検索結果 - 岡山大学学術成果リポジトリ

Obese Patient with Gastric Diverticulum Undergoing Laparoscopic Sleeve Gastrectomy Guided by Preoperative Endoscopic Measurement: A Case Report and Literature Review

フルテキストURL	fulltext.pdf
著者	Hirosuna, Kensuke\| Kashima, Hajime\| Shoji, Ryohei\| Matsumi, Yuki\| Kakiuchi, Yoshihiko\| Kikuchi, Satoru\| Kuroda, Shinji\| Teraishi, Fuminori\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
キーワード	obese patient gastric diverticulum sleeve gastrectomy metabolic surgery bariatric surgery endoscopic measurement
発行日	2025
出版物タイトル	Surgical Case Reports
巻	11巻
号	1号
出版者	Japan Surgical Society
開始ページ	cr.25-0141
ISSN	2198-7793
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 The Author(s).
論文のバージョン	publisher
PubMed ID	40511451
DOI	10.70352/scrj.cr.25-0141
Web of Science KeyUT	001533538200002
関連URL	isVersionOf https://doi.org/10.70352/scrj.cr.25-0141

The Asia-Pacific Body Mass Index Classification and New-Onset Chronic Kidney Disease in Non-Diabetic Japanese Adults: A Community-Based Longitudinal Study from 1998 to 2023

フルテキストURL	fulltext.pdf suppl.pdf
著者	Okawa, Yukari\| Mitsuhashi, Toshiharu\| Tsuda, Toshihide\|
キーワード	body mass index chronic kidney disease East Asian longitudinal studies risk factors
発行日	2025-02-05
出版物タイトル	Biomedicines
巻	13巻
号	2号
出版者	MDPI AG
開始ページ	373
ISSN	2227-9059
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 by the authors.
論文のバージョン	publisher
PubMed ID	40002785
DOI	10.3390/biomedicines13020373
Web of Science KeyUT	001431052500001
関連URL	isVersionOf https://doi.org/10.3390/biomedicines13020373

Mimicking Contralateral Pneumothorax during Thoracoscopic Bullectomy Associated with Intraoperative Hyperinflation of a Large Bulla in an Obese Patient

JaLCDOI	10.18926/AMO/69159
フルテキストURL	79_4_311.pdf
著者	Matsubara, Kei\| Matsubara, Kei\| Hirano, Yutaka\| Fujiwara, Toshiya\|
抄録	A 55-year-old obese Japanese male with left pneumothorax presented to our hospital. Bilateral pulmonary emphysema was confirmed. Persistent air leakage was observed, and a thoracoscopic bullectomy was performed. Although the thoracoscopic bullectomy was completed uneventfully, pre-extubation chest X-ray imaging indicated hyper-lucency occupying the right upper part of the thoracic cavity, suggesting right-sided pneumothorax. CT imaging indicated a right-upper-lobe expanded bulla. Extubation was performed, and the hyperinflated bulla gradually deflated. Careful management of bulla expansion and respiratory status may be necessary for patients with obesity and large bullae, especially in one-lung ventilation cases.
キーワード	giant bulla pneumothorax obesity positive pressure ventilation one lung ventilation
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2025-08
巻	79巻
号	4号
出版者	Okayama University Medical School
開始ページ	311
終了ページ	315
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り

Femoral and Global Femoral Offset, but not Anteroposterior Offset, to Improve Postoperative Outcomes Following Total Hip Arthroplasty: Considerations Independent of the Contralateral Side

JaLCDOI	10.18926/AMO/69152
フルテキストURL	79_4_269.pdf
著者	Imai, Norio\| Hirano, Yuki\| Homma, Daisuke\| Endo, Yuki\| Horigome, Yoji\| Suzuki, Hayato\| Kawashima, Hiroyuki\|
抄録	The global femoral offset (the sum of the acetabular and femoral offsets) influences outcomes after total hip arthroplasty (THA). The optimal offset using plain radiographs has been reported, but internal and external rotations of the hip affect the offset value, producing unclear results when the nonsurgical side is not intact. We investigated the relationship between a functional hip score, i.e., the Harris Hip Score (HHS) and its effect on the post-THA anteroposterior and lateral offsets, and we sought to identify the optimal offset value. The cases of 158 patients with hemilateral hip osteoarthritis who underwent THA at a single center were retrospectively analyzed in this cross-sectional study. Three-dimensional pelvic and femoral models generated from computed tomography were used to examine several parameters, and the results revealed a significant binomial correlation among the modified HHS and femoral and global femoral offsets, with maximum values of 21.3 mm and 40 mm/100 cm body height, respectively. Pelvic and femoral parameters were measured and evaluated via alignment with a specific coordinate system. Our findings indicate that preoperative planning using these parameters may improve postoperative hip function, even when the nonoperative side is unsuitable for use as a reference, as in bilateral hip osteoarthritis cases.
キーワード	total hip arthroplasty global femoral offset postoperative outcome three-dimensional analysis anteroposterior offset
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2025-08
巻	79巻
号	4号
出版者	Okayama University Medical School
開始ページ	269
終了ページ	278
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り

Maternal circadian rhythms during pregnancy dictate metabolic plasticity in offspring

フルテキストURL	fulltext.pdf suppl1.pdf suppl2.xlsx suppl3.xlsx suppl4.xlsx suppl5.xlsx suppl6.xlsx suppl7-1.xlsx suppl7-2.pdf suppl8.pdf
著者	Yao, Na\| Kinouchi, Kenichiro\| Katoh, Manami\| Ashtiani, Kousha Changizi\| Abdelkarim, Sherif\| Morimoto, Hiroyuki\| Torimitsu, Takuto\| Kozuma, Takahide\| Iwahara, Akihide\| Kosugi, Shotaro\| Komuro, Jin\| Kato, Kyosuke\| Tonomura, Shun\| Nakamura, Toshifumi\| Itoh, Arata\| Yamaguchi, Shintaro\| Yoshino, Jun\| Irie, Junichiro\| Hashimoto, Hisayuki\| Yuasa, Shinsuke\| Satoh, Akiko\| Mikami, Yohei\| Uchida, Shusaku\| Ueki, Takatoshi\| Nomura, Seitaro\| Baldi, Pierre\| Hayashi, Kaori\| Itoh, Hiroshi\|
キーワード	circadian rhythm metabolism circadian clock pregnancy developmental origins of health and disease obesity leptin time-restricted feeding caloric restriction eating behavior
発行日	2025-02
出版物タイトル	Cell Metabolism
巻	37巻
号	2号
出版者	Elsevier BV
開始ページ	395
終了ページ	412.e6
ISSN	1550-4131
NCID	AA11978571
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 The Authors.
論文のバージョン	publisher
PubMed ID	39814018
DOI	10.1016/j.cmet.2024.12.002
Web of Science KeyUT	001427175300001
関連URL	isVersionOf https://doi.org/10.1016/j.cmet.2024.12.002

(+)-Terrein exerts anti-obesity and anti-diabetic effects by regulating the differentiation and thermogenesis of brown adipocytes in mice fed a high-fat diet

フルテキストURL	fulltext.pdf suppl1.docx suppl2.jpg suppl3.jpg
著者	Aoki-Saito, Haruka\| Mandai, Hiroki\| Nakakura, Takashi\| Sasaki, Tsutomu\| Kitamura, Tadahiro\| Omori, Kazuhiro\| Hisada, Takeshi\| Okada, Shuichi\| Suga, Seiji\| Yamada, Masanobu\| Saito, Tsugumichi\|
キーワード	(+)-Terrein Brown adipose tissue Thermogenesis Obesity PPARγ
発行日	2025-05
出版物タイトル	Biomedicine & Pharmacotherapy
巻	186巻
出版者	Elsevier BV
開始ページ	118030
ISSN	0753-3322
NCID	AA10506249
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 The Author(s).
論文のバージョン	publisher
PubMed ID	40187045
DOI	10.1016/j.biopha.2025.118030
関連URL	isVersionOf https://doi.org/10.1016/j.biopha.2025.118030

Association between the Pretreatment Body Mass Index and Anamorelin’s Efficacy in Patients with Cancer Cachexia: A Retrospective Cohort Study

JaLCDOI	10.18926/AMO/68644
フルテキストURL	79_2_065.pdf
著者	Maki, Masatoshi\| Takada, Ryo\| Ishigo, Tomoyuki\| Fujiwara, Miki\| Takahashi, Yoko\| Otsuka, Shinya\| Tamura, Koji\| Hamaoka, Terutaka\|
抄録	Anamorelin (ANAM) is used to treat cancer-associated cachexia, a syndrome involving muscle loss and anorexia. The timing of the initiation of ANAM treatment is crucial to its efficacy. Although the body mass index (BMI) is a diagnostic criterion for cancer cachexia, no studies have explored its association with ANAM efficacy. We conducted a single-center, retrospective cohort study to investigate the association between the pre-treatment BMI and ANAM efficacy in patients with cancer-associated cachexia (n=47). The ANAM treatment was considered effective if the patient’s appetite improved within 30 days of treatment initiation. We calculated a BMI cutoff value (19.5 kg/m2) and used it to divide the patients into high- and low-BMI groups. Their background, clinical laboratory values, cancer types, and treatment lines were investigated. Twenty (42.6%) had a high BMI (≥ 19.5 kg/m2) and 27 (57.4%) had a low BMI (< 19.5 kg/m2). High BMI was significantly associated with ANAM effectiveness (odds ratio 7.86, 95% confidence interval 1.99-31.00, p=0.003). Together these results indicate that it is beneficial to initiate ANAM treatment before a patient’s BMI drops below 19.5 kg/m2. Our findings will help advance cancer cachexia treatment and serve as a reference for clinicians to predict ANAM’s efficacy.
キーワード	anamorelin cancer-associated cachexia body mass index albumin efficacy rate
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2025-04
巻	79巻
号	2号
出版者	Okayama University Medical School
開始ページ	65
終了ページ	73
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	40302277
Web of Science KeyUT	001485544200001

Serum uric acid level is associated with renal arteriolar hyalinosis and predicts post-donation renal function in living kidney donors

フルテキストURL	fulltext.pdf
著者	Kano, Yuzuki\| Tanabe, Katsuyuki\| Kitagawa, Masashi\| Sugiyama, Hitoshi\| Yamanoi, Tomoaki\| Yoshinaga, Kasumi\| Bekku, Kensuke\| Nishimura, Shingo\| Araki, Motoo\| Wada, Jun\|
発行日	2025-03-25
出版物タイトル	PLoS ONE
巻	20巻
号	3号
出版者	Public Library of Science
開始ページ	e0320482
ISSN	1932-6203
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2025 Kano et al.
論文のバージョン	publisher
PubMed ID	40131973
DOI	10.1371/journal.pone.0320482
Web of Science KeyUT	001456889900024
関連URL	isVersionOf https://doi.org/10.1371/journal.pone.0320482

Gastrectomy Causes an Imbalance in the Trunk Muscles

JaLCDOI	10.18926/AMO/68354
フルテキストURL	79_1_009.pdf
著者	Ikeya, Nanami\| Okita, Atsushi\| Hashida, Shinsuke\| Yamamoto, Sumiharu\| Ikeda, Hirokuni\| Tsukuda, Kazunori\| Toyooka, Shinichi\|
抄録	Muscle loss negatively affects gastrectomy prognosis. However, muscle loss is recognized as a systemic change, and individual muscle function is often overlooked. We investigated changes in the muscle volume of individual muscles after gastrectomy to identify clues for prognostic factors and optimal rehabilitation programs. Patients who underwent R0 gastrectomy for Stage I gastric cancer at our hospital from 2015 to 2021 were retrospectively selected to minimize the effects of malignancy and chemotherapy. Trunk muscle volume was measured by computed tomography to analyze body composition changes. Statistical analysis was performed to identify risk factors related to body composition changes. We compared the preoperative and 6-month postoperative conditions of 59 patients after gastrectomy. There was no difference in the psoas major muscle, a conventional surrogate marker of sarcopenia. There were significant decreases in the erector spinae (p=0.01) and lateral abdominal (p=0.01) muscles, and a significant increase in the rectus abdominis muscle (p=0.02). No significant correlation was found between these muscle changes and nutritional status. Body composition imbalance may serve as a new indicator of the general condition of patients after gastrectomy. Rehabilitation to correct this imbalance may improve prognosis after gastrectomy.
キーワード	sarcopenia skeletal muscle gastric cancer gastrectomy erector spinae muscle
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2025-02
巻	79巻
号	1号
出版者	Okayama University Medical School
開始ページ	9
終了ページ	19
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2025 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	40012155
Web of Science KeyUT	001440463800002

Cesarean delivery on child health and development in Japanese nationwide birth cohort

フルテキストURL	fulltext.pdf
著者	Matsumoto, Naomi\| Mitsui, Takashi\| Tamai, Kei\| Hirota, Tomoya\| Masuyama, Hisashi\| Yorifuji, Takashi\|
キーワード	Cesarean delivery Delivery methods Long-term outcome Child development Outcome-wide approach
発行日	2025-01-20
出版物タイトル	Scientific Reports
巻	15巻
号	1号
出版者	Nature Portfolio
開始ページ	2485
ISSN	2045-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2025
論文のバージョン	publisher
PubMed ID	39833288
DOI	10.1038/s41598-025-87043-2
Web of Science KeyUT	001402008500024
関連URL	isVersionOf https://doi.org/10.1038/s41598-025-87043-2

Identification of factors related to functional prognoses in craniopharyngiomas

フルテキストURL	fulltext.pdf
著者	Umeda, Tsuyoshi\| Otani, Yoshihiro\| Fujii, Kentaro\| Ishida, Joji\| Hirano, Shuichiro\| Suruga, Yasuki\| Kemmotsu, Naoya\| Imoto, Ryoji\| Kegoya, Yasuhito\| Mizuta, Ryo\| Inoue, Yohei\| Hokama, Madoka\| Makihara, Seiichiro\| Hasegawa, Kosei\| Inagaki, Kenichi\| Otsuka, Fumio\| Yasuhara, Takao\| Tanaka, Shota\|
キーワード	Craniopharyngioma Functional prognosis Obesity Tumor size Social participation Hypothalamic involvement
備考	The version of record of this article, first published in Journal of Neuro-Oncology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s11060-024-04925-7\|
発行日	2025-01-22
出版物タイトル	Journal of Neuro-Oncology
巻	172巻
号	2号
出版者	Springer Science and Business Media LLC
開始ページ	471
終了ページ	479
ISSN	0167-594X
NCID	AA10633712
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024
論文のバージョン	publisher
PubMed ID	39841323
DOI	10.1007/s11060-024-04925-7
Web of Science KeyUT	001401916600001
関連URL	isVersionOf https://doi.org/10.1007/s11060-024-04925-7

Frequency and Significance of Body Weight Loss During Immunochemotherapy in Patients with Advanced Non-Small Cell Lung Cancer

フルテキストURL	fulltext.pdf
著者	Taoka, Masataka\| Ichihara, Eiki\| Yokoyama, Toshihide\| Inoue, Koji\| Tamura, Tomoki\| Sato, Akiko\| Oda, Naohiro\| Kano, Hirohisa\| Nakamura, Kayo\| Kawai, Haruyuki\| Inoue, Masaaki\| Ochi, Nobuaki\| Fujimoto, Nobukazu\| Ichikawa, Hirohisa\| Ando, Chihiro\| Oze, Isao\| Kiura, Katsuyuki\| Maeda, Yoshinobu\| Hotta, Katsuyuki\|
キーワード	non-small cell lung cancer body weight loss immune checkpoint inhibitors chemotherapy
発行日	2024-12-06
出版物タイトル	Cancers
巻	16巻
号	23号
出版者	MDPI
開始ページ	4089
ISSN	2072-6694
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 by the authors.
論文のバージョン	publisher
PubMed ID	39682275
DOI	10.3390/cancers16234089
Web of Science KeyUT	001376843000001
関連URL	isVersionOf https://doi.org/10.3390/cancers16234089

In vitro fertilization and long-term child health and development: nationwide birth cohort study in Japan

フルテキストURL	fulltext.pdf
著者	Matsumoto, Naomi\| Mitsui, Takashi\| Kadowaki, Tomoka\| Mitsuhashi, Toshiharu\| Hirota, Tomoya\| Masuyama, Hisashi\| Yorifuji, Takashi\|
キーワード	In vitro fertilization (IVF) Assisted reproductive technology (ART) Long-term outcome Development
発行日	2024-11-18
出版物タイトル	European Journal of Pediatrics
巻	184巻
号	1号
出版者	Springer Science and Business Media LLC
開始ページ	24
ISSN	1432-1076
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© The Author(s) 2024
論文のバージョン	publisher
PubMed ID	39557744
DOI	10.1007/s00431-024-05883-y
Web of Science KeyUT	001363062300001
関連URL	isVersionOf https://doi.org/10.1007/s00431-024-05883-y

Distribution and Incorporation of Extracellular Vesicles into Chondrocytes and Synoviocytes

フルテキストURL	fulltext.pdf
著者	Ohtsuki, Takashi\| Sato, Ikumi\| Takashita, Ren\| Kodama, Shintaro\| Ikemura, Kentaro\| Opoku, Gabriel\| Watanabe, Shogo\| Furumatsu, Takayuki\| Yamada, Hiroshi\| Ando, Mitsuru\| Akiyoshi, Kazunari\| Nishida, Keiichiro\| Hirohata, Satoshi\|
キーワード	extracellular vesicles (EVs) chondrocytes synoviocytes osteoarthritis (OA)
発行日	2024-11-06
出版物タイトル	International Journal of Molecular Sciences
巻	25巻
号	22号
出版者	MDPI
開始ページ	11942
ISSN	1661-6596
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 by the authors.
論文のバージョン	publisher
DOI	10.3390/ijms252211942
Web of Science KeyUT	001365437300001
関連URL	isVersionOf https://doi.org/10.3390/ijms252211942

Effect of Radon Inhalation on Murine Brain Proteins: Investigation Using Proteomic and Multivariate Analyses

JaLCDOI	10.18926/AMO/67663
フルテキストURL	78_5_387.pdf
著者	Naoe, Shota\| Tanaka, Ayumi\| Kanzaki, Norie\| Takenaka, Reiju\| Sakoda, Akihiro\| Miyaji, Takaaki\| Yamaoka, Kiyonori\| Kataoka, Takahiro\|
抄録	Radon is a known risk factor for lung cancer; however, it can be used beneficially, such as in radon therapy. We have previously reported the enhancement of antioxidant effects associated with trace amounts of oxidative stress as one of the positive biological effects of radon inhalation. However, the biological effects of radon inhalation are incompletely understood, and more detailed and comprehensive studies are required. Although several studies have used proteomics to investigate the effects of radon inhalation on body proteins, none has focused on brain proteins. In this study, we evaluated the expression status of proteins in murine brains using proteomic and multivariate analyses to identify those whose expressions changed following two days of radon inhalation at a concentration of 1,500 Bq/m3. We found associations of radon inhalation with the expressions of seven proteins related to neurotransmission and heat shock. These proteins may be proposed as biomarkers indicative of radon inhalation. Although further studies are required to obtain the detailed biological significance of these protein alterations, this study contributes to the elucidation of the biological effects of radon inhalation as a low-dose radiation.
キーワード	radon inhalation proteomics multivariate analysis brain oxidative stress
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2024-10
巻	78巻
号	5号
出版者	Okayama University Medical School
開始ページ	387
終了ページ	399
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	39467657
Web of Science KeyUT	001343346400005

Optimising the oral midazolam dose for premedication in people with intellectual disabilities and/or autism spectrum disorder

フルテキストURL	fulltext.pdf
著者	Higuchi, Hitoshi\| Miyake, Kota\| Miyake, Saki\| Fujimoto, Maki\| Nishioka, Yukiko\| Maeda, Shigeru\| Miyawaki, Takuya\|
キーワード	autism spectrum disorder intellectual disabilities oral midazolam premedication sedation
発行日	2024-06-11
出版物タイトル	Journal of Applied Research in Intellectual Disabilities
巻	37巻
号	4号
出版者	Wiley
開始ページ	e13265
ISSN	1360-2322
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	© 2024 The Author(s).
論文のバージョン	publisher
PubMed ID	38859732
DOI	10.1111/jar.13265
Web of Science KeyUT	001242656000001
関連URL	isVersionOf https://doi.org/10.1111/jar.13265

The Impact of Reduced Skeletal Muscle Mass on Patients with Knee Osteoarthritis

JaLCDOI	10.18926/AMO/67199
フルテキストURL	78_3_245.pdf
著者	Akagawa, Manabu\| Saito, Hidetomo\| Takahashi, Yasuhiro\| Iwamoto, Yosuke\| Iida, Junpei\| Yoshikawa, Takayuki\| Abe, Toshiki\| Saito, Kimio\| Kijima, Hiroaki\| Kasukawa, Yuji\| Hongo, Michio\| Miyakoshi, Naohisa\|
抄録	Although several studies have suggested a possible association between sarcopenia and knee osteoarthritis (OA) in the elderly, there remains no definitive evidence. Recently, however, the serum creatinine/cystatin C ratio (sarcopenia index: SI) was reported to correlate with skeletal muscle mass. The present retrospective study therefore investigated the impact of reduced skeletal muscle mass on advanced knee OA using SI. In 55 individuals scheduled for knee osteotomy or knee arthroplasty, correlations between SI and patient-reported outcomes such as the Knee Society Score (KSS), Knee Injury and Osteoarthritis Outcome Score (KOOS), and Oxford Knee Score (OKS) were explored. Significant associations were found between SI and the KSS functional activity score (β=0.37; p=0.022), KOOS subscale for activities of daily living (β=0.42; p=0.0096), and OKS (β=0.42; p=0.0095). This study underscores the role of reduced muscle mass in functional outcomes and introduces SI as a valuable marker for assessing muscle loss in knee OA patients.
キーワード	knee osteoarthritis sarcopenia index reduced muscle mass activities of daily living functional activity
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2024-06
巻	78巻
号	3号
出版者	Okayama University Medical School
開始ページ	245
終了ページ	250
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38902212
Web of Science KeyUT	001267351000005

Breastfeeding at 6 months of age had a positive impact on overweight and obesity in Japanese adolescents at 15 years of age

フルテキストURL	K0006999_abstract_review.pdf K0006999_fulltext.pdf K0006999_summary.pdf
著者	門脇知花\|
発行日	2024-03-25
資料タイプ	学位論文
学位授与番号	甲第6999号
学位授与年月日	2024-03-25
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語
著作権者	© 2022 Foundation Acta Paediatrica.

Reduced Immunogenicity of COVID-19 Vaccine in Obese Patients with Type 2 Diabetes: A Cross-Sectional Study

フルテキストURL	K0006964_abstract_review.pdf K0006964_fulltext.pdf K0006964_summary.pdf
著者	髙橋寛子\|
発行日	2024-03-25
資料タイプ	学位論文
学位授与番号	甲第6964号
学位授与年月日	2024-03-25
学位・専攻分野	博士（医学）
授与大学	岡山大学
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School

Reduced Immunogenicity of COVID-19 Vaccine in Obese Patients with Type 2 Diabetes: A Cross-Sectional Study

JaLCDOI	10.18926/AMO/66927
フルテキストURL	78_2_185.pdf
著者	Takahashi, Hiroko\| Eguchi, Jun\| Watanabe, Mayu\| Nakayama, Masanori\| Wada, Jun\|
抄録	The global pandemic of coronavirus infection 2019 (COVID-19) was an unprecedented public health emergency. Several clinical studies reported that heart disease, lung disease, diabetes, hypertension, dyslipidemia, and obesity are critical risk factors for increased severity of and hospitalization for COVID-19. This is largely because patients with these underlying medical conditions can show poor immune responses to the COVID-19 vaccinations. Diabetes is one of the underlying conditions most highly associated with COVID-19 susceptibility and is considered a predictor of poor prognosis of COVID-19. We therefore investigated factors that influence the anti-SARS-CoV-2 spike IgG antibody titer after three doses of vaccination in patients with type 2 diabetes. We found that obesity was associated with low anti-SARS-CoV-2 spike IgG antibody titers following three-dose vaccination in type 2 diabetics. Obese patients with type 2 diabetes may have attenuated vaccine efficacy and require additional vaccination; continuous infection control should be considered in such patients.
キーワード	obesity type 2 diabetes COVID-19 vaccination
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2024-04
巻	78巻
号	2号
出版者	Okayama University Medical School
開始ページ	185
終了ページ	191
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	Copyright Ⓒ 2024 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	38688836
Web of Science KeyUT	001227932200002