検索結果 - 岡山大学学術成果リポジトリ

Preparation of Enteric-coated Capsules of Beclomethasone Dipropionate for Patients with Intestinal Graft-versus-Host Disease and a Case Study

JaLCDOI	10.18926/AMO/51868
フルテキストURL	67_5_319.pdf
著者	Murakawa, Kiminaka\| Sato, Tomoaki\| Maeda, Yoshinobu\| Kitamura, Yoshihisa\| Tanimoto, Mitsune\| Sendo, Toshiaki\|
抄録	Graft-versus-host disease (GVHD) is a major concern in transplantation patients. Gut GVHD is accompanied by diarrhea, abdominal pain, and/or melena. Although oral treatment with corticosteroids (CSs) is effective in treating gut GVHD, it can cause adverse reactions that affect the entire body. Topical administration of CSs can be effective in treating diseases in which lesions are limited locally, because adverse reactions can then be alleviated. In this study, we examine and discuss an enteric-coated beclomethasone dipropionate (BDP) capsule (BDP-EC) formulated at Okayama University Hospital. The BDP-EC did not dissolve in solution 1 (pH1.2), and began disintegrating in solution 2 (pH6.8) after 5min, with a mean dissolution rate at 15min of 85%. We then used the capsule to treat a patient who developed gut GVHD after allogeneic hematopoietic stem cell transplantation. Clinically, the frequency of diarrhea decreased after BDP-EC administration. In addition, we were able to decrease the prednisolone equivalent dose. Symptoms associated with adverse reactions to BDP were not observed during the hospitalization period. These findings suggest that the administration of BDP-EC in the early stages of gut GVHD may allow a reduction in the initial doses of systemic CSs.
キーワード	beclomethasone intestinal graft-versus-host disease enteric-coated capsule in-hospital formulation
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2013-10
巻	67巻
号	5号
出版者	Okayama University Medical School
開始ページ	319
終了ページ	324
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	24145732
Web of Science KeyUT	000325836100006

Occult Compression Fracture of Metacarpal Head without Evidence of Avascular Necrosis

JaLCDOI	10.18926/AMO/51867
フルテキストURL	67_5_311.pdf
著者	Nishida, Keiichiro\| Hashizume, Hiroyuki\| Matsukawa, Akihiro\| Hashizume, Kenzo\| Shimamura, Yasunori\| Torigoe, Yasuyuki\| Ozaki, Toshifumi\|
抄録	We report a case of 4th metacarpal head collapse of a 19-year-old healthy man. MRI revealed T1 low and T2 high regions in the collapsed 4th metacarpal head, as well as in the right 3rd and left 4th metacarpal head. Our initial diagnosis was occult compression fracture due to avascular necrosis, known as Dieterich's disease. However, pathological findings of surgically resected right 4th metacarpal head were compatible with transient osteoporosis and metacarpal head fracture followed by active tissue repair. The autologous osteochondral transplants from costchondral junction survived and maintained their size and shape even at 10-year follow-up.
キーワード	occult compression fracture metacarpal head avascular necrosis osteochondral autograft
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2013-10
巻	67巻
号	5号
出版者	Okayama University Medical School
開始ページ	311
終了ページ	317
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	24145731
Web of Science KeyUT	000325836100005

Double Congenital Fistulae with Aneurysm Diagnosed by Combining Imaging Modalities

JaLCDOI	10.18926/AMO/51866
フルテキストURL	67_5_305.pdf
著者	Tachibana, Motomi\| Mukouhara, Naoki\| Hirami, Ryouichi\| Fujio, Hideki\| Yumoto, Akihisa\| Watanuki, Yutaka\| Hayashi, Aiko\| Suminoe, Isao\| Koudani, Hiroshi\|
抄録	Congenital coronary pulmonary artery fistula (CAF) is rare, and systemic-to-pulmonary artery fistula (SPAF) is even more so. Furthermore, congenital coronary pulmonary fistula associated with congenital SPAF is extremely rare. As far as we know, CAF and SPAF connected with an aneurysm have not been described very often. We described an 83-year-old woman with an aneurysm originating from a CAF connected to an aortopulmonary artery fistula. Chest radiography revealed a shadow at the left edge of the heart line. Multi-detector-row computed tomography (MDCT) with contrast enhancement and coronary cine angiography revealed that the shadow was an aneurysm connected to a tortuous fistula at the left anterior descending coronary artery. The aneurysm was formed by congenital coronary pulmonary and aortopulmonary artery fistulae. Echocardiography revealed predominantly systolic blood flow in the fistula from the left anterior descending coronary artery (LAD). Although neither MDCT, echocardiography nor coronary angiography alone could provide a comprehensive image of the anomaly, including the hemodynamics in the fistulae and their relationship with surrounding organs and tissues, their combination could provided important facts the led to a deeper understanding of this very uncommon occurrence.
キーワード	coronary pulmonary artery fistula aortopulmonary artery fistula aneurysm
Amo Type	Case Report
出版物タイトル	Acta Medica Okayama
発行日	2013-10
巻	67巻
号	5号
出版者	Okayama University Medical School
開始ページ	305
終了ページ	309
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	24145730
Web of Science KeyUT	000325836100004

Inhibitory Function and Working Memory in Attention Deficit/Hyperactivity Disorder and Pervasive Developmental Disorders:Does a Continuous Cognitive Gradient Explain ADHD and PDD Traits?

JaLCDOI	10.18926/AMO/51865
フルテキストURL	67_5_293.pdf
著者	Takeuchi, Akihito\| Ogino, Tatsuya\| Hanafusa, Kaoru\| Morooka, Teruko\| Oka, Makio\| Yorifuji, Takashi\| Ohtsuka, Yoko\|
抄録	To clarify the relationship between attention deficit/hyperactivity disorder (AD/HD) and pervasive developmental disorders (PDD), we investigated the common features and differences of these disorders in neuropsychological profiles. The subjects were 4 groups of Japanese boys aged 6 to 15 years, categorized by diagnosis:AD/HD (n＝20), PDD with comorbid AD/HD (PDD＋:n＝16), PDD without comorbid AD/HD (PDD－:n＝8), and typically developing (n＝60). We evaluated executive function (EF) through verbal and visuospatial memory tasks, the Go/NoGo task, and the color-word matching Stroop task. We performed a categorical analysis to estimate the effects of the 3 disorders on EF and a dimensional analysis to estimate the effects of symptom scales on EF. We found that the AD/HD and PDD＋ subjects had negative effects on verbal working memory and intra-individual response variability. The severity of these impairments was positively correlated with the inattentiveness score. The subjects with a PDD＋ or PDD－ diagnosis had poorer scores on interference control;the severity of this impairment was correlated with the PDD symptom score. Impairments in visuospatial working memory were detected in the AD/HD and PDD－ groups but not in the PDD＋ group. Impairments in inhibition of the pre-potent response were noted in all 3 categories. AD/HD and PDD share neuropsychological features, though each disorder has a specific impairment pattern. Our findings partially support the idea that AD/HD and PDD are on a spectrum.
キーワード	attention deficit/hyperactivity disorder pervasive developmental disorder executive function working memory color-word matching Stroop task
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2013-10
巻	67巻
号	5号
出版者	Okayama University Medical School
開始ページ	293
終了ページ	303
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	24145729
Web of Science KeyUT	000325836100003
関連URL	http://ousar.lib.okayama-u.ac.jp/metadata/52244

Is Presence or History of Extracolonic Primary Malignancy a Risk for Colorectal Neoplasia? An Analysis of Patients Who Underwent Colonoscopy

JaLCDOI	10.18926/AMO/51864
フルテキストURL	67_5_285.pdf
著者	Akita, Mitsuhiro\| Hiraoka, Sakiko\| Kaji, Eisuke\| Takemoto, Koji\| Nagahara, Yasuhiro\| Yamamoto, Hiroshi\| Yamamoto, Kazuhide\| Kato, Jun\|
抄録	Whether presence or history of extracolonic primary malignancy is a risk for colorectal neoplasia is not fully known. In this study, 26,452 first-time colonoscopy cases were examined using a colonoscopy database. Among the analyzed subjects, 3,026 (11%) subjects had history or concomitance of extracolonic primary malignancy, while the remaining 23,426 subjects did not. Colorectal neoplasia was observed in 39% of all the subjects. A crude comparison showed that the prevalence of any type of colorectal neoplasia was higher in subjects with extracolonic malignancy than in those without (42% vs. 39%, p＝0.0012). However, after adjusting for confounding factors, the odds ratios (ORs) of subjects with extracolonic malignancy for having colorectal neoplasia, advanced neoplasia, and cancer were all less than 1.0, and all significantly different from those of subjects without extracolonic malignancy. Analysis according to the type of extracolonic malignancy revealed that gastric cancer cases had a significantly lower risk for colorectal advanced neoplasia (OR:0.81;95% CI:0.67-0.99). Among major malignancies, only esophageal squamous cell cancer cases had increased risk for colorectal neoplasia (OR:1.66;95% CI:1.20-2.29). Patients with presence or history of extracolonic malignancy did not carry a higher risk of occurrence of colorectal neoplasia.
キーワード	colorectal cancer colonoscopy risk factor database
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2013-10
巻	67巻
号	5号
出版者	Okayama University Medical School
開始ページ	285
終了ページ	292
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	24145728
Web of Science KeyUT	000325836100002

Relationship between Orthodontic Expertise and Perception of Need for Orthodontic Treatment for Mandibular Protrusion in Japan

JaLCDOI	10.18926/AMO/51863
フルテキストURL	67_5_277.pdf
著者	Murakami, Takashi\| Fujii, Akihito\| Kawabata, Yuya\| Takakura, Hiroaki\| Yamaue, Rie\| Tarek Abdulsamad Ali Balam\| Kuroda, Shingo\| Kawanabe, Noriaki\| Kamioka, Hiroshi\| Yamashiro, Takashi\|
抄録	The aims of this study were to investigate how the Peer Assessment Rating (PAR index) predicts the perceived need for orthodontic treatment of mandibular protrusion in Japanese subjects, and to elucidate whether the perceived need for treatment was affected by the ratersʼ orthodontic expertise. The subjects were 110 dental students and 32 orthodontists. We showed them casts of 10 untreated mandibular protrusion cases and gave them a questionnaire in which they had to describe their perceptions of the orthodontic treatment needs using a 10-point visual analog scale (VAS). The PAR index was used for cast evaluation. The PAR index scores showed significant correlations with the VAS scores. In casts with a low PAR score, there were no differences in the VAS scores between orthodontists and students. In casts with a PAR score greater than 23, the orthodontists perceived a significantly greater treatment need than did the students;for scores of 22, 28, and 29, students who had received orthodontic treatment themselves were more likely to perceive the treatment need. The PAR index is a good clinical predictor for assessing the perceived treatment needs for mandibular protrusion. Perception of the need for orthodontic treatment for mandibular protrusion depended on the degree of orthodontic expertise in Japanese subjects.
キーワード	orthodontic expertise treatment need PAR index mandibular protrusion
Amo Type	Original Article
出版物タイトル	Acta Medica Okayama
発行日	2013-10
巻	67巻
号	5号
出版者	Okayama University Medical School
開始ページ	277
終了ページ	283
ISSN	0386-300X
NCID	AA00508441
資料タイプ	学術雑誌論文
言語	英語
著作権者	CopyrightⒸ 2013 by Okayama University Medical School
論文のバージョン	publisher
査読	有り
PubMed ID	24145727
Web of Science KeyUT	000325836100001

J.H.クラパム『近代イギリス経済史　第1巻　第2編　初期鉄道時代，1820−1850年』要綱，第14章

JaLCDOI	10.18926/OER/51694
タイトル（別表記）	J.H. Clapham, An Economic History of Modern Britain, vol.1, Book 2, The Early Railway Age, 1820-1850 (1st ed., 1926, 2nd ed. with corrections, 1939), Outline, Chap. 14
フルテキストURL	oer_045_2_087_113.pdf
著者	一ノ瀬篤\|
出版物タイトル	岡山大学経済学会雑誌
発行日	2013-09-20
巻	45巻
号	2号
開始ページ	87
終了ページ	113
ISSN	0386-3069
言語	日本語
著作権者	Copyright © 2013 岡山大学経済学会
論文のバージョン	publisher
NAID	120005326908

地方交付税の合併算定替え終了が市町村に及ぼす影響 ―財源調整機能は維持されるか―

JaLCDOI	10.18926/OER/51693
タイトル（別表記）	A Study on the Expiration of the Calculation upon Mergers of Local Tax Allocation - Do Intergovernmental Fiscal Relations Keep Working? -
フルテキストURL	oer_045_2_059_085.pdf
著者	太田裕二\| 平野正樹\|
出版物タイトル	岡山大学経済学会雑誌
発行日	2013-09-20
巻	45巻
号	2号
開始ページ	59
終了ページ	85
ISSN	0386-3069
言語	日本語
著作権者	Copyright © 2013 岡山大学経済学会
論文のバージョン	publisher
NAID	120005326907

労働金庫の財務分析

JaLCDOI	10.18926/OER/51692
タイトル（別表記）	Financial Analysis of Labor Bank
フルテキストURL	oer_045_2_025_058.pdf
著者	三村聡\|
出版物タイトル	岡山大学経済学会雑誌
発行日	2013-09-20
巻	45巻
号	2号
開始ページ	25
終了ページ	58
ISSN	0386-3069
言語	日本語
著作権者	Copyright © 2013 岡山大学経済学会
論文のバージョン	publisher
NAID	120005326906

地方公共団体の文化政策：創造都市岡山市の可能性

JaLCDOI	10.18926/OER/51691
タイトル（別表記）	Cultural policy of local government - Possibility of Creative City “Okayama” -
フルテキストURL	oer_045_2_001_024.pdf
著者	友延由紀恵\| 中村良平\|
出版物タイトル	岡山大学経済学会雑誌
発行日	2013-09-20
巻	45巻
号	2号
開始ページ	1
終了ページ	24
ISSN	0386-3069
言語	日本語
著作権者	Copyright © 2013 岡山大学経済学会
論文のバージョン	publisher
NAID	120005326905

Comparison of serum ferritin and oxidative stress biomarkers between Japanese workers with and without metabolic syndrome

著者	Iwanaga, Suketaka\| Sakano, Noriko\| Taketa, Kazuhisa\| Takahashi, Noriko\| Wang, Da-Hong\| Takahashi, Hidekazu\| Kubo, Masayuki\| Miyatake, Nobuyuki\| Ogino, Keiki\|
発行日	2013-02-01
出版物タイトル	Obesity Research & Clinical Practice
資料タイプ	学術雑誌論文

Serum oxidative-anti-oxidative stress balance is dysregulated in patients with hepatitis C virus-related hepatocellular carcinoma

著者	Nishimura, Mamoru\| Takaki, Akinobu\| Tamaki, Naofumi\| Maruyama, Takayuki\| Onishi, Hideki\| Kobayashi, Sayo\| Nouso, Kazuhiro\| Yasunaka, Tetsuya\| Koike, Kazuko\| Hagihara, Hiroaki\| Kuwaki, Kenji\| Nakamura, Shinichiro\| Ikeda, Fusao\| Iwasaki, Yoshiaki\| Tomofuji, Takaaki\| Morita, Manabu\| Yamamoto, Kazuhide\|
発行日	2013-01-30
出版物タイトル	Hepatology Research
巻	43巻
号	10号
資料タイプ	学術雑誌論文

CD14 upregulation as a distinct feature of non-alcoholic fatty liver disease after pancreatoduodenectomy

フルテキストURL	WorldJHepatology_5_4_189-195.pdf
著者	Satoh, Daisuke\| Yagi, Takahito\| Nagasaka, Takeshi\| Shinoura, Susumu\| Umeda, Yuzo\| Yoshida, Ryuichi\| Utsumi, Masashi\| Tanaka, Takehiro\| Sadamori, Hiroshi\| Fujiwara, Toshiyoshi\|
キーワード	Non-alcoholic fatty liver disease Pancreatoduodenectomy CD14 Endotoxin Kupffer cells
発行日	2013-04-27
出版物タイトル	World Journal of Hepatology
巻	5巻
号	4号
開始ページ	189
終了ページ	195
資料タイプ	学術雑誌論文
言語	英語
OAI-PMH Set	岡山大学
著作権者	©2013 Baishideng Publishing Group Co., Limited. All rights reserved.
論文のバージョン	publisher
DOI	10.4254/wjh.v5.i4.189
オフィシャル URL	http://www.wjgnet.com/1948-5182/full/v5/i4/189.htm\|
関連URL	http://ousar.lib.okayama-u.ac.jp/metadata/51448

Improved syntheses of D-ribo- and 2-deoxy-D-ribofuranose phospho sugars from methyl β-D-ribopyranoside

著者	Hanaya, Tadashi\| Koga, Yuko\| Kawamoto, Heizan\| Yamamoto, Hiroshi\|
発行日	2007-12
出版物タイトル	Heterocycles
巻	73巻
号	1号
資料タイプ	学術雑誌論文

A New Route for Preparation of 2-Deoxy-D-ribofuranose Phospho Sugar

著者	Hanaya, Tadashi\| Tsukui, Hiroyuki\| Igi, Naomi\| Noguchi, Ayashi\| Kawamoto, Heizan\| Yamamoto, Hiroshi\|
発行日	2007-04-13
出版物タイトル	Heterocycles
巻	72巻
号	1号
資料タイプ	学術雑誌論文

Synthesis of 2-Acetamido-2,5-dideoxy-5-phosphoryl-D-glucopyranose Derivatives: New Phospha-sugar Analogs of N-Acetyl-D-glucosamine

著者	Hanaya, Tadashi\| Kawaguchi, Masahiro\| Sumi, Masakazu\| Makino, Kazuo\| Tsukada, Keiko\| Yamamoto, Hiroshi\|
発行日	2012-12-31
出版物タイトル	Heterocycles
巻	86巻
号	2号
資料タイプ	学術雑誌論文

Mitochondrial Localization of ABC Transporter ABCG2 and Its Function in 5-Aminolevulinic Acid-Mediated Protoporphyrin IX Accumulation

著者	Kobuchi, Hirotsugu\| Moriya, Koko\| Ogino, Tetsuya\| Fujita, Hirofumi\| Inoue, Keiji\| Shuin, Taro\| Yasuda, Tatsuji\| Utsumi, Kozo\| Utsumi, Toshihiko\|
発行日	2012-11-26
出版物タイトル	PLoS ONE
巻	7巻
号	11号
資料タイプ	学術雑誌論文

First Synthesis of a Natural Isoxanthopterin Glycoside, Asperopterin-A

著者	Hanaya, Tadashi\| Ejiri, Kazumasa\| Yamamoto, Hiroshi\|
発行日	2012-01-01
出版物タイトル	Heterocycles
巻	84巻
号	2号
資料タイプ	学術雑誌論文

裏表紙・英文目次

著者	岡山大学文学部\|
発行日	2013-07-25
出版物タイトル	岡山大学文学部紀要
巻	59巻
資料タイプ	その他

劉白聯句訳注稿(十六)

著者	橘英範\|
発行日	2013-07-25
出版物タイトル	岡山大学文学部紀要
巻	59巻
資料タイプ	紀要論文
JaLCDOI	10.18926/okadai-bun-kiyou/51516