone on white matter pathology in a novel mouse model of Alzheimer's disease with chronic cerebral hypoperfusion

フルテキストURL	K0006477_abstract_review.pdf K0006477_fulltext.pdf
著者	馮田\|
発行日	2021-09-24
資料タイプ	学位論文
学位授与番号	甲第6477号
学位授与年月日	2021-09-24
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語

Effects of luseogliflozin on estimated plasma volume in patients with heart failure with preserved ejection fraction

フルテキストURL	fulltext.pdf
著者	Nakashima, Mitsutaka\| Miyoshi, Toru\| Ejiri, Kentaro\| Kihara, Hajime\| Hata, Yoshiki\| Nagano, Toshihiko\| Takaishi, Atsushi\| Toda, Hironobu\| Nanba, Seiji\| Nakamura, Yoichi\| Akagi, Satoshi\| Sakuragi, Satoru\| Minagawa, Taro\| Kawai, Yusuke\| Nishii, Nobuhiro\| Fuke, Soichiro\| Yoshikawa, Masaki\| Nakamura, Kazufumi\| Ito, Hiroshi\| MUSCAT-HF Study Investigators\|
キーワード	Estimated plasma volume Heart failure with preserved ejection fraction Luseogliflozin Sodium glucose co-transporter 2 inhibitors Voglibose
発行日	2021-11-03
出版物タイトル	Esc Heart Failure
出版者	Wiley Periodicals, Inc
ISSN	2055-5822
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 The Authors.
論文のバージョン	publisher
DOI	10.1002/ehf2.13683
Web of Science KeyUT	000714002000001
関連URL	isVersionOf https://doi.org/10.1002/ehf2.13683

Proof of Concept of the Yadokari Nature: a Capsidless Replicase-Encoding but Replication-Dependent Positive-Sense Single-Stranded RNA Virus Hosted by an Unrelated Double-Stranded RNA Virus

フルテキストURL	fulltext20211102-1.pdf
著者	Das, Subha\| Alam, Md Mahfuz\| Zhang, Rui\| Hisano, Sakae\| Suzuki, Nobuhiro\|
備考	This is an Accepted Manuscript of an article published by American Society for Microbiology.\|
発行日	2021-8-10
出版物タイトル	Journal of Virology
巻	95巻
号	17号
出版者	American Society for Microbiology
開始ページ	e00467-21
ISSN	0022-538X
NCID	AA00708779
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2021 American Society for Microbiology.
論文のバージョン	author
PubMed ID	34106772
DOI	10.1128/jvi.00467-21
Web of Science KeyUT	000708640500015
関連URL	isVersionOf https://doi.org/10.1128/jvi.00467-21

Relationship between clinical outcomes and nerve conduction studies before and after surgery in patients with carpal tunnel syndrome

フルテキストURL	fulltext.pdf
著者	Ise, Masato\| Saito, Taichi\| Katayama, Yoshimi\| Nakahara, Ryuichi\| Shimamura, Yasunori\| Hamada, Masanori\| Senda, Masuo\| Ozaki, Toshifumi\|
キーワード	Carpal tunnel syndrome Nerve conduction study The disability of the arm shoulder and hand questionnaire Clinical outcomes
発行日	2021-10-16
出版物タイトル	BMC Musculoskeletal Disorders
巻	22巻
号	1号
出版者	BMC
開始ページ	882
ISSN	1471-2474
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2021.
論文のバージョン	publisher
PubMed ID	34656102
DOI	10.1186/s12891-021-04771-y
Web of Science KeyUT	000707702900001
関連URL	isVersionOf https://doi.org/10.1186/s12891-021-04771-y

Clinical Efficacy and Safety of Sitafloxacin 200 mg Once Daily for Refractory Genitourinary Tract Infections

JaLCDOI	10.18926/AMO/62820
フルテキストURL	75_6_763.pdf
著者	Iwata, Takehiro\| Sadahira, Takuya\| Maruyama, Yuki\| Sekito, Takanori\| Yoshinaga, Kasumi\| Watari, Shogo\| Nagao, Kentaro\| Kawada, Tatsushi\| Tominaga, Yusuke\| Nishimura, Shingo\| Takamoto, Atsushi\| Sako, Tomoko\| Edamura, Kohei\| Kobayashi, Yasuyuki\| Araki, Motoo\| Ishii, Ayano\| Watanabe, Masami\| Watanabe, Toyohiko\| Nasu, Yasutomo\| Wada, Koichiro\|
抄録	The aim of this ongoing trial is to evaluate the clinical efficacy and safety of sitafloxacin (STFX) 200 mg once daily (QD) for 7 days in patients with refractory genitourinary tract infections, which include recurrent or complicated cystitis, complicated pyelonephritis, bacterial prostatitis, and epididymitis. The primary endpoint is the microbiological efficacy at 5-9 days after the last administration of STFX. Recruitment began in February 2021, and the target total sample size is 92 participants.
キーワード	genitourinary tract infections fluoroquinolone resistance extended-spectrum beta-lactamase
Amo Type	Clinical Study Protocol
出版物タイトル	Acta Medica Okayama
発行日	2021-12
巻	75巻
号	6号
出版者	Okayama University Medical School
開始ページ	763
終了ページ	766
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34955548
Web of Science KeyUT	000735319800006
NAID	120007180272

Pulmonary Enteric Adenocarcinoma Harboring a BRAF G469V Mutation

JaLCDOI	10.18926/AMO/62819
フルテキストURL	75_6_759.pdf
著者	Shimizu, Dai\| Yamamoto, Hiromasa\| Shien, Kazuhiko\| Taniguchi, Kohei\| Miyoshi, Kentaroh\| Namba, Kei\| Mesaki, Kumi\| Sugimoto, Seiichiro\| Soh, Junichi\| Yamane, Masaomi\| Toyooka, Shinichi\|
抄録	Pulmonary enteric adenocarcinoma (PEAC) is a rare subtype of lung cancer that should be differentiated from colorectal cancer metastasis. Little is known about its genetic background. An 84-year-old male with adenocarcinoma of the lung underwent left upper lobectomy. The histology of the surgical specimen was suggestive of PEAC. Gastrointestinal and colorectal fiberscopy revealed no evidence of colorectal cancer. Next-generation sequencing of the tumor identified a G469V substitution in serine/threonine-protein kinase B-raf (BRAF). Based on the higher prevalence of the G469 substitution in BRAF-mutant lung adenocarcinoma than in BRAFmutant colorectal cancer, the tumor likely originated from the lung. Identification of mutational genotype may be of some help in distinguishing PEAC from the lung metastasis of colorectal cancer.
キーワード	non-small cell lung cancer somatic mutations pulmonary adenocarcinoma with enteric differentiation non-V600E BRAF mutation next-generation sequencing
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-12
巻	75巻
号	6号
出版者	Okayama University Medical School
開始ページ	759
終了ページ	762
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34955547
Web of Science KeyUT	000735319800005
NAID	120007180273

Left Hemihepatectomy for Hepatocellular Carcinoma Following Esophagectomy with Retrosternal Gastric Tube Reconstruction for Esophageal Cancer

JaLCDOI	10.18926/AMO/62818
フルテキストURL	75_6_755.pdf
著者	Takagi, Kosei\| Kuise, Takashi\| Umeda, Yuzo\| Yoshida, Ryuichi\| Yoshida, Kazuhiro\| Nagai, Yasuo\| Noma, Kazuhiro\| Tanabe, Shunsuke\| Maeda, Naoaki\| Yagi, Takahito\| Fujiwara, Toshiyoshi\|
抄録	Approximately 4% of patients with esophageal cancer develop a second primary malignancy in the upper gastrointestinal trunk. However, hepatectomy following esophagectomy for esophageal cancer has rarely been reported. We report the case of a 70-year-old man who underwent an esophagectomy for esophageal cancer with retrosternal gastric tube reconstruction. Nine years later, he developed hepatocellular carcinoma with tumor thrombus involving the left portal vein, and was successfully treated with left hemihepatectomy. Special attention should be paid to avoiding incidental injury of the gastric tube as well as the right gastroepiploic artery during the hepatectomy.
キーワード	liver resection, esophagectomy, retrosternal gastric tube reconstruction
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-12
巻	75巻
号	6号
出版者	Okayama University Medical School
開始ページ	755
終了ページ	758
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34955546
Web of Science KeyUT	000735319800004
NAID	120007180274

Non-Invasive Prenatal Genetic Testing (NIPT) Leading to Prenatal Diagnosis of Trisomy 21 Mosaicism and 18q Deletion Syndrome: Two Cases

JaLCDOI	10.18926/AMO/62816
フルテキストURL	75_6_745.pdf
著者	Hayata, Kei\| Mishima, Sakurako\| Ohira, Akiko\| Tani, Kazumasa\| Maki, Jota\| Eto, Eriko\| Ogawa, Chikako\| Masuyama, Hisashi\|
抄録	NIPT is non-definitive testing to estimate the possibility that fetuses have trisomy 21, trisomy 18, or trisomy 13. However, in NIPT-positive and indeterminate cases, rare chromosomal disease may become apparent, requiring advanced genetic considerations and counseling skills. We experienced two such cases, a trisomy 21 mosaicism case triggered by NIPT-positive status and 18q deletion syndrome triggered by NIPT-indeterminate status. These cases have two clinical implications for NIPT. First, it was revealed that trisomy mosaicism might be found in NIPT-positive cases that have lower Z-Scores than those inferred from the fraction of fetal cfDNA in the case of standard trisomy. Second, it is possible that microdeletion syndrome could be the reason for an indeterminate NIPT result. Today’s genetic counseling requires more expertise in ethics and communication as well as genetic science because NIPT can lead to totally unexpected results.
キーワード	NIPT massively parallel sequencing trisomy 21 mosaicism 18q-deletion syndrome genetic counseling
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-12
巻	75巻
号	6号
出版者	Okayama University Medical School
開始ページ	745
終了ページ	750
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34955544
Web of Science KeyUT	000735319800002
NAID	120007180276

Sublingual Gland Carcinoma Revealed by Choroidal Metastasis

JaLCDOI	10.18926/AMO/62815
フルテキストURL	75_6_741.pdf
著者	Morita, Tetsuro\| Shiode, Yusuke\| Kimura, Shuhei\| Hosokawa, Mio\| Doi, Shinichiro\| Takahashi, Kosuke\| Matoba, Ryo\| Kanzaki, Yuki\| Tabata, Masahiro\| Morizane, Yuki\|
抄録	A 65-year-old man presented with a 1-week history of left eye distortion. An elevated choroidal lesion covering 6 disc diameters was found in the posterior retina of the left eye. Systemic examination revealed sublingual gland carcinoma and multiple lung metastases, and the diagnosis was choroidal metastasis from sublingual gland carcinoma. Following chemotherapy and radiation therapy, the choroidal lesion shrunk and the patient’s visual acuity improved. The patient died 23 months after his first visit. To the best of our knowledge, this is the first reported case of choroidal metastasis from sublingual gland carcinoma.
キーワード	adenoid cystic carcinoma choroidal metastasis sublingual gland
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-12
巻	75巻
号	6号
出版者	Okayama University Medical School
開始ページ	741
終了ページ	744
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34955543
Web of Science KeyUT	000735319800001
NAID	120007180277

Multiple Hepatolithiasis Following Hepaticojejunostomy Successfully Treated with Left Hemihepatectomy and Double Hepaticojejunostomy Reconstruction

JaLCDOI	10.18926/AMO/62814
フルテキストURL	75_6_735.pdf
著者	Nagai, Yasuo\| Takagi, Kosei\| Kuise, Takashi\| Umeda, Yuzo\| Yoshida, Ryuichi\| Yoshida, Kazuhiro\| Yasui, Kazuya\| Yagi, Takahito\| Fujiwara, Toshiyoshi\|
抄録	Surgical intervention for hepatolithiasis following hepaticojejunostomy (HJ) has rarely been reported. Herein, we present a case of post-HJ multiple hepatolithiasis treated with left hemihepatectomy with double HJ reconstruction. A 72-year-old woman who had undergone HJ for iatrogenic bile duct injury developed repeated cholangitis due to complicated hepatolithiasis accompanied by an atrophied left hepatic lobe and HJ stricture. Since endoscopic intervention was unsuccessful, the patient underwent left hemihepatectomy with HJ re-anastomoses of the common hepatic duct and left hepatic duct (double HJ technique). The double HJ technique with hepatectomy can be a useful option for treating complicated hepatolithiasis following HJ.
キーワード	hepatolithiasis hepaticojejunostomy hepatectomy
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2021-12
巻	75巻
号	6号
出版者	Okayama University Medical School
開始ページ	735
終了ページ	739
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34955542
Web of Science KeyUT	000735297900009
NAID	120007180278

Morphological Changes and Durability of Skin and Mucosal Flaps in Intraoral and Pharyngeal Reconstructions: Long-term Follow-up and Literature Review for Potential Second Carcinomas

JaLCDOI	10.18926/AMO/62813
フルテキストURL	75_6_725.pdf
著者	Matsumoto, Hiroshi\| Kimata, Yoshihiro\| Ota, Tomoyuki\| Sugiyama, Narushi\| Onoda, Satoshi\| Makino, Takuma\| Takeda, Seiko\| Mizukawa, Nobuyoshi\|
抄録	The long-term changes in tissues implanted in the oral cavity and pharynx after head and neck reconstruction have not been fully evaluated. This study aimed to clarify the morphological changes, long-term durability, and potential for secondary carcinogenesis in such tissues. In our single-center study, the rough morphological changes in 54 cases of intraoral and pharyngeal skin and mucosal flaps were evaluated more than 10 years after flap transfer. In addition, the literature on the development of second carcinomas from skin flaps was reviewed. The mean follow-up period for transferred flaps was 148 months. The reconstruction areas and the probability of morphological changes were significantly correlated (p=0.006), especially in cases with tongue, lower gingiva, and buccal mucosal reconstruction. Free jejunal flap surfaces were well maintained, whereas tubed skin flaps showed severe morphological changes in cases with pharyngeal reconstruction. None of the flaps in our series developed second primary carcinomas. Skin flaps generally had good durability for > 10 years in intraoral environments, while mucosal flaps had better durability for pharyngeal reconstruction. Second squamous carcinomas arising from skin flaps are extremely rare; however, surgeons should take this possibility into consideration and conduct meticulous and long-term follow-up.
キーワード	skin flap mucosal flap oral reconstruction morphological change second primary carcinoma
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-12
巻	75巻
号	6号
出版者	Okayama University Medical School
開始ページ	725
終了ページ	734
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34955541
NAID	120007180279

The Significance of Age and Causative Bacterial Morphology in the Choice of an Antimicrobial Agent to Treat Acute Uncomplicated Cystitis

JaLCDOI	10.18926/AMO/62812
フルテキストURL	75_6_719.pdf
著者	Uehara, Shinya\| Fujio, Kei\| Yamasaki, Tomoya\| Otsuki, Hideo\|
抄録	Differentiating patients by age and causative bacterial morphology might aid in making the appropriate choice of antimicrobial agent when treating acute uncomplicated cystitis. In this retrospective analysis, the non-susceptibility rates of the causative bacteria to cefcapene-pivoxil (CFPN-PI) and levofloxacin (LVFX) were determined after dividing patients with acute uncomplicated cystitis by age group (15-54 and 55-74 years old) and by bacterial morphology: gram-positive cocci (GPC) or gram-negative rod (GNR). The overall non-susceptibility rates for CFPN-PI and LVFX were 19.4% and 15.3%, respectively. When the subjects were divided by age, only the non-susceptibility rate for LVFX in the younger group significantly decreased (to 8.7%). When the groups were divided by both age and bacterial morphology, the younger GNR group had non-susceptibility rates of 6.9% to CFPN-PI and 7.8% to LVFX, whereas the younger GPC group showed 10.2% non-susceptibility to LVFX. The older GNR group showed 9.8% non-susceptibility to CFPN-PI, while the older GPC group showed 7.2% non-susceptibility to LVFX. All the non-susceptibility rates were lower than 10.2% in the sub-divided groups. Differentiating patients by age and the morphology of causative bacteria can aid in making the appropriate choice of antimicrobial agent and may improve treatment outcomes in patients with acute uncomplicated cystitis.
キーワード	acute uncomplicated cystitis oral antimicrobial agents antimicrobial susceptibility menopause Gram stain
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-12
巻	75巻
号	6号
出版者	Okayama University Medical School
開始ページ	719
終了ページ	724
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34955540
Web of Science KeyUT	000735297900008
NAID	120007180280

Correlations Among Consistency, Computed Tomography Values, and Histopathological Subtypes of Spinal Meningioma

JaLCDOI	10.18926/AMO/62811
フルテキストURL	75_6_713.pdf
著者	Aoyama, Tatsuro\| Ogiwara, Toshihiro\| Ito, Kiyoshi\| Miyaoka, Yoshinari\| Fujii, Yu\| Hanaoka, Yoshiki\| Hasegawa, Takatoshi\| Watanabe, Gen\| Seguchi, Tatsuya\| Hongo, Kazuhiro\|
抄録	The consistency of spinal meningiomas is important to consider when performing tumor removal surgery. This study evaluated the correlations between spinal meningioma consistency and both preoperative computed tomography (CT) values and histopathological subtypes. Fifteen consecutive patients who underwent surgical resection of spinal meningioma at our institution were identified, and preoperative CT values and the signal intensity of T2-weighted magnetic resonance images of the tumor were determined retrospectively. The consistency of the spinal meningioma was defined based on the ultrasonic surgical aspirator output during tumor debulking. Patients were assigned to 2 groups: a soft group (n=4) and a hard group (n=11). The T2 signal intensity was significantly higher in the soft group than in the hard group (p=0.001). While the CT values were considerably higher in the hard group, the difference was not significant (p=0.19). Regarding the histopathological subtypes, psammomatous meningioma exhibited significantly higher CT values than meningothelial meningioma (p=0.019); however, there was a higher frequency of hard tumors in meningothelial meningioma cases than in psammomatous meningioma cases. Although neither robust correlations between tumor consistency and CT values nor a relationship between tumor consistency and histopathological subtype has been established, these results might help with the perioperative manegement of spinal tumors.
キーワード	calcification computed tomography psammoma body spinal meningioma
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-12
巻	75巻
号	6号
出版者	Okayama University Medical School
開始ページ	713
終了ページ	718
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34955539
Web of Science KeyUT	000735297900007
NAID	120007180281

Testosterone Recovery after Neoadjuvant Gonadotropin-Releasing Hormone Antagonist versus Agonist on Permanent Iodine-125 Seed Brachytherapy in Prostate Cancer Patients: A Propensity Score Analysis

JaLCDOI	10.18926/AMO/62810
フルテキストURL	75_6_705.pdf
著者	Iwata, Takehiro\| Maruyama, Yuki\| Kawada, Tatsushi\| Sadahira, Takuya\| Katayama, Satoshi\| Takamoto, Atsushi\| Sako, Tomoko\| Wada, Koichiro\| Edamura, Kohei\| Kobayashi, Yasuyuki\| Araki, Motoo\| Watanabe, Masami\| Watanabe, Toyohiko\| Nasu, Yasutomo\|
抄録	Optimal neoadjuvant hormone therapy (NHT) for reducing prostate cancer (PC) patients’ prostate volume pre-brachytherapy is controversial. We evaluated the differential impact of neoadjuvant gonadotropin-releasing hormone (GnRH) antagonist versus agonist on post-brachytherapy testosterone recovery in 112 patients treated pre-brachytherapy with NHT (GnRH antagonist, n=32; GnRH agonists, n=80) (Jan. 2007-June 2019). We assessed the effects of patient characteristics and a GnRH analogue on testosterone recovery with logistic regression and a propensity score analysis (PSA). There was no significant difference in the rate of testosterone recovery to normal levels (> 300 ng/dL) between the GnRH antagonist and agonists (p=0.07). The GnRH agonists induced a significantly more rapid testosterone recovery rate at 3 months post-brachytherapy versus the GnRH antagonist (p<0.0001); there was no difference in testosterone recovery at 12 months between the GnRH antagonist/agonists (p=0.8). In the multivariate analysis, no actor was associated with testosterone recovery. In the PSA, older age and higher body mass index (BMI) were significantly associated with longer testosterone recovery. Post-brachytherapy testosterone recovery was quicker with the neoadjuvant GnRH agonists than the antagonist, and the testosterone recovery rate was significantly associated with older age and higher BMI. Long-term follow-ups are needed to determine any differential effects of GnRH analogues on the quality of life of brachytherapy-treated PC patients.
キーワード	testosterone recovery GnRH antagonist GnRH agonist brachytherapy prostate cancer
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2021-12
巻	75巻
号	6号
出版者	Okayama University Medical School
開始ページ	705
終了ページ	711
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2021 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	34955538
Web of Science KeyUT	000735297900006
NAID	120007180282